Compounds > caprylates
Page last updated: 2024-09-03

caprylates and indomethacin

caprylates has been researched along with indomethacin in 9 studies

Compound Research Comparison

Studies
(caprylates)		Trials
(caprylates)		Recent Studies (post-2010)
(caprylates)		Studies
(indomethacin)		Trials
(indomethacin)		Recent Studies (post-2010) (indomethacin)
5,0611002,33929,5271,8383,396

Protein Interaction Comparison

ProteinTaxonomycaprylates (IC50)indomethacin (IC50)
Chain A, membrane-associated prostaglandin E synthase-2Macaca fascicularis (crab-eating macaque)1000
Prostaglandin-H2 D-isomeraseMus musculus (house mouse)1.1
Multidrug resistance-associated protein 4Homo sapiens (human)5.8
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.9994
Prostaglandin G/H synthase 2 Bos taurus (cattle)0.7764
Cytochrome c oxidase subunit 2Homo sapiens (human)0.34
Prostaglandin G/H synthase 1Ovis aries (sheep)0.5605
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)0.004
Interleukin-8Homo sapiens (human)0.05
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)0.004
Aldo-keto reductase family 1 member B1Homo sapiens (human)6
Aldo-keto reductase family 1 member B1Bos taurus (cattle)5
Prostaglandin G/H synthase 1Mus musculus (house mouse)0.011
Prostaglandin G/H synthase 1Homo sapiens (human)0.4848
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)0.2
Thromboxane-A synthase Homo sapiens (human)0.1
Indoleamine 2,3-dioxygenase 1Mus musculus (house mouse)0.082
Nitric oxide synthase, inducibleMus musculus (house mouse)4.5
Substance-P receptorCavia porcellus (domestic guinea pig)5.7
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)0.2
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)0.2
Prostaglandin G/H synthase 2Homo sapiens (human)1.5128
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)0.5504
Aldo-keto reductase family 1 member C3Homo sapiens (human)3.4486
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)0.2
C-X-C chemokine receptor type 3Homo sapiens (human)0.05
Aldo-keto reductase family 1 member C2 Homo sapiens (human)8.97
Prostaglandin G/H synthase 2Ovis aries (sheep)3.4647
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.4233
Solute carrier family 22 member 6Homo sapiens (human)3
Sigma intracellular receptor 2Rattus norvegicus (Norway rat)0.49
Rho-associated protein kinase 2Rattus norvegicus (Norway rat)7.7
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)0.5461
P2Y purinoceptor 12Rattus norvegicus (Norway rat)0.96

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19904 (44.44)18.7374
1990's2 (22.22)18.2507
2000's0 (0.00)29.6817
2010's3 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Garnier, J; Salesse, R1
Kristev, A; Lukanov, J; Mitkov, D1
Chapkynov, P; Kristev, A; Lukanov, Y; Mitkov, D1
Jumbasova, S; Kostadinova, I; Krustev, A; Mitkov, D; Toreva, D1
Bluestone, R; Kippen, I; Klinenberg, JR; Whitehouse, MW1
Chapleau, MW; Li, Z; Su, X1
He, JK; Huan, D; Liu, Y; Xiao, L; Yi, T1
Di, H; He, JK; Liu, Y; Xiao, L; Yi, T1
Xiao, L; Yi, T1

Other Studies

9 other study(ies) available for caprylates and indomethacin

ArticleYear
Effects of drugs on pigeon erythrocyte membrane and asymmetric control or adenylate cyclase by the lipid bilayer.
    Biochimica et biophysica acta, 1979, Jun-13, Volume: 554, Issue:1

    Topics: Adenylyl Cyclases; Alprenolol; Animals; Caprylates; Chlorpromazine; Columbidae; Dinitrophenols; Erythrocyte Membrane; Erythrocytes; Indomethacin; Membrane Lipids; Receptors, Adrenergic; Receptors, Adrenergic, beta; Tetracaine; Trinitrobenzenes

1979
Effects of the medium chain octanoic fatty acid on the contractile activity of vascular smooth muscle tissues.
    Folia medica, 1992, Volume: 34, Issue:1

    Topics: Animals; Caprylates; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Electrophysiology; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth, Vascular; Prostaglandins

1992
The effect of octanoic fatty acid on the cardiovascular system of the guinea pig.
    Cor et vasa, 1989, Volume: 31, Issue:4

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Caprylates; Cardiac Output; Cardiovascular Diseases; Cardiovascular System; Dinoprostone; Guinea Pigs; Hepatic Encephalopathy; Humans; Indomethacin; Liver Cirrhosis; Male; Syndrome; Vascular Resistance

1989
On octanoic acid-induced hyperventilation--implications for hepatic encephalopathy and Reye's syndrome.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1989, Volume: 189, Issue:5

    Topics: Alkalosis, Respiratory; Animals; Blood Pressure; Caprylates; Electroencephalography; Hepatic Encephalopathy; Hyperventilation; Indomethacin; Injections, Intravenous; Rabbits; Reye Syndrome

1989
Effect of some uricosuric and anti-inflammatory drugs on the binding of uric acid to human serum albumin in vitro.
    The Journal of laboratory and clinical medicine, 1970, Volume: 76, Issue:1

    Topics: Allopurinol; Anti-Inflammatory Agents; Aspirin; Binding Sites; Caprylates; Colchicine; Dialysis; Fluorescence; Humans; In Vitro Techniques; Indomethacin; Mefenamic Acid; Phenylbutazone; Probenecid; Protein Binding; Serum Albumin; Sodium Salicylate; Sulfinpyrazone; Uric Acid; Uricosuric Agents

1970
Role of cyclooxygenase metabolites in mediating platelet-induced baroreceptor dysfunction.
    The American journal of physiology, 1995, Volume: 269, Issue:2 Pt 2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Blood Platelets; Caprylates; Carotid Arteries; Female; Indomethacin; Male; Platelet Activation; Pressoreceptors; Pressure; Prostaglandin Endoperoxides, Synthetic; Prostaglandin-Endoperoxide Synthases; Rabbits; Sulfonamides; Thrombin; Thromboxane A2; Thromboxane-A Synthase; Vasoconstriction

1995
[Use of an in vitro lipolysis model to evaluate type I lipid formulations].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2010, Volume: 45, Issue:10

    Topics: Caprylates; Chromatography, High Pressure Liquid; Digestion; Excipients; Glycerides; Indomethacin; Lipolysis; Models, Biological; Polyethylene Glycols; Solubility; Suspensions

2010
[Establishment and evaluation of a dynamic in vitro intestinal absorption model of lipid formulations].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2011, Volume: 46, Issue:8

    Topics: Animals; Calcium; Caprylates; Digestion; Glucose; Glycerides; Indomethacin; Intestinal Absorption; Lipids; Lipolysis; Models, Biological; Potassium; Rats; Rats, Sprague-Dawley

2011
[Mechanisms of hydroxypropyl methylcellulose for the precipitation inhibitor of supersaturatable self-emulsifying drug delivery systems].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2013, Volume: 48, Issue:5

    Topics: Caprylates; Chemical Precipitation; Crystallization; Drug Delivery Systems; Emulsifying Agents; Emulsions; Ethylene Glycols; Glycerides; Hypromellose Derivatives; Indomethacin; Lipolysis; Molecular Weight; Polyethylene Glycols; Viscosity

2013