Page last updated: 2024-08-24

capecitabine and folic acid

capecitabine has been researched along with folic acid in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (37.50)29.6817
2010's8 (50.00)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Kornek, GV; Locker, GJ; Mader, RM; Pluschnig, U; Scheithauer, W; Steger, GG; Wenzel, C1
Clippe, C; Freyer, G; Milano, G; Trillet-Lenoir, V1
Beale, P; Clarke, SJ; Horvath, L; Ong, S; Rivory, L; Sharma, R1
Assenat, E; Duffour, J; Ychou, M1
Arnheim, KE1
Fukuda, T; Shiroiwa, T; Tsutani, K1
Jennings, BA; Kwok, CS; Loke, YK; Matthews, V; Wawruch, P; Willis, G1
Peng, X; Wei, K; Zou, F1
Jennings, BA; Willis, G1
Chay, WY; Chia, JWK; Choo, SP; Dent, RA; Koh, KX; Koo, WH; Kwok, LL; Lo, SK; Loh, M; Mok, ZY; Ng, RCH; Soong, RCT; Syn, N; Tan, S; Tham, CK; Toh, HC; Wong, NS; Yap, YS1
Al-Ramadhani, H; Al-Yacoub, S; Kadi, T; Tantawi, DA; Yousef, AM; Zawiah, M1
Chan, AK; Chan, SL; Ma, BB1
de Gramont, A; Glimelius, B; Marshall, J; Stintzing, S; Yoshino, T1
Bhinge, SD; Bhutkar, MA; Gavade, AS; Jadhav, NR; Randive, DS; Shejawal, KP1

Reviews

5 review(s) available for capecitabine and folic acid

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Irinotecan for the treatment of metastatic colorectal cancer].
    Bulletin du cancer, 2006, Volume: 93, Issue:5

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Clinical Trials as Topic; Colorectal Neoplasms; Deoxycytidine; Fluorouracil; Folic Acid; Humans; Irinotecan; Maximum Tolerated Dose; Multicenter Studies as Topic; Pharmacogenetics

2006
Functional polymorphisms of folate metabolism and response to chemotherapy for colorectal cancer, a systematic review and meta-analysis.
    Pharmacogenetics and genomics, 2012, Volume: 22, Issue:4

    Topics: Capecitabine; Colorectal Neoplasms; Databases, Genetic; Deoxycytidine; Fluorouracil; Folic Acid; Gene Expression Regulation, Neoplastic; Genetic Association Studies; Genetic Variation; Genotype; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Tetrahydrofolate Dehydrogenase; Thymidylate Synthase

2012
How folate metabolism affects colorectal cancer development and treatment; a story of heterogeneity and pleiotropy.
    Cancer letters, 2015, Jan-28, Volume: 356, Issue:2 Pt A

    Topics: Capecitabine; Colorectal Neoplasms; Deoxycytidine; Fluorouracil; Folic Acid; Folic Acid Antagonists; Folic Acid Deficiency; Genetic Heterogeneity; Genetic Pleiotropy; Genetic Variation; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Thymidylate Synthase

2015
Metastatic colorectal cancer: Advances in the folate-fluoropyrimidine chemotherapy backbone.
    Cancer treatment reviews, 2021, Volume: 98

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Colorectal Neoplasms; Fluorouracil; Folic Acid; Humans; Irinotecan; Leucovorin; Oxaliplatin; Prognosis

2021

Trials

4 trial(s) available for capecitabine and folic acid

ArticleYear
Capecitabine treatment results in increased mean corpuscular volume of red blood cells in patients with advanced solid malignancies.
    Anti-cancer drugs, 2003, Volume: 14, Issue:2

    Topics: Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Erythrocyte Indices; Erythrocytes; Female; Fluorouracil; Folic Acid; Hematinics; Homocysteine; Humans; Male; Middle Aged; Neoplasms; Prospective Studies; Retrospective Studies; Thymidylate Synthase; Vitamin B 12

2003
A phase II study of fixed-dose capecitabine and assessment of predictors of toxicity in patients with advanced/metastatic colorectal cancer.
    British journal of cancer, 2006, Apr-10, Volume: 94, Issue:7

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Diarrhea; Disease Progression; Fatigue; Female; Fluorouracil; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Neoplasm Metastasis; Predictive Value of Tests; Survival Analysis

2006
Cost-effectiveness analysis of XELOX for metastatic colorectal cancer based on the NO16966 and NO16967 trials.
    British journal of cancer, 2009, Jul-07, Volume: 101, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Colorectal Neoplasms; Cost-Benefit Analysis; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Folic Acid; Health Care Costs; Humans; Male; Middle Aged; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin; Quality of Life; Retrospective Studies; Treatment Outcome

2009
Predictors of Hand-Foot Syndrome and Pyridoxine for Prevention of Capecitabine-Induced Hand-Foot Syndrome: A Randomized Clinical Trial.
    JAMA oncology, 2017, Nov-01, Volume: 3, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Asian People; Capecitabine; Chi-Square Distribution; Dihydrouracil Dehydrogenase (NADP); Double-Blind Method; Drug Administration Schedule; Female; Folic Acid; Genetic Predisposition to Disease; Genome-Wide Association Study; Hand-Foot Syndrome; Humans; Incidence; Intracellular Signaling Peptides and Proteins; Kaplan-Meier Estimate; Logistic Models; Male; Membrane Proteins; Microfilament Proteins; Middle Aged; Multivariate Analysis; Neoplasms; Odds Ratio; Pharmacogenomic Variants; Polymorphism, Single Nucleotide; Predictive Value of Tests; Pyridoxine; Risk Assessment; Risk Factors; Severity of Illness Index; Singapore; Time Factors; Treatment Outcome

2017

Other Studies

7 other study(ies) available for capecitabine and folic acid

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Lethal toxicity of capecitabine due to abusive folic acid prescription?
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2003, Volume: 15, Issue:5

    Topics: Antimetabolites, Antineoplastic; Breast Neoplasms; Capecitabine; Deoxycytidine; Drug Interactions; Female; Fluorouracil; Folic Acid; Humans; Middle Aged

2003
[Therapy of colorectal carcinoma. To combine saves lives].
    MMW Fortschritte der Medizin, 2004, Jan-15, Volume: 146, Issue:1-2

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Colorectal Neoplasms; Deoxycytidine; Fluorouracil; Folic Acid; Humans; Multicenter Studies as Topic; Organoplatinum Compounds; Oxaliplatin; Palliative Care; Randomized Controlled Trials as Topic; Time Factors; Vitamin B Complex

2004
Folate-decorated PEG-PLGA nanoparticles with silica shells for capecitabine controlled and targeted delivery.
    International journal of pharmaceutics, 2014, Apr-10, Volume: 464, Issue:1-2

    Topics: Capecitabine; Delayed-Action Preparations; Deoxycytidine; Drug Delivery Systems; Fluorouracil; Folic Acid; Nanoparticles; Polyesters; Polyethylene Glycols; Silicon Dioxide

2014
The association of polymorphisms in folate-metabolizing genes with response to adjuvant chemotherapy of colorectal cancer.
    Cancer chemotherapy and pharmacology, 2018, Volume: 82, Issue:2

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Colorectal Neoplasms; Dihydrouracil Dehydrogenase (NADP); Female; Fluorouracil; Folic Acid; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Tetrahydrofolate Dehydrogenase; Young Adult

2018
Association of serum folate level with toxicity of capecitabine in patients with colorectal cancers: a prospective cohort study.
    Hong Kong medical journal = Xianggang yi xue za zhi, 2018, Volume: 24 Suppl 3, Issue:3

    Topics: Aged; Antimetabolites, Antineoplastic; Capecitabine; Colorectal Neoplasms; Female; Folic Acid; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Prospective Studies

2018
Colon targeted dosage form of Capecitabine using folic acid anchored modified carbon nanotube:
    Drug development and industrial pharmacy, 2021, Volume: 47, Issue:9

    Topics: Apoptosis; Capecitabine; Colon; Folic Acid; Nanotubes, Carbon

2021