cantharidin has been researched along with demethylcantharidin in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 16 (57.14) | 29.6817 |
| 2010's | 11 (39.29) | 24.3611 |
| 2020's | 1 (3.57) | 2.80 |
| Authors | Studies |
|---|---|
| Baldwin, ML; Bowyer, MC; Collins, E; McCluskey, A; Sakoff, JA | 1 |
| Ackland, SP; Bowyer, MC; Gardiner, E; McCluskey, A; Sakoff, JA; Walkom, C | 1 |
| Bowyer, MC; Keane, MA; McCluskey, A; Sakoff, JA; Sim, AT; Walkom, CC; Young, DJ | 1 |
| Chamberlin, AR; Hart, ME; McCluskey, A; Sakoff, JA; Walkom, C | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Ackland, SP; Gilbert, J; Hill, TA; McCluskey, A; Sakoff, JA; Sauer, B; Stewart, SG | 2 |
| Ackland, SP; Gilbert, J; Hill, TA; McCluskey, A; Sakoff, JA; Stewart, SG | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Gilbert, J; McCluskey, A; Sakoff, JA; Scott, JL; Thaqi, A | 1 |
| Chou, MC; Hwang, JM; Su, CJ; Yeh, CB | 1 |
| Bajsa, J; Duke, SO; Gordon, CP; Hill, TA; McCluskey, A; Sahu, R; Stewart, SG; Tekwani, BL | 1 |
| Au-Yeung, SC; Ho, YP; To, KK | 2 |
| Au-Yeung, SC; Ho, YP; To, KK; Wang, X; Yu, CW | 1 |
| Au-Yeung, SC; Ho, YP; Li, KK; Pang, SK; Yu, CW | 1 |
| Au-Yeung, SC; Ho, YP; Pang, SK; Yu, CW | 1 |
| Au-Yeung, SC; Guan, H; Ho, YP; Pang, SK; Yu, CW | 1 |
| Arion, VB; Galanski, M; Jakupec, MA; Keppler, BK; Reithofer, MR; Valiahdi, SM | 1 |
| Gu, JY; Lin, QY; Yang, Q; Zhang, F; Zhang, LL; Zheng, XL | 1 |
| Chen, MM; Li, SK; Lin, QY; Wang, PP; Zhang, F; Zhao, YL | 1 |
| Huang, Y; Jing, X; Li, X; Li, Y; Meng, F; Xiao, H; Zhou, D | 1 |
| Gui, P; Hu, WL; Lin, QY; Shen, ST; Song, WJ; Zhang, F | 1 |
| Huang, Y; Jing, X; Sun, X; Wang, E; Xie, Z; Xiong, H; Zhou, D | 1 |
| Au-Yeung, CF; Ho, YP; Pang, SK; So, WK | 1 |
| Chen, X; Huang, Y; Jing, X; Wu, Y; Xie, Z; Zhang, Q; Zhou, D | 1 |
| Che, SA; Cui, PF; Gong, JH; He, YJ; Jiang, HL; Jin, T; Luo, CQ; Lyu, JY; Qiao, JB; Xing, L; Zhang, JL; Zhang, M | 1 |
| Cheng, P; Duan, H; He, S; Li, J; Pu, K; Zeng, Z; Zhang, C | 1 |
28 other study(ies) available for cantharidin and demethylcantharidin
| Article | Year |
|---|---|
Anhydride modified cantharidin analogues: synthesis, inhibition of protein phosphatases 1 and 2A and anticancer activity.
Topics: Anhydrides; Antineoplastic Agents; Cantharidin; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Isoenzymes; Phosphoprotein Phosphatases; Tumor Cells, Cultured | 2000 |
Cantharimides: a new class of modified cantharidin analogues inhibiting protein phosphatases 1 and 2A.
Topics: Bridged Bicyclo Compounds, Heterocyclic; Cantharidin; Enzyme Inhibitors; Histidine; Models, Molecular; Molecular Structure; Phosphoprotein Phosphatases; Structure-Activity Relationship | 2001 |
The first two cantharidin analogues displaying PP1 selectivity.
Topics: Cantharidin; Enzyme Inhibitors; Indicators and Reagents; Phosphoprotein Phosphatases; Structure-Activity Relationship; Substrate Specificity | 2002 |
Modified norcantharidins; synthesis, protein phosphatases 1 and 2A inhibition, and anticancer activity.
Topics: Animals; Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Cell Division; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Phosphoprotein Phosphatases | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Heterocyclic substituted cantharidin and norcantharidin analogues--synthesis, protein phosphatase (1 and 2A) inhibition, and anti-cancer activity.
Topics: Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Cantharidin; Enzyme Inhibitors; Heterocyclic Compounds; Humans; Inhibitory Concentration 50; Phosphoprotein Phosphatases; Protein Phosphatase 1; Structure-Activity Relationship; Tumor Cells, Cultured | 2007 |
Norcantharimides, synthesis and anticancer activity: Synthesis of new norcantharidin analogues and their anticancer evaluation.
Topics: Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Neoplasms; Structure-Activity Relationship; Tumor Cells, Cultured | 2007 |
Synthesis and biological evaluation of norcantharidin analogues: towards PP1 selectivity.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Erythrocytes; Humans; Molecular Structure; Muscle, Skeletal; Protein Phosphatase 1; Protein Phosphatase 2; Rabbits; Stereoisomerism; Structure-Activity Relationship | 2007 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Synthesis and biological activity of Delta-5,6-norcantharimides: importance of the 5,6-bridge.
Topics: Antineoplastic Agents; Cantharidin; Cell Line, Tumor; Enzyme Inhibitors; Humans; Molecular Structure; Stereoisomerism | 2010 |
Therapeutic effects of cantharidin analogues without bridging ether oxygen on human hepatocellular carcinoma cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cantharidin; Carcinoma, Hepatocellular; Cell Line, Tumor; Ethers; Hepatocytes; Humans; Inhibitory Concentration 50; Liver Neoplasms; Oxygen; Rats | 2010 |
The antiplasmodial activity of norcantharidin analogs.
Topics: Amino Acid Sequence; Animals; Antimalarials; Bridged Bicyclo Compounds, Heterocyclic; Humans; Molecular Sequence Data; Plasmodium falciparum; Sequence Homology, Amino Acid | 2010 |
Determination of the release of hydrolyzed demethylcantharidin from novel traditional chinese medicine-platinum compounds with anticancer activity by gas chromatography.
Topics: Cantharidin; Gas Chromatography-Mass Spectrometry; Hydrolysis; Medicine, Chinese Traditional; Reproducibility of Results; Sensitivity and Specificity | 2002 |
Protein phosphatase 2A inhibition and circumvention of cisplatin cross-resistance by novel TCM-platinum anticancer agents containing demethylcantharidin.
Topics: Antineoplastic Agents, Phytogenic; Cantharidin; Cisplatin; Cross-Linking Reagents; DNA Repair; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Humans; Male; Medicine, Chinese Traditional; Organoplatinum Compounds; Phosphoprotein Phosphatases; Protein Phosphatase 2; Structure-Activity Relationship; Time Factors; Tumor Cells, Cultured | 2004 |
Synergistic interaction between platinum-based antitumor agents and demethylcantharidin.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Body Weight; Cantharidin; Carboplatin; Carcinoma, Hepatocellular; Cisplatin; Drug Interactions; Humans; Leukemia; Liver Neoplasms; Mice; Mice, Nude; Organoplatinum Compounds; Oxaliplatin; Tumor Cells, Cultured | 2005 |
Anticancer activity of a series of platinum complexes integrating demethylcantharidin with isomers of 1,2-diaminocyclohexane.
Topics: Antineoplastic Agents; Apoptosis; Cantharidin; Carboplatin; Carcinoma, Hepatocellular; Cell Cycle; Cisplatin; Colorectal Neoplasms; Cyclohexylamines; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Flow Cytometry; Humans; Isomerism; Liver Neoplasms; Organoplatinum Compounds; Oxaliplatin; Platinum; Tumor Cells, Cultured | 2006 |
DNA damage induced by novel demethylcantharidin-integrated platinum anticancer complexes.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cantharidin; Cell Line, Tumor; Colorectal Neoplasms; DNA Damage; DNA, Neoplasm; Humans; Platinum | 2007 |
Impact of oxaliplatin and a novel DACH-platinum complex in the gene expression of HCT116 colon cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cantharidin; Cell Line, Tumor; Colonic Neoplasms; Gene Expression; Humans; Oligonucleotide Array Sequence Analysis; Organoplatinum Compounds; Oxaliplatin; Platinum Compounds | 2008 |
Novel endothall-containing platinum(IV) complexes: synthesis, characterization, and cytotoxic activity.
Topics: Antineoplastic Agents; Cantharidin; Cell Line, Tumor; Cell Survival; Crystallography, X-Ray; Dicarboxylic Acids; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Molecular Structure; Organoplatinum Compounds; Platinum | 2008 |
Crystal structures, interactions with biomacromolecules and anticancer activities of Mn(II), Ni(II), Cu(II) complexes of demethylcantharate and 2-aminopyridine.
Topics: Aminopyridines; Antineoplastic Agents; Binding Sites; Cantharidin; Cell Line, Tumor; Cell Proliferation; Copper; Crystallography, X-Ray; Humans; Manganese; Nickel; Organometallic Compounds; Protein Binding; Serum Albumin, Bovine; Spectrum Analysis; Viscosity | 2012 |
Synthesis, interaction with DNA and bovine serum albumin of the transition metal complexes of demethylcantharate and 2-aminobenzothiazole.
Topics: Animals; Antineoplastic Agents; Benzothiazoles; Cantharidin; Carcinoma, Hepatocellular; Cattle; Cell Line, Tumor; Cell Proliferation; Coordination Complexes; Crystallography, X-Ray; DNA; Humans; Liver Neoplasms; Models, Molecular; Serum Albumin, Bovine; Stomach Neoplasms; Transition Elements | 2012 |
A polymer-(tandem drugs) conjugate for enhanced cancer treatment.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cantharidin; Cell Line, Tumor; Liver Neoplasms; Mice; Nanocapsules; Platinum; Polymers; Treatment Outcome | 2013 |
Interaction with biomacromolecules and antiproliferative activities of Mn(II), Ni(II), Zn(II) complexes of demethylcantharate and 2,2'-bipyridine.
Topics: 2,2'-Dipyridyl; Animals; Antineoplastic Agents; Cantharidin; Cattle; Cell Line, Tumor; Cell Proliferation; Coordination Complexes; Crystallography, X-Ray; DNA; Humans; Manganese; Models, Molecular; Neoplasms; Nickel; Serum Albumin, Bovine; Zinc | 2013 |
Co-delivery of oxaliplatin and demethylcantharidin via a polymer-drug conjugate.
Topics: Cantharidin; Cell Line, Tumor; Humans; Micelles; Microscopy, Confocal; Neoplasms; Organoplatinum Compounds; Oxaliplatin; Polymers | 2014 |
East-west fusion-necrosis and apoptosis acting in concert by demethylcantharidin-integrated platinum complexes.
Topics: Antineoplastic Agents; Apoptosis; Cantharidin; Carboplatin; Cisplatin; Coordination Complexes; DNA Adducts; HCT116 Cells; Humans; Inhibitory Concentration 50; Light; Necrosis; Optical Imaging; Organoplatinum Compounds; Platinum; Pyridines; Scattering, Radiation | 2014 |
Dual-Sensitive Charge-Conversional Polymeric Prodrug for Efficient Codelivery of Demethylcantharidin and Doxorubicin.
Topics: Animals; Antibiotics, Antineoplastic; Cantharidin; Carcinoma, Hepatocellular; Doxorubicin; Drug Delivery Systems; Female; Humans; Hydrogen-Ion Concentration; Liver Neoplasms; Mice; Nanoparticles; Polymers; Prodrugs; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2016 |
One-step assembly of polymeric demethylcantharate prodrug/Akt1 shRNA complexes for enhanced cancer therapy.
Topics: Acrylates; Antineoplastic Agents; Cantharidin; Cell Line, Tumor; Cell Movement; Cell Survival; DNA; Drug Liberation; Green Fluorescent Proteins; Humans; Hydrolysis; Polymerization; Polymers; Prodrugs; Proto-Oncogene Proteins c-akt; RNA, Small Interfering | 2016 |
Charge-Reversal Polymer Nano-modulators for Photodynamic Immunotherapy of Cancer.
Topics: Animals; Antineoplastic Agents; Cantharidin; Colonic Neoplasms; Immunologic Factors; Immunotherapy; Mice; Mice, Inbred BALB C; Molecular Structure; Nanomedicine; Nanoparticles; Neoplasms, Experimental; Particle Size; Photochemotherapy; Polymers | 2021 |