Page last updated: 2024-08-21

canrenone and aldosterone

canrenone has been researched along with aldosterone in 45 studies

Research

Studies (45)

Timeframe	Studies, this research(%)	All Research%
pre-1990	19 (42.22)	18.7374
1990's	6 (13.33)	18.2507
2000's	9 (20.00)	29.6817
2010's	8 (17.78)	24.3611
2020's	3 (6.67)	2.80

Authors

Authors	Studies
Haga, N; Ishibashi, M; Itoh, T; Kamata, S; Matsui, T; Nakamura, M; Odaguchi, K; Shimizu, T; Suzuki, T; Yamada, F	1
Chinn, LJ; Desai, BN; Salamon, KW	1
Aumelas, A; Auzou, G; Claire, M; Faraj, H; Grassy, G; Rondot, A	1
Claire, M; Corvol, P; Menard, J; Michaud, A; Rafestin-Oblin, ME; Roth-Meyer, C	1
Hofmann, LM; Pedrera, HA; Suleymamov, OD	1
Al-Dujaili, EA; Huston, GJ	1
Erkkola, R; Lammintausta, R	1
Aupetit, B; Duchier, J; Legrand, JC	1
Erbler, HC	1
Appenheimer, M; Glänzer, K; Herschbach, ML; Krück, F; Lucas, R; Vetter, H; Weiand, H; Witassek, F	1
Erbler, HC; Hilfenhaus, M; Wernze, H	1
Cheng, SC; Harding, BW; Sadee, W; Suzuki, K	1
Erbler, HC; Hilfenhaus, M	1
Hofmann, LM; Maibach, HI; Polk, RC	1
Christ, M; Theisen, K; Wehling, M	1
Käsmayr, J; Theisen, K; Wehling, M	2
Lewicka, S; Vecsei, P; Weindel, K	1
Boucher, RC; Gatzy, JT; Knowles, MR	1
Buse, M; Casals-Stenzel, J; Losert, W	1
Aperia, A; Larsson, L; Zetterström, R	1
Claire, M; Corvol, P; Geering, K; Oblin, ME; Rossier, B	1
Hettiarachchi, J; Ramsay, LE	1
Colby, HD; Los, LE	1
Aktas, J; Christ, M; Eisen, C; Theisen, K; Wehling, M	1
Frömter, E; Rabe, A	1
Sanderson, JE	1
Casaburi, C; Cittadini, A; Di Gianni, A; Monti, MG; Saccà, L; Saldamarco, L; Scherillo, G; Serpico, R; Vanasia, M	1
Caligiuri, A; De Franco, RM; Failli, P; Geerts, A; Gentilini, A; Gentilini, P; Marra, F; Mazzetti, L; Meucci, M; Pinzani, M; Romanelli, RG; Rombouts, K; Vanasia, M	1
Fumeaux, Z; Mach, F; Martin, PY; Perneger, T; Rossier, M; Saudan, P; Schnetzler, B; Stoermann, C	1
Armanini, D; Calò, LA; Davis, PA; De Mozzi, P; Fiore, C; Martire, G; Pagnin, E; Sartorato, P; Zaghetto, F	1
Brunette, MG; Couchourel, D; Leclerc, M	1
Boccanelli, A; Cacciatore, G; Clemenza, F; De Maria, R; de Simone, G; Di Lenarda, A; Gavazzi, A; Gonzini, L; Latini, R; Maggioni, AP; Masson, S; Mureddu, GF; Porcu, M; Vanasia, M	1
Armanini, D; Calò, LA; Fiore, C; Pagnin, E; Ragazzi, E; Sartorato, P	1
Bowalgaha, K; Knights, KM; Miners, JO	1
Agostoni, P; Boccanelli, A	1
Bianchi, L; Bonaventura, A; D'Angelo, A; Derosa, G; Fogari, E; Maffioli, P; Romano, D	1
Armanini, D; Bordin, L; Clari, G; Donà, G; Sabbadin, C	1
D'Elia, E; Krum, H	1
Bianchi, L; D'Angelo, A; Derosa, G; Maffioli, P; Romano, D	1
Channar, PA; El-Seedi, H; Faisal, M; Larik, FA; Mehfooz, H; Saeed, A; Shahzad, D	1
Caroccia, B; Domening, O; Iacobone, M; Lenzini, L; Pallafacchina, G; Piazza, M; Poglitsch, M; Prisco, S; Rizzuto, R; Rossi, GP; Seccia, TM; Zanin, S	1
Ceolotto, G; Cesari, M; Maiolino, G; Rossi, GP; Rossitto, G; Seccia, TM	1
Armanini, D; Boscaro, M; Sabbadin, C	1
Avataneo, V; Bertello, C; Buffolo, F; Burrello, J; D'Avolio, A; Mengozzi, G; Monticone, S; Mulatero, P; Pecori, A; Rabbia, F; Rumbolo, F; Veglio, F	1

Reviews

3 review(s) available for canrenone and aldosterone

Article	Year
Spirolactones: clinical and pharmacologic studies. Advances in nephrology from the Necker Hospital, 1977, Volume: 7 Topics: Aldosterone; Animals; Binding, Competitive; Canrenoic Acid; Canrenone; Diuresis; Humans; Hyperaldosteronism; Hypertension; In Vitro Techniques; Kidney; Mineralocorticoid Receptor Antagonists; Pregnadienes; Protein Binding; Rats; Receptors, Cell Surface; Spironolactone	1977
Mechanism of the antimineralocorticoid effects of spirolactones. Kidney international, 1981, Volume: 20, Issue:1 Topics: Aldosterone; Animals; Anura; Canrenoic Acid; Canrenone; Cattle; Guinea Pigs; Humans; Male; Mineralocorticoid Receptor Antagonists; Rats; Receptors, Steroid; Spironolactone; Veratrum Alkaloids	1981
Synthetic approaches towards the multi target drug spironolactone and its potent analogues/derivatives. Steroids, 2017, Volume: 118 Topics: Aldosterone; Androstadienes; Androstenes; Animals; Canrenone; Chloranil; Dehydroepiandrosterone; Eplerenone; Humans; Molecular Structure; Receptors, Mineralocorticoid; Spironolactone	2017

Trials

5 trial(s) available for canrenone and aldosterone

Article	Year
Spironolactone in thiazide-induced hypokalaemia: variable response between patients. British journal of clinical pharmacology, 1981, Volume: 11, Issue:2 Topics: Adult; Aldosterone; Benzothiadiazines; Canrenone; Diuretics; Electrolytes; Female; Humans; Hypokalemia; Male; Middle Aged; Potassium; Sodium Chloride Symporter Inhibitors; Spironolactone	1981
Safety of low-dose spironolactone administration in chronic haemodialysis patients. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2003, Volume: 18, Issue:11 Topics: Adult; Aged; Aldosterone; Canrenone; Humans; Hyperkalemia; Kidney Failure, Chronic; Middle Aged; Mineralocorticoid Receptor Antagonists; Potassium; Renal Dialysis; Spironolactone	2003
Baseline characteristics of patients recruited in the AREA IN-CHF study (Antiremodelling Effect of Aldosterone Receptors Blockade with Canrenone in Mild Chronic Heart Failure). Journal of cardiovascular medicine (Hagerstown, Md.), 2007, Volume: 8, Issue:9 Topics: Aged; Aldosterone; Biomarkers; Canrenone; Disease Progression; Double-Blind Method; Echocardiography; Female; Heart Failure; Humans; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Ventricular Dysfunction, Left; Ventricular Remodeling	2007
Effects of canrenone in patients with metabolic syndrome. Expert opinion on pharmacotherapy, 2013, Volume: 14, Issue:16 Topics: Aged; Aldosterone; Blood Glucose; Blood Pressure; C-Reactive Protein; Canrenone; Female; Humans; Insulin Resistance; Male; Metabolic Syndrome; Middle Aged; Mineralocorticoid Receptor Antagonists; Natriuretic Peptide, Brain; Tumor Necrosis Factor-alpha	2013
The effects of canrenone on inflammatory markers in patients with metabolic syndrome. Annals of medicine, 2015, Volume: 47, Issue:1 Topics: Aged; Aldosterone; Biomarkers; Blood Glucose; Blood Pressure; Body Mass Index; Body Weight; Canrenone; Creatine; Double-Blind Method; Fasting; Female; Humans; Inflammation; Lipids; Lipoproteins; Male; Metabolic Syndrome; Metalloproteases; Middle Aged; Natriuretic Peptide, Brain; Peroxidase; Potassium; White People	2015

Other Studies

37 other study(ies) available for canrenone and aldosterone

Article	Year
Aldosterone antagonists. 2. Synthesis and biological activities of 11,12-dehydropregnane derivatives. Journal of medicinal chemistry, 1987, Volume: 30, Issue:9 Topics: Adrenalectomy; Animals; Kidney; Male; Mineralocorticoid Receptor Antagonists; Rats; Rats, Inbred Strains; Receptors, Androgen; Receptors, Mineralocorticoid; Receptors, Progesterone; Receptors, Steroid; Structure-Activity Relationship	1987
A structure-activity relationship study of spirolactones. Contribution of the cyclopropane ring to antimineralocorticoid activity. Journal of medicinal chemistry, 1981, Volume: 24, Issue:9 Topics: Chemical Phenomena; Chemistry; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; Molecular Conformation; Receptors, Mineralocorticoid; Receptors, Steroid; Spironolactone; Structure-Activity Relationship	1981
Synthesis of new 11 beta-substituted spirolactone derivatives. Relationship with affinity for mineralocorticoid and glucocorticoid receptors. Journal of medicinal chemistry, 1993, Aug-06, Volume: 36, Issue:16 Topics: Adrenalectomy; Aldosterone; Animals; Dexamethasone; Kidney; Rabbits; Receptors, Glucocorticoid; Spironolactone; Structure-Activity Relationship	1993
Aldosterone antagonism studies in the rhesus monkey. The Journal of pharmacology and experimental therapeutics, 1977, Volume: 202, Issue:1 Topics: Administration, Oral; Aldosterone; Animals; Canrenone; Diuresis; Dose-Response Relationship, Drug; Female; Haplorhini; Hydrochlorothiazide; Injections, Intramuscular; Macaca mulatta; Mineralocorticoid Receptor Antagonists; Potassium; Sodium; Spironolactone	1977
A comparison of some extra-renal effects of spironolactone and canrenone. British journal of clinical pharmacology, 1979, Volume: 7, Issue:4 Topics: Aldosterone; Canrenone; Humans; Male; Membrane Potentials; Middle Aged; Mineralocorticoid Receptor Antagonists; Pregnadienes; Pressure; Rectum; Spironolactone; Time Factors	1979
Effect of spironolactone treatment on the renin-aldosterone system during pregnancy. International journal of clinical pharmacology and biopharmacy, 1979, Volume: 17, Issue:7 Topics: Aldosterone; Canrenone; Female; Humans; Potassium; Pregnancy; Renin; Sodium; Spironolactone; Time Factors	1979
[Effect of spironolactones on aldosterone synthesis and adrenal metabolism]. Annales d'endocrinologie, 1978, Volume: 39, Issue:5 Topics: Adrenal Glands; Aldosterone; Animals; Canrenoic Acid; Canrenone; Ducks; Hydroxylation; Mineralocorticoid Receptor Antagonists; Mitochondria; Mitochondria, Liver; Oxidative Phosphorylation; Sheep; Spironolactone; Steroid Hydroxylases	1978
Effect of spironolactone and its main metabolite canrenone on the renin-angiotensin-aldosterone-system during long-term treatment in rats. Acta endocrinologica, 1979, Volume: 90, Issue:1 Topics: Administration, Oral; Aldosterone; Angiotensin II; Animals; Canrenone; Dose-Response Relationship, Drug; Male; Pregnadienes; Rats; Renin; Spironolactone; Time Factors; Water-Electrolyte Balance	1979
Effect of a spirolactone on plasma and urinary aldosterone in primary aldosteronism. Hormone research, 1977, Volume: 8, Issue:1 Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Canrenone; Female; Glucuronates; Humans; Hyperaldosteronism; Kinetics; Potassium; Pregnadienes; Renin	1977
Effect of aldosterone antagonist canrenone on plasma aldosterone concentration and plasma renin activity, and on the excretion of aldosterone and electrolytes by man. European journal of clinical pharmacology, 1976, Feb-06, Volume: 9, Issue:4 Topics: Aldosterone; Canrenone; Diabetes Mellitus; Diuresis; Dose-Response Relationship, Drug; Female; Humans; Methods; Middle Aged; Potassium; Pregnadienes; Renin; Sodium	1976
Effects of spironolactone, canrenone and canrenoate-K on cytochrome P450, and 11beta- and 18-hydroxylation in bovine and human adrenal cortical mitochondria. Endocrinology, 1976, Volume: 99, Issue:4 Topics: Adenoma; Adrenal Cortex; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Animals; Canrenoic Acid; Canrenone; Cattle; Cytochrome P-450 Enzyme System; Humans; Hyperplasia; Mitochondria; Oxidation-Reduction; Pregnadienes; Spectrum Analysis; Spironolactone; Steroid Hydroxylases	1976
Proceedings: Acute and chronic effects of the aldosterone antagonist spironolactone and its main metabolite canrenone on plasma aldosterone concentration, plasma renin activity, serum electrolytes and on the excretion of aldosterone, fluid and electrolyte Naunyn-Schmiedeberg's archives of pharmacology, 1975, Volume: 287 Suppl Topics: Aldosterone; Animals; Canrenone; Electrolytes; Male; Pregnadienes; Rats; Renin; Spironolactone	1975
Renal clearance of canrenoate in normal man. Clinical pharmacology and therapeutics, 1975, Volume: 18, Issue:6 Topics: 17-Ketosteroids; Aldosterone; Canrenoic Acid; Canrenone; Humans; Hydroxysteroids; Kidney; Kidney Function Tests; Male; Metabolic Clearance Rate; Pregnadienes; Renin	1975
High affinity aldosterone binding to plasma membrane rich fractions from mononuclear leukocytes: is there a membrane receptor for mineralocorticoids? Biochemical and biophysical research communications, 1991, Dec-31, Volume: 181, Issue:3 Topics: Aldosterone; Binding, Competitive; Canrenone; Cell Membrane; Cloning, Molecular; Humans; Hydrocortisone; Kinetics; Leukocytes, Mononuclear; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Receptors, Steroid; Recombinant Proteins	1991
Rapid effects of mineralocorticoids on sodium-proton exchanger: genomic or nongenomic pathway? The American journal of physiology, 1991, Volume: 260, Issue:5 Pt 1 Topics: Aldosterone; Calcium; Canrenoic Acid; Canrenone; Carrier Proteins; Dexamethasone; DNA; Humans; Hydrocortisone; In Vitro Techniques; Kinetics; Leukocytes, Mononuclear; Models, Biological; Potassium; Propionates; Reference Values; Sodium; Sodium-Hydrogen Exchangers	1991
Aldosterone influences free intracellular calcium in human mononuclear leukocytes in vitro. Cell calcium, 1990, Volume: 11, Issue:9 Topics: Adolescent; Adult; Aged; Aldosterone; Amiloride; Calcium; Canrenoic Acid; Canrenone; Corticosterone; Cycloheximide; Dactinomycin; Humans; Hydrocortisone; Leukocytes, Mononuclear; Middle Aged	1990
Comparative dose-effect studies with four C-17-spirosteroidal mineralocorticoid synthesis inhibitors. Journal of steroid biochemistry, 1989, Volume: 34, Issue:1-6 Topics: Aldosterone; Analysis of Variance; Animals; Canrenone; Male; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; Oxazoles; Pregnadienes; Rats; Rats, Inbred Strains; Spiro Compounds; Spironolactone; Zona Glomerulosa	1989
Aldosterone metabolism and transepithelial potential difference in normal and cystic fibrosis subjects. Pediatric research, 1985, Volume: 19, Issue:7 Topics: Adult; Aldosterone; Canrenone; Cystic Fibrosis; Electrophysiology; Epithelium; Female; Humans; Male; Nose; Rectum; Reference Values; Spironolactone	1985
Progestogens with antimineralocorticoid activity. Arzneimittel-Forschung, 1985, Volume: 35, Issue:2 Topics: Adrenalectomy; Aldosterone; Androstadienes; Androstenes; Animals; Canrenoic Acid; Canrenone; Cyproterone; Dose-Response Relationship, Drug; Male; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; Norethindrone; Norgestrel; Norpregnenes; Potassium; Progesterone; Progesterone Congeners; Rats; Rats, Inbred Strains; Sodium; Spironolactone	1985
Hormonal induction of Na-K-ATPase in developing proximal tubular cells. The American journal of physiology, 1981, Volume: 241, Issue:4 Topics: Aging; Aldosterone; Animals; Betamethasone; Canrenone; Dose-Response Relationship, Drug; Enzyme Induction; Estrogens; Kidney Tubules, Proximal; Male; Rats; Receptors, Glucocorticoid; Sodium-Potassium-Exchanging ATPase	1981
Binding of spironolactone metabolites in vivo to renal mineralocorticoid receptors in guinea pigs. Pharmacology, 1994, Volume: 48, Issue:2 Topics: Aldosterone; Animals; Binding, Competitive; Canrenone; Guinea Pigs; Kidney; Male; Receptors, Mineralocorticoid; Spironolactone	1994
The inositol-1,4,5-trisphosphate system is involved in rapid effects of aldosterone in human mononuclear leukocytes. The Journal of clinical endocrinology and metabolism, 1993, Volume: 77, Issue:6 Topics: Adult; Aldosterone; Calcium; Canrenone; Concanavalin A; Humans; Hydrocortisone; Inositol 1,4,5-Trisphosphate; Leukocytes, Mononuclear; Male; Sodium-Hydrogen Exchangers; Terpenes; Thapsigargin	1993
Micromolar concentrations of steroids and of aldosterone antagonists inhibit the outwardly rectifying chloride channel with different kinetics. Pflugers Archiv : European journal of physiology, 2000, Volume: 439, Issue:5 Topics: Aldosterone; Anti-Inflammatory Agents; Canrenone; Chloride Channels; Corticosterone; Cytosol; Dose-Response Relationship, Drug; Estradiol; HT29 Cells; Humans; Hydrocortisone; Ion Channel Gating; Kinetics; Lipids; Mineralocorticoid Receptor Antagonists; Patch-Clamp Techniques; Progesterone; Spironolactone; Testosterone	2000
New treatments for myocardial fibrosis. Cardiovascular drugs and therapy, 2002, Volume: 16, Issue:3 Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Canrenone; Clinical Trials as Topic; Endomyocardial Fibrosis; Heart Failure; Humans; Mineralocorticoid Receptor Antagonists; Myocardial Infarction; Rats; Spironolactone	2002
Effects of canrenone on myocardial reactive fibrosis in a rat model of postinfarction heart failure. Cardiovascular drugs and therapy, 2002, Volume: 16, Issue:3 Topics: Administration, Oral; Aldosterone; Animals; Canrenone; Collagen; Cyclodextrins; Disease Models, Animal; Dose-Response Relationship, Drug; Endomyocardial Fibrosis; gamma-Cyclodextrins; Heart Failure; Hemodynamics; Hydroxyproline; Male; Mineralocorticoid Receptor Antagonists; Myocardial Infarction; Myocardium; Rats; Rats, Sprague-Dawley; Ventricular Function, Left	2002
Antifibrogenic effects of canrenone, an antialdosteronic drug, on human hepatic stellate cells. Gastroenterology, 2003, Volume: 124, Issue:2 Topics: Aldosterone; Amiloride; Calcium; Canrenone; Cell Division; Cell Movement; Cells, Cultured; Extracellular Matrix Proteins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Guanidines; Humans; Hydrogen-Ion Concentration; Intracellular Membranes; Liver; Liver Cirrhosis; Mineralocorticoid Receptor Antagonists; Phosphatidylinositol 3-Kinases; Phosphorylation; Platelet-Derived Growth Factor; Protein-Tyrosine Kinases; Signal Transduction; Sodium-Hydrogen Exchangers; Sulfones; Thrombin	2003
Effect of aldosterone and glycyrrhetinic acid on the protein expression of PAI-1 and p22(phox) in human mononuclear leukocytes. The Journal of clinical endocrinology and metabolism, 2004, Volume: 89, Issue:4 Topics: Adult; Aldosterone; Canrenone; Dose-Response Relationship, Drug; Drug Synergism; Female; Glycyrrhetinic Acid; Humans; Leukocytes, Mononuclear; Male; Membrane Transport Proteins; Mineralocorticoid Receptor Antagonists; NADPH Dehydrogenase; NADPH Oxidases; Phosphoproteins; Plasminogen Activator Inhibitor 1	2004
Aldosterone enhances renal calcium reabsorption by two types of channels. Kidney international, 2004, Volume: 66, Issue:1 Topics: Absorption; Aldosterone; Animals; Biological Transport; Calcium; Calcium Channels, L-Type; Calcium Channels, T-Type; Canrenone; Cycloheximide; Kidney; Kidney Tubules, Distal; Kidney Tubules, Proximal; Kinetics; Membranes; Mineralocorticoid Receptor Antagonists; Protein Synthesis Inhibitors; Rabbits; Second Messenger Systems; Sodium; Spironolactone; Time Factors	2004
Effect of canrenone and amiloride on the prooxidative effect induced by aldosterone in human mononuclear leukocytes in vitro. Journal of endocrinological investigation, 2009, Volume: 32, Issue:11 Topics: Adult; Aldosterone; Amiloride; Canrenone; Female; Humans; Hydrocortisone; Leukocytes, Mononuclear; Male; Mineralocorticoid Receptor Antagonists; NADPH Oxidases; Sodium Channel Blockers	2009
Spironolactone and canrenone inhibit UGT2B7-catalyzed human liver and kidney microsomal aldosterone 18beta-glucuronidation: a potential drug interaction. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:7 Topics: Aldosterone; Binding, Competitive; Canrenoic Acid; Canrenone; Drug Interactions; Glucuronosyltransferase; Humans; Hymecromone; In Vitro Techniques; Kidney; Microsomes; Microsomes, Liver; Spironolactone	2010
[The EMPHASIS-HF study]. Giornale italiano di cardiologia (2006), 2011, Volume: 12, Issue:5 Topics: Aldosterone; Biomarkers; Canrenone; Cause of Death; Double-Blind Method; Early Termination of Clinical Trials; Eplerenone; Female; Heart Failure; Hospitalization; Humans; Hyperkalemia; Male; Mineralocorticoid Receptor Antagonists; Models, Cardiovascular; Molecular Structure; Multicenter Studies as Topic; Myocardial Infarction; Patient Selection; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Research Design; Risk; Spironolactone	2011
Aldosterone receptor blockers spironolactone and canrenone: two multivalent drugs. Expert opinion on pharmacotherapy, 2014, Volume: 15, Issue:7 Topics: Albuminuria; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Canrenone; Humans; Hypertension; Inflammation; Insulin Resistance; Mineralocorticoid Receptor Antagonists; Spironolactone	2014
Mineralcorticoid antagonists in heart failure. Heart failure clinics, 2014, Volume: 10, Issue:4 Topics: Aldosterone; Canrenone; Clinical Trials as Topic; Heart Failure; Humans; Mineralocorticoid Receptor Antagonists	2014
Aldosterone Stimulates Its Biosynthesis Via a Novel GPER-Mediated Mechanism. The Journal of clinical endocrinology and metabolism, 2019, 12-01, Volume: 104, Issue:12 Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Benzodioxoles; Calcium; Canrenone; Cytochrome P-450 CYP11B2; Gene Expression Regulation, Neoplastic; Humans; Mineralocorticoid Receptor Antagonists; Quinolines; Receptor, Angiotensin, Type 1; Receptors, Estrogen; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Tumor Cells, Cultured	2019
Effects of Mineralocorticoid and AT1 Receptor Antagonism on The Aldosterone-Renin Ratio In Primary Aldosteronism-the EMIRA Study. The Journal of clinical endocrinology and metabolism, 2020, 06-01, Volume: 105, Issue:6 Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Canrenone; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hyperaldosteronism; Imidazoles; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Prognosis; Prospective Studies; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Tetrazoles	2020
Primary aldosteronism: considerations about the evaluation of the aldosterone to renin ratio during canrenone treatment. Journal of endocrinological investigation, 2021, Volume: 44, Issue:9 Topics: Aldosterone; Antihypertensive Agents; Canrenone; Diagnostic Techniques, Endocrine; Duration of Therapy; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Mineralocorticoid Receptor Antagonists; Renin; Renin-Angiotensin System; Reproducibility of Results	2021
Mineralocorticoid Receptor Antagonist Effect on Aldosterone to Renin Ratio in Patients With Primary Aldosteronism. The Journal of clinical endocrinology and metabolism, 2021, 08-18, Volume: 106, Issue:9 Topics: Adolescent; Adrenalectomy; Adult; Aged; Aldosterone; Canrenone; Cohort Studies; False Negative Reactions; Female; Guidelines as Topic; Humans; Hyperaldosteronism; Hypertension; Male; Mass Screening; Medication Adherence; Middle Aged; Mineralocorticoid Receptor Antagonists; Potassium; Prospective Studies; Renin; Reproducibility of Results; Young Adult	2021