canrenoic acid has been researched along with canrenone in 36 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (61.11) | 18.7374 |
| 1990's | 5 (13.89) | 18.2507 |
| 2000's | 4 (11.11) | 29.6817 |
| 2010's | 5 (13.89) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Karlmar, KE | 1 |
| Claire, M; Corvol, P; Menard, J; Michaud, A; Rafestin-Oblin, ME; Roth-Meyer, C | 1 |
| Jaeger, H; Rosenthal, J; Specker, M | 1 |
| Abshagen, U; L'age, M; Spörl, S | 1 |
| Aupetit, B; Duchier, J; Legrand, JC | 1 |
| Asbury, M; Harrison, I; Ramsay, L; Shelton, J; Tidd, M | 1 |
| Brown, R; Finn, AM; Sadée, W | 1 |
| Asbury, M; Harrison, I; Ramsay, L; Shelton, J | 1 |
| Caminos-Torres, R; Ma, L; Snyder, PJ | 1 |
| Koch, K; Neubert, P | 1 |
| Abshagen, U; Kuhlmann, J; Rennekamp, H | 1 |
| Cheng, SC; Harding, BW; Sadee, W; Suzuki, K | 1 |
| Hofmann, LM; Maibach, HI; Polk, RC | 1 |
| Käsmayr, J; Theisen, K; Wehling, M | 2 |
| Gentilini, P | 1 |
| Asada, S; Nakae, H; Ohtawa, T | 1 |
| Andriulli, A; Armanini, D; Arrigoni, A; Buzzetti, G; Gindro, T; Karbowiak, I | 1 |
| De Croo, F; De Moerloose, P; Van den Bossche, W | 1 |
| Buse, M; Casals-Stenzel, J; Losert, W | 1 |
| Nagy, O; Radó, JP; Szende, L; Takó, J | 1 |
| Finotti, P; Palatini, P | 1 |
| Mügge, A; Schmitz, W; Scholz, H | 1 |
| Rahn, KH | 1 |
| Claire, M; Corvol, P; Geering, K; Oblin, ME; Rossier, B | 1 |
| Claire, M; Corvol, P; Fournex, R; Michaud, A; Peterfalvi, M; Rousseau, G; Torelli, V | 1 |
| Andriuoli, G; Calignano, A; Cirino, G; Mancuso, F; Pinto, A; Sorrentino, L; Sorrentino, R | 1 |
| Alfieri, C; Autore, G; Calignano, A; Cirino, G; d'Emmanuele de Villa Bianca, R; Pinto, A; Sorrentino, L; Sorrentino, R; Vanasia, M | 1 |
| Dasgupta, A; Datta, P; Saffer, H; Wells, A | 1 |
| Dasgupta, A; Datta, P | 1 |
| Dasgupta, A; Tso, G; Wells, A | 1 |
| Bowalgaha, K; Knights, KM; Miners, JO | 1 |
| Armbruster, D; Cooper, KC; Dasgupta, A; DeFrance, A; Petty, D | 1 |
| Dasgupta, A; Johnson, MJ | 1 |
| Collier, PS; Halliday, HL; Hawwa, AF; Kole, P; McElnay, JC; Millar, M; Millership, JS; Shields, MD; Suyagh, M | 1 |
| Dasgupta, A; Johnson, MJ; Sengupta, TK | 1 |
2 review(s) available for canrenoic acid and canrenone
| Article | Year |
|---|---|
Spirolactones: clinical and pharmacologic studies.
Topics: Aldosterone; Animals; Binding, Competitive; Canrenoic Acid; Canrenone; Diuresis; Humans; Hyperaldosteronism; Hypertension; In Vitro Techniques; Kidney; Mineralocorticoid Receptor Antagonists; Pregnadienes; Protein Binding; Rats; Receptors, Cell Surface; Spironolactone | 1977 |
Mechanism of the antimineralocorticoid effects of spirolactones.
Topics: Aldosterone; Animals; Anura; Canrenoic Acid; Canrenone; Cattle; Guinea Pigs; Humans; Male; Mineralocorticoid Receptor Antagonists; Rats; Receptors, Steroid; Spironolactone; Veratrum Alkaloids | 1981 |
3 trial(s) available for canrenoic acid and canrenone
| Article | Year |
|---|---|
Spironolactone and potassium canrenoate in normal man.
Topics: Canrenoic Acid; Canrenone; Clinical Trials as Topic; Humans; Male; Potassium; Pregnadienes; Sodium; Spironolactone; Time Factors | 1976 |
Canrenone and androgen receptor-active materials in plasma of cirrhotic patients during long-term K-canrenoate or spironolactone therapy.
Topics: Adult; Aged; Ascites; Canrenoic Acid; Canrenone; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Humans; Liver Cirrhosis; Liver Cirrhosis, Alcoholic; Male; Middle Aged; Pregnadienes; Random Allocation; Receptors, Androgen; Recurrence; Spironolactone; Testosterone; Time Factors | 1989 |
Population pharmacokinetic model of canrenone after intravenous administration of potassium canrenoate to paediatric patients.
Topics: Administration, Intravenous; Canrenoic Acid; Canrenone; Child; Child, Preschool; Chromatography, High Pressure Liquid; Critical Care; Female; Half-Life; Humans; Infant; Infant, Newborn; Male; Mineralocorticoid Receptor Antagonists; Models, Biological; Nonlinear Dynamics; Prospective Studies; Tissue Distribution | 2012 |
31 other study(ies) available for canrenoic acid and canrenone
| Article | Year |
|---|---|
Assay and properties of 18-hydroxylation of endogenous and exogenous corticosterone in rat adrenals. Evidence for heterogeneity of 18-hydroxylase activity.
Topics: Adrenal Glands; Animals; Canrenoic Acid; Canrenone; Corticosterone; Gas Chromatography-Mass Spectrometry; Male; Mitochondria; NADPH-Ferrihemoprotein Reductase; Potassium Chloride; Rats; Spironolactone; Steroid Hydroxylases | 1979 |
[Comparative study of relative biovailability of several spironolactone formulations in a steady-state test (author's transl)].
Topics: Adult; Biological Availability; Canrenoic Acid; Canrenone; Female; Humans; Male; Spironolactone; Time Factors | 1979 |
Non-interaction of spironolactone medication and cortisol metabolism in man.
Topics: Canrenoic Acid; Canrenone; Drug Interactions; Humans; Hydrocortisone; Liver Diseases; Spironolactone | 1978 |
[Effect of spironolactones on aldosterone synthesis and adrenal metabolism].
Topics: Adrenal Glands; Aldosterone; Animals; Canrenoic Acid; Canrenone; Ducks; Hydroxylation; Mineralocorticoid Receptor Antagonists; Mitochondria; Mitochondria, Liver; Oxidative Phosphorylation; Sheep; Spironolactone; Steroid Hydroxylases | 1978 |
Tissue distribution of 3H-canrenoate potassium in rabbits.
Topics: Animals; Canrenoic Acid; Canrenone; Female; Pregnadienes; Rabbits; Time Factors | 1977 |
Spironolactone and canrenoate-K: relative potency at steady state.
Topics: Administration, Oral; Adult; Canrenoic Acid; Canrenone; Dose-Response Relationship, Drug; Fludrocortisone; Humans; Male; Potassium; Pregnadienes; Sodium; Solutions; Spironolactone; Tablets; Therapeutic Equivalency; Time Factors | 1977 |
Gynecomastia and semen abnormalities induced by spironolactone in normal men.
Topics: Adult; Canrenoic Acid; Canrenone; Estradiol; Follicle Stimulating Hormone; Gynecomastia; Humans; Luteinizing Hormone; Male; Pituitary Gland; Sperm Motility; Spermatozoa; Spironolactone; Testis; Testosterone | 1977 |
Simultaneous automated determination of spironolactone metabolites in serum.
Topics: Autoanalysis; Canrenoic Acid; Canrenone; Humans; Methods; Spectrometry, Fluorescence; Spironolactone; Time Factors | 1977 |
Effects of pretreatment with spironolactone of pharmacokinetics of 4'''-methyldigoxin in man.
Topics: Administration, Oral; Adult; Bile; Canrenoic Acid; Canrenone; Digoxin; Feces; Female; Half-Life; Humans; Injections, Intravenous; Kinetics; Male; Middle Aged; Spironolactone; Tritium | 1976 |
Effects of spironolactone, canrenone and canrenoate-K on cytochrome P450, and 11beta- and 18-hydroxylation in bovine and human adrenal cortical mitochondria.
Topics: Adenoma; Adrenal Cortex; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Animals; Canrenoic Acid; Canrenone; Cattle; Cytochrome P-450 Enzyme System; Humans; Hyperplasia; Mitochondria; Oxidation-Reduction; Pregnadienes; Spectrum Analysis; Spironolactone; Steroid Hydroxylases | 1976 |
Renal clearance of canrenoate in normal man.
Topics: 17-Ketosteroids; Aldosterone; Canrenoic Acid; Canrenone; Humans; Hydroxysteroids; Kidney; Kidney Function Tests; Male; Metabolic Clearance Rate; Pregnadienes; Renin | 1975 |
Rapid effects of mineralocorticoids on sodium-proton exchanger: genomic or nongenomic pathway?
Topics: Aldosterone; Calcium; Canrenoic Acid; Canrenone; Carrier Proteins; Dexamethasone; DNA; Humans; Hydrocortisone; In Vitro Techniques; Kinetics; Leukocytes, Mononuclear; Models, Biological; Potassium; Propionates; Reference Values; Sodium; Sodium-Hydrogen Exchangers | 1991 |
Spironolactone and canrenoate: different antialdosteronic diuretic agents.
Topics: Ascites; Canrenoic Acid; Canrenone; Humans; Liver Cirrhosis; Recurrence; Spironolactone | 1991 |
Aldosterone influences free intracellular calcium in human mononuclear leukocytes in vitro.
Topics: Adolescent; Adult; Aged; Aldosterone; Amiloride; Calcium; Canrenoic Acid; Canrenone; Corticosterone; Cycloheximide; Dactinomycin; Humans; Hydrocortisone; Leukocytes, Mononuclear; Middle Aged | 1990 |
Reversible pharmacokinetic profiles of canrenoic acid and its biotransformed product. Canrenone in the rat.
Topics: Animals; Biotransformation; Canrenoic Acid; Canrenone; Male; Pregnadienes; Rats; Rats, Inbred Strains | 1990 |
Simultaneous quantitative determination of butizide, potassium canrenoate and canrenone in tablets by high-performance liquid chromatography.
Topics: Canrenoic Acid; Canrenone; Chromatography, High Pressure Liquid; Diuretics; Drug Stability; Hydrochlorothiazide; Indicators and Reagents; Pregnadienes; Sodium Chloride Symporter Inhibitors; Spectrophotometry, Ultraviolet; Tablets | 1986 |
Progestogens with antimineralocorticoid activity.
Topics: Adrenalectomy; Aldosterone; Androstadienes; Androstenes; Animals; Canrenoic Acid; Canrenone; Cyproterone; Dose-Response Relationship, Drug; Male; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; Norethindrone; Norgestrel; Norpregnenes; Potassium; Progesterone; Progesterone Congeners; Rats; Rats, Inbred Strains; Sodium; Spironolactone | 1985 |
Use of a simple fluorometric 11-hydroxycorticosteroids assay in the assessment of spironolactone-metabolite level in plasma and urine.
Topics: Canrenoic Acid; Canrenone; Dose-Response Relationship, Drug; Humans; Hydrocortisone; Spironolactone; Time Factors | 1974 |
Canrenone as a partial agonist at the digitalis receptor site of sodium-potassium-activated adenosine triphosphatase.
Topics: 4-Nitrophenylphosphatase; Animals; Canrenoic Acid; Canrenone; Guinea Pigs; In Vitro Techniques; Ouabain; Potassium; Pregnadienes; Protein Binding; Receptors, Drug; Sodium-Potassium-Exchanging ATPase; Spironolactone | 1981 |
Negative inotropic effects of aldosterone antagonists in isolated human and guinea-pig ventricular heart muscle.
Topics: Animals; Canrenoic Acid; Canrenone; Drug Interactions; Guinea Pigs; Heart Ventricles; Humans; Mineralocorticoid Receptor Antagonists; Myocardial Contraction; Ouabain | 1984 |
Clinical pharmacology of diuretics.
Topics: Canrenoic Acid; Canrenone; Diuretics; Ethacrynic Acid; Humans; Hydrochlorothiazide; Intestinal Absorption; Kinetics; Protein Binding; Sodium Chloride Symporter Inhibitors; Spironolactone | 1983 |
Importance of the lactonic ring in the activity of steroidal antialdosterones.
Topics: Adrenalectomy; Animals; Canrenoic Acid; Canrenone; Chemical Phenomena; Chemistry; Lactones; Male; Mineralocorticoid Receptor Antagonists; Potassium; Rats; Sodium; Spironolactone; Steroids | 1980 |
Increase in the basal tone of guinea pig thoracic aorta induced by ouabain is inhibited by spironolactone canrenone and potassium canrenoate.
Topics: Animals; Aorta, Thoracic; Canrenoic Acid; Canrenone; Cardiotonic Agents; Guinea Pigs; In Vitro Techniques; Isotonic Solutions; Muscle, Smooth, Vascular; Ouabain; Potassium; Sodium-Potassium-Exchanging ATPase; Spironolactone; Vasoconstriction | 1996 |
Effect of spironolactone and its metabolites on contractile property of isolated rat aorta rings.
Topics: Animals; Aorta, Thoracic; Calcium Channel Blockers; Canrenoic Acid; Canrenone; In Vitro Techniques; Male; Mineralocorticoid Receptor Antagonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Potassium Channel Blockers; Potassium Chloride; Rats; Rats, Wistar; Spironolactone | 2000 |
Bidirectional (positive/negative) interference of spironolactone, canrenone, and potassium canrenoate on serum digoxin measurement: elimination of interference by measuring free digoxin or using a chemiluminescent assay for digoxin.
Topics: Canrenoic Acid; Canrenone; Cardiotonic Agents; Digoxin; Drug Interactions; Fluorescence Polarization Immunoassay; Humans; Luminescent Measurements; Mineralocorticoid Receptor Antagonists; Reproducibility of Results; Spironolactone | 2002 |
A new turbidometric digoxin immunoassay on the ADVIA 1650 analyzer is free from interference by spironolactone, potassium canrenoate, and their common metabolite canrenone.
Topics: Canrenoic Acid; Canrenone; Cardiotonic Agents; Cross Reactions; Digoxin; Drug Interactions; Fluorescence Polarization Immunoassay; Humans; Spironolactone | 2003 |
Effect of spironolactone, potassium canrenoate and their common metabolite canrenone on serum digoxin measurement by digoxin III, a new digoxin immunoassay.
Topics: Canrenoic Acid; Canrenone; Cross Reactions; Digoxin; Drug Interactions; Humans; Immunoassay; Mineralocorticoid Receptor Antagonists; Spironolactone | 2008 |
Spironolactone and canrenone inhibit UGT2B7-catalyzed human liver and kidney microsomal aldosterone 18beta-glucuronidation: a potential drug interaction.
Topics: Aldosterone; Binding, Competitive; Canrenoic Acid; Canrenone; Drug Interactions; Glucuronosyltransferase; Humans; Hymecromone; In Vitro Techniques; Kidney; Microsomes; Microsomes, Liver; Spironolactone | 2010 |
Abbott ARCHITECT clinical chemistry and immunoassay systems: digoxin assays are free of interferences from spironolactone, potassium canrenoate, and their common metabolite canrenone.
Topics: Anti-Arrhythmia Agents; Canrenoic Acid; Canrenone; Chemistry, Clinical; Cross Reactions; Digoxin; Immunoassay; Mineralocorticoid Receptor Antagonists; Spironolactone | 2011 |
Effect of spironolactone, potassium canrenoate, and their common metabolite canrenone on Dimension Vista Digoxin Assay.
Topics: Biological Assay; Canrenoic Acid; Canrenone; Cardiotonic Agents; Chemistry, Clinical; Cross Reactions; Digoxin; Drug Interactions; Drug Monitoring; Humans; Immunoassay; Mineralocorticoid Receptor Antagonists; Osmolar Concentration; Reagent Kits, Diagnostic; Spironolactone | 2010 |
Clinically insignificant negative interferences of spironolactone, potassium canrenoate, and their common metabolite canrenone in new dimension vista LOCI digoxin immunoassay.
Topics: Canrenoic Acid; Canrenone; Digoxin; Humans; Immunoassay; Luminescent Measurements; Models, Molecular; Spironolactone | 2012 |