cannabidiol and carbitol

cannabidiol has been researched along with carbitol* in 1 studies

Other Studies

1 other study(ies) available for cannabidiol and carbitol

Article	Year
Development of cannabidiol nanoemulsion for direct nose to brain delivery: statistical optimization, Biomedical materials (Bristol, England), 2022, Sep-28, Volume: 17, Issue:6 Cannabidiol (CBD) is a prescribed drug for epilepsy but has low oral bioavailability and gastric instability. Because of the direct link between the nasal cavity and the central nervous system, intranasal administration of CBD as nanoemulsions which are the small sized lipid carriers seem to improve the bioavailability. CBD-nanoemulsions (NEs) were made using Capryol 90, Tween 80, and Transcutol P as oil, surfactant, and co-surfactant, respectively, following aqueous titration approach. Then, using the Box-Behnken design, CBD-NE was statistically optimised for the selection of desirable excipient concentrations in order to create the optimal CBD-NE formulation. As independent variables in the statistical design, Capryol 90 (oil; coded as Topics: Brain; Cannabidiol; Drug Delivery Systems; Emulsions; Ethylene Glycols; Excipients; Lipids; Nanoparticles; Particle Size; Polymers; Polysorbates; Propylene Glycols; Surface-Active Agents	2022

Article

Year

Development of cannabidiol nanoemulsion for direct nose to brain delivery: statistical optimization,

Biomedical materials (Bristol, England), 2022, Sep-28, Volume: 17, Issue:6

Cannabidiol (CBD) is a prescribed drug for epilepsy but has low oral bioavailability and gastric instability. Because of the direct link between the nasal cavity and the central nervous system, intranasal administration of CBD as nanoemulsions which are the small sized lipid carriers seem to improve the bioavailability. CBD-nanoemulsions (NEs) were made using Capryol 90, Tween 80, and Transcutol P as oil, surfactant, and co-surfactant, respectively, following aqueous titration approach. Then, using the Box-Behnken design, CBD-NE was statistically optimised for the selection of desirable excipient concentrations in order to create the optimal CBD-NE formulation. As independent variables in the statistical design, Capryol 90 (oil; coded as

Topics: Brain; Cannabidiol; Drug Delivery Systems; Emulsions; Ethylene Glycols; Excipients; Lipids; Nanoparticles; Particle Size; Polymers; Polysorbates; Propylene Glycols; Surface-Active Agents

2022