canertinib dihydrochloride has been researched along with pf 00299804 in 1 studies
| Studies (canertinib dihydrochloride) | Trials (canertinib dihydrochloride) | Recent Studies (post-2010) (canertinib dihydrochloride) | Studies (pf 00299804) | Trials (pf 00299804) | Recent Studies (post-2010) (pf 00299804) |
|---|---|---|---|---|---|
| 31 | 13 | 6 | 180 | 41 | 172 |
| Protein | Taxonomy | canertinib dihydrochloride (IC50) | pf 00299804 (IC50) |
|---|---|---|---|
| Epidermal growth factor receptor | Homo sapiens (human) | 0.037 | |
| Receptor tyrosine-protein kinase erbB-2 | Homo sapiens (human) | 0.0392 | |
| Tyrosine-protein kinase Lck | Homo sapiens (human) | 0.094 | |
| Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | 0.11 | |
| Receptor tyrosine-protein kinase erbB-3 | Homo sapiens (human) | 0.0006 | |
| Mitogen-activated protein kinase kinase kinase 8 | Homo sapiens (human) | 3.57 | |
| Tyrosine-protein kinase JAK3 | Homo sapiens (human) | 3.57 | |
| Receptor tyrosine-protein kinase erbB-4 | Homo sapiens (human) | 0.0494 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Althaus, IW; Black, SL; Blaser, A; Bridges, A; Denny, WA; Ellis, PA; Ellis, T; Fakhoury, S; Gonzales, AJ; Harvey, PJ; Hook, K; Lee, H; McCarthy, FO; Palmer, BD; Reed, JE; Rivault, F; Schlosser, K; Sexton, K; Smaill, JB; Spicer, JA; Tecle, H; Thompson, AM; Trachet, E; Winters, RT; Zhu, T | 1 |
1 other study(ies) available for canertinib dihydrochloride and pf 00299804
| Article | Year |
|---|---|
Tyrosine Kinase Inhibitors. 20. Optimization of Substituted Quinazoline and Pyrido[3,4-d]pyrimidine Derivatives as Orally Active, Irreversible Inhibitors of the Epidermal Growth Factor Receptor Family.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Dogs; ErbB Receptors; Heterografts; Humans; Injections, Intravenous; Macaca fascicularis; Male; Mice, Nude; Morpholines; Neoplasm Transplantation; Phosphorylation; Pyridines; Pyrimidines; Quinazolines; Quinazolinones; Rats, Sprague-Dawley; Stereoisomerism; Structure-Activity Relationship | 2016 |