Page last updated: 2024-09-04

canertinib dihydrochloride and ekb 569

canertinib dihydrochloride has been researched along with ekb 569 in 2 studies

Compound Research Comparison

Studies (canertinib dihydrochloride)	Trials (canertinib dihydrochloride)	Recent Studies (post-2010) (canertinib dihydrochloride)	Studies (ekb 569)	Trials (ekb 569)	Recent Studies (post-2010) (ekb 569)
31	13	6	68	5	33

Protein Interaction Comparison

Protein	Taxonomy	ekb 569 (IC50)
Epidermal growth factor receptor	Homo sapiens (human)	0.0489
Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)	1.2298
Vascular endothelial growth factor receptor 2	Homo sapiens (human)	3.131
Serine/threonine-protein kinase Nek2	Homo sapiens (human)	0.661

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Russu, WA; Shallal, HM	1
Althaus, IW; Black, SL; Blaser, A; Bridges, A; Denny, WA; Ellis, PA; Ellis, T; Fakhoury, S; Gonzales, AJ; Harvey, PJ; Hook, K; Lee, H; McCarthy, FO; Palmer, BD; Reed, JE; Rivault, F; Schlosser, K; Sexton, K; Smaill, JB; Spicer, JA; Tecle, H; Thompson, AM; Trachet, E; Winters, RT; Zhu, T	1

Other Studies

2 other study(ies) available for canertinib dihydrochloride and ekb 569

Article	Year
Discovery, synthesis, and investigation of the antitumor activity of novel piperazinylpyrimidine derivatives. European journal of medicinal chemistry, 2011, Volume: 46, Issue:6 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Molecular Structure; Piperazines; Protein Kinase Inhibitors; Protein Kinases; Pyrimidines; Stereoisomerism; Structure-Activity Relationship	2011
Tyrosine Kinase Inhibitors. 20. Optimization of Substituted Quinazoline and Pyrido[3,4-d]pyrimidine Derivatives as Orally Active, Irreversible Inhibitors of the Epidermal Growth Factor Receptor Family. Journal of medicinal chemistry, 2016, 09-08, Volume: 59, Issue:17 Topics: Administration, Oral; Animals; Antineoplastic Agents; Dogs; ErbB Receptors; Heterografts; Humans; Injections, Intravenous; Macaca fascicularis; Male; Mice, Nude; Morpholines; Neoplasm Transplantation; Phosphorylation; Pyridines; Pyrimidines; Quinazolines; Quinazolinones; Rats, Sprague-Dawley; Stereoisomerism; Structure-Activity Relationship	2016

Article

Year

Discovery, synthesis, and investigation of the antitumor activity of novel piperazinylpyrimidine derivatives.

European journal of medicinal chemistry, 2011, Volume: 46, Issue:6

Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Molecular Structure; Piperazines; Protein Kinase Inhibitors; Protein Kinases; Pyrimidines; Stereoisomerism; Structure-Activity Relationship

2011

Tyrosine Kinase Inhibitors. 20. Optimization of Substituted Quinazoline and Pyrido[3,4-d]pyrimidine Derivatives as Orally Active, Irreversible Inhibitors of the Epidermal Growth Factor Receptor Family.

Journal of medicinal chemistry, 2016, 09-08, Volume: 59, Issue:17

Topics: Administration, Oral; Animals; Antineoplastic Agents; Dogs; ErbB Receptors; Heterografts; Humans; Injections, Intravenous; Macaca fascicularis; Male; Mice, Nude; Morpholines; Neoplasm Transplantation; Phosphorylation; Pyridines; Pyrimidines; Quinazolines; Quinazolinones; Rats, Sprague-Dawley; Stereoisomerism; Structure-Activity Relationship

2016