Compounds > canertinib
Page last updated: 2024-09-04

canertinib and plx 4720

canertinib has been researched along with plx 4720 in 2 studies

Compound Research Comparison

Studies
(canertinib)		Trials
(canertinib)		Recent Studies (post-2010)
(canertinib)		Studies
(plx 4720)		Trials
(plx 4720)		Recent Studies (post-2010) (plx 4720)
1249651631151

Protein Interaction Comparison

ProteinTaxonomycanertinib (IC50)plx 4720 (IC50)
Chain A, B-Raf proto-oncogene serine/threonine-protein kinaseHomo sapiens (human)0.16
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1Homo sapiens (human)0.16
Chain A, Basic fibroblast growth factor receptor 1Homo sapiens (human)0.16
PirinHomo sapiens (human)0.67
Aurora kinase AHomo sapiens (human)1.8466
Mitogen-activated protein kinase kinase kinase kinase 4Homo sapiens (human)1.8466
RAF proto-oncogene serine/threonine-protein kinaseHomo sapiens (human)0.0065
Macrophage colony-stimulating factor 1 receptorHomo sapiens (human)1.8466
Fibroblast growth factor receptor 1Homo sapiens (human)1.8466
Proto-oncogene tyrosine-protein kinase SrcHomo sapiens (human)1.3575
Serine/threonine-protein kinase B-rafHomo sapiens (human)0.8593
Vascular endothelial growth factor receptor 2Homo sapiens (human)1.3575
Tyrosine-protein kinase CSKHomo sapiens (human)1.8466
Tyrosine-protein kinase FRKHomo sapiens (human)1.3575
Focal adhesion kinase 1Homo sapiens (human)1.8466
Protein-tyrosine kinase 6Homo sapiens (human)1.3575

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ciceri, P; Davis, MI; Herrgard, S; Hocker, M; Hunt, JP; Pallares, G; Treiber, DK; Wodicka, LM; Zarrinkar, PP1
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1

Other Studies

2 other study(ies) available for canertinib and plx 4720

ArticleYear
Comprehensive analysis of kinase inhibitor selectivity.
    Nature biotechnology, 2011, Oct-30, Volume: 29, Issue:11

    Topics: Catalysis; Drug Design; Enzyme Stability; High-Throughput Screening Assays; Humans; Protein Binding; Protein Kinase Inhibitors; Protein Kinases; Proteomics; Signal Transduction; Substrate Specificity

2011
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013