candoxatrilat has been researched along with aldosterone in 4 studies
| Studies (candoxatrilat) | Trials (candoxatrilat) | Recent Studies (post-2010) (candoxatrilat) | Studies (aldosterone) | Trials (aldosterone) | Recent Studies (post-2010) (aldosterone) |
|---|---|---|---|---|---|
| 46 | 10 | 1 | 25,333 | 1,517 | 4,169 |
| Protein | Taxonomy | candoxatrilat (IC50) | aldosterone (IC50) |
|---|---|---|---|
| Mineralocorticoid receptor | Homo sapiens (human) | 0.0048 | |
| Mineralocorticoid receptor | Rattus norvegicus (Norway rat) | 0.043 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Connell, JM; Cussans, NJ; Davidson, G; Dilly, SG; Doyle, J; Jardine, AG; Leckie, BL; Lever, AF; Northridge, D | 1 |
| Cramb, G; Lang, CC; Motwani, JG; Struthers, AD | 1 |
| Cleland, JG; Good, JM; Jackson, N; Oakley, CM; Peters, M; Wilkins, M | 1 |
| Ferro, CJ; Haynes, WG; Spratt, JC; Webb, DJ | 1 |
4 trial(s) available for candoxatrilat and aldosterone
| Article | Year |
|---|---|
The atriopeptidase inhibitor UK 69,578 increases atrial natriuretic factor and causes a natriuresis in normal humans.
Topics: Adult; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Carbamates; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Injections, Intravenous; Kidney; Male; Middle Aged; Natriuresis; Neprilysin; Propionates; Renin; Sodium | 1990 |
Natriuretic response to neutral endopeptidase inhibition is blunted by enalapril in healthy men.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Interactions; Enalapril; Glomerular Filtration Rate; Humans; Male; Natriuresis; Neprilysin; Renal Circulation; Single-Blind Method | 1995 |
Renal response to candoxatrilat in patients with heart failure.
Topics: Aged; Aldosterone; Atrial Natriuretic Factor; Cross-Over Studies; Cyclic GMP; Cyclohexanecarboxylic Acids; Diuresis; Double-Blind Method; Drug Administration Schedule; Electrolytes; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Neprilysin; Renal Circulation; Sodium; Urine; Vasoactive Intestinal Peptide | 1995 |
Inhibition of neutral endopeptidase causes vasoconstriction of human resistance vessels in vivo.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Atrial Natriuretic Factor; Blood Pressure; Coronary Vessels; Cross-Over Studies; Cyclohexanecarboxylic Acids; Enalapril; Endothelin-1; Humans; Hypertension; Injections, Intra-Arterial; Male; Middle Aged; Myocardium; Neprilysin; Peptides, Cyclic; Protease Inhibitors; Renin; Single-Blind Method; Thiorphan; Vasoconstriction | 1998 |