Page last updated: 2024-09-03

candoxatril and thiorphan

candoxatril has been researched along with thiorphan in 3 studies

Compound Research Comparison

Studies
(candoxatril)
Trials
(candoxatril)
Recent Studies (post-2010)
(candoxatril)
Studies
(thiorphan)
Trials
(thiorphan)
Recent Studies (post-2010) (thiorphan)
622956655082

Protein Interaction Comparison

ProteinTaxonomycandoxatril (IC50)thiorphan (IC50)
ThermolysinBacillus thermoproteolyticus9.5
NeprilysinRattus norvegicus (Norway rat)0.0058
NeprilysinOryctolagus cuniculus (rabbit)0.0085
NeprilysinHomo sapiens (human)0.0024
Angiotensin-converting enzyme Homo sapiens (human)0.2281
Angiotensin-converting enzymeOryctolagus cuniculus (rabbit)0.42
NeprilysinSus scrofa (pig)0.0062

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Goto, A; Hayakawa, H; Hirata, Y; Kangawa, K; Kimura, K; Matsuo, H; Minamino, N; Omata, M; Suzuki, E; Suzuki, Y1
Wilkins, MR1
Berezin, AE1

Reviews

2 review(s) available for candoxatril and thiorphan

ArticleYear
Clinical potential of endopeptidase-24.11 inhibitors in cardiovascular disease.
    Biochemical Society transactions, 1993, Volume: 21 ( Pt 3), Issue:3

    Topics: Animals; Antihypertensive Agents; Cardiovascular Diseases; Cyclohexanecarboxylic Acids; Diuretics; Drug Design; Heart Failure; Humans; Hypertension; Indans; Neprilysin; Propionates; Protease Inhibitors; Thiorphan

1993
[The new class of drugs-- metalloprotease inhibitors -- in the treatment of heart failure].
    Klinicheskaia meditsina, 2004, Volume: 82, Issue:5

    Topics: Glycopeptides; Heart Failure; Hemodynamics; Humans; Indans; Metalloproteases; Propionates; Protease Inhibitors; Pyridines; Thiazepines; Thiorphan

2004

Other Studies

1 other study(ies) available for candoxatril and thiorphan

ArticleYear
Mechanisms underlying the augmented responses of deoxycorticosterone acetate-salt hypertensive rats to neutral endopeptidase inhibitors.
    Journal of hypertension, 1994, Volume: 12, Issue:4

    Topics: Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Base Sequence; Blood Pressure; Desoxycorticosterone; Hypertension; Indans; Male; Molecular Sequence Data; Neprilysin; Polysaccharides; Propionates; Rats; Rats, Wistar; Sodium Chloride; Thiorphan

1994