Compounds > candoxatril
Page last updated: 2024-09-03

candoxatril and cyclic gmp

candoxatril has been researched along with cyclic gmp in 5 studies

Compound Research Comparison

Studies
(candoxatril)		Trials
(candoxatril)		Recent Studies (post-2010)
(candoxatril)		Studies
(cyclic gmp)		Trials
(cyclic gmp)		Recent Studies (post-2010) (cyclic gmp)
6229522,3463334,062

Protein Interaction Comparison

ProteinTaxonomycandoxatril (IC50)cyclic gmp (IC50)
Phosphodiesterase Bos taurus (cattle)0.1
cGMP-inhibited 3',5'-cyclic phosphodiesterase BHomo sapiens (human)2.4
cGMP-inhibited 3',5'-cyclic phosphodiesterase AHomo sapiens (human)2.4

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (60.00)18.2507
2000's2 (40.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Buckley, MG; MacGregor, GA; Markandu, ND; Sagnella, GA; Singer, DR1
Espiner, EA; Frampton, C; Ikram, H; Richards, AM; Wittert, G; Yandle, TG1
Barclay, PL; Burnett, JC; Margulies, KB1
Haloui, M; Louedec, L; Messika-Zeitoun, D; Michel, JB; Philippe, M1
Borgeson, DD; Burnett, JC; Cataliotti, A; Luchner, A; Martin, FL; Redfield, MM; Schirger, JA; Stevens, TL1

Trials

2 trial(s) available for candoxatril and cyclic gmp

ArticleYear
Is atrial natriuretic peptide-guanosine 3',5' cyclic monophosphate coupling a determinant of urinary sodium excretion in essential hypertension?
    Journal of hypertension, 1992, Volume: 10, Issue:4

    Topics: Atrial Natriuretic Factor; Cyclic GMP; Female; Humans; Hypertension; Indans; Male; Middle Aged; Natriuresis; Neprilysin; Propionates; Sodium, Dietary

1992
Prolonged inhibition of endopeptidase 24.11 in normal man: renal, endocrine and haemodynamic effects.
    Journal of hypertension, 1991, Volume: 9, Issue:10

    Topics: Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Circadian Rhythm; Creatinine; Cyclic GMP; Double-Blind Method; Endocrine Glands; Hemodynamics; Humans; Indans; Kidney; Natriuresis; Neprilysin; Propionates; Reference Values; Renin

1991

Other Studies

3 other study(ies) available for candoxatril and cyclic gmp

ArticleYear
The role of neutral endopeptidase in dogs with evolving congestive heart failure.
    Circulation, 1995, Apr-01, Volume: 91, Issue:7

    Topics: Animals; Atrial Natriuretic Factor; Cyclic GMP; Dogs; Heart Failure; Hemodynamics; Indans; Kidney; Male; Natriuresis; Neprilysin; Propionates; Sodium; Time Factors

1995
Potentiation of urinary atrial natriuretic peptide interferes with macula densa function.
    Cardiovascular research, 2001, Aug-15, Volume: 51, Issue:3

    Topics: Animals; Atrial Natriuretic Factor; Bumetanide; Chlorides; Cyclic GMP; Diuresis; Epithelial Cells; Indans; Kidney Tubules, Distal; Male; NADPH Dehydrogenase; Neprilysin; Nitric Oxide Synthase; Potassium; Propionates; Proteins; Rats; Rats, Wistar; Renin-Angiotensin System; Sodium; Tuberous Sclerosis Complex 1 Protein; Tumor Suppressor Proteins

2001
Natriuretic and antialdosterone actions of chronic oral NEP inhibition during progressive congestive heart failure.
    Kidney international, 2005, Volume: 67, Issue:5

    Topics: Administration, Oral; Aldosterone; Animals; Atrial Natriuretic Factor; Cyclic GMP; Disease Models, Animal; Dogs; Heart; Heart Failure; Indans; Kidney; Male; Mineralocorticoid Receptor Antagonists; Natriuresis; Neprilysin; Propionates; Protease Inhibitors

2005