Page last updated: 2024-09-03

candoxatril and angiotensin ii

candoxatril has been researched along with angiotensin ii in 7 studies

Compound Research Comparison

Studies (candoxatril)	Trials (candoxatril)	Recent Studies (post-2010) (candoxatril)	Studies (angiotensin ii)	Trials (angiotensin ii)	Recent Studies (post-2010) (angiotensin ii)
62	29	5	38,152	1,089	7,413

Protein Interaction Comparison

Protein	Taxonomy	angiotensin ii (IC50)
Atrial natriuretic peptide receptor 3	Homo sapiens (human)	0.002
Type-1A angiotensin II receptor	Rattus norvegicus (Norway rat)	0.002
Type-1B angiotensin II receptor	Rattus norvegicus (Norway rat)	0.0018
Type-1 angiotensin II receptor	Homo sapiens (human)	0.0055
Type-2 angiotensin II receptor	Rattus norvegicus (Norway rat)	0.004
Type-2 angiotensin II receptor	Homo sapiens (human)	0.0011

Research

Studies (7)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	5 (71.43)	18.2507
2000's	1 (14.29)	29.6817
2010's	1 (14.29)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Espiner, EA; Frampton, C; Ikram, H; Richards, AM; Wittert, GA; Yandle, TG	1
Espiner, EA; Frampton, C; Ikram, H; Richards, AM; Wittert, G; Yandle, TG	1
Connell, JM; Davies, DL; Jardine, AG; McQueen, J; O'Connell, JE	1
Crozier, IG; Espiner, EA; Nicholls, MG; Richards, AM; Yandle, TG	1
Crozier, IG; Espiner, EA; Frampton, C; Ikram, H; Richards, AM; Wittert, GA; Yandle, TG	1
Dendorfer, A; Dominiak, P; Raasch, W	1
Newaz, M; Oyekan, A; Yousefipour, Z	1

Trials

5 trial(s) available for candoxatril and angiotensin ii

Article	Year
Effect of inhibition of endopeptidase 24.11 on responses to angiotensin II in human volunteers. Circulation research, 1992, Volume: 71, Issue:6 Topics: Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Blood Pressure; Double-Blind Method; Humans; Indans; Male; Natriuresis; Neprilysin; Prodrugs; Propionates	1992
Prolonged inhibition of endopeptidase 24.11 in normal man: renal, endocrine and haemodynamic effects. Journal of hypertension, 1991, Volume: 9, Issue:10 Topics: Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Circadian Rhythm; Creatinine; Cyclic GMP; Double-Blind Method; Endocrine Glands; Hemodynamics; Humans; Indans; Kidney; Natriuresis; Neprilysin; Propionates; Reference Values; Renin	1991
Renal and hormonal effects of chronic inhibition of neutral endopeptidase (EC 3.4.24.11) in normal man. Clinical science (London, England : 1979), 1993, Volume: 85, Issue:1 Topics: Adult; Angiotensin II; Atrial Natriuretic Factor; Binding Sites; Blood Platelets; Double-Blind Method; Humans; Indans; Kidney; Male; Middle Aged; Neprilysin; Phenylephrine; Propionates; Reference Values	1993
Plasma brain natriuretic peptide and endopeptidase 24.11 inhibition in hypertension. Hypertension (Dallas, Tex. : 1979), 1993, Volume: 22, Issue:2 Topics: Adult; Aged; Angiotensin II; Atrial Natriuretic Factor; Double-Blind Method; Humans; Hypertension; Indans; Male; Methionine; Middle Aged; Natriuretic Peptide, Brain; Neprilysin; Nerve Tissue Proteins; Posture; Propionates; Time Factors	1993
Chronic inhibition of endopeptidase 24.11 in essential hypertension: evidence for enhanced atrial natriuretic peptide and angiotensin II. Journal of hypertension, 1993, Volume: 11, Issue:4 Topics: Adult; Angiotensin II; Atrial Natriuretic Factor; Blood Pressure; Double-Blind Method; Heart Rate; Humans; Hypertension; Indans; Kidney; Male; Middle Aged; Natriuresis; Neprilysin; Propionates; Time Factors	1993

Other Studies

2 other study(ies) available for candoxatril and angiotensin ii

Article	Year
Angiotensin I-converting enzyme-dependent and neutral endopeptidase-dependent generation and degradation of angiotensin II contrarily modulate noradrenaline release: implications for vasopeptidase-inhibitor therapy? Journal of hypertension, 2005, Volume: 23, Issue:8 Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Dose-Response Relationship, Drug; Indans; Male; Neprilysin; Norepinephrine; Peptidyl-Dipeptidase A; Propionates; Protease Inhibitors; Pyridines; Ramipril; Rats; Rats, Inbred SHR; Thiazepines	2005
Natriuretic and renoprotective effect of chronic oral neutral endopeptidase inhibition in acute renal failure. Renal failure, 2010, Volume: 32, Issue:3 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acute Kidney Injury; Administration, Oral; Angiotensin II; Animals; Antihypertensive Agents; Creatinine; Endothelin-1; Indans; Kidney; Male; Natriuresis; Neprilysin; Nitrates; Propionates; Proteinuria; Rats; Rats, Sprague-Dawley; Thromboxane A2; Vasoconstriction; Vasoconstrictor Agents	2010

Article

Year

Angiotensin I-converting enzyme-dependent and neutral endopeptidase-dependent generation and degradation of angiotensin II contrarily modulate noradrenaline release: implications for vasopeptidase-inhibitor therapy?

Journal of hypertension, 2005, Volume: 23, Issue:8

Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Dose-Response Relationship, Drug; Indans; Male; Neprilysin; Norepinephrine; Peptidyl-Dipeptidase A; Propionates; Protease Inhibitors; Pyridines; Ramipril; Rats; Rats, Inbred SHR; Thiazepines

2005

Natriuretic and renoprotective effect of chronic oral neutral endopeptidase inhibition in acute renal failure.

Renal failure, 2010, Volume: 32, Issue:3

Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acute Kidney Injury; Administration, Oral; Angiotensin II; Animals; Antihypertensive Agents; Creatinine; Endothelin-1; Indans; Kidney; Male; Natriuresis; Neprilysin; Nitrates; Propionates; Proteinuria; Rats; Rats, Sprague-Dawley; Thromboxane A2; Vasoconstriction; Vasoconstrictor Agents

2010