Compounds > candesartan cilexetil

candesartan cilexetil and digoxin

candesartan cilexetil has been researched along with digoxin in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's2 (33.33)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Högemann, A; Jonkman, JH; Lins, R; Sennewald, R; van Heiningen, PN; van Lier, JJ1
Kakizoe, E; Okunishi, H; Shimoura, K; Wang, DQ1
Chatani, F; Kitayoshi, T; Nishimura, S; Watanabe, T; Yamamoto, K1
Kamiyama, E; Mikkaichi, T; Nakai, D; Okazaki, O; Okudaira, N1
Benndorf, RA; Böger, RH; Divac, N; Haefeli, WE; Herzog, M; Sauer, A; Schwedhelm, E; Weiss, J1

Trials

1 trial(s) available for candesartan cilexetil and digoxin

ArticleYear
Pharmacokinetic drug interaction studies with candesartan cilexetil.
    Journal of human hypertension, 1997, Volume: 11 Suppl 2

    Topics: Adolescent; Adult; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Digoxin; Drug Interactions; Female; Glyburide; Humans; Hydrochlorothiazide; Male; Middle Aged; Nifedipine; Tetrazoles; Warfarin

1997

Other Studies

5 other study(ies) available for candesartan cilexetil and digoxin

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Cardiotoxic interaction of metabolites from a prodrug segment cilexetil (cyclohexyloxy-carbonyloxy-ethyl) with digoxin in the canine failing heart.
    Pharmacological research, 2002, Volume: 46, Issue:4

    Topics: Animals; Antihypertensive Agents; Arrhythmias, Cardiac; Benzimidazoles; Biphenyl Compounds; Cardiac Pacing, Artificial; Cardiotonic Agents; Digoxin; Dogs; Dose-Response Relationship, Drug; Heart Failure; Heart Ventricles; Prodrugs; Tetrazoles

2002
Absence of interactive effects of trans-1,2-cyclohexanediol, a major metabolite of the side-chain of candesartan cilexetil, on digoxin-induced arrhythmias in dogs.
    Journal of pharmacological sciences, 2003, Volume: 92, Issue:4

    Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Benzimidazoles; Biphenyl Compounds; Cyclohexanols; Digoxin; Dogs; Drug Interactions; Guinea Pigs; Heart Failure; In Vitro Techniques; Male; Papillary Muscles; Tetrazoles

2003
Interaction of angiotensin II type 1 receptor blockers with P-gp substrates in Caco-2 cells and hMDR1-expressing membranes.
    Life sciences, 2010, Jan-02, Volume: 86, Issue:1-2

    Topics: Adenosine Triphosphatases; Angiotensin II Type 1 Receptor Blockers; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; Benzoates; Biological Transport; Biphenyl Compounds; Caco-2 Cells; Calcium Channel Blockers; Cardiotonic Agents; Cell Membrane; Digoxin; Drug Interactions; Humans; Irbesartan; Losartan; Telmisartan; Tetrazoles; Verapamil

2010
Interaction of angiotensin receptor type 1 blockers with ATP-binding cassette transporters.
    Biopharmaceutics & drug disposition, 2010, Volume: 31, Issue:2-3

    Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Benzimidazoles; Biological Transport; Biphenyl Compounds; Digoxin; Fluoresceins; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Membrane Transport Proteins; Mice; Multidrug Resistance-Associated Protein 2; Olmesartan Medoxomil; Tetrazoles; Thiophenes

2010