candesartan cilexetil and avapro

candesartan cilexetil has been researched along with avapro in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (23.81)18.2507
2000's7 (33.33)29.6817
2010's7 (33.33)24.3611
2020's2 (9.52)2.80

Authors

AuthorsStudies
Goldberg, MR; Greenlee, WJ; Irvin, JD; Prendergast, K; Smith, RD; Timmermans, PB; Wexler, RR1
Schieffer, B; Schmidt, B1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Giridhar, R; Murumkar, P; Naik, P; Yadav, MR1
Gust, R; Obexer, P; Salcher, S; Schoepf, AM1
Bauer, JH; Reams, GP1
Biollaz, J; Brunner, HR; Buclin, T; Burnier, M; Nussberger, J; Waeber, B1
Morsing, P1
Chung, O; Csikós, T; Unger, T1
Bonarjee, VV; Dickstein, K1
Badguet, JP; Mallion, JM1
Burnier, M1
Belz, GG; Breithaupt-Grögler, K; Butzer, R; Fuchs, W; Hausdorf, C; Mang, C1
Bianchetti, MG; Fossali, E; Konrad, M; Rizzi, M; Simonetti, GD; von Vigier, RO1
Bianchetti, MG; Fossali, E; Ghiglia, S; Limoni, C; Meier, CM; Salice, P; Simonetti, GD1
Kamiyama, E; Mikkaichi, T; Nakai, D; Okazaki, O; Okudaira, N1
Benndorf, RA; Böger, RH; Divac, N; Haefeli, WE; Herzog, M; Sauer, A; Schwedhelm, E; Weiss, J1
Boulanger, E; Grossin, N; Wautier, JL; Wautier, MP1
Azegami, T; Hayashi, K; Itoh, H; Nakamura, M; Oguchi, H; Sakamaki, Y; Sasamura, H; Tokuyama, H; Wakino, S1
Anand, IS; Carson, PE; Desai, AS; Granger, CB; Jhund, PS; Komajda, M; Køber, L; Lam, CSP; McKelvie, RS; McMurray, JJV; Pfeffer, MA; Pitt, B; Shen, L; Solomon, SD; Swedberg, K; Tromp, J; Zile, MR1
Abdelsalam, RA; Haddad, GM; Marghany, KA1

Reviews

11 review(s) available for candesartan cilexetil and avapro

ArticleYear
Nonpeptide angiotensin II receptor antagonists: the next generation in antihypertensive therapy.
    Journal of medicinal chemistry, 1996, Feb-02, Volume: 39, Issue:3

    Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Humans; Receptors, Angiotensin; Structure-Activity Relationship

1996
Angiotensin II AT1 receptor antagonists. Clinical implications of active metabolites.
    Journal of medicinal chemistry, 2003, Jun-05, Volume: 46, Issue:12

    Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Growth Hormone; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Models, Molecular; Receptor, Angiotensin, Type 1; Tetrazoles; Thiophenes; Thromboxane A2

2003
Angiotensin II receptor type 1 (AT1) selective nonpeptidic antagonists--a perspective.
    Bioorganic & medicinal chemistry, 2010, Dec-15, Volume: 18, Issue:24

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Antihypertensive Agents; Humans; Losartan

2010
The angiotensin II type 1 receptor antagonists. A new class of antihypertensive drugs.
    Archives of internal medicine, 1995, Jul-10, Volume: 155, Issue:13

    Topics: Acrylates; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Humans; Imidazoles; Irbesartan; Losartan; Pyridines; Quinolines; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan

1995
Pharmacokinetic-pharmacodynamic relationships of three angiotensin II receptor antagonists in normal volunteers.
    Kidney international. Supplement, 1996, Volume: 55

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Humans; Imidazoles; Irbesartan; Losartan; Prodrugs; Reference Values; Tetrazoles

1996
Candesartan: a new-generation angiotensin II AT1 receptor blocker: pharmacology, antihypertensive efficacy, renal function, and renoprotection.
    Journal of the American Society of Nephrology : JASN, 1999, Volume: 10 Suppl 11

    Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Disease Models, Animal; Hemodynamics; Humans; Hypertension; Irbesartan; Kidney; Losartan; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles

1999
Angiotensin II receptor pharmacology and AT1-receptor blockers.
    Journal of human hypertension, 1999, Volume: 13 Suppl 1

    Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Thiophenes

1999
[Use of angiotensin II receptor blockaders in heart failure].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2000, Mar-10, Volume: 120, Issue:7

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Drug Therapy, Combination; Heart Failure; Humans; Irbesartan; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan

2000
Putting the efficacy of candesartan cilexetil into perspective: a review of new comparative data.
    Journal of human hypertension, 2000, Volume: 14 Suppl 2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cattle; Cerebellum; Circadian Rhythm; Female; Heart; Humans; Hypertension; In Vitro Techniques; Irbesartan; Kinetics; Losartan; Male; Middle Aged; Prodrugs; Rabbits; Randomized Controlled Trials as Topic; Receptors, Angiotensin; Renin; Tetrazoles; Time Factors

2000
Angiotensin II type 1 receptor blockers.
    Circulation, 2001, Feb-13, Volume: 103, Issue:6

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Binding, Competitive; Biphenyl Compounds; Blood Pressure; Drug Design; Humans; Irbesartan; Losartan; Peptidyl-Dipeptidase A; Protein Binding; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System; Saralasin; Tetrazoles; Valine; Valsartan

2001
The different isoforms of the receptor for advanced glycation end products are modulated by pharmacological agents.
    Clinical hemorheology and microcirculation, 2010, Volume: 45, Issue:2-4

    Topics: Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Humans; Hypoglycemic Agents; Irbesartan; Protein Isoforms; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Telmisartan; Tetrazoles; Tumor Necrosis Factor-alpha

2010

Trials

4 trial(s) available for candesartan cilexetil and avapro

ArticleYear
The pharmacological potency of various AT(1) antagonists assessed by Schild regression technique in man.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2000, Volume: 1, Issue:4

    Topics: Adult; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Irbesartan; Losartan; Male; Receptor, Angiotensin, Type 1; Reference Values; Tetrazoles; Valine; Valsartan

2000
Candesartan cilexetil in children with hypertension or proteinuria: preliminary data.
    Pediatric nephrology (Berlin, Germany), 2006, Volume: 21, Issue:10

    Topics: Adolescent; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Child; Child, Preschool; Female; Humans; Hypertension; Infant; Irbesartan; Losartan; Male; Proteinuria; Tablets; Tetrazoles

2006
Palatability of angiotensin II antagonists among nephropathic children.
    British journal of clinical pharmacology, 2007, Volume: 63, Issue:5

    Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Child; Child, Preschool; Female; Humans; Irbesartan; Kidney Diseases; Losartan; Male; Patient Compliance; Patient Satisfaction; Smell; Taste; Telmisartan; Tetrazoles; Valine; Valsartan

2007
Age-Related Characteristics and Outcomes of Patients With Heart Failure With Preserved Ejection Fraction.
    Journal of the American College of Cardiology, 2019, 08-06, Volume: 74, Issue:5

    Topics: Age Factors; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Echocardiography; Female; Global Health; Heart Failure; Humans; Irbesartan; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Morbidity; Prognosis; Stroke Volume; Survival Rate; Systole; Tetrazoles; Ventricular Function, Left

2019

Other Studies

6 other study(ies) available for candesartan cilexetil and avapro

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Identification and development of non-cytotoxic cell death modulators: Impact of sartans and derivatives on PPARγ activation and on growth of imatinib-resistant chronic myelogenous leukemia cells.
    European journal of medicinal chemistry, 2020, Jun-01, Volume: 195

    Topics: Animals; Cell Death; Cell Proliferation; Chlorocebus aethiops; COS Cells; Drug Design; Drug Resistance, Neoplasm; Humans; Imatinib Mesylate; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; PPAR gamma; Structure-Activity Relationship; Telmisartan

2020
Interaction of angiotensin II type 1 receptor blockers with P-gp substrates in Caco-2 cells and hMDR1-expressing membranes.
    Life sciences, 2010, Jan-02, Volume: 86, Issue:1-2

    Topics: Adenosine Triphosphatases; Angiotensin II Type 1 Receptor Blockers; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; Benzoates; Biological Transport; Biphenyl Compounds; Caco-2 Cells; Calcium Channel Blockers; Cardiotonic Agents; Cell Membrane; Digoxin; Drug Interactions; Humans; Irbesartan; Losartan; Telmisartan; Tetrazoles; Verapamil

2010
Interaction of angiotensin receptor type 1 blockers with ATP-binding cassette transporters.
    Biopharmaceutics & drug disposition, 2010, Volume: 31, Issue:2-3

    Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Benzimidazoles; Biological Transport; Biphenyl Compounds; Digoxin; Fluoresceins; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Membrane Transport Proteins; Mice; Multidrug Resistance-Associated Protein 2; Olmesartan Medoxomil; Tetrazoles; Thiophenes

2010
Renin-angiotensin blockade resets podocyte epigenome through Kruppel-like Factor 4 and attenuates proteinuria.
    Kidney international, 2015, Volume: 88, Issue:4

    Topics: Albuminuria; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Cell Line; Disease Models, Animal; DNA Methylation; Dose-Response Relationship, Drug; Doxorubicin; Epigenesis, Genetic; Irbesartan; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Male; Membrane Proteins; Mice, Inbred C57BL; Mice, Knockout; Podocytes; Promoter Regions, Genetic; Renal Insufficiency, Chronic; Renin-Angiotensin System; Signal Transduction; Tetrazoles; Time Factors; Transfection

2015
HPLC method transfer study for simultaneous determination of seven angiotensin II receptor blockers.
    Journal of separation science, 2020, Volume: 43, Issue:8

    Topics: Acrylates; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Chlorthalidone; Chromatography, High Pressure Liquid; Hydrochlorothiazide; Imidazoles; Irbesartan; Losartan; Molecular Structure; Software; Tablets; Tetrazoles; Thiophenes; Valsartan

2020