candesartan cilexetil and amlodipine

candesartan cilexetil has been researched along with amlodipine in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (10.00)18.2507
2000's10 (50.00)29.6817
2010's8 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Abe, J; Deguchi, J; Kurokawa, K; Makuuchi, M; Matsumoto, T; Noda, M; Ohno, M; Takuwa, N; Takuwa, Y1
Sever, PS1
Antonios, TF; He, FJ; MacGregor, GA; Viskoper, JR1
Kataoka, H; Kishida, M; Makino, H; Mimura, Y; Ogura, T; Otsuka, F; Takahashi, M; Yamauchi, T1
Chrysant, SG; Harris, SM; Kloner, RA; Leidy, NK; Michelson, EL; Pool, JL; Prasad, R; Weinberger, M; Zyczynski, TM1
Ogihara, T1
Hayashi, K; Homma, K; Kanda, T; Kumagai, H; Saruta, T; Takamatsu, I; Tatematsu, S; Wakino, S; Yoshioka, K1
Imbs, JL; Nisse-Durgeat, S1
Fukui, T1
Ikeda, J; Matsubara, M; Yao, K1
Derosa, G; Fogari, R; Mugellini, A1
Asmar, R; Baguet, JP; Mallion, JM; Nisse-Durgeat, S; Valensi, P1
Miyata, Y; Ogihara, T; Rakugi, H; Sasai, K; Totsuka, N1
Fujimoto, A; Kuwahara, K; Nakagawa, Y; Ueshima, K; Yasuno, S1
Abdel-Khalek, MM; Belal, TS; Daabees, HG; Khamis, MM; Mahrous, MS1
Asai, S; Nakayama, T; Nishida, Y; Susa, N; Takahashi, Y; Yada, Y1
Chang, K; Chung, WB; Hong, SK; Ihm, SH; Kang, MK; Kim, OR; Seung, KB1
Katayama, Y; Nishiyama, Y; Nomura, K; Sunami, E1
Ahn, T; Chae, SC; Cho, EJ; Cho, JH; Choi, JY; Chung, WB; Hong, TJ; Ihm, SH; Jeon, HK; Jeong, MH; Kim, CJ; Kim, WS; Kim, YK; Lee, HY; Lee, JH; Nam, CW; Park, JI; Park, SM; Shin, ES; Sohn, IS; Yang, TH; Yoon, JH; Youn, HJ1

Reviews

2 review(s) available for candesartan cilexetil and amlodipine

ArticleYear
[CASE-J].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64 Suppl 6

    Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Cardiovascular Diseases; Death, Sudden, Cardiac; Endpoint Determination; Follow-Up Studies; Humans; Hypertension; Japan; Middle Aged; Prognosis; Prospective Studies; Randomized Controlled Trials as Topic; Risk; Single-Blind Method; Stroke; Tetrazoles

2006
Fixed-dose combination therapy of candesartan cilexetil and amlodipine besilate for the treatment of hypertension in Japan.
    Expert review of cardiovascular therapy, 2012, Volume: 10, Issue:5

    Topics: Administration, Oral; Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Drug Combinations; Humans; Hypertension; Japan; Tetrazoles

2012

Trials

8 trial(s) available for candesartan cilexetil and amlodipine

ArticleYear
Efficacy of candesartan cilexetil alone or in combination with amlodipine and hydrochlorothiazide in moderate-to-severe hypertension. UK and Israel Candesartan Investigators.
    Hypertension (Dallas, Tex. : 1979), 2000, Volume: 36, Issue:3

    Topics: Aldosterone; Amlodipine; Analysis of Variance; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Israel; Male; Middle Aged; Renin; Single-Blind Method; Tetrazoles; United Kingdom

2000
Comparative effects of candesartan cilexetil and amlodipine in patients with mild systemic hypertension. Comparison of Candesartan and Amlodipine for Safety, Tolerability and Efficacy (CASTLE) Study Investigators.
    The American journal of cardiology, 2001, Mar-15, Volume: 87, Issue:6

    Topics: Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Edema; Female; Humans; Hypertension; Male; Middle Aged; Patient Satisfaction; Prodrugs; Prospective Studies; Tetrazoles; Treatment Outcome

2001
Beneficial action of candesartan cilexetil plus amlodipine or ACE inhibitors in chronic nondiabetic renal disease.
    Journal of human hypertension, 2004, Volume: 18, Issue:12

    Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Chronic Disease; Drug Therapy, Combination; Humans; Kidney Diseases; Middle Aged; Proteinuria; Tetrazoles; Treatment Outcome

2004
Efficacy and tolerability of candesartan cilexetil vs. amlodipine as assessed by home blood pressure in hypertensive patients.
    International journal of clinical practice, 2005, Volume: 59, Issue:1

    Topics: Adolescent; Adult; Aged; Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Patient Compliance; Tetrazoles; Treatment Outcome

2005
Efficacy and tolerability of candesartan cilexetil/hydrochlorothiazide and amlodipine in patients with poorly controlled mild-to-moderate essential hypertension.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2007, Volume: 8, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Diuretics; Double-Blind Method; Drug Therapy, Combination; Edema; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Severity of Illness Index; Tetrazoles; Treatment Outcome

2007
Effects of candesartan cilexetil on carotid remodeling in hypertensive diabetic patients: the MITEC study.
    Vascular health and risk management, 2009, Volume: 5, Issue:1

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Carotid Artery Diseases; Carotid Artery, Common; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Disease Progression; Diuretics; Double-Blind Method; Female; France; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Time Factors; Treatment Outcome; Tunica Intima; Tunica Media; Ultrasonography

2009
Evaluation of the efficacy and tolerability of combination therapy with candesartan cilexetil and amlodipine besilate compared with candesartan cilexetil monotherapy and amlodipine besilate monotherapy in Japanese patients with mild-to-moderate essential
    Clinical therapeutics, 2012, Volume: 34, Issue:4

    Topics: Aged; Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Japan; Male; Middle Aged; Placebos; Tetrazoles; Treatment Outcome

2012
Efficacy and Tolerability of Combination Therapy Versus Monotherapy with Candesartan and/or Amlodipine for Dose Finding in Essential Hypertension: A Phase II Multicenter, Randomized, Double-blind Clinical Trial.
    Clinical therapeutics, 2017, Volume: 39, Issue:8

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Essential Hypertension; Female; Humans; Male; Middle Aged; Tetrazoles; Treatment Outcome

2017

Other Studies

10 other study(ies) available for candesartan cilexetil and amlodipine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Stimulated activation of platelet-derived growth factor receptor in vivo in balloon-injured arteries: a link between angiotensin II and intimal thickening.
    Circulation, 1997, Sep-16, Volume: 96, Issue:6

    Topics: Amlodipine; Angioplasty, Balloon; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Carotid Artery Injuries; Carotid Artery, Common; ErbB Receptors; Insulin Receptor Substrate Proteins; Male; Phosphoproteins; Phosphorylation; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Platelet-Derived Growth Factor alpha; Receptor, Platelet-Derived Growth Factor beta; Receptors, Angiotensin; Receptors, Platelet-Derived Growth Factor; Tetrazoles; Tunica Intima; Tyrosine

1997
Key features of candesartan cilexetil and a comparison with other angiotensin II receptor antagonists.
    Journal of human hypertension, 1999, Volume: 13 Suppl 1

    Topics: Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Delayed-Action Preparations; Diuretics; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Losartan; Renin-Angiotensin System; Retrospective Studies; Sodium Chloride Symporter Inhibitors; Tetrazoles; Treatment Outcome

1999
Differential effect of chronic inhibition of calcium channel and angiotensin II type 1-receptor on aldosterone synthesis in spontaneously hypertensive rats.
    The Journal of steroid biochemistry and molecular biology, 2000, Volume: 74, Issue:3

    Topics: Adrenal Cortex; Aldosterone; Amlodipine; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Chemical Analysis; Blood Pressure; Body Weight; Calcium Channel Blockers; Calcium Channels; Cholesterol Side-Chain Cleavage Enzyme; Cytochrome P-450 CYP11B2; Heart Rate; Immunochemistry; Male; Organ Size; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium; Tetrazoles; Zona Glomerulosa

2000
[A megatrial of ARB in Japan--CASE-J].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Humans; Hypertension; Japan; Middle Aged; Randomized Controlled Trials as Topic; Tetrazoles

2002
Effects of benidipine, a long-lasting dihydropyridine-Ca2+ channel blocker, on cerebral blood flow autoregulation in spontaneously hypertensive rats.
    Biological & pharmaceutical bulletin, 2006, Volume: 29, Issue:11

    Topics: Administration, Oral; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blood Flow Velocity; Blood Gas Analysis; Blood Pressure; Calcium Channel Blockers; Carbon Dioxide; Cerebral Cortex; Dihydropyridines; Hypertension; Male; Oxygen; Rats; Rats, Inbred SHR; Rats, Wistar; Species Specificity; Tetrazoles; Ultrasonography, Doppler, Pulsed; Vascular Resistance

2006
Validated spectrofluorimetric determination of two pharmaceutical antihypertensive mixtures containing amlodipine besylate together with either candesartan cilexetil or telmisartan.
    Luminescence : the journal of biological and chemical luminescence, 2014, Volume: 29, Issue:7

    Topics: Amlodipine; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Chemistry, Pharmaceutical; Molecular Structure; Spectrometry, Fluorescence; Telmisartan; Tetrazoles

2014
Comparative effect of fixed-dose combination tablets of candesartan cilexetil/amlodipine versus olmesartan medoxomil/azelnidipine on laboratory parameters in patients with hypertension: a retrospective cohort study.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2016, Volume: 38, Issue:2

    Topics: Aged; Alanine Transaminase; Amlodipine; Antihypertensive Agents; Aspartate Aminotransferases; Azetidinecarboxylic Acid; Benzimidazoles; Biphenyl Compounds; Blood Urea Nitrogen; Cohort Studies; Creatinine; Dihydropyridines; Drug Combinations; Female; Glomerular Filtration Rate; Humans; Hypertension; Male; Middle Aged; Olmesartan Medoxomil; Potassium; Propensity Score; Retrospective Studies; Sodium; Tetrazoles; Uric Acid

2016
Effects of candesartan cilexetil and amlodipine orotate on receptor for advanced glycation end products expression in the aortic wall of Otsuka Long-Evans Tokushima Fatty (OETFF) type 2 diabetic rats.
    Archives of pharmacal research, 2016, Volume: 39, Issue:4

    Topics: Amlodipine; Animals; Aorta; Benzimidazoles; Biphenyl Compounds; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Humans; MAP Kinase Signaling System; Rats, Inbred Strains; Receptor for Advanced Glycation End Products; Tetrazoles

2016
Effects of Candesartan Cilexetil Compared with Amlodipine on Serum Asymmetric Dimethylarginine Levels in the Chronic Stage of Cerebral Infarction: A Preliminary Study.
    Journal of Nippon Medical School = Nippon Ika Daigaku zasshi, 2016, Volume: 83, Issue:6

    Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Arginine; Benzimidazoles; Biomarkers; Biphenyl Compounds; Cerebral Infarction; Chronic Disease; Female; Humans; Hypertension; Male; Tetrazoles

2016