candesartan has been researched along with transforming growth factor beta in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (8.00) | 18.2507 |
| 2000's | 16 (64.00) | 29.6817 |
| 2010's | 5 (20.00) | 24.3611 |
| 2020's | 2 (8.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kawachi, H; Kimura, H; Nakamura, T; Obata, J; Ohno, S; Shimizu, F; Yoshida, Y | 1 |
| Fujita, T; Ishigami, T; Iwamoto, T; Kihara, M; Kobayashi, S; Toya, Y; Umemura, S; Yabana, M | 1 |
| Chatziantoniou, C; Dussaule, JC; Fakhouri, F; Tharaux, PL | 1 |
| Guo, DF; Inagami, T; Kimura, H; Naito, A; Nakamura, T; Obata, J; Shimizu, F; Takano, H; Yoshida, Y | 1 |
| Brenner, BM; Chertow, GM; Gurnani, A; Jiang, T; Mackenzie, HS; Rennke, HG; Shahsafaei, A; Taal, MW; Troy, JL | 1 |
| Fukui, H; Ikenaka, Y; Kuriyama, S; Nakatani, T; Noguchi, R; Tsujinoue, H; Yoshii, J; Yoshiji, H | 1 |
| Fusshöller, A; Grabensee, B; Hermsen, D; Hetzel, GR; Hohlfeld, T; Ozcan, F; Plum, J; Rettich, A | 1 |
| Ichihara, S; Iwase, M; Izawa, H; Nagasaka, T; Nagata, K; Nakashima, N; Obata, K; Odashima, M; Somura, F; Yamada, Y; Yokota, M | 1 |
| Ando, T; Itoh, M; Joh, T; Kuno, A; Masuda, K; Nakamura, S; Nakazawa, T; Nomura, T; Ogawa, K; Ohara, H; Sano, H; Sogawa, M; Yamada, T | 1 |
| Hong, SB; Kim, ES; Kim, KA; Kim, MJ; Lee, SW; Song, JH; Suh, JH | 1 |
| de Boer, RA; de Borst, MH; Huitema, S; Navis, G; van Gilst, WH; van Goor, H; Vis, LM | 1 |
| Imaizumi, T; Kai, H; Kuwahara, F; Tokuda, K | 1 |
| Imamura, M; Itoh, H; Nie, L; Ueno, H | 1 |
| Cha, SH; Kim, MJ; Lee, HJ; Lee, SW; Park, GH; Song, JH | 1 |
| Ahn, YB; Cha, BY; Hong, OK; Jeong, IK; Kim, JW; Kim, MJ; Ko, SH; Son, HY; Song, KH; Yoon, KH | 1 |
| Hamaguchi, S; Ide, T; Inoue, N; Kinugawa, S; Matsushima, S; Ohta, Y; Sunagawa, K; Tsutsui, H; Yokota, T | 1 |
| Baker, KM; Kumar, R; Singh, VP | 1 |
| Anegawa, T; Hirooka, Y; Ikeda, A; Imaizumi, T; Kai, H; Kajimoto, H; Kato, S; Koga, M; Kudo, H; Mifune, H; Mori, T; Takayama, N; Yasuoka, S | 1 |
| Higashi, K; Hyodo, T; Kumagai, H; Kushiyama, T; Miura, S; Oda, T; Sakurai, Y; Suzuki, S; Yamada, M | 1 |
| Agrawal, AN; Axtell, R; Ding, Z; Ho, PP; Lanz, TV; Luo, J; Platten, M; Srinagesh, H; Steinman, L; Wyss-Coray, T; Zhang, H | 1 |
| Akanae, W; Nonomura, N; Okuyama, A; Tsujihata, M; Yoshioka, I | 1 |
| Abbas, H; Ali, R; Geirsson, A; Hashim, S; Li, W; Sanchez, JA; Singh, M; Tellides, G | 1 |
| El-Moselhy, MA; Hofni, A; Khalifa, MM; Taye, A | 1 |
| AlQudah, M; Czubryt, MP; Hale, TM | 1 |
| Ando, S; Fujita, N; Fukunaga, M; Hasegawa, M; Hatano, Y; Hirokawa, S; Igarashi, H; Ihara, M; Kakita, A; Kametani, F; Kanazawa, M; Kato, T; Kawashima, Y; Kawata, H; Koyama, A; Manabe, RI; Matsumoto, M; Murayama, S; Nishizawa, M; Nozaki, H; Onodera, O; Saito, R; Saito, S; Sato, T; Sekine, Y; Sugai, A; Sugie, A; Toyoshima, Y; Tsuji, S; Uemura, M | 1 |
1 review(s) available for candesartan and transforming growth factor beta
| Article | Year |
|---|---|
Targeting the renin-angiotensin-aldosterone system in fibrosis.
Topics: Amides; Angiotensins; Animals; Benzimidazoles; Biphenyl Compounds; Extracellular Matrix; Extracellular Matrix Proteins; Fibroblasts; Fibrosis; Fumarates; Gene Expression Regulation; Humans; Kidney; Liver; Molecular Targeted Therapy; Myocardium; Pyridones; Renin-Angiotensin System; Signal Transduction; Skin; Tetrazoles; Transforming Growth Factor beta | 2020 |
2 trial(s) available for candesartan and transforming growth factor beta
| Article | Year |
|---|---|
The effects of dual blockade of the renin-angiotensin system on urinary protein and transforming growth factor-beta excretion in 2 groups of patients with IgA and diabetic nephropathy.
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Cross-Over Studies; Diabetic Nephropathies; Female; Glomerulonephritis, IGA; Humans; Male; Middle Aged; Prospective Studies; Proteinuria; Ramipril; Renin-Angiotensin System; Tetrazoles; Transforming Growth Factor beta | 2003 |
Effect of low-dose dual blockade of renin-angiotensin system on urinary TGF-beta in type 2 diabetic patients with advanced kidney disease.
Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biomarkers; Biphenyl Compounds; Creatinine; Cross-Over Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Humans; Male; Middle Aged; Prospective Studies; Ramipril; Renin-Angiotensin System; Tetrazoles; Transforming Growth Factor beta; Treatment Outcome | 2006 |
22 other study(ies) available for candesartan and transforming growth factor beta
| Article | Year |
|---|---|
Blocking angiotensin II ameliorates proteinuria and glomerular lesions in progressive mesangioproliferative glomerulonephritis.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Bradykinin; Bradykinin Receptor Antagonists; Cilazapril; Collagen; Disease Models, Animal; Glomerulonephritis, Membranoproliferative; Hydralazine; Kidney Failure, Chronic; Male; Proteinuria; Rats; Rats, Wistar; Renal Circulation; Renin-Angiotensin System; Tetrazoles; Transforming Growth Factor beta | 1999 |
Angiotensin II inhibits interleukin-1 beta-induced nitric oxide production in cultured rat mesangial cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antibodies; Benzimidazoles; Biphenyl Compounds; Blotting, Northern; Cells, Cultured; Gene Expression; Glomerular Mesangium; Imidazoles; Interleukin-1; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetrazoles; Transforming Growth Factor beta | 1999 |
Angiotensin II activates collagen I gene through a mechanism involving the MAP/ER kinase pathway.
Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Benzimidazoles; Biphenyl Compounds; Collagen; Decorin; Enzyme Activation; Enzyme Inhibitors; Extracellular Matrix Proteins; Flavonoids; Gene Expression Regulation, Enzymologic; Genes, fos; Genetic Markers; Humans; Imidazoles; Kidney; Luciferases; Male; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Proteoglycans; Proto-Oncogene Mas; Pyridines; Tetrazoles; Transcriptional Activation; Transforming Growth Factor beta | 2000 |
Increased gene expression of components of the renin-angiotensin system in glomeruli of genetically hypertensive rats.
Topics: Albuminuria; Angiotensin II; Angiotensinogen; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blotting, Northern; Fibronectins; Gene Expression; Glomerulosclerosis, Focal Segmental; Hydralazine; Hypertension, Renal; Kidney Glomerulus; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Ribonucleases; RNA, Messenger; Tetrazoles; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2000 |
Mechanisms underlying renoprotection during renin-angiotensin system blockade.
Topics: Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Chemokine CCL2; Enalapril; Endothelin-1; Interleukin-1; Kidney Cortex; Kidney Failure, Chronic; Male; Nephrectomy; Proteinuria; Rats; Rats, Wistar; Renin-Angiotensin System; RNA, Messenger; Tetrazoles; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2001 |
Angiotensin-II type 1 receptor interaction is a major regulator for liver fibrosis development in rats.
Topics: Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Endothelial Growth Factors; Immunohistochemistry; Liver Cirrhosis, Experimental; Lymphokines; Male; Perindopril; Rats; Rats, Inbred F344; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System; RNA, Messenger; Tetrazoles; Transforming Growth Factor beta; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2001 |
Effects of candesartan and perindopril on renal function, TGF-beta1 plasma levels and excretion of prostaglandins in stable renal allograft recipients.
Topics: Adult; Aged; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Creatinine; Dose-Response Relationship, Drug; Follow-Up Studies; Humans; Kidney; Kidney Transplantation; Middle Aged; Perindopril; Prostaglandins; Tetrazoles; Transforming Growth Factor beta; Transforming Growth Factor beta1; Treatment Outcome | 2002 |
AT1 receptor blockade reduces cardiac calcineurin activity in hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcineurin; Cardiomegaly; Echocardiography; Fibrosis; Gene Expression Regulation; Hypertension; Male; Myocardium; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; RNA, Messenger; Stress, Mechanical; Tacrolimus; Tetrazoles; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2002 |
Candesartan, an angiotensin II receptor antagonist, suppresses pancreatic inflammation and fibrosis in rats.
Topics: Actins; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Body Weight; Fibrosis; Hydroxyproline; Immunohistochemistry; Inflammation; Male; Muscle, Smooth; Organ Size; Pancreatitis; Peroxidase; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Tetrazoles; Transforming Growth Factor beta | 2003 |
Specific MAP-kinase blockade protects against renal damage in homozygous TGR(mRen2)27 rats.
Topics: Actins; Aldosterone; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Genetically Modified; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Desmin; Enzyme Inhibitors; Glomerular Mesangium; Homozygote; Imidazoles; Kidney Diseases; Male; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Pyrimidines; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger; Tetrazoles; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tyrphostins | 2003 |
Sub-depressor dose of angiotensin type-1 receptor blocker inhibits transforming growth factor-beta-mediated perivascular fibrosis in hypertensive rat hearts.
Topics: Administration, Oral; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Benzimidazoles; Biphenyl Compounds; Collagen; Constriction; Disease Models, Animal; Dose-Response Relationship, Drug; Endomyocardial Fibrosis; Fibroblasts; Hypertension; Male; Myocytes, Cardiac; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Tetrazoles; Time Factors; Transforming Growth Factor beta; Ventricular Remodeling | 2003 |
Pitavastatin enhances the anti-fibrogenesis effects of candesartan, an angiotensin II receptor blocker, on CCl4-induced liver fibrosis in rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Carbon Tetrachloride; Depression, Chemical; Drug Synergism; Drug Therapy, Combination; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Liver Cirrhosis; Male; Quinolines; Rats; Rats, Sprague-Dawley; Tetrazoles; Transforming Growth Factor beta | 2004 |
High glucose increases extracellular matrix production in pancreatic stellate cells by activating the renin-angiotensin system.
Topics: Angiotensin I; Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Collagen; Connective Tissue Growth Factor; Dose-Response Relationship, Drug; Extracellular Matrix; Extracellular Matrix Proteins; Fibronectins; Fibrosis; Glucose; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Male; Pancreas; Pancreatitis; Ramipril; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Tetrazoles; Transforming Growth Factor beta | 2006 |
Angiotensin II type 1 receptor blocker attenuates myocardial remodeling and preserves diastolic function in diabetic heart.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Benzimidazoles; Biphenyl Compounds; Blood Glucose; Blood Pressure; Body Weight; Cells, Cultured; Connective Tissue Growth Factor; Diabetes Complications; Diabetes Mellitus, Experimental; Diastole; Echocardiography; Fibroblasts; Heart Failure; Heart Rate; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Lipid Peroxidation; Male; Matrix Metalloproteinases; Mice; Mice, Inbred Strains; Myoblasts, Cardiac; Tetrazoles; Transforming Growth Factor beta; Ventricular Function, Left; Ventricular Remodeling | 2007 |
Activation of the intracellular renin-angiotensin system in cardiac fibroblasts by high glucose: role in extracellular matrix production.
Topics: Adrenergic beta-Agonists; Amides; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Benzazepines; Benzimidazoles; Biphenyl Compounds; Blotting, Western; Cells, Cultured; Collagen Type I; Dose-Response Relationship, Drug; Extracellular Matrix; Fibroblasts; Fumarates; Glucose; Heart Ventricles; Isoproterenol; Microscopy, Confocal; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; Tetrazoles; Time Factors; Transforming Growth Factor beta; Up-Regulation | 2008 |
Exaggerated blood pressure variability superimposed on hypertension aggravates cardiac remodeling in rats via angiotensin II system-mediated chronic inflammation.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Chemokine CCL2; Chronic Disease; Disease Models, Animal; Heart Diseases; Heart Ventricles; Hypertension; Hypertrophy; Inflammation; Macrophages; Male; Myocytes, Cardiac; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles; Transforming Growth Factor beta; Ventricular Remodeling | 2009 |
Additive antifibrotic effects of pioglitazone and candesartan on experimental renal fibrosis in mice.
Topics: Adiponectin; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biomarkers; Biphenyl Compounds; Chemokine CCL2; Collagen Type I; Collagen Type III; Disease Models, Animal; Drug Therapy, Combination; Fibrosis; Kidney; Kidney Diseases; Macrophages; Male; Mice; Mice, Inbred C57BL; Pioglitazone; Plasminogen Activator Inhibitor 1; PPAR gamma; RNA, Messenger; Severity of Illness Index; Tetrazoles; Thiazolidinediones; Transforming Growth Factor beta; Ureteral Obstruction | 2010 |
Angiotensin II sustains brain inflammation in mice via TGF-beta.
Topics: Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Chronic Disease; Encephalomyelitis, Autoimmune, Experimental; Female; Mice; Mice, Inbred C57BL; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Signal Transduction; Tetrazoles; Thrombospondin 1; Transforming Growth Factor beta | 2010 |
Angiotensin type-1 receptor blocker candesartan inhibits calcium oxalate crystal deposition in ethylene glycol-treated rat kidneys.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Calcium Oxalate; Deoxyguanosine; Disease Models, Animal; In Vitro Techniques; Kidney Calculi; Kidney Cortex; Male; NADPH Oxidases; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Tetrazoles; Transforming Growth Factor beta | 2011 |
Modulation of transforming growth factor-β signaling and extracellular matrix production in myxomatous mitral valves by angiotensin II receptor blockers.
Topics: Angiotensin Receptor Antagonists; Benzimidazoles; Benzoates; Biphenyl Compounds; Cells, Cultured; Collagen; Elastic Tissue; Extracellular Matrix Proteins; Fibrosis; Gene Expression Regulation; Genetic Diseases, X-Linked; Heart Defects, Congenital; Humans; Losartan; Mitral Valve Insufficiency; Mitral Valve Prolapse; Myxoma; Polymerase Chain Reaction; Signal Transduction; Smad2 Protein; Smad3 Protein; Telmisartan; Tetrazoles; Transforming Growth Factor beta; Vimentin | 2012 |
Combination therapy with spironolactone and candesartan protects against streptozotocin-induced diabetic nephropathy in rats.
Topics: Animals; Antioxidants; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cyclooxygenase 2; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drug Therapy, Combination; Inflammation; Kidney; Male; Malondialdehyde; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Protective Agents; Rats; Rats, Wistar; Spironolactone; Streptozocin; Superoxides; Tetrazoles; Transforming Growth Factor beta | 2014 |
Candesartan prevents arteriopathy progression in cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy model.
Topics: ADAMTS Proteins; Alopecia; Animals; Benzimidazoles; Biphenyl Compounds; Cerebral Infarction; Cerebrovascular Circulation; Disease Progression; Extracellular Matrix Proteins; High-Temperature Requirement A Serine Peptidase 1; Latent TGF-beta Binding Proteins; Leukoencephalopathies; Mice; Mice, Inbred C57BL; Recombinant Proteins; Spinal Diseases; Tetrazoles; Transforming Growth Factor beta | 2021 |