candesartan and pioglitazone

candesartan has been researched along with pioglitazone in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (45.00)29.6817
2010's10 (50.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Gust, R; Obexer, P; Salcher, S; Schoepf, AM1
Benigni, A; Campana, M; Corna, D; Gagliardini, E; Garofano, E; Ito, T; Remuzzi, G; Rottoli, D; Tomasoni, S; Zanchi, C; Zoja, C1
Miura, S; Oda, T; Omasu, F; Sakurai, Y; Yamada, M; Yamakami, K; Yoshizawa, N1
Dong, YF; Kataoka, K; Kim-Mitsuyama, S; Matsuba, S; Nakamura, T; Ogawa, H; Tokutomi, Y; Yamamoto, E; Yamashita, T1
Harata, S; Inden, Y; Kitamura, K; Murohara, T; Nattel, S; Shimano, M; Tsuji, Y; Uchikawa, T1
Tsai, CT; Wilson, LD1
Mano, R; Nakamoto, M; Ohya, Y; Sakima, A; Shinzato, T; Takishita, S; Yamazato, M1
Kintscher, U; Krikov, M; Müller, S; Schefe, JH; Schmerbach, K; Thoene-Reineke, C; Unger, T; Villringer, A1
Koh, KK; Quon, MJ1
Haruna, Y; Kashihara, N; Kobayashi, S; Komai, N; Namikoshi, T; Sasaki, T; Satoh, M; Tomita, N1
Dong, YF; Fukuda, M; Kataoka, K; Kim-Mitsuyama, S; Nakamura, T; Nako, H; Ogawa, H; Tokutomi, Y1
Higashi, K; Hyodo, T; Kumagai, H; Kushiyama, T; Miura, S; Oda, T; Sakurai, Y; Suzuki, S; Yamada, M1
Daida, H; Dohi, T; Iesaki, T; Kasai, T; Kubota, N; Miyauchi, K; Ogita, M; Tsuboi, S; Tsuruta, R; Yokoyama, T1
Erdogdu, O; Eriksson, L; Nyström, T; Sjöholm, Å; Zhang, Q1
Atkinson, J; Capdeville-Atkinson, C; Dupuis, F; Foulquier, S; Gatè, KM; Lartaud, I; Leroy, P; Liminana, P; Perrin-Sarrado, C1
Hayashi, T; Isaka, T; Iuchi, H; Kayama, Y; Ohashi, K; Sakamoto, M; Sakamoto, N; Suzuki, H; Tojo, K; Utsunomiya, K; Yoshimura, M1

Reviews

1 review(s) available for candesartan and pioglitazone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

19 other study(ies) available for candesartan and pioglitazone

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Identification and development of non-cytotoxic cell death modulators: Impact of sartans and derivatives on PPARγ activation and on growth of imatinib-resistant chronic myelogenous leukemia cells.
    European journal of medicinal chemistry, 2020, Jun-01, Volume: 195

    Topics: Animals; Cell Death; Cell Proliferation; Chlorocebus aethiops; COS Cells; Drug Design; Drug Resistance, Neoplasm; Humans; Imatinib Mesylate; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; PPAR gamma; Structure-Activity Relationship; Telmisartan

2020
Transcriptional regulation of nephrin gene by peroxisome proliferator-activated receptor-gamma agonist: molecular mechanism of the antiproteinuric effect of pioglitazone.
    Journal of the American Society of Nephrology : JASN, 2006, Volume: 17, Issue:6

    Topics: Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Gene Expression Regulation; Humans; Hypoglycemic Agents; Kidney Diseases; Male; Membrane Proteins; Pioglitazone; PPAR gamma; Proteinuria; Rats; Rats, Sprague-Dawley; Tetrazoles; Thiazolidinediones; Transcription, Genetic

2006
Effects of pioglitazone and candesartan on renal fibrosis and the intrarenal plasmin cascade in spontaneously hypercholesterolemic rats.
    American journal of physiology. Renal physiology, 2007, Volume: 293, Issue:4

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Disease Models, Animal; Fibrinolysin; Fibrosis; Hypercholesterolemia; Hypoglycemic Agents; Kidney; Macrophages; Male; Pioglitazone; Plasminogen Activator Inhibitor 1; Proteinuria; Random Allocation; Rats; Rats, Mutant Strains; Tetrazoles; Thiazolidinediones

2007
Beneficial effects of pioglitazone on hypertensive cardiovascular injury are enhanced by combination with candesartan.
    Hypertension (Dallas, Tex. : 1979), 2008, Volume: 51, Issue:2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blood Vessels; Cardiomegaly; Cardiovascular Diseases; Drug Combinations; Drug Synergism; Endothelium, Vascular; Genetic Predisposition to Disease; Hypertension; Male; Myocardium; NADPH Oxidase 1; NADPH Oxidases; Nitric Oxide Synthase Type III; Pioglitazone; PPAR gamma; rac1 GTP-Binding Protein; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Stroke; Superoxides; Tetrazoles; Thiazolidinediones; Ventricular Remodeling

2008
Pioglitazone, a peroxisome proliferator-activated receptor-gamma activator, attenuates atrial fibrosis and atrial fibrillation promotion in rabbits with congestive heart failure.
    Heart rhythm, 2008, Volume: 5, Issue:3

    Topics: Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Animals; Atrial Fibrillation; Benzimidazoles; Biphenyl Compounds; Blotting, Western; Disease Models, Animal; Electrophysiologic Techniques, Cardiac; Fibrosis; Heart Failure; Hypoglycemic Agents; Male; Pioglitazone; Rabbits; Tetrazoles; Thiazolidinediones

2008
Heart failure-related atrial fibrillation: a new model for a new prevention strategy?
    Heart rhythm, 2008, Volume: 5, Issue:3

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Atrial Fibrillation; Benzimidazoles; Biphenyl Compounds; Blotting, Western; Disease Models, Animal; Electrophysiologic Techniques, Cardiac; Fibrosis; Heart Failure; Hypoglycemic Agents; Male; Pioglitazone; Rabbits; Tetrazoles; Thiazolidinediones

2008
Pioglitazone, a thiazolidinedione derivative, attenuates left ventricular hypertrophy and fibrosis in salt-sensitive hypertension.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2008, Volume: 31, Issue:2

    Topics: Animals; Benzimidazoles; Biphenyl Compounds; Blood Glucose; Fibrosis; Hypertension; Hypertrophy, Left Ventricular; Hypoglycemic Agents; Male; Matrix Metalloproteinases; Myocardium; Myocytes, Cardiac; Organ Size; Pioglitazone; Rats; Rats, Inbred Dahl; RNA, Messenger; Systole; Tetrazoles; Thiazolidinediones

2008
Comparison between single and combined treatment with candesartan and pioglitazone following transient focal ischemia in rat brain.
    Brain research, 2008, May-07, Volume: 1208

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Astrocytes; Benzimidazoles; Biphenyl Compounds; Brain; Cells, Cultured; Cerebrovascular Circulation; Disease Models, Animal; Drug Therapy, Combination; Gene Expression; Hypoglycemic Agents; Ischemic Attack, Transient; Magnetic Resonance Imaging; Male; Neurologic Examination; Pioglitazone; PPAR gamma; Rats; Rats, Wistar; Tetrazoles; Thiazolidinediones

2008
Combination therapy for treatment or prevention of atherosclerosis.
    Hypertension (Dallas, Tex. : 1979), 2008, Volume: 52, Issue:2

    Topics: Atherosclerosis; Benzimidazoles; Biphenyl Compounds; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Fenofibrate; Follow-Up Studies; Humans; Hypertension; Male; Pioglitazone; Risk Assessment; Severity of Illness Index; Tetrazoles; Thiazolidinediones; Treatment Outcome

2008
Pioglitazone enhances the antihypertensive and renoprotective effects of candesartan in Zucker obese rats fed a high-protein diet.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2008, Volume: 31, Issue:4

    Topics: Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Dietary Proteins; Drug Synergism; Hypertension, Renal; Hypoglycemic Agents; Immunohistochemistry; Kidney; Male; Metabolic Syndrome; Obesity; Pioglitazone; Rats; Rats, Zucker; Renal Insufficiency, Chronic; Risk Factors; Tetrazoles; Thiazolidinediones

2008
Potentiation by candesartan of protective effects of pioglitazone against type 2 diabetic cardiovascular and renal complications in obese mice.
    Journal of hypertension, 2010, Volume: 28, Issue:2

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Benzimidazoles; Biphenyl Compounds; Cyclic N-Oxides; Cytochrome b Group; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Drug Synergism; Hypoglycemic Agents; Kidney; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Obese; Myocardium; NADPH Oxidase 2; NADPH Oxidases; Obesity; Oxidative Stress; Pioglitazone; Spin Labels; Superoxide Dismutase; Tetrazoles; Thiazolidinediones

2010
Additive antifibrotic effects of pioglitazone and candesartan on experimental renal fibrosis in mice.
    Nephrology (Carlton, Vic.), 2010, Volume: 15, Issue:3

    Topics: Adiponectin; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biomarkers; Biphenyl Compounds; Chemokine CCL2; Collagen Type I; Collagen Type III; Disease Models, Animal; Drug Therapy, Combination; Fibrosis; Kidney; Kidney Diseases; Macrophages; Male; Mice; Mice, Inbred C57BL; Pioglitazone; Plasminogen Activator Inhibitor 1; PPAR gamma; RNA, Messenger; Severity of Illness Index; Tetrazoles; Thiazolidinediones; Transforming Growth Factor beta; Ureteral Obstruction

2010
Candesartan with pioglitazone protects against endothelial dysfunction and inflammatory responses in porcine coronary arteries implanted with sirolimus-eluting stents.
    Circulation journal : official journal of the Japanese Circulation Society, 2011, Volume: 75, Issue:5

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Coronary Vessels; Drug Therapy, Combination; Drug-Eluting Stents; Endothelium, Vascular; Hypoglycemic Agents; Inflammation; Pioglitazone; Protective Agents; Sirolimus; Sus scrofa; Tetrazoles; Thiazolidinediones; Treatment Outcome

2011
Effects of some anti-diabetic and cardioprotective agents on proliferation and apoptosis of human coronary artery endothelial cells.
    Cardiovascular diabetology, 2012, Mar-21, Volume: 11

    Topics: Apoptosis; Benzimidazoles; Biphenyl Compounds; Cardiotonic Agents; Cell Proliferation; Cell Survival; Cells, Cultured; Coronary Vessels; Endothelium, Vascular; Fluorobenzenes; Glucose; Humans; Hypoglycemic Agents; Insulin; Metformin; Pioglitazone; Pyrimidines; Rosuvastatin Calcium; Sulfonamides; Tetrazoles; Thiazolidinediones

2012
Differential effects of short-term treatment with two AT1 receptor blockers on diameter of pial arterioles in SHR.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Angiotensin Receptor Antagonists; Animals; Arterioles; Benzimidazoles; Benzoates; Biphenyl Compounds; Brain; Cerebrovascular Circulation; Hypertension; Male; Microcirculation; Muscle, Smooth; Nitric Oxide Synthase Type III; Pia Mater; Pioglitazone; PPAR gamma; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; RNA, Messenger; Telmisartan; Tetrazoles; Thiazolidinediones

2012
Effects of co-administration of candesartan with pioglitazone on inflammatory parameters in hypertensive patients with type 2 diabetes mellitus: a preliminary report.
    Cardiovascular diabetology, 2013, May-02, Volume: 12

    Topics: Adiponectin; Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Blood Pressure; C-Reactive Protein; Cohort Studies; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glycated Hemoglobin; Guanosine; Humans; Hypertension; Hypoglycemic Agents; Male; Middle Aged; Pioglitazone; Plasminogen Activator Inhibitor 1; Prospective Studies; Tetrazoles; Thiazolidinediones; Treatment Outcome; Vascular Cell Adhesion Molecule-1

2013