Compounds > candesartan

candesartan and pd 123319

candesartan has been researched along with pd 123319 in 89 studies

Research

Studies (89)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's23 (25.84)18.2507
2000's50 (56.18)29.6817
2010's16 (17.98)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kawahara, Y; Nakayama, I; Okuda, M; Tsuda, T; Yokoyama, M1
Hoshijima, M; Kawahara, Y; Nakayama, I; Okuda, M; Yokoyama, M1
Eguchi, S; Hirata, Y; Kanno, K; Kano, H1
Akimoto, Y; Aoki, H; Hirano, H; Karube, M; Koyama, N; Nagai, A; Nakamura, Y; Oda, T; Yoshimura, Y1
Aikawa, J; Fukazawa, M; Ishikawa, M; Moroi, M; Namiki, A; Yamaguchi, T1
Champion, HC; Kadowitz, PJ1
Abe, I; Fujii, K; Fujishima, M; Onaka, U1
Abe, K; Abe, M; Arima, S; Endo, Y; Ito, S; Ogawa, S; Omata, K; Takeuchi, K; Tsunoda, K; Yaoita, H1
Abe, K; Arima, S; Endo, Y; Ito, S; Omata, K; Takeuchi, K; Tsunoda, K; Yaoita, H1
Champion, HC; Czapla, MA; Kadowitz, PJ1
Chen, X; Fogo, A; Ichikawa, I; Inagami, T; Matsusaka, T; Niimura, F; Nishimura, H; Okubo, S; Tsuchida, S; Utsunomiya, H1
Hibi, K; Ishigami, T; Ishii, M; Kihara, M; Nyui, N; Tamura, K; Toya, Y; Umemura, S1
Averill, DB; Ferrario, CM; Matsumura, K1
Behrends, M; Dörge, H; Heusch, G; Jalowy, A; Schulz, R1
Arai, K; Demura, H; Imaki, T; Kobayashi, M; Miyazaki, H; Naruse, K; Naruse, M; Seki, T; Tanabe, A; Yoshimoto, T1
Ardaillou, R1
Bivalacqua, TJ; Champion, HC; Kadowitz, PJ; Lambert, DG; McNamara, DB1
Bivalacqua, TJ; Champion, HC; Dalal, A; Kadowitz, PJ; Lambert, DG1
Higaki, J; Moriguchi, K; Ogihara, T; Ohishi, M; Okamura, A; Rakugi, H; Suzuki, K; Takiuchi, S; Yanagitani, Y1
Fujita, T; Ishigami, T; Iwamoto, T; Kihara, M; Kobayashi, S; Toya, Y; Umemura, S; Yabana, M1
Sharma, A; Singh, M1
Bivalacqua, TJ; Champion, HC; Dalal, A; Kadowitz, PJ1
Barber, MN; Sampey, DB; Widdop, RE1
Ishii, K; Isobe, K; Kawakami, Y; Nakai, T; Nanmoku, T; Takekoshi, K1
Casado, S; Farré, J; Gómez, J; Jiménez, A; López-Blaya, A; López-Farré, A; Montón, M; Núñez, A; Sánchez de Miguel, L; Zalba, LR1
Eshima, K; Hirooka, Y; Koike, G; Matsuo, I; Sakai, K; Shigematsu, H; Takeshita, A1
Chen, Q; Chen, YE; Dzau, VJ; Horiuchi, M; Nyui, N; Pratt, RE; Takasaki, I; Tamura, K; Tamura, N; Umemura, S1
Bader, M; Böhm, M; Bricca, G; Ganten, D; Monti, J; Schinke, M1
Eshima, K; Hirooka, Y; Shigematsu, H; Shihara, M; Tagawa, T; Takeshita, A1
Frohlich, ED; Susic, D; Varagic, J1
Ishii, K; Isobe, K; Kawakami, Y; Nakai, T; Takekoshi, K1
Emoto, N; Fukuya, H; Ikeda, K; Nonaka, H; Okamura, H; Raharjo, SB; Rohman, MS; Yagita, K; Yokoyama, M1
Huang, Y; Wang, DH1
Ishii, K; Isobe, K; Kawakami, Y; Nakai, T; Shibuya, S; Takekoshi, K2
Bell, PD; Kovács, G; Peti-Peterdi, J; Rosivall, L1
Fukuuchi, Y; Inoue, K; Kobari, M; Otomo, M; Takao, M; Tanahashi, N; Tomita, M; Tomita, Y; Yokoyama, M1
Howes, LG; Phoon, S1
Durie, M; Levy, BI; Silvestre, JS; Tamarat, R1
He, G; Jing, T; Liu, J; Wang, G; Wang, H; Wu, H1
Fujimura, M; Hirose, T; Ishiura, Y; Kita, T; Myou, S; Nakao, S; Tachibana, H; Watanabe, K1
Holtz, J; Morawietz, H; Quinn, MT; Rueckschloss, U1
Aslam, S; Blau, J; Chabrashvili, T; Karber, A; Kitiyakara, C; Welch, WJ; Wilcox, CS1
Fujita, N; Manabe, H; Matsumoto, N; Naito, Y; Ochiai, J; Oka, S; Takagi, T; Uemura, M; Yoshida, N; Yoshikawa, T1
Duke, LM; Eppel, GA; Evans, RG; Widdop, RE1
Buikema, H; de Zeeuw, D; Gschwend, S; Henning, RH; Pinto, YM; van Gilst, WH1
Hayashi, M; Hirota, N; Ichihara, A; Kaneshiro, Y; Koura, Y; Okada, H; Saruta, T; Tada, Y; Tsuganezawa, H1
Lochard, N; Reudelhuber, TL; Silversides, DW; Thibault, G; Touyz, RM1
Hauner, H; Skurk, T; van Harmelen, V1
Alhenc-Gelas, F; Bergaya, S; Bloch-Faure, M; Boulanger, CM; Dong, Y; Hilgers, RH; Inagami, T; Lévy, BI; Meneton, P1
Harada, S; Kido, H; Morimoto, S; Nakagawa, M; Oguni, A; Sasaki, S; Takeda, K1
Ebinger, G; Fournié-Zaluski, MC; Michotte, Y; Sarre, S; Stragier, B; Vanderheyden, P; Vauquelin, G1
Jugdutt, BI; Menon, V1
Chen, K; Joseph, J; Joseph, L; Li, D; Mehta, JL1
Hakam, AC; Hussain, T1
Duke, LM; Evans, RG; Widdop, RE1
Duke, LM; Evans, RG; Kett, MM; Widdop, RE1
Gaspari, TA; Walters, PE; Widdop, RE1
Nagane, Y; Obara, D; Terayama, Y; Utsugisawa, K; Utsugisawa, T1
Iigaya, K; Kawai, A; Kumagai, H; Matsuura, T; Onami, T; Onimaru, H; Oshima, N; Sakata, K; Saruta, T; Sugaya, T1
Ebinger, G; Hristova, I; Michotte, Y; Sarre, S; Stragier, B1
Lu, Q; Wong, PT; Zhu, YZ1
Akutsu, H; Iwa, Y; Kizawa, H; Kondoh, R; Nagane, Y; Terayama, Y; Tohgi, H; Utsugisawa, K1
Carey, RM; Howell, NL; Padia, SH; Siragy, HM1
Edvinsson, L; Malmsjö, M; Nilsson, E; Vikman, P; Wackenfors, A1
Antus, B; Heemann, U; Lehmann, M; Liu, S; Lutz, J; Ouyang, N; Risch, K; Roos, M; Schmaderer, C1
Heidland, A; Kanase, N; Lakner, U; Rutkowski, P; Schmid, U; Schupp, N; Stopper, H1
Buikema, H; Morshuis, WJ; Nickenig, G; Plokker, HW; van de Wal, RM; van der Harst, P; van Gilst, WH; van Veldhuisen, DJ; Voors, AA; Wagenaar, LJ; Wassmann, S1
Carey, RM; Fournie-Zaluski, MC; Howell, NL; Kemp, BA; Padia, SH; Roques, BP2
Connors, SG; Mendonca, M; Palm, F; Welch, WJ; Wilcox, CS1
Carey, RM; Gildea, JJ; Howell, NL; Keller, SR; Kemp, BA; Padia, SH1
He, G; He, Y; Jing, T; Liu, J; Miao, L; Srivenugopal, KS; Wang, H1
Casselbrant, A; Edebo, A; Fändriks, L; Hallersund, P; Helander, HF; Jönson, C; Spak, E1
Gemici, B; Izgüt-Uysal, VN; Ongüt, G; Tan, R1
Arun, SN; Bollag, WB; George, MV; Olala, L; Parker, PM; Shapiro, BA1
Bi, J; Chappell, MC; Contag, SA; Rose, JC1
Mertens, B; Michotte, Y; Sarre, S; Vanderheyden, P1
Alterman, M; Bosnyak, S; Hallberg, A; Jones, ES; Welungoda, IK; Widdop, RE1
Fukuda, K; Hirooka, K; Itano, T; Mizote, M; Nakamura, T; Shiraga, F1
Allen, AM; Bassi, JK; Delbridge, LM; O'Callaghan, EL; Porrello, ER; Thomas, WG1
Hanif, K; Kamat, PK; Najmi, AK; Nath, C; Tota, S1
Bell, JF; Carey, RM; Howell, NL; Kemp, BA; Navar, LG; Padia, SH; Rottkamp, DM; Shao, W1
Goel, R; Hanif, K; Najmi, AK; Nath, C; Pachauri, SD; Rajasekar, N; Tota, S1
Beanlands, RS; DaSilva, JN; deKemp, RA; Hadizad, T; Ismail, BA; Kirkpatrick, SA; Lortie, M1
Aguilar, MI; Bosnyak, S; Del Borgo, M; Denton, K; Hilliard, L; Jones, ES; Khan, M; Perlmutter, P; Spizzo, I; Walters, P; Wang, Y; Widdop, RE1
Clifford, PS; Davis, MJ; Hill, MA; Hong, K; Hong, Z; Meininger, GA; Sun, Z; Yang, Y; Zhao, G1
Bessaguet, F; Danigo, A; Demiot, C; Desmoulière, A; Magy, L; Sturtz, F1
Bessaguet, F; Bouchenaki, H; Danigo, A; Demiot, C; Desmoulière, A; Duchesne, M; Magy, L; Richard, L; Sturtz, F1

Reviews

1 review(s) available for candesartan and pd 123319

ArticleYear
Angiotensin II receptors.
    Journal of the American Society of Nephrology : JASN, 1999, Volume: 10 Suppl 11

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Endothelium; Humans; Imidazoles; Kidney; Losartan; Peptide Fragments; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles

1999

Trials

1 trial(s) available for candesartan and pd 123319

ArticleYear
Forearm vasodilator response to angiotensin II in elderly women receiving candesartan: role of AT(2)- receptors.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2002, Volume: 3, Issue:1

    Topics: Aged; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cross-Over Studies; Double-Blind Method; Female; Forearm; Humans; Imidazoles; Middle Aged; Pyridines; Receptor, Angiotensin, Type 1; Regional Blood Flow; Tetrazoles; Vascular Resistance; Vasoconstrictor Agents; Vasodilation

2002

Other Studies

87 other study(ies) available for candesartan and pd 123319

ArticleYear
Angiotensin II inhibits cytokine-stimulated inducible nitric oxide synthase expression in vascular smooth muscle cells.
    The Journal of biological chemistry, 1994, Apr-15, Volume: 269, Issue:15

    Topics: Amino Acid Oxidoreductases; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Diglycerides; Enzyme Induction; Humans; Imidazoles; Interleukin-1; Kinetics; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Pyridines; Rats; Recombinant Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Tetrazoles; Tumor Necrosis Factor-alpha

1994
Angiotensin II transduces its signal to focal adhesions via angiotensin II type 1 receptors in vascular smooth muscle cells.
    FEBS letters, 1995, Jul-17, Volume: 368, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Cytoskeletal Proteins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Imidazoles; Muscle, Smooth, Vascular; Paxillin; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Pyridines; Rats; Receptors, Angiotensin; Signal Transduction; Tetrazoles

1995
Effect of an AT1 receptor antagonist (CV-11974) on angiotensin II-induced cardiomyocyte hypertrophy in vitro.
    Blood pressure. Supplement, 1994, Volume: 5

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blotting, Northern; Cardiomegaly; Cells, Cultured; DNA, Complementary; Endothelin-1; Endothelins; Heart; Imidazoles; Muscle, Smooth, Vascular; Myocardium; Protein Precursors; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Receptors, Endothelin; RNA, Messenger; Tetrazoles

1994
Angiotensin II induces ovulation and oocyte maturation in rabbit ovaries via the AT2 receptor subtype.
    Endocrinology, 1996, Volume: 137, Issue:4

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Benzimidazoles; Biphenyl Compounds; Cellular Senescence; Female; Imidazoles; Oocytes; Ovary; Ovulation Induction; Pyridines; Rabbits; Receptors, Angiotensin; Saralasin; Tetrazoles

1996
Stimulation of angiotensin subtype 2 receptor reduces basal cGMP levels in the neointima of rat aorta after balloon injury.
    General pharmacology, 1997, Volume: 28, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Benzimidazoles; Biphenyl Compounds; Catheterization; Cyclic AMP; Cyclic GMP; Imidazoles; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Pyridines; Rats; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Tunica Intima

1997
Analysis of the effects of candesartan in the mesenteric vascular bed of the cat.
    Hypertension (Dallas, Tex. : 1979), 1997, Volume: 30, Issue:5

    Topics: Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Vessels; Cats; Female; Imidazoles; Male; Perfusion; Pressure; Pyridines; Splanchnic Circulation; Tetrazoles

1997
Enhancement by exogenous and locally generated angiotensin II of purinergic neurotransmission via angiotensin type 1 receptor in the guinea-pig isolated mesenteric artery.
    British journal of pharmacology, 1997, Volume: 122, Issue:5

    Topics: Adenosine Triphosphate; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Electric Stimulation; Evoked Potentials; Female; Guinea Pigs; Imidazoles; In Vitro Techniques; Membrane Potentials; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Oligopeptides; Purinergic P2 Receptor Antagonists; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Suramin; Synaptic Transmission; Tetrazoles; Vasoconstrictor Agents

1997
Possible role of P-450 metabolite of arachidonic acid in vasodilator mechanism of angiotensin II type 2 receptor in the isolated microperfused rabbit afferent arteriole.
    The Journal of clinical investigation, 1997, Dec-01, Volume: 100, Issue:11

    Topics: 8,11,14-Eicosatrienoic Acid; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arachidonic Acid; Arterioles; Benzimidazoles; Biphenyl Compounds; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Endothelium, Vascular; Humans; Imidazoles; In Vitro Techniques; Kidney Glomerulus; Large-Conductance Calcium-Activated Potassium Channels; Male; Norepinephrine; Perfusion; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Pyridines; Rabbits; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetraethylammonium; Tetrazoles; Vasoconstrictor Agents; Vasodilator Agents

1997
Function of angiotensin II type 2 receptor in the postglomerular efferent arteriole.
    Kidney international. Supplement, 1997, Volume: 63

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arterioles; Benzimidazoles; Biphenyl Compounds; Imidazoles; In Vitro Techniques; Male; Microcirculation; Norepinephrine; Pyridines; Rabbits; Receptors, Angiotensin; Renal Circulation; Tetrazoles; Vasodilation

1997
Responses to angiotensin peptides are mediated by AT1 receptors in the rat.
    The American journal of physiology, 1998, Volume: 274, Issue:1

    Topics: Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Female; Hindlimb; Imidazoles; Losartan; Male; Norepinephrine; Peptide Fragments; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles

1998
Murine double nullizygotes of the angiotensin type 1A and 1B receptor genes duplicate severe abnormal phenotypes of angiotensinogen nullizygotes.
    The Journal of clinical investigation, 1998, Feb-15, Volume: 101, Issue:4

    Topics: Adrenal Glands; Anesthetics; Angiotensin II; Angiotensinogen; Animals; Benzimidazoles; beta-Galactosidase; Biphenyl Compounds; Blood Pressure; Imidazoles; Infusions, Intravenous; Kidney; Losartan; Mice; Mice, Knockout; Myocardium; Phenotype; Pyridines; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Saralasin; Staining and Labeling; Tetrazoles; Thiopental; Zygote

1998
Activation of angiotensinogen gene in cardiac myocytes by angiotensin II and mechanical stretch.
    The American journal of physiology, 1998, Volume: 275, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Animals, Newborn; Benzimidazoles; beta-Galactosidase; Biphenyl Compounds; Cells, Cultured; Chloramphenicol O-Acetyltransferase; Cycloheximide; Dactinomycin; Gene Expression Regulation; Heart; Heart Ventricles; Imidazoles; Liver; Lung; Myocardium; Promoter Regions, Genetic; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Recombinant Fusion Proteins; RNA, Messenger; RNA, Ribosomal, 18S; Stress, Mechanical; Tetrazoles; Transcription, Genetic; Transfection

1998
Angiotensin II acts at AT1 receptors in the nucleus of the solitary tract to attenuate the baroreceptor reflex.
    The American journal of physiology, 1998, Volume: 275, Issue:5

    Topics: Angiotensin Receptor Antagonists; Animals; Baroreflex; Benzimidazoles; Biphenyl Compounds; Imidazoles; Kidney; Male; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Solitary Nucleus; Sympathetic Nervous System; Tetrazoles

1998
Infarct size reduction by AT1-receptor blockade through a signal cascade of AT2-receptor activation, bradykinin and prostaglandins in pigs.
    Journal of the American College of Cardiology, 1998, Nov-15, Volume: 32, Issue:6

    Topics: Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Bradykinin; Bradykinin Receptor Antagonists; Cyclooxygenase Inhibitors; Drug Combinations; Female; Imidazoles; Indomethacin; Male; Myocardial Infarction; Prostaglandins; Pyridines; Receptors, Angiotensin; Signal Transduction; Swine; Swine, Miniature; Tetrazoles

1998
Angiotensin II stimulates both aldosterone secretion and DNA synthesis via type 1 but not type 2 receptors in bovine adrenocortical cells.
    Journal of endocrinological investigation, 1998, Volume: 21, Issue:10

    Topics: Adrenal Cortex; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Cattle; Cells, Cultured; DNA; Imidazoles; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Zona Glomerulosa

1998
The influence of candesartan and PD123319 on responses to angiotensin II in the hindquarters vascular bed of the rat.
    Journal of the American Society of Nephrology : JASN, 1999, Volume: 10 Suppl 11

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Calcium Channel Agonists; Dose-Response Relationship, Drug; Female; Hemodynamics; Hindlimb; Imidazoles; Injections, Intravenous; Male; Norepinephrine; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles; Vasoconstrictor Agents

1999
Effects of candesartan and PD123319 on responses to angiotensin II in the anesthetized mouse.
    Journal of the American Society of Nephrology : JASN, 1999, Volume: 10 Suppl 11

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Epinephrine; Imidazoles; Mice; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles

1999
Angiotensin II type 1 receptor-mediated peroxide production in human macrophages.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 33, Issue:1 Pt 2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Cell Differentiation; Humans; Imidazoles; Kinetics; Leukemia, Monocytic, Acute; Macrophages; Oxidative Stress; Peroxides; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetradecanoylphorbol Acetate; Tetrazoles; Tumor Cells, Cultured

1999
Angiotensin II inhibits interleukin-1 beta-induced nitric oxide production in cultured rat mesangial cells.
    Kidney international, 1999, Volume: 55, Issue:4

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antibodies; Benzimidazoles; Biphenyl Compounds; Blotting, Northern; Cells, Cultured; Gene Expression; Glomerular Mesangium; Imidazoles; Interleukin-1; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetrazoles; Transforming Growth Factor beta

1999
Role of angiotensin in cardioprotective effect of ischemic preconditioning.
    Journal of cardiovascular pharmacology, 1999, Volume: 33, Issue:5

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Coronary Circulation; Creatine Kinase; Female; Heart Rate; Imidazoles; In Vitro Techniques; Ischemic Preconditioning, Myocardial; L-Lactate Dehydrogenase; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Pyridines; Rats; Rats, Wistar; Tetrazoles

1999
Role of AT(1) receptors and autonomic nervous system in mediating acute pressor responses to ANG II in anesthetized mice.
    The American journal of physiology, 1999, Volume: 277, Issue:5

    Topics: Adrenergic beta-Antagonists; Anesthesia; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Atropine; Autonomic Nervous System; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cardiac Output; Dose-Response Relationship, Drug; Enalaprilat; Heart Rate; Hexamethonium; Imidazoles; Mice; Mice, Inbred Strains; Parasympatholytics; Phentolamine; Propranolol; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Vascular Resistance; Vasoconstrictor Agents

1999
AT(2) receptor stimulation enhances antihypertensive effect of AT(1) receptor antagonist in hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 34, Issue:5

    Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Drug Synergism; Hypertension; Imidazoles; Male; Oligopeptides; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Tetrazoles; Vasodilation

1999
Angiotensin-II subtype 2 receptor agonist (CGP-42112) inhibits catecholamine biosynthesis in cultured porcine adrenal medullary chromaffin cells.
    Biochemical and biophysical research communications, 2000, Jun-07, Volume: 272, Issue:2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenal Medulla; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Binding, Competitive; Biphenyl Compounds; Catecholamines; Cells, Cultured; Chromaffin Cells; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Induction; Imidazoles; Oligopeptides; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Swine; Tetrazoles; Tyrosine 3-Monooxygenase

2000
Comparative effects of angiotensin II AT-1-type receptor antagonists in vitro on human platelet activation.
    Journal of cardiovascular pharmacology, 2000, Volume: 35, Issue:6

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adult; Angiotensin II; Angiotensin Receptor Antagonists; Antibodies, Monoclonal; Benzimidazoles; Benzoates; Binding, Competitive; Biphenyl Compounds; Blood Platelets; Dose-Response Relationship, Drug; Humans; Imidazoles; Irbesartan; Losartan; Platelet Activation; Pyridines; Radioligand Assay; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Telmisartan; Tetrazoles; Thromboxane A2; Time Factors; Valine; Valsartan

2000
Angiotensin in the nucleus tractus solitarii contributes to neurogenic hypertension caused by chronic nitric oxide synthase inhibition.
    Hypertension (Dallas, Tex. : 1979), 2000, Volume: 36, Issue:2

    Topics: Angiotensin Receptor Antagonists; Angiotensins; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Brain Stem; Cerebral Ventricles; Enzyme Inhibitors; Gene Expression Regulation; Heart Rate; Hexamethonium; Hypertension; Imidazoles; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Peptidyl-Dipeptidase A; Pyridines; Rats; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Solitary Nucleus; Sympathetic Nervous System; Tetrazoles

2000
Expression of renin-angiotensin system and extracellular matrix genes in cardiovascular cells and its regulation through AT1 receptor.
    Molecular and cellular biochemistry, 2000, Volume: 212, Issue:1-2

    Topics: Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Animals, Newborn; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Extracellular Matrix; Fibronectins; Heart; Imidazoles; Muscle, Smooth, Vascular; Myocardium; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System; RNA, Messenger; Tetrazoles; Transcription, Genetic; Transfection

2000
Glial angiotensinogen regulates brain angiotensin II receptors in transgenic rats TGR(ASrAOGEN).
    American journal of physiology. Regulatory, integrative and comparative physiology, 2001, Volume: 280, Issue:1

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Antihypertensive Agents; Astrocytes; Autoradiography; Benzimidazoles; Biphenyl Compounds; Blood-Brain Barrier; Brain Chemistry; Diabetes Insipidus; Drinking; Imidazoles; Injections, Intraventricular; Iodine Radioisotopes; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Antisense; Salts; Subfornical Organ; Tetrazoles; Vasoconstrictor Agents

2001
Endogenous angiotensin II in the NTS contributes to sympathetic activation in rats with aortocaval shunt.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2001, Volume: 280, Issue:6

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Arteriovenous Shunt, Surgical; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Echocardiography; Heart Rate; Hemodynamics; Imidazoles; Kidney; Male; Microinjections; Pyridines; Rats; Rats, Inbred WKY; Solitary Nucleus; Sympathetic Nervous System; Tetrazoles; Venae Cavae

2001
Coronary hemodynamic and ventricular responses to angiotensin type 1 receptor inhibition in SHR: interaction with angiotensin type 2 receptors.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:6

    Topics: Angiotensin Receptor Antagonists; Animals; Aorta; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Coronary Circulation; Heart Rate; Heart Ventricles; Hemodynamics; Hydroxyproline; Hypertension; Imidazoles; Male; Organ Size; Pyridines; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles; Vascular Resistance

2001
Activation of angiotensin II subtype 2 receptor induces catecholamine release in an extracellular Ca(2+)-dependent manner through a decrease of cyclic guanosine 3',5'-monophosphate production in cultured porcine adrenal medullary chromaffin Cells.
    Endocrinology, 2001, Volume: 142, Issue:7

    Topics: Adrenal Medulla; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Calcium; Catecholamines; Cells, Cultured; Chromaffin Cells; Cyclic GMP; Extracellular Space; Imidazoles; Inositol 1,4,5-Trisphosphate; Intracellular Membranes; Oligopeptides; Pyridines; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Swine; Tetrazoles; Virulence Factors, Bordetella

2001
Angiotensin II induces circadian gene expression of clock genes in cultured vascular smooth muscle cells.
    Circulation, 2001, Oct-09, Volume: 104, Issue:15

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; ARNTL Transcription Factors; Basic Helix-Loop-Helix Transcription Factors; Benzimidazoles; Biological Clocks; Biomarkers; Biphenyl Compounds; Blotting, Northern; Cell Cycle Proteins; Cells, Cultured; Circadian Rhythm; DNA-Binding Proteins; Gene Expression; Imidazoles; Male; Mice; Mice, Inbred BALB C; Muscle, Smooth, Vascular; Nuclear Proteins; Period Circadian Proteins; Pyridines; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Tetrazoles; Transcription Factors

2001
Role of AT1 and AT2 receptor subtypes in salt-sensitive hypertension induced by sensory nerve degeneration.
    Journal of hypertension, 2001, Volume: 19, Issue:10

    Topics: Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Diuresis; Dose-Response Relationship, Drug; Drug Synergism; Ganglia, Spinal; Hypertension; Imidazoles; Male; Natriuresis; Nerve Degeneration; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reference Values; Renin; Sodium, Dietary; Tetrazoles

2001
Angiotensin subtype-2 receptor (AT2 ) negatively regulates subtype-1 receptor (AT1 ) in signal transduction pathways in cultured porcine adrenal medullary chromaffin cells.
    Journal of hypertension, 2001, Volume: 19, Issue:11

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Chromaffin Cells; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; DNA-Binding Proteins; Drug Combinations; Enzyme Activation; Imidazoles; Isoenzymes; Milk Proteins; Mitogen-Activated Protein Kinases; Protein Kinase C; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Signal Transduction; STAT1 Transcription Factor; STAT3 Transcription Factor; STAT5 Transcription Factor; Swine; Tetrazoles; Trans-Activators

2001
Angiotensin II directly stimulates macula densa Na-2Cl-K cotransport via apical AT(1) receptors.
    American journal of physiology. Renal physiology, 2002, Volume: 282, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biological Transport; Biphenyl Compounds; Cytosol; Diuretics; Furosemide; Imidazoles; Kidney Glomerulus; Microscopy, Fluorescence; Pyridines; Rabbits; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Sodium; Sodium Chloride; Sodium-Potassium-Chloride Symporters; Tetrazoles; Vasoconstrictor Agents

2002
Dilatation of cerebral parenchymal vessels mediated by angiotensin type 1 receptor in cats.
    Neuroscience letters, 2002, Jan-25, Volume: 318, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cats; Cerebral Arteries; Cerebral Cortex; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Female; Imidazoles; Male; Microcirculation; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Vasodilation

2002
Angiotensin II type 2 receptor counter-regulates type 1 receptor in catecholamine synthesis in cultured porcine adrenal medullary chromaffin cells.
    Hypertension (Dallas, Tex. : 1979), 2002, Volume: 39, Issue:1

    Topics: Adrenal Medulla; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Catecholamines; Cells, Cultured; Cyclic GMP; Imidazoles; Phosphodiesterase Inhibitors; Protein Kinase C; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Swine; Tetrazoles; Tyrosine 3-Monooxygenase

2002
Angiotensin II angiogenic effect in vivo involves vascular endothelial growth factor- and inflammation-related pathways.
    Laboratory investigation; a journal of technical methods and pathology, 2002, Volume: 82, Issue:6

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antibodies, Monoclonal; Benzimidazoles; Biphenyl Compounds; Collagen; Cyclooxygenase 2; Disease Models, Animal; Drug Combinations; Drug Therapy, Combination; Endothelial Growth Factors; Female; Imidazoles; Isoenzymes; Laminin; Lymphokines; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Pathologic; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Prostaglandin-Endoperoxide Synthases; Proteoglycans; Pyridines; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Sulfonamides; Tetrazoles; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2002
Role of angiotensin II and angiotensin II receptors in vascular smooth muscle cell migration in vitro.
    Chinese medical journal, 2002, Volume: 115, Issue:5

    Topics: Actins; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Cell Movement; Cells, Cultured; Cytoskeleton; Dose-Response Relationship, Drug; Female; Focal Adhesions; Imidazoles; Immunohistochemistry; Male; Muscle, Smooth, Vascular; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Tetrazoles

2002
Effect of intranasal administration of CV-11974, a type 1 angiotensin II receptor antagonist, on airway hyperresponsiveness and airway inflammation induced by antigen inhalation in guinea pigs.
    International archives of allergy and immunology, 2002, Volume: 129, Issue:1

    Topics: Administration, Inhalation; Administration, Intranasal; Angiotensin Receptor Antagonists; Animals; Antigens; Benzimidazoles; Biphenyl Compounds; Bronchial Hyperreactivity; Dose-Response Relationship, Drug; Eosinophils; Guinea Pigs; Imidazoles; Male; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles

2002
Dose-dependent regulation of NAD(P)H oxidase expression by angiotensin II in human endothelial cells: protective effect of angiotensin II type 1 receptor blockade in patients with coronary artery disease.
    Arteriosclerosis, thrombosis, and vascular biology, 2002, Nov-01, Volume: 22, Issue:11

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Coronary Artery Bypass; Coronary Artery Disease; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Imidazoles; Mammary Arteries; Membrane Glycoproteins; NADH, NADPH Oxidoreductases; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Preoperative Care; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System; Retrospective Studies; Superoxides; Tetrazoles; Umbilical Veins

2002
Effects of ANG II type 1 and 2 receptors on oxidative stress, renal NADPH oxidase, and SOD expression.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2003, Volume: 285, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Body Weight; Gene Expression Regulation, Enzymologic; Imidazoles; Isoprostanes; Kidney; Male; Malondialdehyde; NADPH Oxidases; Oxidative Stress; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Superoxide Dismutase; Tetrazoles; Vasoconstrictor Agents

2003
An AT1-receptor antagonist and an angiotensin-converting enzyme inhibitor protect against hypoxia-induced apoptosis in human aortic endothelial cells through upregulation of endothelial cell nitric oxide synthase activity.
    Shock (Augusta, Ga.), 2003, Volume: 19, Issue:6

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Aorta; Apoptosis; Benzimidazoles; Biphenyl Compounds; Bradykinin; Caspase 3; Caspases; Cell Hypoxia; Cells, Cultured; Endothelium, Vascular; Humans; Imidazoles; Necrosis; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Pyridines; Tetrazoles; Thiazepines

2003
Disparate roles of AT2 receptors in the renal cortical and medullary circulations of anesthetized rabbits.
    Hypertension (Dallas, Tex. : 1979), 2003, Volume: 42, Issue:2

    Topics: Angiotensin Receptor Antagonists; Angiotensins; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Hemodynamics; Imidazoles; Kidney Cortex; Kidney Medulla; Laser-Doppler Flowmetry; Male; Oligopeptides; Peptides; Pyridines; Rabbits; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Regional Blood Flow; Renal Circulation; Tetrazoles; Vasoconstriction; Vasodilation

2003
Myogenic constriction is increased in mesenteric resistance arteries from rats with chronic heart failure: instantaneous counteraction by acute AT1 receptor blockade.
    British journal of pharmacology, 2003, Volume: 139, Issue:7

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Bridged Bicyclo Compounds, Heterocyclic; Captopril; Chronic Disease; Coronary Vessels; Disease Models, Animal; Endothelium-Dependent Relaxing Factors; Endothelium, Vascular; Fatty Acids, Unsaturated; Heart; Heart Failure; Hydrazines; Imidazoles; Indomethacin; Lisinopril; Losartan; Male; Mesenteric Arteries; Nitric Oxide; omega-N-Methylarginine; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Superoxide Dismutase; Sympathetic Nervous System; Tetrazoles; Tetrodotoxin; Vascular Resistance

2003
Angiotensin II type 2 receptor inhibits prorenin processing in juxtaglomerular cells.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2003, Volume: 26, Issue:11

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Culture Media; Imidazoles; Immunohistochemistry; Juxtaglomerular Apparatus; Male; Oligopeptides; Pyridines; Rats; Rats, Sprague-Dawley; Renin; Tetrazoles

2003
Chronic production of angiotensin IV in the brain leads to hypertension that is reversible with an angiotensin II AT1 receptor antagonist.
    Circulation research, 2004, Jun-11, Volume: 94, Issue:11

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Allosteric Regulation; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Brain; Calcium Signaling; CHO Cells; Cricetinae; Cricetulus; Gene Expression; Genes, Synthetic; Glial Fibrillary Acidic Protein; Globins; Humans; Hypertension; Imidazoles; Mice; Mice, Transgenic; Organ Specificity; Protein Sorting Signals; Pyridines; Rabbits; Receptor, Angiotensin, Type 1; Recombinant Fusion Proteins; Renin; Renin-Angiotensin System; Tetrazoles; Transgenes

2004
Angiotensin II stimulates the release of interleukin-6 and interleukin-8 from cultured human adipocytes by activation of NF-kappaB.
    Arteriosclerosis, thrombosis, and vascular biology, 2004, Volume: 24, Issue:7

    Topics: Adipocytes; Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Electrophoretic Mobility Shift Assay; Female; Humans; Imidazoles; Inflammation; Interleukin-6; Interleukin-8; NF-kappa B; Nitriles; Phosphorylation; Protein Processing, Post-Translational; Protein Transport; Pyridines; Receptor, Angiotensin, Type 1; RNA, Messenger; Sulfones; Tetrazoles; Transcription Factor RelA; Transcriptional Activation

2004
Flow-dependent dilation mediated by endogenous kinins requires angiotensin AT2 receptors.
    Circulation research, 2004, Jun-25, Volume: 94, Issue:12

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Bradykinin; Bradykinin B2 Receptor Antagonists; Carotid Arteries; Hemorheology; Imidazoles; Losartan; Male; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Mice, Knockout; Phenylephrine; Pyridines; Receptor, Angiotensin, Type 2; Receptor, Bradykinin B2; Tetrazoles; Tissue Kallikreins; Vasodilation; Vasodilator Agents

2004
Effects of angiotensin II type 1 receptor antagonist on pressor responses to pulsatile compression of the rostral ventrolateral medulla in rats.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2004, Volume: 27, Issue:6

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Excitatory Amino Acid Antagonists; Glutamic Acid; Hypertension; Imidazoles; Injections, Intravenous; Kynurenic Acid; Male; Medulla Oblongata; Pulsatile Flow; Pyridines; Rats; Rats, Wistar; Sympathetic Nervous System; Tetrazoles; Vasoconstrictor Agents

2004
Metabolism of angiotensin II is required for its in vivo effect on dopamine release in the striatum of the rat.
    Journal of neurochemistry, 2004, Volume: 90, Issue:5

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Hemoglobins; Imidazoles; Male; Methionine; Microdialysis; Naltrexone; Narcotic Antagonists; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Sulfonic Acids; Tetrazoles; Time Factors

2004
AT2 receptor and apoptosis during AT1 receptor blockade in reperfused myocardial infarction in the rat.
    Molecular and cellular biochemistry, 2004, Volume: 262, Issue:1-2

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Benzimidazoles; Biphenyl Compounds; Hemodynamics; Imidazoles; Myocardial Infarction; Myocardial Reperfusion; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Tetrazoles; Up-Regulation; Ventricular Dysfunction, Left

2004
Transforming growth factor beta receptor endoglin is expressed in cardiac fibroblasts and modulates profibrogenic actions of angiotensin II.
    Circulation research, 2004, Dec-10, Volume: 95, Issue:12

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Antibodies, Monoclonal; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Collagen Type I; Endoglin; Fibroblasts; Flavonoids; Gene Expression Regulation; Imidazoles; Intracellular Signaling Peptides and Proteins; Losartan; MAP Kinase Signaling System; Matrix Metalloproteinase 1; Myocardium; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Transforming Growth Factor beta; RNA, Messenger; Signal Transduction; Tetrazoles; Valine; Valsartan

2004
Renal angiotensin II type-2 receptors are upregulated and mediate the candesartan-induced natriuresis/diuresis in obese Zucker rats.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 45, Issue:2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Diuresis; Imidazoles; Kidney; Male; Natriuresis; Obesity; Oligopeptides; Pyridines; Rats; Rats, Zucker; Receptor, Angiotensin, Type 2; Tetrazoles; Up-Regulation

2005
AT2 receptors contribute to acute blood pressure-lowering and vasodilator effects of AT1 receptor antagonism in conscious normotensive but not hypertensive rats.
    American journal of physiology. Heart and circulatory physiology, 2005, Volume: 288, Issue:5

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Consciousness; Heart Rate; Hypertension; Imidazoles; Male; Pyridines; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renal Artery; Tail; Tetrazoles; Vasoconstrictor Agents; Vasodilator Agents

2005
AT(2) receptors mediate tonic renal medullary vasoconstriction in renovascular hypertension.
    British journal of pharmacology, 2005, Volume: 144, Issue:4

    Topics: Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension, Renovascular; Imidazoles; Kidney Medulla; Laser-Doppler Flowmetry; Male; Pyridines; Rats; Rats, Sprague-Dawley; Renal Artery; Renal Circulation; Tetrazoles; Time Factors; Vasoconstriction

2005
Angiotensin-(1-7) acts as a vasodepressor agent via angiotensin II type 2 receptors in conscious rats.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 45, Issue:5

    Topics: Angiotensin I; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Drug Combinations; Imidazoles; Male; Peptide Fragments; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 2; Tetrazoles; Vasoconstrictor Agents

2005
Candesartan prevents angiotensin II-induced facilitation of hypoxic neuronal damage through PKCdelta inhibition.
    Brain research. Molecular brain research, 2005, Apr-27, Volume: 135, Issue:1-2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blotting, Western; Cell Death; Cell Hypoxia; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression Regulation; Imidazoles; In Situ Nick-End Labeling; Mice; PC12 Cells; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Pyridines; Rats; Serine; Tetrazoles; Time Factors; Transfection

2005
Electrophysiological properties of rostral ventrolateral medulla neurons in angiotensin II 1a receptor knockout mice.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 46, Issue:2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Electrophysiology; Imidazoles; Medulla Oblongata; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pyridines; Receptor, Angiotensin, Type 1; Tetrazoles

2005
In vivo characterization of the angiotensin-(1-7)-induced dopamine and gamma-aminobutyric acid release in the striatum of the rat.
    The European journal of neuroscience, 2005, Volume: 22, Issue:3

    Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Chromatography; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; gamma-Aminobutyric Acid; Imidazoles; Male; Microdialysis; NG-Nitroarginine Methyl Ester; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Sulfonic Acids; Tetrazoles; Time Factors

2005
Neuroprotective effects of candesartan against cerebral ischemia in spontaneously hypertensive rats.
    Neuroreport, 2005, Nov-28, Volume: 16, Issue:17

    Topics: Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Body Weight; Brain Ischemia; Gene Expression; Heart Rate; Hypertension; Imidazoles; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; Pyridines; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles; Vasoconstrictor Agents

2005
Biphasic effects of angiotensin II and receptor antagonism on aggregability and protein kinase C phosphorylation in human platelets.
    Thrombosis and haemostasis, 2005, Volume: 94, Issue:5

    Topics: Adult; Aged; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Blood Platelets; Female; Humans; Imidazoles; In Vitro Techniques; Isoenzymes; Male; Middle Aged; Phosphorylation; Platelet Aggregation; Protein Kinase C; Pyridines; Receptor, Angiotensin, Type 1; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents

2005
Renal angiotensin type 2 receptors mediate natriuresis via angiotensin III in the angiotensin II type 1 receptor-blocked rat.
    Hypertension (Dallas, Tex. : 1979), 2006, Volume: 47, Issue:3

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin III; Animals; Benzimidazoles; Biphenyl Compounds; Dose-Response Relationship, Drug; Drug Combinations; Imidazoles; Kidney; Natriuresis; Nephrectomy; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Sodium Chloride, Dietary; Tetrazoles

2006
Angiotensin II-induced vasodilatation in cerebral arteries is mediated by endothelium-derived hyperpolarising factor.
    European journal of pharmacology, 2006, Feb-15, Volume: 531, Issue:1-3

    Topics: Adenosine Triphosphate; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apamin; Benzimidazoles; Biological Factors; Biphenyl Compounds; Cerebral Arteries; Charybdotoxin; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Imidazoles; In Vitro Techniques; Indomethacin; Male; Neurotoxins; Nitric Oxide Synthase; Nitroarginine; Pyridines; Rats; Rats, Sprague-Dawley; Serotonin; Tetrazoles; Vasoconstriction; Vasoconstrictor Agents

2006
Angiotensin type 1 and type 2 receptor blockade in chronic allograft nephropathy.
    Kidney international, 2006, Volume: 70, Issue:6

    Topics: Angiotensin Receptor Antagonists; Animals; Apoptosis; Benzimidazoles; Biphenyl Compounds; Chronic Disease; Drug Interactions; Follow-Up Studies; Imidazoles; Kidney Transplantation; Male; Nephrotic Syndrome; Proteinuria; Pyridines; Rats; Rats, Inbred F344; Rats, Inbred Lew; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Tetrazoles; Time Factors; Transplantation, Homologous; Tumor Suppressor Protein p53

2006
Angiotensin II-induced genomic damage in renal cells can be prevented by angiotensin II type 1 receptor blockage or radical scavenging.
    American journal of physiology. Renal physiology, 2007, Volume: 292, Issue:5

    Topics: Acetylcysteine; alpha-Tocopherol; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Cell Line; Cell Nucleus; Comet Assay; DNA Damage; Dose-Response Relationship, Drug; Flow Cytometry; Free Radical Scavengers; Humans; Imidazoles; Kidney; Pyridines; Rats; Reactive Oxygen Species; Swine; Tetrazoles

2007
Angiotensin II type 2 receptor vasoactivity in internal mammary arteries of patients with coronary artery disease.
    Journal of cardiovascular pharmacology, 2007, Volume: 50, Issue:4

    Topics: Acetylcholine; Adrenergic alpha-Antagonists; Adult; Aged; Aged, 80 and over; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Coronary Artery Disease; Female; Gene Expression; Humans; Imidazoles; In Vitro Techniques; Male; Mammary Arteries; Middle Aged; Oligopeptides; Phentolamine; Phenylephrine; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sodium Nitrite; Tetrazoles; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2007
Conversion of renal angiotensin II to angiotensin III is critical for AT2 receptor-mediated natriuresis in rats.
    Hypertension (Dallas, Tex. : 1979), 2008, Volume: 51, Issue:2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin III; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; CD13 Antigens; Drug Synergism; Female; Glutamyl Aminopeptidase; Imidazoles; Kidney; Methionine; Natriuresis; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Sodium, Dietary; Sulfonic Acids; Tetrazoles

2008
Angiotensin II type 2 receptors and nitric oxide sustain oxygenation in the clipped kidney of early Goldblatt hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 2008, Volume: 51, Issue:2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Enalaprilat; Enzyme Inhibitors; Glomerular Filtration Rate; Hypertension, Renovascular; Imidazoles; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxygen; Partial Pressure; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renal Circulation; Surgical Instruments; Tetrazoles; Vascular Resistance

2008
Intrarenal angiotensin III infusion induces natriuresis and angiotensin type 2 receptor translocation in Wistar-Kyoto but not in spontaneously hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 2009, Volume: 53, Issue:2

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin III; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cell Membrane; Disease Models, Animal; Female; Hypertension; Imidazoles; Kidney Tubules, Proximal; Natriuresis; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sodium; Tetrazoles

2009
Conditional expression of type 2 angiotensin II receptor in rat vascular smooth muscle cells reveals the interplay of the angiotensin system in matrix metalloproteinase 2 expression and vascular remodeling.
    International journal of molecular medicine, 2009, Volume: 24, Issue:1

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Endothelium, Vascular; Imidazoles; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Muscle, Smooth, Vascular; Pyridines; Rats; Receptor, Angiotensin, Type 2; Signal Transduction; Tetrazoles

2009
Angiotensin II receptors are expressed and functional in human esophageal mucosa.
    American journal of physiology. Gastrointestinal and liver physiology, 2009, Volume: 297, Issue:5

    Topics: Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Benzimidazoles; Biopsy; Biphenyl Compounds; Blood Vessels; Electric Impedance; Electrophysiological Phenomena; Epithelial Cells; Esophagus; Female; Gene Expression; Humans; Hydrochloric Acid; Imidazoles; Losartan; Male; Middle Aged; Mucous Membrane; Peptidyl-Dipeptidase A; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles

2009
Expressions of inducible nitric oxide synthase and cyclooxygenase-2 in gastric ischemia-reperfusion: role of angiotensin II.
    The Journal of surgical research, 2010, Jun-01, Volume: 161, Issue:1

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Captopril; Cyclooxygenase 2; Dinoprostone; Gastritis; Imidazoles; Male; Neutrophils; Nitric Oxide; Nitric Oxide Synthase Type II; Peroxidase; Pyridines; Rats; Rats, Wistar; Reperfusion Injury; Tetrazoles

2010
Angiotensin II-activated protein kinase D mediates acute aldosterone secretion.
    Molecular and cellular endocrinology, 2010, Apr-12, Volume: 317, Issue:1-2

    Topics: Adenoviridae; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Cattle; Enzyme Activation; Imidazoles; Mutant Proteins; Potassium; Protein Kinase C; Pyridines; Receptor, Angiotensin, Type 1; Tetradecanoylphorbol Acetate; Tetrazoles; Time Factors; Zona Glomerulosa

2010
Intrarenal aminopeptidase N inhibition restores defective angiontesin II type 2-mediated natriuresis in spontaneously hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:2

    Topics: Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; CD13 Antigens; Disease Models, Animal; Female; Glomerular Filtration Rate; Hypertension; Imidazoles; Lithium; Natriuresis; Probability; Pyridines; Random Allocation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 2; Sodium; Tetrazoles

2010
Developmental effect of antenatal exposure to betamethasone on renal angiotensin II activity in the young adult sheep.
    American journal of physiology. Renal physiology, 2010, Volume: 298, Issue:4

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Benzimidazoles; Betamethasone; Biphenyl Compounds; Blood Pressure; Female; Glomerular Filtration Rate; Glucocorticoids; Imidazoles; Infusions, Intra-Arterial; Kidney; Lithium; Male; Organ Size; Pregnancy; Prenatal Exposure Delayed Effects; Pyridines; Random Allocation; Renal Blood Flow, Effective; Sheep; Sodium; Tetrazoles; Vascular Resistance

2010
Direct angiotensin II type 2 receptor stimulation decreases dopamine synthesis in the rat striatum.
    Neuropharmacology, 2010, Volume: 58, Issue:7

    Topics: 3,4-Dihydroxyphenylacetic Acid; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benzimidazoles; Biphenyl Compounds; Catheterization; Central Nervous System Agents; Corpus Striatum; Dopa Decarboxylase; Dopamine; Extracellular Space; Hydrazines; Imidazoles; Levodopa; Male; Microdialysis; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles; Tyrosine 3-Monooxygenase

2010
Stimulation of angiotensin AT2 receptors by the non-peptide agonist, Compound 21, evokes vasodepressor effects in conscious spontaneously hypertensive rats.
    British journal of pharmacology, 2010, Feb-01, Volume: 159, Issue:3

    Topics: Animals; Aorta; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blood Vessels; Cardiovascular System; Consciousness; Imidazoles; Male; Mice; Mice, Inbred Strains; Peptides; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2010
Neuroprotection against retinal ischemia-reperfusion injury by blocking the angiotensin II type 1 receptor.
    Investigative ophthalmology & visual science, 2010, Volume: 51, Issue:7

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Bradykinin; Bradykinin B2 Receptor Antagonists; Captopril; Cell Survival; Electroretinography; Enzyme-Linked Immunosorbent Assay; Female; Imidazoles; Immunoenzyme Techniques; Neuroprotective Agents; Pyridines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Reperfusion Injury; Retina; Retinal Diseases; Retinal Ganglion Cells; Tetrazoles

2010
Regulation of angiotensinogen by angiotensin II in mouse primary astrocyte cultures.
    Journal of neurochemistry, 2011, Volume: 119, Issue:1

    Topics: Adenoviridae; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Astrocytes; Benzimidazoles; Biphenyl Compounds; Brain; Brain Chemistry; Cells, Cultured; Dexamethasone; Feedback, Physiological; Imidazoles; Immunohistochemistry; Inositol Phosphates; Liver; Mice; Mice, Inbred C57BL; Pyridines; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Tetrazoles

2011
Role of central angiotensin receptors in scopolamine-induced impairment in memory, cerebral blood flow, and cholinergic function.
    Psychopharmacology, 2012, Volume: 222, Issue:2

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Avoidance Learning; Benzimidazoles; Biphenyl Compounds; Cerebral Cortex; Hippocampus; Hypertension; Imidazoles; Laser-Doppler Flowmetry; Male; Maze Learning; Memory Disorders; Mice; Muscarinic Antagonists; Oxidative Stress; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Scopolamine; Tetrazoles

2012
Intrarenal angiotensin III is the predominant agonist for proximal tubule angiotensin type 2 receptors.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 60, Issue:2

    Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin III; Animals; Benzimidazoles; Biphenyl Compounds; Female; Imidazoles; Kidney Tubules, Proximal; Models, Animal; Natriuresis; Peptide Fragments; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Tetrazoles

2012
Effect of angiotensin II on spatial memory, cerebral blood flow, cholinergic neurotransmission, and brain derived neurotrophic factor in rats.
    Psychopharmacology, 2013, Volume: 226, Issue:2

    Topics: Acetylcholine; Acetylcholinesterase; Adenosine Triphosphate; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Brain-Derived Neurotrophic Factor; Cerebrovascular Circulation; Cholinesterase Inhibitors; Donepezil; Hippocampus; Imidazoles; Indans; Male; Melatonin; Memory; Oxidative Stress; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Tetrazoles

2013
Analysis of [11C]methyl-candesartan kinetics in the rat kidney for the assessment of angiotensin II type 1 receptor density in vivo with PET.
    Nuclear medicine and biology, 2013, Volume: 40, Issue:2

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Carbon Radioisotopes; Imidazoles; Kidney; Kinetics; Male; Models, Biological; Positron-Emission Tomography; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Reproducibility of Results; Tetrazoles

2013
β-Pro7Ang III is a novel highly selective angiotensin II type 2 receptor (AT2R) agonist, which acts as a vasodepressor agent via the AT2R in conscious spontaneously hypertensive rats.
    Clinical science (London, England : 1979), 2015, Volume: 129, Issue:6

    Topics: Amino Acid Sequence; Analysis of Variance; Angiotensin II Type 2 Receptor Blockers; Angiotensin III; Animals; Aorta, Thoracic; Benzimidazoles; Binding, Competitive; Biphenyl Compounds; Drug Stability; HEK293 Cells; Humans; Hypertension; Imidazoles; In Vitro Techniques; Inhibitory Concentration 50; Isometric Contraction; Male; Mice; Muscle, Smooth, Vascular; Pyridines; Rats; Receptors, Angiotensin; Tetrazoles; Vasoconstrictor Agents; Vasodilation

2015
Mechanical activation of angiotensin II type 1 receptors causes actin remodelling and myogenic responsiveness in skeletal muscle arterioles.
    The Journal of physiology, 2016, 12-01, Volume: 594, Issue:23

    Topics: Abdominal Muscles; Actins; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Arterioles; Benzimidazoles; Biphenyl Compounds; Captopril; Cells, Cultured; Diglycerides; Imidazoles; Indoles; Losartan; Male; Maleimides; Muscle Development; Muscle Fibers, Skeletal; Pressure; Protein Kinase C; Pyridines; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Tetrazoles; Vasoconstriction; Vasoconstrictor Agents

2016
Candesartan prevents resiniferatoxin-induced sensory small-fiber neuropathy in mice by promoting angiotensin II-mediated AT2 receptor stimulation.
    Neuropharmacology, 2017, Volume: 126

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Calcitonin Gene-Related Peptide; Diterpenes; Ganglia, Spinal; Imidazoles; Male; Mice; Mice, Knockout; Neuroprotective Agents; Pyridines; Ramipril; Receptor, Angiotensin, Type 2; Sensory Receptor Cells; Small Fiber Neuropathy; Substance P; Tetrazoles

2017
Neuroprotective effect of angiotensin II type 2 receptor stimulation in vincristine-induced mechanical allodynia.
    Pain, 2018, Volume: 159, Issue:12

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Antineoplastic Agents, Phytogenic; Benzimidazoles; Biphenyl Compounds; Disease Models, Animal; Diterpenes; Ganglia, Spinal; Hyperalgesia; Imidazoles; Male; Mice; Motor Activity; Neural Conduction; Neurons; Neuroprotective Agents; Neurotoxins; Nociception; Pyridines; Sciatic Nerve; Skin; Tetrazoles; Vincristine

2018