candesartan has been researched along with losartan in 227 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 33 (14.54) | 18.2507 |
| 2000's | 127 (55.95) | 29.6817 |
| 2010's | 62 (27.31) | 24.3611 |
| 2020's | 5 (2.20) | 2.80 |
| Authors | Studies |
|---|---|
| Furukawa, Y; Inada, Y; Kato, T; Kohara, Y; Kubo, K; Naka, T; Nishikawa, K; Shibouta, Y; Yoshimura, Y | 1 |
| Goldberg, MR; Greenlee, WJ; Irvin, JD; Prendergast, K; Smith, RD; Timmermans, PB; Wexler, RR | 1 |
| Imamiya, E; Inada, Y; Kohara, Y; Kubo, K; Naka, T; Wada, T | 1 |
| Funakoshi, J; Kakumoto, M; Okumura, K; Sakaeda, T; Takara, K; Tanigawara, Y | 1 |
| Berellini, G; Cruciani, G; Mannhold, R | 1 |
| Balakumar, P; Bali, A; Bansal, G; Bansal, Y; Kaur, G; Saggu, JS; Sharma, A; Singh, M; Sugumaran, M | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Bansal, G; Bansal, Y; Shah, DI; Sharma, M; Singh, M | 1 |
| Bansal, G; Bansal, Y; Kaur, A; Kaur, N; Shah, DI; Singh, M | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Giridhar, R; Murumkar, P; Naik, P; Yadav, MR | 1 |
| Fukami, T; Hosomi, H; Iwamura, A; Nakajima, M; Yokoi, T | 1 |
| Abad-Santos, F; Cabaleiro, T; López-Rodríguez, R; Novalbos, J; Ochoa, D; Prieto-Pérez, R; Román, M; Talegón, M; Wojnicz, A | 1 |
| Åqvist, J; Gutiérrez-de-Terán, H; Hallberg, A; Sallander, J; Wallinder, C | 1 |
| Bernhardt, G; Biselli, S; Buschauer, A; Cabrele, C; Einsiedel, J; Gmeiner, P; Hübner, H; Keller, M; Kuhn, KK; Mollereau, C; Svobodová, J; Vanderheyden, PM; Wifling, D | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Benachour, N; Vanderheyden, PML | 1 |
| Gust, R; Obexer, P; Salcher, S; Schoepf, AM | 1 |
| Foster, H; Foster, R; Philippou, H; Wilson, C | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Abe, J; Kurokawa, K; Ohno, M; Schwartz, SM; Taguchi, J | 1 |
| Inada, Y; Kohara, Y; Kubo, K; Naka, T; Nishikawa, K; Noda, M; Ojima, M; Sanada, T; Shibouta, Y; Wada, T | 1 |
| Fujimoto, M; Hara, M; Itazaki, K; Itoh, N | 1 |
| Bunting, MW; Widdop, RE | 1 |
| Li, XC; Widdop, RE | 1 |
| Inada, Y; Kubo, K; Nishikawa, K; Ojima, M; Sanada, T; Shibouta, Y; Wada, T | 1 |
| Magga, J; Marttila, M; Ruskoaho, H; Vuolteenaho, O | 1 |
| Jin, D; Miyazaki, M; Oka, Y; Shiota, N; Song, K; Takai, S | 1 |
| Champion, HC; Czapla, MA; Kadowitz, PJ | 1 |
| Chen, X; Fogo, A; Ichikawa, I; Inagami, T; Matsusaka, T; Niimura, F; Nishimura, H; Okubo, S; Tsuchida, S; Utsunomiya, H | 1 |
| Dendorfer, A; Dominiak, P; Raasch, W; Tempel, K | 2 |
| Bunt, T | 1 |
| Ardaillou, R | 1 |
| Ardaillou, R; Chansel, D; Chatziantoniou, C; Dussaule, JC | 1 |
| Rydén, L; Shimizu, M; Sjöquist, PO; Wang, QD | 1 |
| Goligorsky, MS; Kornfeld, M; Moore, LC; Thorup, C | 1 |
| Morsing, P | 1 |
| De Backer, JP; Fierens, F; Vanderheyden, PM; Vauquelin, G | 1 |
| Harris, PJ; Hiranyachattada, S; Smart, ML | 1 |
| Hiwada, K | 1 |
| Abrahamsson, T; Adler, G; Brandt-Eliasson, U; Karp, L; Morsing, P; Ohlson, K; Renberg, L; Sjöquist, PO | 1 |
| Kirk, JK | 1 |
| De Backer, JP; Fierens, FL; Vanderheyden, PM; Vauquelin, G | 1 |
| Garcha, RS; Hughes, AD; Sever, PS | 1 |
| Kaplan, NM | 1 |
| Sjöquist, PO; Wang, QD | 1 |
| Riegger, GA | 1 |
| Spence, JD | 1 |
| van Veldhuisen, DJ; Voors, AA | 1 |
| Ardaillou, R; Chansel, D; Llorens-Cortes, C; Vandermeersch, S | 1 |
| Cice, G; Di Benedetto, A; Ferrara, L; Iacono, A; Russo, PE; Tagliamonte, E | 1 |
| Benedict, C; Bunt, AM; Conlin, PR; Ribeiro, AB; Saito, I; Spence, JD; Williams, B | 1 |
| Casado, S; Farré, J; Gómez, J; Jiménez, A; López-Blaya, A; López-Farré, A; Montón, M; Núñez, A; Sánchez de Miguel, L; Zalba, LR | 1 |
| Kiukaanniemi, K; Pelkonen, O; Taavitsainen, P | 1 |
| Grossman, E; Messerli, FH; Neutel, JM | 1 |
| Howes, L; Wong, W | 1 |
| Meredith, PA | 1 |
| Elliott, WJ | 1 |
| Belz, GG; Breithaupt-Grögler, K; Fuchs, B; Herrmann, V; Malerczyk, C; Mutschler, E; Roll, S; Spahn-Langguth, H | 1 |
| Fierens, FL; Vanderheyden, PM; Vauquelin, G | 1 |
| Badguet, JP; Mallion, JM | 1 |
| Barragan, J; Bernhardi, DC; Bunt, T; Cabrera, WJ; Dumortier, T; Grossman, E; Jacovides, A; Jelakovic, B; Manolis, AJ; Matadamas, N; Mejia, AD; Mendiola, A; Smith, RD; Watanabe, LA; Woo, KS; Zhu, JR | 1 |
| De Backer, JP; Fierens, FL; Morsing, P; Vanderheyden, PM; Vauquelin, G | 1 |
| Goulet, J; Martineau, P | 1 |
| Vidt, DG | 1 |
| Arriero, MM; Cabestrero, F; Casado, S; de Miguel, LS; Farré, J; García, R; García-Colis, E; Gómez, J; Jiménez, AM; López-Farré, A; Montón, M; Núñez, A; Rico, L | 1 |
| DiBona, GF; Jones, SY | 2 |
| Ramahi, TM | 1 |
| Messerli, FH | 2 |
| Abe, I; Kagiyama, S; Lin, Y; Matsumura, K; Tsuchihashi, T | 1 |
| Casado, S; Gómez, J; Jiménez, A; Lopez-Bloya, A; López-Farré, A; Montón, M; Núñez, A; Rico, L; Sánchez de Miguel, L | 1 |
| Berlowitz, MS; Colombo, PC; Ennezat, PV; Hankins, SR; Latif, F; Le Jemtel, TH; Moskowitz, R; Tandon, S | 1 |
| McMurray, JJ | 1 |
| Magometschnigg, D | 1 |
| Fruhwald, FM; Kickenweiz, E; Klein, W; Zweiker, R | 1 |
| Schernthaner, G; Schnack, C | 1 |
| Cook, JL; Re, RN; Zhang, Z | 1 |
| Bassenge, E; Schwemmer, M; Sommer, O | 1 |
| Brunner, HR; Burnier, M; Centeno, C; Maillard, MP; Nussberger, J; Würzner, G | 1 |
| Achard, JM; Allard, J; Dalmay, F; Fournier, A; Mazouz, H; Pesteil, F | 1 |
| Morsing, P; Vauquelin, G | 1 |
| Bell, PD; Peti-Peterdi, J; Warnock, DG | 1 |
| Casado, S; Gómez, J; Jiménez, A; López-Blaya, A; López-Farré, A; Montón, M; Núñez, A; Uriarte, AC; Velasco, S; Zalba, LR | 1 |
| Rapi, J | 1 |
| Fakouhi, K; He, W; Krause, S; Krum, H; Nolly, H; Roniker, B; Workman, D | 1 |
| Andersson, OK; Elmfeldt, D; Friberg, PR; Fridman, KU; Wysocki, M | 1 |
| Edvinsson, L; Malmsjö, M; Pantev, E; Stenman, E; Wackenfors, A | 1 |
| Elmfeldt, D; Meredith, P; Olofsson, B | 1 |
| Alvarez, A; Fernández-Calotti, P; Gamberale, R; Geffner, JR; Giordano, M; Nahmod, KA; Nahmod, V; Raiden, S; Salamone, G; Vermeulen, ME | 1 |
| Mancini, GB | 1 |
| Fukuda, N; Onose, Y; Sakabe, K; Shinohara, H; Soeki, T; Tamura, Y | 1 |
| Chiba, S; Inada, Y; Nakane, T | 1 |
| DiBona, GF | 1 |
| Boonstra, PW; Buikema, H; Lübeck, RH; van Buiten, A; van Gilst, WH; van Veldhuisen, DJ; Voors, AA; Wagenaar, LJ | 1 |
| Head, GA; Mayorov, DN | 1 |
| Hunyady, L; Kersemans, V; Le, MT; Szaszák, M; Vanderheyden, PM; Vauquelin, G | 1 |
| Kinugawa, K; Nagai, R; Takahashi, T | 1 |
| Schieffer, B; Schmidt, B | 1 |
| Alföldi, S | 1 |
| Terra, SG | 1 |
| Buikema, H; de Zeeuw, D; Gschwend, S; Henning, RH; Pinto, YM; van Gilst, WH | 1 |
| Preobrazhenskiĭ, DV; Sidorenko, BA; Stetsenko, TM; Tarykina, EV; Tsurko, VV | 1 |
| Kim, S | 1 |
| Hashimoto, R; Kawahara, S; Matsuzaki, M; Umemoto, S | 1 |
| Temple, RJ | 1 |
| Jermendy, G; Matos, L; Winkler, G | 2 |
| Dominiak, P; Häuser, W | 1 |
| Latini, R; Maggioni, AP; Masson, S; Staszewsky, L | 1 |
| Hayashi, K; Homma, K; Kanda, T; Matsuda, H; Saruta, T; Takamatsu, I; Tatematsu, S; Wakino, S; Yoshioka, K | 1 |
| Gogonea, C; Karnik, SS; Noda, K; Saad, Y; Takezako, T | 1 |
| Edvinsson, L; Stenman, E | 1 |
| Ivanova, NA; Preobrazhenskiĭ, DV; Sidorenko, BA; Soplevenko, AV; Stetsenko, TM | 1 |
| Anzai, T; Hashimoto, K; Himeno, H; Imai, K; Kawana, M; Kitakaze, M; Koretsune, Y; Maruyama, S; Masaoka, Y; Matsubara, H; Matsuoka, T; Miyao, Y; Miyatake, K; Miyauchi, T; Nakamura, Y; Nomura, F; Okamoto, H; Ozono, K; Sekiya, M; Shinohara, H; Shintani, U; Shiraki, T; Takaoka, H; Tsutamoto, T; Yasumura, Y; Yokoya, K; Yokoyama, H | 1 |
| Alhenc-Gelas, F; Bergaya, S; Bloch-Faure, M; Boulanger, CM; Dong, Y; Hilgers, RH; Inagami, T; Lévy, BI; Meneton, P | 1 |
| Ahn, JY; Ahn, TH; Chung, WJ; Han, SH; Jin, DK; Kang, WC; Kim, HS; Koh, KK; Park, GS; Shin, EK | 1 |
| Iigaya, K; Kumagai, H; Onami, T; Saruta, T; Takimoto, C | 1 |
| Arakawa, K | 1 |
| Hayashi, K; Iwamoto, K; Kizawa, Y; Koike, K; Kusama, T; Murakami, H; Ohsawa, M; Ohuchi, N; Sano, M; Taniguchi, Y | 1 |
| Lindholm, LH | 1 |
| Dendorfer, A; Dominiak, P; Raasch, W; Ziegler, A | 1 |
| Stumpe, KO | 1 |
| Chen, K; Joseph, J; Joseph, L; Li, D; Mehta, JL | 1 |
| Komuro, I; Kuwabara, Y | 1 |
| Ishikawa, A; Kawabe, K; Kitamura, T; Ohta, N; Ozono, S | 1 |
| Erhardt, LR | 1 |
| Kanda, H; Kubo, K; Mimura, T; Sato, K; Tateishi, S; Yamamoto, K; Yonezumi, A | 1 |
| Becker, BN; Chiriva-Internati, M; Djamali, A; Hullett, DA; Jacobson, LM; Muehrer, RJ; Sprague, J; Thekkumkara, TJ; Weidanz, JA; Wittman, V | 1 |
| Asayama, K; Hashimoto, J; Imai, Y; Kikuya, M; Metoki, H; Nishimura, T; Ohkubo, T; Totsune, K | 1 |
| Barrios Alonso, V; Calderón Montero, A; Escobar Cervantes, C | 1 |
| Horio, T; Inenaga, T; Kamide, K; Kawano, Y; Kubota, Y; Ogata, C; Sasaki, O; Sato, H; Suzuki, Y; Takiuchi, S | 1 |
| Ishimitsu, T; Matsuoka, H; Minami, J | 1 |
| Baines, D; Isaacs, S; Opie, LH; Rayner, BL; Trinder, YA | 1 |
| Kanno, Y; Shoda, J; Suzuki, H | 1 |
| Cheung, BM | 1 |
| Cesolari, JA; Laudanno, OM | 1 |
| Leary, WP; Reyes, AJ | 1 |
| Koyabu, N; Kuwano, M; Murakami, H; Nakamura, T; Ohtani, H; Satoh, H; Sawada, Y; Tsujimoto, M; Uchiumi, T; Ushigome, F; Yamashita, F | 1 |
| Kirby, M; Pearmain, H; Ramsbottom, T; Usher-Smith, JA | 1 |
| Abitbol, C; Chandar, J; Montané, B; Zilleruelo, G | 1 |
| Miyagi, R; Okamoto, H; Sugiyama, K; Yayama, K | 1 |
| Andoh, Y; Dong, J; Fujii, S; Furumoto, T; Imagawa, S; Ishimori, N; Ohmura, K; Ohmura, Y; Sato, Y; Tsutsui, H | 1 |
| Behlouli, H; Hudson, M; Humphries, K; Pilote, L; Sheppard, R; Tu, JV | 1 |
| Abe, C; Akashiba, A; Ishimitsu, T; Kameda, T; Matsuoka, H; Minami, J; Takahashi, T | 1 |
| Akazawa, H; Komuro, I; Kudo, Y | 1 |
| Murakami, M; Nakagiri, A; Sunamoto, M | 1 |
| Fujita, T; Gohchi, K; Shimosawa, T; Yatomi, Y | 1 |
| Belsey, JD | 1 |
| Kirby, M; Pearmain, H; Ramsbottom, T; Usher-Smith, J | 1 |
| Aitio, O; Alonen, A; Finel, M; Jansson, J; Kallonen, S; Kiriazis, A; Kostiainen, R | 1 |
| Kageyama, S | 1 |
| Dal Pan, GJ; Governale, LA; Hammad, TA; McAdams, MA; Swartz, L | 1 |
| Araki, R; Ikeda, N; Inoue, T; Kanno, Y; Shoda, J; Sugahara, S; Suzuki, H; Takenaka, T | 1 |
| Hamada, T; Hisatome, I; Hosoya, T; Hosoyamada, M; Ichida, K; Igawa, O; Mizuta, E; Ninomiya, H; Ohtahara, A; Shigamasa, C; Sonoyama, K; Sugihara, S; Yamamoto, Y; Yanagihara, K | 1 |
| Alonen, A; Finel, M; Kostiainen, R | 1 |
| Georgescu, EF | 1 |
| Hamamoto, Y; Honjo, S; Ikeda, H; Koshiyama, H; Nabe, K; Wada, Y | 1 |
| Hatzitolios, A; Ntaios, G; Savopoulos, C | 1 |
| Frohlich, ED; Susic, D; Zhou, X | 1 |
| Kuji, T; Masuda, S; Okano, Y; Tamura, K; Tochikubo, O; Umemura, S | 1 |
| Falvey, H; Lowy, A; Müller, E; Nixon, RM | 1 |
| Bhuiyan, MA; Hossain, M; Ishiguro, M; Miura, S; Nagatomo, T; Nakamura, T; Ozaki, M | 1 |
| Casselbrant, A; Edebo, A; Fändriks, L; Hallersund, P; Helander, HF; Jönson, C; Spak, E | 1 |
| Ando, C; Inoue, Y; Kodama, S; Mihara, H; Miyoshi, K; Niimura, H; Okamura, K; Sumi, S; Tojyo, H; Tsuchiya, Y; Urata, H; Yamanouchi, Y | 1 |
| Bodegard, J; Hasvold, P; Kjeldsen, SE; Olsson, U; Russell, D; Stålhammar, J | 1 |
| Kamiyama, E; Mikkaichi, T; Nakai, D; Okazaki, O; Okudaira, N | 1 |
| Masuda, S; Okano, Y; Ozawa, M; Tamura, K; Tochikubo, O; Umemura, S | 1 |
| Neldam, S | 1 |
| McInnes, GT; Meredith, PA; Murray, LS | 1 |
| McMurray, JJ; Swedberg, K | 1 |
| Bhuiyan, MA; Hossain, M; Nagatomo, T; Nakamura, T; Ozaki, M | 1 |
| Hamada, T; Hirai, M; Hisatome, I; Igawa, O; Kato, M; Kondo, T; Mizuta, E; Ninomiya, H; Shigemasa, C; Yamada, K; Yamamoto, Y | 1 |
| Bodegard, J; Hasvold, P; Henriksson, M; Kjeldsen, S; Levin, LÅ; Russell, D; Stålhammar, J | 1 |
| Suzuki, H; Takenaka, T | 1 |
| Arsenault, J; Cabana, J; Escher, E; Guillemette, G; Lanthier, L; Lavigne, P; Leduc, R; Lehoux, J | 1 |
| Naviglio, S; Pirozzi, F | 1 |
| Fujiwara, N; Koide, H; Nakamura, T; Sato, E; Sugaya, T; Ueda, Y | 1 |
| Ge, J; Gong, H; Komuro, I; Li, L; Lin, L; Wu, J; Zhou, N; Zou, Y | 1 |
| Bonde, MM; Erikstrup, N; Hansen, JL; Haunsø, S; Lyngsø, C; Nielsen, MS; Olsen, KB; Sheikh, SP; Speerschneider, T | 1 |
| Benson, L; Dahlström, U; Edner, M; Eklind-Cervenka, M; Lund, LH; Rosenqvist, M | 1 |
| Dodson, P; Hobbs, FR; Sjølie, AK | 1 |
| Bodalia, PN; Grosso, AM; Hingorani, AD; Macallister, RJ; Moon, JC; Scott, MA | 1 |
| Julius, S; Pitt, B | 1 |
| Minhas, R | 1 |
| Bodegard, J; Hasvold, P; Kjeldsen, SE; Russell, D; Stålhammar, J; Thuresson, M | 1 |
| Hillfinger, J; Jin, X; Kim, JS; Koga, H; Larsen, SD; Lipka, E; Lucas, PC; Okawada, M; Showalter, HD; Teitelbaum, DH; Turbiak, AJ | 1 |
| Groenwold, RH; Rutten, FH | 1 |
| Fruhwald, F; Pieske, B | 1 |
| Kaplan, N | 1 |
| Benetis, NP; Christodouleas, D; Fotakis, C; Gili, A; Kritsi, E; Mavromoustakos, T; Papadopoulos, MG; Reis, H; Zervou, M; Zoumpoulakis, P | 1 |
| Chang, CH; Lai, MS; Lin, JW; Wu, LC | 1 |
| Aparasu, RR; Ashton, CM; Chen, H; Desai, RJ; Deswal, A; Johnson, ML; Mehta, HB; Morgan, RO | 1 |
| Hasegawa, H; Kameda, Y; Kobayashi, Y; Komuro, I; Kubota, A; Takano, H | 1 |
| Iwao, H; Izumi, Y; Kita, H; Osada-Oka, M; Sato, T; Yagi, S | 1 |
| Hviid, A; Pasternak, B; Svanström, H | 1 |
| Joffe, MM; Yang, W | 1 |
| Abbas, H; Ali, R; Geirsson, A; Hashim, S; Li, W; Sanchez, JA; Singh, M; Tellides, G | 1 |
| Aoyama, T; Goto, M; Goto, N; Hiei, K; Iwasa, M; Kawai, N; Kida, K; Kobayashi, H; Kojima, S; Minagawa, T; Minatoguchi, S; Oda, M; Sugishita, F; Takai, K; Tanaka, R; Watanabe, I; Yamamoto, N; Yasue, T | 1 |
| Inamdar, MN; Kulkarni, C; Kulkarni, KS; Moinuddin, G | 1 |
| Antoniou, T; Camacho, X; Gomes, T; Juurlink, DN; Mamdani, MM; Yao, Z | 1 |
| Caffrey, JL; Chang, CH; Lai, MS; Lin, JW; Wu, LC | 1 |
| Miyake, S; Nagai, N; Narimatsu, T; Ozawa, Y; Tsubota, K | 1 |
| Komano, H; Liu, J; Liu, S; Maeda, T; Tanabe, C; Zou, K | 1 |
| Imai, K; Iwazaki, A; Nakagawa, M; Nakanishi, K; Takahashi, K; Tamezane, Y; Tanaka, K | 1 |
| Gislason, GH; Kristensen, SL; Køber, L; Lamberts, M; Selmer, C; Torp-Pedersen, C; von Kappelgaard, LM | 1 |
| Arksey, N; Beanlands, RS; DaSilva, JN; deKemp, RA; Hachem, M; Hadizad, T; Ismail, B; Valdivia, AC | 1 |
| Boerwinkle, E; Chapman, AB; Cooper-DeHoff, RM; Donner, KM; Frau, F; Glorioso, N; Glorioso, V; Gong, Y; Gums, JG; Hiltunen, TP; Johnson, JA; Kontula, KK; Ripatti, S; Saarela, J; Salvi, E; Sarin, AP; Turner, ST; Zaninello, R | 1 |
| Artur de laVillarmois, E; Baiardi, G; Basmadjian, OM; Bregonzio, C; Marchese, NA; Perez, MF | 1 |
| Asayama, K; Haga, T; Hosaka, M; Imai, Y; Inoue, R; Kikuya, M; Mano, N; Metoki, H; Murakami, T; Obara, T; Ohkubo, T; Satoh, M | 1 |
| Clifford, PS; Davis, MJ; Hill, MA; Hong, K; Hong, Z; Meininger, GA; Sun, Z; Yang, Y; Zhao, G | 1 |
| Brolund, L; Brolund-Spaether, K; Cascorbi, I; Culman, J; Gohlke, P; Jacob, T; Schuster, SO; Zhao, Y | 1 |
| Ali, SS; Gazzaz, ZJ; Ibraheem, MS; Murad, HA | 1 |
| Blais, C; Guénette, L; Hamel, D; Leclerc, J; Poirier, P; Rochette, L | 1 |
| Busby, J; Cardwell, CR; Hughes, C; Johnston, BT; McMenamin, Ú; Spence, A | 1 |
| Jóźwiak, K; Kocki, T; Targowska-Duda, KM; Turski, WA; Wnorowski, A; Zakrocka, I | 1 |
| Casselbrant, A; Edebo, A; Fändriks, L; Hallersund, P; Spak, E | 1 |
| Dantas, ASCL; de Lima, PC; de Souza, MN; Ferreira, LODS; Lima, MED; Maranho, RLDN; Monteiro, MA; Novotny, TS; Ochs, SM; Santana, DS | 1 |
| Bradley, M; Eworuke, E; Hedenmalm, K; Kurz, X; Lee, H; Quinten, C | 1 |
57 review(s) available for candesartan and losartan
| Article | Year |
|---|---|
Nonpeptide angiotensin II receptor antagonists: the next generation in antihypertensive therapy.
Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Humans; Receptors, Angiotensin; Structure-Activity Relationship | 1996 |
Angiotensin II receptor type 1 (AT1) selective nonpeptidic antagonists--a perspective.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Antihypertensive Agents; Humans; Losartan | 2010 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Influence of the cellular environment on ligand binding kinetics at membrane-bound targets.
Topics: Angiotensin II Type 1 Receptor Blockers; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Humans; Kinetics; Ligands; Protein Binding; Receptor, Angiotensin, Type 1; Receptors, Cell Surface; Signal Transduction | 2017 |
Angiotensin II receptors.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Endothelium; Humans; Imidazoles; Kidney; Losartan; Peptide Fragments; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles | 1999 |
Mesangial AT1 receptors: expression, signaling, and regulation.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Binding, Competitive; Biphenyl Compounds; Cells, Cultured; Gene Expression Regulation; Glomerular Mesangium; Humans; Losartan; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Signal Transduction; Tetrazoles | 1999 |
Candesartan: a new-generation angiotensin II AT1 receptor blocker: pharmacology, antihypertensive efficacy, renal function, and renoprotection.
Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Disease Models, Animal; Hemodynamics; Humans; Hypertension; Irbesartan; Kidney; Losartan; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles | 1999 |
[Comparison with other antihypertensive drugs, especially with ACEI].
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Humans; Hypertension; Losartan; Tetrazoles | 1999 |
Angiotensin-II receptor antagonists: their place in therapy.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Clinical Trials as Topic; Drug Administration Schedule; Drug Interactions; Heart Failure; Humans; Hypertension; Irbesartan; Losartan; Renin-Angiotensin System; Telmisartan; Tetrazoles; Valine; Valsartan | 1999 |
Angiotensin II receptor antagonists in the treatment of hypertension.
Topics: Algorithms; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Humans; Hypertension; Irbesartan; Losartan; Receptors, Angiotensin; Telmisartan; Tetrazoles; Valine; Valsartan | 1999 |
[ACE inhibitors or AT1 receptor antagonists?].
Topics: Age Factors; Aged; Angiotensin I; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Captopril; Clinical Trials as Topic; Death, Sudden, Cardiac; Enalapril; Heart Failure; Humans; Losartan; Prodrugs; Prognosis; Randomized Controlled Trials as Topic; Risk Factors; Tetrazoles; Time Factors | 1999 |
Angiotensin II antagonists for hypertension: are there differences in efficacy?
Topics: Angiotensin II; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Humans; Hypertension; Irbesartan; Losartan; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan | 2000 |
Angiotensin II receptor blockers: equal or preferred substitutes for ACE inhibitors?
Topics: Acrylates; Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Drug Therapy, Combination; Heart; Humans; Hypertension; Imidazoles; Irbesartan; Kidney; Losartan; Renin-Angiotensin System; Telmisartan; Tetrazoles; Thiophenes | 2000 |
Angiotensin receptor antagonists.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Humans; Hypertension; Irbesartan; Losartan; Telmisartan; Tetrazoles | 2000 |
Therapeutic trials comparing angiotensin converting enzyme inhibitors and angiotensin II receptor blockers.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Humans; Hypertension; Losartan; Randomized Controlled Trials as Topic; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2000 |
Putting the efficacy of candesartan cilexetil into perspective: a review of new comparative data.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cattle; Cerebellum; Circadian Rhythm; Female; Heart; Humans; Hypertension; In Vitro Techniques; Irbesartan; Kinetics; Losartan; Male; Middle Aged; Prodrugs; Rabbits; Randomized Controlled Trials as Topic; Receptors, Angiotensin; Renin; Tetrazoles; Time Factors | 2000 |
New competition in the realm of renin-angiotensin axis inhibition; the angiotensin II receptor antagonists in congestive heart failure.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Clinical Trials as Topic; Heart Failure; Humans; Losartan; Meta-Analysis as Topic; Renin-Angiotensin System; Tetrazoles | 2001 |
Expanded role for ARBs in cardiovascular and renal disease? Recent observations have far-reaching implications.
Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biological Availability; Biphenyl Compounds; Cardiovascular Diseases; Humans; Imidazoles; Irbesartan; Kidney Diseases; Losartan; Metabolic Clearance Rate; Patient Selection; Renin-Angiotensin System; Telmisartan; Tetrazoles; Thiophenes; Treatment Outcome; Valine; Valsartan | 2001 |
Angiotensin II AT(1) receptor antagonists and platelet activation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Coronary Disease; Coronary Thrombosis; Humans; Losartan; P-Selectin; Platelet Activation; Platelet Aggregation; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Thromboxane; Tetrazoles; Thrombosis; Thromboxane A2; Valine; Valsartan | 2001 |
Angiotensin receptor blockers for chronic heart failure and acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Drug Therapy, Combination; Heart Failure; Humans; Losartan; Models, Cardiovascular; Myocardial Infarction; Randomized Controlled Trials as Topic; Tetrazoles | 2001 |
[Angiotensin receptor blockers--significance for the therapy of hypertension].
Topics: Acrylates; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Austria; Benzimidazoles; Benzoates; Biphenyl Compounds; Humans; Hypertension; Imidazoles; Losartan; Prodrugs; Telmisartan; Tetrazoles; Therapeutic Equivalency; Thiophenes; Valine; Valsartan | 2001 |
[Angiotensin I receptor blockers for heart failure].
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Austria; Benzimidazoles; Biphenyl Compounds; Contraindications; Cough; Drug Therapy, Combination; Heart Failure; Humans; Losartan; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles; Valine; Valsartan | 2001 |
[Angiotensin II type-1 receptor antagonists and diabetes mellitus].
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Diabetes Complications; Diabetic Angiopathies; Diabetic Nephropathies; Drug Therapy, Combination; Humans; Hypertension; Losartan; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles | 2001 |
How can the differences among AT1-receptor antagonists be explained?
Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Humans; Kinetics; Losartan; Models, Biological; Models, Chemical; Protein Binding; Receptor, Angiotensin, Type 1; Tetrazoles | 2001 |
[Irbesartan: a new possibility in the treatment of hypertension].
Topics: Acrylates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Atenolol; Benzimidazoles; Benzoates; Biological Availability; Biphenyl Compounds; Controlled Clinical Trials as Topic; Drug Administration Schedule; Enalapril; Half-Life; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan | 2002 |
The relationships between dose and antihypertensive effect of four AT1-receptor blockers. Differences in potency and efficacy.
Topics: Adult; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Irbesartan; Losartan; Male; Randomized Controlled Trials as Topic; Receptor, Angiotensin, Type 1; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2002 |
Emerging role of angiotensin II type 1 receptor blockers for the treatment of endothelial dysfunction and vascular inflammation.
Topics: Acrylates; Aged; Antihypertensive Agents; Benzimidazoles; Biomarkers; Biphenyl Compounds; Coronary Artery Disease; Data Interpretation, Statistical; Diabetes Mellitus; E-Selectin; Endothelium, Vascular; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Tetrazoles; Thiophenes; Vasculitis | 2002 |
Central angiotensin modulation of baroreflex control of renal sympathetic nerve activity in the rat: influence of dietary sodium.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Baroreflex; Benzimidazoles; Bicuculline; Biphenyl Compounds; Blood Pressure; Brain; Cerebral Ventricles; Kidney; Losartan; Medulla Oblongata; Paraventricular Hypothalamic Nucleus; Rats; Renin; Renin-Angiotensin System; Sodium, Dietary; Sympathetic Nervous System; Tetrazoles | 2003 |
[Treatment for diastolic failure].
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Diastole; Heart Failure; Humans; Losartan; Practice Guidelines as Topic; Receptor, Angiotensin, Type 1; Tetrazoles | 2003 |
Angiotensin II AT1 receptor antagonists. Clinical implications of active metabolites.
Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Growth Hormone; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Models, Molecular; Receptor, Angiotensin, Type 1; Tetrazoles; Thiophenes; Thromboxane A2 | 2003 |
[Diurnal blood pressure control in the optimal treatment of hypertension].
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Circadian Rhythm; Humans; Hypertension; Irbesartan; Losartan; Telmisartan; Tetrazoles; Valine; Valsartan | 2003 |
[Angiotensin I receptor antagonist losartan. Part II. Effects in arterial hypertension and diabetic nephropathy].
Topics: Angiotensin I; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diastole; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Losartan; Meta-Analysis as Topic; Placebos; Prognosis; Randomized Controlled Trials as Topic; Sodium Chloride Symporter Inhibitors; Systole; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2003 |
Stroke prevention: is it possible? If so, which antihypertensive agent should be used?
Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cerebrovascular Circulation; Humans; Hypertension; Losartan; Rats; Rats, Inbred SHR; Stroke; Tetrazoles | 2003 |
[Angiotensin receptor blockers in chronic heart failure].
Topics: Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Double-Blind Method; Heart Failure; Humans; Hypertension; Japan; Losartan; Myocardial Infarction; Neurotransmitter Agents; Randomized Controlled Trials as Topic; Risk Factors; Tetrazoles; Valine; Valsartan; Ventricular Dysfunction, Left; Ventricular Remodeling | 2003 |
[Theoretical background of angiotensin II receptor blockade and its features in clinical pharmacology].
Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Humans; Imidazoles; Irbesartan; Losartan; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan | 2003 |
[Cardiologic and diabetologic aspects of therapy with angiotensin receptor blocking agents].
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Clinical Trials as Topic; Diabetes Complications; Heart Failure; Humans; Hypertension; Losartan; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan | 2003 |
Valsartan for the treatment of heart failure.
Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Clinical Trials as Topic; Drug Therapy, Combination; Heart Failure; Humans; Losartan; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2004 |
[Candesartan - a novel AT(1)-angiotensin receptor blocker: peculiarities of pharmacology and experience of use in arterial hypertension].
Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Diabetic Nephropathies; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Tetrazoles; Thiophenes; Valine; Valsartan | 2004 |
[Organ protection by angiotensin II receptor blockers].
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cognition Disorders; Heart Failure; Humans; Hypertension; Kidney Diseases; Losartan; Membrane Proteins; Mineralocorticoid Receptor Antagonists; Proteins; Proteinuria; Randomized Controlled Trials as Topic; Stroke; Tetrazoles | 2004 |
[Development of combined drugs (ARB and diuretics)].
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Clinical Trials as Topic; Diuretics; Drug Combinations; Drug Design; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Kidney Tubules, Proximal; Losartan; Olmesartan Medoxomil; Practice Guidelines as Topic; Renin-Angiotensin System; Sodium; Telmisartan; Tetrazoles | 2004 |
Olmesartan compared with other angiotensin II receptor antagonists: head-to-head trials.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Olmesartan Medoxomil; Randomized Controlled Trials as Topic; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2004 |
[Ace inhibitors and angiotensin II receptor antagonists for therapy of chronic heart failure].
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Clinical Trials as Topic; Enalapril; Heart Failure; Humans; Indoles; Lisinopril; Losartan; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan | 2005 |
A review of the current evidence for the use of angiotensin-receptor blockers in chronic heart failure.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Captopril; Drug Therapy, Combination; Drug Tolerance; Heart Failure; Humans; Losartan; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2005 |
[ARB II in chronic heart failure. Coincidences and divergences. Class effect?].
Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Chronic Disease; Heart Failure; Humans; Losartan; Systole; Tetrazoles; Valine; Valsartan | 2005 |
Therapeutic potential of angiotensin receptor blockers in hypertension.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Coronary Disease; Female; Humans; Hypertension; Losartan; Male; Meta-Analysis as Topic; Myocardial Infarction; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Survival Analysis; Tetrazoles; Valine; Valsartan | 2006 |
[Pharmocological therapeutics for chronic heart failure--how to use ARB (angiotensin receptor blocker].
Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Chronic Disease; Clinical Trials as Topic; Drug Therapy, Combination; Heart Failure; Humans; Losartan; Myocardial Infarction; Severity of Illness Index; Survival Rate; Tetrazoles; Valine; Valsartan | 2007 |
[Clinical trials of ACE inhibitors and ARB for treatment of patients with hypertension, heart failure, and diabetic nephropathy in Japan--special reference to the dosage schedule and adverse effects].
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Captopril; Cough; Diabetic Nephropathies; Heart Failure; Humans; Hypertension; Japan; Losartan; Randomized Controlled Trials as Topic; Tetrazoles | 2008 |
Angiotensin receptor blockers in the treatment of NASH/NAFLD: could they be a first-class option?
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Biphenyl Compounds; Fatty Liver; Humans; Insulin Resistance; Losartan; Metabolic Syndrome; Renin-Angiotensin System; Telmisartan; Tetrazoles | 2008 |
Valsartan vs. other angiotensin II receptor blockers in the treatment of hypertension: a meta-analytical approach.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Dose-Response Relationship, Drug; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Middle Aged; Prospective Studies; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2009 |
Choosing an angiotensin-receptor blocker: blood pressure lowering, cardiovascular protection or both?
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Cardiovascular Diseases; Humans; Hypertension; Losartan; Ramipril; Risk Factors; Telmisartan; Tetrazoles | 2010 |
Comparison of the efficacy of candesartan and losartan: a meta-analysis of trials in the treatment of hypertension.
Topics: Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Humans; Hypertension; Losartan; Randomized Controlled Trials as Topic; Tetrazoles | 2010 |
[Recent clinical evidences of RAS inhibitors on chronic kidney diseases].
Topics: Amides; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Chronic Disease; Clinical Trials as Topic; Drug Therapy, Combination; Evidence-Based Medicine; Fumarates; Kidney Diseases; Losartan; Tetrazoles; Valine; Valsartan | 2010 |
Does renin-angiotensin system blockade have a role in preventing diabetic retinopathy? A clinical review.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Clinical Trials as Topic; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Enalapril; Humans; Losartan; Renin-Angiotensin System; Tetrazoles | 2011 |
Comparative clinical- and cost-effectiveness of candesartan and losartan in the management of hypertension and heart failure: a systematic review, meta- and cost-utility analysis.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Clinical Trials as Topic; Cost-Benefit Analysis; Drug Costs; Female; Heart Failure; Humans; Hypertension; Losartan; Male; Middle Aged; Quality-Adjusted Life Years; Risk Factors; Tetrazoles; Young Adult | 2011 |
Effects of telmisartan, irbesartan, valsartan, candesartan, and losartan on cancers in 15 trials enrolling 138,769 individuals.
Topics: Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Benzoates; Biphenyl Compounds; Case-Control Studies; Double-Blind Method; Humans; Hypertension; Irbesartan; Losartan; Neoplasms; Randomized Controlled Trials as Topic; Telmisartan; Tetrazoles | 2011 |
A systematic review and meta-analysis of candesartan and losartan in the management of essential hypertension.
Topics: Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Humans; Hypertension; Losartan; Publication Bias; Regression Analysis; Tetrazoles; Treatment Outcome | 2011 |
Angiotensin receptor blockade and risk of cancer in type 2 diabetes mellitus: a nationwide case-control study.
Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Benzoates; Biphenyl Compounds; Case-Control Studies; Comorbidity; Diabetes Complications; Diabetes Mellitus, Type 2; Drug Administration Schedule; Female; Humans; Incidence; Logistic Models; Losartan; Male; Middle Aged; Neoplasms; Odds Ratio; Publication Bias; Risk Assessment; Risk Factors; Taiwan; Telmisartan; Tetrazoles | 2011 |
28 trial(s) available for candesartan and losartan
| Article | Year |
|---|---|
Candesartan cilexetil vs losartan.
Topics: Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Humans; Hypertension; Losartan; Tetrazoles | 1998 |
[Angiotensin-II receptor inhibitors in hemodialysed uremia patients with arterial hypertension: candesartan cilexitil versus losartan].
Topics: Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Combined Modality Therapy; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Renal Dialysis; Single-Blind Method; Tetrazoles; Time Factors; Uremia | 1999 |
Comparative pharmacodynamics and pharmacokinetics of candesartan and losartan in man.
Topics: Adult; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Chromatography, High Pressure Liquid; Cross-Over Studies; Double-Blind Method; Humans; Losartan; Male; Radioligand Assay; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles | 2000 |
Effects of losartan and candesartan monotherapy and losartan/hydrochlorothiazide combination therapy in patients with mild to moderate hypertension. Losartan Trial Investigators.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Tetrazoles | 2000 |
Dose-dependent blockade of the angiotensin II type 1 receptor with losartan in normal volunteers.
Topics: Adult; Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Female; Humans; Losartan; Male; Middle Aged; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Vasoconstrictor Agents | 2001 |
Comparative angiotensin II receptor blockade in healthy volunteers: the importance of dosing.
Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cross-Over Studies; Dose-Response Relationship, Drug; Humans; Irbesartan; Losartan; Male; Renin; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan | 2002 |
Efficacy of eplerenone added to renin-angiotensin blockade in hypertensive patients.
Topics: Abdominal Pain; Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Diarrhea; Double-Blind Method; Drug Therapy, Combination; Eplerenone; Female; Headache; Heart Rate; Humans; Hypertension; Irbesartan; Losartan; Male; Middle Aged; Patient Dropouts; Renin-Angiotensin System; Spironolactone; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2002 |
Influence of AT1 receptor blockade on blood pressure, renal haemodynamics and hormonal responses to intravenous angiotensin II infusion in hypertensive patients.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hypertension; Infusions, Intravenous; Losartan; Male; Middle Aged; Receptor, Angiotensin, Type 1; Renal Circulation; Renin; Tetrazoles; Valine; Valsartan | 2002 |
Differing anti-proteinuric action of candesartan and losartan in chronic renal disease.
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Female; Humans; Kidney Failure, Chronic; Losartan; Male; Middle Aged; Nitric Oxide; Perindopril; Proteinuria; Tetrazoles | 2003 |
Rationale for the use of combination angiotensin-converting enzyme inhibitor and angiotensin II receptor blocker therapy in heart failure.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Drug Synergism; Drug Therapy, Combination; Exercise Tolerance; Female; Heart Failure; Heart Function Tests; Humans; Losartan; Male; Middle Aged; Natriuretic Peptide, Brain; Receptors, Angiotensin; Renin; Tetrazoles; Valine; Valsartan | 2004 |
Comparison of effects of losartan, irbesartan, and candesartan on flow-mediated brachial artery dilation and on inflammatory and thrombolytic markers in patients with systemic hypertension.
Topics: Angiotensin II; Antihypertensive Agents; Benzimidazoles; Biomarkers; Biphenyl Compounds; Brachial Artery; Double-Blind Method; Female; Humans; Hypertension; Irbesartan; Losartan; Male; Middle Aged; Tetrazoles; Vasodilation | 2004 |
Inhibition of plasminogen activator inhibitor-1 by angiotensin II receptor blockers on cyclosporine-treated renal allograft recipients.
Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Creatinine; Cyclosporine; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Kidney Transplantation; Losartan; Male; Middle Aged; Nifedipine; Plasminogen Activator Inhibitor 1; Tetrazoles; Transplantation, Homologous | 2005 |
Effect of losartan versus candesartan on uric acid, renal function, and fibrinogen in patients with hypertension and hyperuricemia associated with diuretics.
Topics: Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Diuretics; Female; Fibrinogen; Follow-Up Studies; Glomerular Filtration Rate; Humans; Hypertension; Hyperuricemia; Losartan; Male; Tetrazoles; Treatment Outcome; Uric Acid | 2006 |
A five-year comparison of the renal protective effects of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in patients with non-diabetic nephropathy.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Chronic Disease; Creatinine; Female; Glomerular Filtration Rate; Glomerulonephritis; Humans; Indoles; Losartan; Male; Middle Aged; Prospective Studies; Renal Insufficiency; Tetrazoles | 2006 |
Platelet aggregability in patients with hypertension treated with angiotensin II type 1 receptor blockers.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Cardiovascular Diseases; Female; Humans; Hypertension; Light; Losartan; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Scattering, Radiation; Tetrazoles; Therapeutic Equivalency | 2007 |
Long-term efficacy of combination therapy with losartan and low-dose hydrochlorothiazide in patients with uncontrolled hypertension.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Tetrazoles; Treatment Outcome | 2007 |
Effectiveness of add-on low-dose diuretics in combination therapy for hypertension: losartan/hydrochlorothiazide vs. candesartan/amlodipine.
Topics: Aged; Amlodipine; Antihypertensive Agents; Asian People; Benzimidazoles; Biphenyl Compounds; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Japan; Losartan; Male; Middle Aged; Prospective Studies; Tetrazoles; Treatment Outcome | 2007 |
Effect of angiotensin receptor blockers on cardiovascular events in patients undergoing hemodialysis: an open-label randomized controlled trial.
Topics: Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Cardiovascular Diseases; Female; Humans; Incidence; Kidney Failure, Chronic; Losartan; Male; Middle Aged; Renal Dialysis; Tetrazoles; Valine; Valsartan | 2008 |
Olmesartan reduced microalbuminuria in Japanese subjects with type 2 diabetes.
Topics: Aged; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Asian People; Benzimidazoles; Benzoates; Biphenyl Compounds; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Telmisartan; Tetrazoles; Valine; Valsartan | 2009 |
Effects of angiotensin II receptor blockers on relationships between 24-hour blood pressure, autonomic function, and health-related QOL.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Autonomic Nervous System; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Circadian Rhythm; Dose-Response Relationship, Drug; Female; Health Surveys; Heart Rate; Humans; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Quality of Life; Telmisartan; Tetrazoles; Valine; Valsartan | 2009 |
Additive antihypertensive and antihypertrophic effects of long-acting Ca blockers in uncontrolled hypertensive patients with angiotensin-receptor blocker based treatment.
Topics: Aged; Amlodipine; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Drug Therapy, Combination; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Nifedipine; Tetrazoles | 2009 |
Effects of angiotensin II receptor blockers on the relationships between ambulatory blood pressure and anti-hypertensive effects, autonomic function, and health-related quality of life.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Female; Heart Rate; Humans; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Quality of Life; Sympathetic Nervous System; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2009 |
Effects of a low-dose antihypertensive diuretic in combination with losartan, telmisartan, or candesartan on serum urate levels in hypertensive patients.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Glucose; Diuretics; Double-Blind Method; Female; Humans; Hypertension; Lipids; Losartan; Male; Middle Aged; Telmisartan; Tetrazoles; Uric Acid | 2010 |
Renoprotective Effects of Various Angiotensin II Receptor Blockers in Patients with Early-Stage Diabetic Nephropathy.
Topics: Adult; Aged; Angiotensin Receptor Antagonists; Benzimidazoles; Benzoates; Biphenyl Compounds; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Fatty Acid-Binding Proteins; Female; Humans; Imidazoles; Losartan; Male; Middle Aged; Telmisartan; Tetrazoles; Treatment Outcome | 2010 |
Effect of switching from telmisartan, valsartan, olmesartan, or losartan to candesartan on morning hypertension.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Asian People; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Female; Humans; Hypertension; Imidazoles; Japan; Losartan; Male; Middle Aged; Prospective Studies; Telmisartan; Tetrazoles; Valine; Valsartan | 2012 |
Comparative effect of candesartan and amlodipine, and effect of switching from valsartan, losartan, telmisartan and olmesartan to candesartan, on early morning hypertension and heart rate.
Topics: Aged; Amlodipine; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Drug Substitution; Female; Heart Rate; Humans; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Prospective Studies; Telmisartan; Tetrazoles; Valine; Valsartan | 2013 |
Pharmacogenomics of hypertension: a genome‐wide, placebo‐controlled cross‐over study, using four classes of antihypertensive drugs.
Topics: Adult; Aldehyde Oxidoreductases; Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Bisoprolol; Blood Pressure Monitoring, Ambulatory; Chloride Channels; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Essential Hypertension; Finland; Genome-Wide Association Study; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Membrane Proteins; Meta-Analysis as Topic; Microfilament Proteins; Middle Aged; Mutation, Missense; Pharmacogenetics; Polymorphism, Single Nucleotide; Severity of Illness Index; Tetrazoles; Treatment Outcome | 2015 |
The human duodenal mucosa harbors all components for a local renin angiotensin system.
Topics: Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Duodenum; Female; Gastrointestinal Motility; Humans; Intestinal Mucosa; Losartan; Male; Middle Aged; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Renin-Angiotensin System; Tetrazoles; Young Adult | 2019 |
142 other study(ies) available for candesartan and losartan
| Article | Year |
|---|---|
Nonpeptide angiotensin II receptor antagonists. Synthesis and biological activity of potential prodrugs of benzimidazole-7-carboxylic acids.
Topics: Administration, Oral; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biological Availability; Biphenyl Compounds; Male; Prodrugs; Rats; Rats, Sprague-Dawley; Tetrazoles | 1993 |
Synthesis and angiotensin II receptor antagonistic activities of benzimidazole derivatives bearing acidic heterocycles as novel tetrazole bioisosteres.
Topics: Angiotensin Receptor Antagonists; Benzimidazoles; Magnetic Resonance Spectroscopy; Spectrophotometry, Infrared | 1996 |
Interaction of digoxin with antihypertensive drugs via MDR1.
Topics: Animals; Antihypertensive Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cells, Cultured; Digoxin; Drug Interactions; Humans; Time Factors | 2002 |
Pharmacophore, drug metabolism, and pharmacokinetics models on non-peptide AT1, AT2, and AT1/AT2 angiotensin II receptor antagonists.
Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Binding Sites; Biphenyl Compounds; Kinetics; Losartan; Models, Molecular; Molecular Conformation; Oxidation-Reduction; Pharmaceutical Preparations; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Structure-Activity Relationship; Tetrazoles | 2005 |
Design, synthesis, and evaluation of novelly substituted benzimidazole compounds as angiotensin II receptor antagonists.
Topics: Angiotensin Receptor Antagonists; Benzimidazoles; Drug Design; Models, Molecular; Protein Binding; Structure-Activity Relationship | 2005 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Angiotensin II--AT1 receptor antagonists: design, synthesis and evaluation of substituted carboxamido benzimidazole derivatives.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Drug Design; Hypertension; Rats; Receptor, Angiotensin, Type 1; Reference Standards | 2008 |
Design, synthesis, and evaluation of 5-sulfamoyl benzimidazole derivatives as novel angiotensin II receptor antagonists.
Topics: Angiotensin II Type 2 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Blood Pressure; Drug Design; Rats; Receptor, Angiotensin, Type 2 | 2008 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
CYP2C9-mediated metabolic activation of losartan detected by a highly sensitive cell-based screening assay.
Topics: Antihypertensive Agents; Aryl Hydrocarbon Hydroxylases; Benzbromarone; Biotransformation; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP2C9; Diclofenac; HEK293 Cells; Hep G2 Cells; Hepatocytes; Humans; Losartan; NF-E2-Related Factor 2; Semicarbazides; Sensitivity and Specificity; Time Factors; Uricosuric Agents | 2011 |
Evaluation of the relationship between sex, polymorphisms in CYP2C8 and CYP2C9, and pharmacokinetics of angiotensin receptor blockers.
Topics: Alleles; Angiotensin Receptor Antagonists; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2C9; Female; Half-Life; Humans; Male; Polymorphism, Genetic; Reference Values; Sex Factors | 2013 |
Structural determinants of subtype selectivity and functional activity of angiotensin II receptors.
Topics: Amino Acid Sequence; Angiotensin II Type 1 Receptor Blockers; Binding Sites; Ligands; Molecular Docking Simulation; Protein Binding; Protein Structure, Tertiary; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sequence Alignment | 2016 |
Mimicking of Arginine by Functionalized N(ω)-Carbamoylated Arginine As a New Broadly Applicable Approach to Labeled Bioactive Peptides: High Affinity Angiotensin, Neuropeptide Y, Neuropeptide FF, and Neurotensin Receptor Ligands As Examples.
Topics: Angiotensin II; Arginine; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Ligands; Molecular Structure; Neuropeptide Y; Neurotensin; Oligopeptides; Peptide Fragments; Receptors, Angiotensin; Receptors, Neuropeptide; Receptors, Neurotensin; Structure-Activity Relationship | 2016 |
Identification and development of non-cytotoxic cell death modulators: Impact of sartans and derivatives on PPARγ activation and on growth of imatinib-resistant chronic myelogenous leukemia cells.
Topics: Animals; Cell Death; Cell Proliferation; Chlorocebus aethiops; COS Cells; Drug Design; Drug Resistance, Neoplasm; Humans; Imatinib Mesylate; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; PPAR gamma; Structure-Activity Relationship; Telmisartan | 2020 |
Progress toward a Glycoprotein VI Modulator for the Treatment of Thrombosis.
Topics: Binding Sites; Biological Products; Humans; Ligands; Losartan; Molecular Dynamics Simulation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Protein Kinase Inhibitors; Signal Transduction; Small Molecule Libraries; Thrombosis | 2020 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Topical application of AT1 receptor antagonists prevents medial and neointimal proliferation after balloon injury.
Topics: Administration, Oral; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Arginine; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Bromodeoxyuridine; Carotid Artery Diseases; Carotid Artery, Common; Catheterization; Cell Division; Drug Synergism; Imidazoles; Losartan; Male; Muscle, Smooth, Vascular; Rats; Rats, Wistar; Tetrazoles; Tunica Intima; Tunica Media | 1994 |
Pharmacological profile of a highly potent and long-acting angiotensin II receptor antagonist, 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4- yl]methyl]-1H-benzimidazole-7-carboxylic acid (CV-11974), and its prodrug, (+/-)-1-(cyclohexyloxycarbonyloxy)-ethy
Topics: Adrenal Cortex; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cattle; Imidazoles; In Vitro Techniques; Iodine Radioisotopes; Kinetics; Losartan; Male; Muscle Contraction; Muscle, Smooth, Vascular; Prodrugs; Protein Binding; Rabbits; Rats; Rats, Sprague-Dawley; Substrate Specificity; Tetrazoles | 1993 |
A long-term receptor stimulation is requisite for angiotensin II-dependent DNA synthesis in vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Base Sequence; Benzimidazoles; Biphenyl Compounds; Calcium; Cells, Cultured; DNA Replication; Fibroblast Growth Factor 2; Imidazoles; In Vitro Techniques; Losartan; Molecular Sequence Data; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Pyridines; Rats; Rats, Inbred SHR; Receptors, Platelet-Derived Growth Factor; Tetrazoles | 1995 |
Lack of a centrally-mediated antihypertensive effect following acute or chronic central treatment with AT1-receptor antagonists in spontaneously hypertensive rats.
Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Brain; Hemodynamics; Imidazoles; Injections, Intraventricular; Losartan; Male; Rats; Rats, Inbred SHR; Tetrazoles | 1995 |
Angiotensin type 1 receptor antagonists CV-11974 and EXP 3174 cause selective renal vasodilatation in conscious spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Imidazoles; Losartan; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Circulation; Tetrazoles; Vasodilation | 1996 |
Candesartan (CV-11974) dissociates slowly from the angiotensin AT1 receptor.
Topics: Adrenal Cortex; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Cattle; Imidazoles; In Vitro Techniques; Losartan; Male; Rabbits; Receptors, Angiotensin; Tetrazoles; Vasoconstriction | 1997 |
Endothelin-1 is involved in stretch-induced early activation of B-type natriuretic peptide gene expression in atrial but not in ventricular myocytes: acute effects of mixed ET(A)/ET(B) and AT1 receptor antagonists in vivo and in vitro.
Topics: Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Bosentan; Endothelin Receptor Antagonists; Endothelin-1; Gene Expression Regulation; Losartan; Male; Myocardium; Natriuretic Peptide, Brain; Nerve Tissue Proteins; Perfusion; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; RNA, Messenger; Sulfonamides; Tetrazoles | 1997 |
Pharmacological profiles of a novel non-peptide angiotensin II type I receptor antagonist HR720 in vitro and in vivo.
Topics: Adrenal Glands; Adult; Aged; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cricetinae; Humans; Imidazoles; In Vitro Techniques; Losartan; Male; Mesocricetus; Middle Aged; Muscle, Smooth, Vascular; Rabbits; Rats; Tetrazoles; Thermodynamics | 1997 |
Responses to angiotensin peptides are mediated by AT1 receptors in the rat.
Topics: Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Female; Hindlimb; Imidazoles; Losartan; Male; Norepinephrine; Peptide Fragments; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles | 1998 |
Murine double nullizygotes of the angiotensin type 1A and 1B receptor genes duplicate severe abnormal phenotypes of angiotensinogen nullizygotes.
Topics: Adrenal Glands; Anesthetics; Angiotensin II; Angiotensinogen; Animals; Benzimidazoles; beta-Galactosidase; Biphenyl Compounds; Blood Pressure; Imidazoles; Infusions, Intravenous; Kidney; Losartan; Mice; Mice, Knockout; Myocardium; Phenotype; Pyridines; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Saralasin; Staining and Labeling; Tetrazoles; Thiopental; Zygote | 1998 |
Interactions between the renin-angiotensin system (RAS) and the sympathetic system.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Dose-Response Relationship, Drug; Imidazoles; Losartan; Male; Norepinephrine; Presynaptic Terminals; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Renin-Angiotensin System; Sympathetic Nervous System; Tetrazoles; Vasoconstrictor Agents | 1998 |
Effects of the angiotensin AT1 receptor blocker candesartan on myocardial ischemic/reperfusion injury.
Topics: Angiotensin Receptor Antagonists; Animals; Antioxidants; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Drug Therapy, Combination; Felodipine; Female; Hemodynamics; In Vitro Techniques; Indoles; Losartan; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Swine; Tetrazoles | 1999 |
AT1 receptor inhibition blunts angiotensin II-stimulated nitric oxide release in renal arteries.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Endothelium, Vascular; In Vitro Techniques; Losartan; Male; Microelectrodes; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renal Artery; Tetrazoles; Vasoconstriction | 1999 |
Binding of the antagonist [3H]candesartan to angiotensin II AT1 receptor-transfected [correction of tranfected] Chinese hamster ovary cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; CHO Cells; Computer Simulation; Cricetinae; Female; Humans; In Vitro Techniques; Inositol Phosphates; Ligands; Losartan; Protein Binding; Receptors, Angiotensin; Tetrazoles; Time Factors; Transfection | 1999 |
Effects of angiotensin II receptor blockade on proximal fluid uptake in the rat kidney.
Topics: Absorption; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Body Fluids; Dose-Response Relationship, Drug; Imidazoles; Kidney Tubules, Proximal; Losartan; Male; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles | 1999 |
Mechanistic differences of various AT1-receptor blockers in isolated vessels of different origin.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blood Proteins; Female; Humans; Imidazoles; In Vitro Techniques; Irbesartan; Kinetics; Losartan; Male; Muscle Contraction; Muscle, Smooth, Vascular; Portal Vein; Rabbits; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles | 1999 |
Insurmountable angiotensin AT1 receptor antagonists: the role of tight antagonist binding.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Binding, Competitive; Biphenyl Compounds; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Humans; Imidazoles; Irbesartan; Losartan; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Recombinant Proteins; Tetrazoles | 1999 |
Action of AT1 receptor antagonists on angiotensin II-induced tone in human isolated subcutaneous resistance arteries.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Arteries; Benzimidazoles; Biphenyl Compounds; Endothelium, Vascular; Humans; Imidazoles; Losartan; Muscle Tonus; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Vasoconstrictor Agents | 1999 |
Effects of the insurmountable angiotensin AT1 receptor antagonist candesartan and the surmountable antagonist losartan on ischemia/reperfusion injury in rat hearts.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Creatine Kinase; Dose-Response Relationship, Drug; Heart; Hemodynamics; In Vitro Techniques; Losartan; Male; Myocardial Reperfusion Injury; Norepinephrine; Perfusion; Pressure; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles; Time Factors; Vasoconstriction; Vasoconstrictor Agents | 1999 |
Efficacy of angiotensin II antagonists in hypertension.
Topics: Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Diuretics; Drug Interactions; Drug Therapy, Combination; Humans; Hypertension; Irbesartan; Losartan; Randomized Controlled Trials as Topic; Tetrazoles; Treatment Outcome; Valine; Valsartan | 1999 |
Blockade of the renin angiotensin system in heart failure: the potential place of angiotensin II receptor blockers.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Heart Failure; Humans; Losartan; Receptors, Angiotensin; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan | 2000 |
Effects of angiotensin II and antagonists on AT(1) receptor expression in mesangial cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Dexamethasone; Dose-Response Relationship, Drug; Gene Expression Regulation; Glomerular Mesangium; Imidazoles; Losartan; Male; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Tetrazoles | 1999 |
Comparative effects of angiotensin II AT-1-type receptor antagonists in vitro on human platelet activation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adult; Angiotensin II; Angiotensin Receptor Antagonists; Antibodies, Monoclonal; Benzimidazoles; Benzoates; Binding, Competitive; Biphenyl Compounds; Blood Platelets; Dose-Response Relationship, Drug; Humans; Imidazoles; Irbesartan; Losartan; Platelet Activation; Pyridines; Radioligand Assay; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Telmisartan; Tetrazoles; Thromboxane A2; Time Factors; Valine; Valsartan | 2000 |
In vitro inhibition screening of human hepatic P450 enzymes by five angiotensin-II receptor antagonists.
Topics: Acrylates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Imidazoles; In Vitro Techniques; Inhibitory Concentration 50; Irbesartan; Losartan; Microsomes, Liver; Protein Isoforms; Tetrazoles; Thiophenes; Valine; Valsartan | 2000 |
ACE inhibition and AT(1) receptor blockers: efficacy and duration in hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Blood Pressure Determination; Circadian Rhythm; Delayed-Action Preparations; Evidence-Based Medicine; Humans; Hypertension; Losartan; Patient Compliance; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles | 2000 |
Angiotensin II type 1 receptor antagonists. Why do some of them produce insurmountable inhibition?
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Binding Sites; Biphenyl Compounds; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Humans; Irbesartan; Losartan; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Recombinant Proteins; Tetrazoles | 2000 |
A two-state receptor model for the interaction between angiotensin II type 1 receptors and non-peptide antagonists.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; CHO Cells; Computer Simulation; Cricetinae; Dose-Response Relationship, Drug; Inositol Phosphates; Irbesartan; Kinetics; Losartan; Models, Biological; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles | 2001 |
Can angiotensin II receptor blockers be used in patients who have developed a cough or angioedema as a result of taking an ACE inhibitor?
Topics: Acrylates; Angioedema; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Black or African American; Clinical Trials as Topic; Cough; Female; Humans; Imidazoles; Irbesartan; Losartan; Male; Randomized Controlled Trials as Topic; Sex Factors; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan | 2001 |
Inhibition of platelet activation in stroke-prone spontaneously hypertensive rats: comparison of losartan, candesartan, and valsartan.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Platelets; Blood Pressure; Humans; Hypertension; Losartan; P-Selectin; Platelet Activation; Platelet Adhesiveness; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Stroke; Tetrazoles; Thromboxane A2; Valine; Valsartan | 2001 |
Sodium intake influences hemodynamic and neural responses to angiotensin receptor blockade in rostral ventrolateral medulla.
Topics: Angiotensin I; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Baroreflex; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Heart Failure; Heart Rate; Hemodynamics; Kidney; Losartan; Male; Medulla Oblongata; Microinjections; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Sodium, Dietary; Sympathetic Nervous System; Tetrazoles | 2001 |
Antihypertensive effects of losartan and candesartan.
Topics: Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Drug Therapy, Combination; Humans; Hypertension; Losartan; Tetrazoles | 2001 |
The influence of chronic antihypertensive treatment on the central pressor response in SHR.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Body Weight; Brain; Enalapril; Epinephrine; Heart Rate; Hydralazine; Hydrochlorothiazide; Hypertension; Injections, Intraventricular; Losartan; Male; Norepinephrine; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Saline Solution, Hypertonic; Tetrazoles | 2001 |
In vitro evidence for an intracellular site of angiotensin action.
Topics: Alternative Splicing; Angiotensin Receptor Antagonists; Angiotensinogen; Angiotensins; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Bromodeoxyuridine; Carcinoma, Hepatocellular; Cell Division; Clone Cells; Intracellular Fluid; Losartan; Mitotic Index; Mutagenesis, Site-Directed; Oligonucleotides, Antisense; Peptidyl-Dipeptidase A; Polymerase Chain Reaction; Rats; Receptors, Angiotensin; Receptors, Cytoplasmic and Nuclear; Recombinant Proteins; Renin; Sequence Deletion; Tetrazoles; Transfection; Tumor Cells, Cultured | 2001 |
Angiotensin receptor blocker losartan suppresses platelet activity by interfering with thromboxane signaling.
Topics: Angiotensin Receptor Antagonists; Animals; Arachidonic Acids; Benzimidazoles; Biphenyl Compounds; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Imidazoles; Losartan; Phospholipases A; Phospholipases A2; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Receptors, Thromboxane; Renin-Angiotensin System; Signal Transduction; Tetrazoles; Thromboxane A2 | 2001 |
Non-AT(1)-receptor-mediated protective effect of angiotensin against acute ischaemic stroke in the gerbil.
Topics: Acute Disease; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Brain Ischemia; Disease Models, Animal; Enalapril; Gerbillinae; Lisinopril; Losartan; Male; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Reproducibility of Results; Stroke; Tetrazoles | 2001 |
Angiotensin II directly stimulates ENaC activity in the cortical collecting duct via AT(1) receptors.
Topics: Amiloride; Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Benzofurans; Biphenyl Compounds; Hydrogen-Ion Concentration; Intracellular Membranes; Ionophores; Kidney Tubules, Collecting; Losartan; Mice; Microscopy, Fluorescence; Monensin; Rabbits; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Signal Transduction; Sodium Chloride; Tetrazoles | 2002 |
Losartan inhibits in vitro platelet activation: comparison with candesartan and valsartan.
Topics: Adenosine Diphosphate; Adult; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Blood Platelets; Cells, Cultured; Drug Interactions; Humans; Losartan; Male; Platelet Activation; Platelet Aggregation Inhibitors; Receptor, Angiotensin, Type 1; Tetrazoles; Thromboxane A2; Valine; Valsartan | 2000 |
Effect of dietary sodium intake on central angiotensinergic pathways.
Topics: Angiotensin Receptor Antagonists; Angiotensins; Animals; Antihypertensive Agents; Benzimidazoles; Bicuculline; Biphenyl Compounds; Blood Pressure; Brain; Diet, Sodium-Restricted; Kidney; Losartan; Medulla Oblongata; Microinjections; Paraventricular Hypothalamic Nucleus; Rats; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Sympathetic Nervous System; Tetrazoles | 2002 |
Comparison of the antagonistic effects of different angiotensin II receptor blockers in human coronary arteries.
Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Base Sequence; Benzimidazoles; Biphenyl Compounds; Coronary Vessels; Culture Techniques; Dose-Response Relationship, Drug; Female; Humans; Imidazoles; Losartan; Male; Middle Aged; Molecular Sequence Data; Probability; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazoles; Valine; Valsartan; Vasoconstriction | 2002 |
Control of dendritic cell differentiation by angiotensin II.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antibodies; Benzimidazoles; Biphenyl Compounds; Cell Differentiation; Cells, Cultured; Dendritic Cells; Endocytosis; Hematopoietic Stem Cells; Humans; Irbesartan; Losartan; Lymphocyte Activation; Mice; Models, Biological; Monocytes; Phenotype; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles | 2003 |
Effects of angiotensin II receptor antagonists on [(123)I]metaiodobenzylguanidine myocardial imaging findings and neurohumoral factors in chronic heart failure.
Topics: 3-Iodobenzylguanidine; Aged; Aged, 80 and over; Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atrial Natriuretic Factor; Benzimidazoles; Biomarkers; Biphenyl Compounds; Blood Pressure; Creatinine; Echocardiography; Female; Heart; Heart Failure; Humans; Losartan; Male; Middle Aged; Natriuretic Peptide, Brain; Neurotransmitter Agents; Norepinephrine; Potassium; Radionuclide Imaging; Radiopharmaceuticals; Receptors, Angiotensin; Renin; Severity of Illness Index; Statistics as Topic; Stroke Volume; Tetrazoles; Time Factors; Treatment Outcome; Ventricular Dysfunction, Left | 2002 |
Binding of KRH-594, an antagonist of the angiotensin II type 1 receptor, to cloned human and rat angiotensin II receptors.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Chlorocebus aethiops; COS Cells; Dose-Response Relationship, Drug; Humans; Imidazoles; In Vitro Techniques; Liver; Losartan; Membranes; Oligopeptides; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Thiadiazoles; Time Factors; Transfection | 2002 |
Functional antagonism of different angiotensin II type I receptor blockers in human arteries.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Dose-Response Relationship, Drug; Humans; Imidazoles; In Vitro Techniques; Losartan; Mammary Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Receptor, Angiotensin, Type 1; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents | 2002 |
AT1 receptors in the RVLM mediate pressor responses to emotional stress in rabbits.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Baroreflex; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Consciousness; Female; Glutamates; Heart Rate; Hypertension; Kidney; Losartan; Male; Medulla Oblongata; Rabbits; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Stress, Psychological; Sympathetic Nervous System; Tetrazoles | 2003 |
Peptide and nonpeptide antagonist interaction with constitutively active human AT1 receptors.
Topics: Alanine; Amino Acid Substitution; Animals; Antihypertensive Agents; Aspartic Acid; Benzimidazoles; Biphenyl Compounds; CHO Cells; Cricetinae; Humans; Imidazoles; Kinetics; Losartan; Mutagenesis, Site-Directed; Radioligand Assay; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Tetrazoles; Transfection; Tritium | 2003 |
Cardiology patient page. Angiotensin receptor blockers.
Topics: Acrylates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Diuretics; Dizziness; Drug Combinations; Drug Interactions; Heart Failure; Humans; Hypertension; Imidazoles; Irbesartan; Kidney Diseases; Losartan; Olmesartan Medoxomil; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan | 2003 |
[Fast-acting sartan. High blood pressure therapy without long waiting time].
Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Olmesartan Medoxomil; Rats; Tetrazoles; Time Factors; Valine; Valsartan | 2003 |
Myogenic constriction is increased in mesenteric resistance arteries from rats with chronic heart failure: instantaneous counteraction by acute AT1 receptor blockade.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Bridged Bicyclo Compounds, Heterocyclic; Captopril; Chronic Disease; Coronary Vessels; Disease Models, Animal; Endothelium-Dependent Relaxing Factors; Endothelium, Vascular; Fatty Acids, Unsaturated; Heart; Heart Failure; Hydrazines; Imidazoles; Indomethacin; Lisinopril; Losartan; Male; Mesenteric Arteries; Nitric Oxide; omega-N-Methylarginine; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Superoxide Dismutase; Sympathetic Nervous System; Tetrazoles; Tetrodotoxin; Vascular Resistance | 2003 |
Choice of treatment: outcomes and treatment goals.
Topics: Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Clinical Trials as Topic; Drug Approval; Losartan; Tetrazoles; United States; United States Food and Drug Administration | 2003 |
Of millimeterology and cannibalism: comparative antihypertensive efficacy of angiotensin receptor blockers.
Topics: Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Clinical Trials as Topic; Drug Approval; Drug Industry; Humans; Losartan; Tetrazoles; United States; United States Food and Drug Administration | 2003 |
[Dosage equivalents of AT1-receptor antagonists available in Germany].
Topics: Acrylates; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Clinical Trials as Topic; Germany; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Olmesartan Medoxomil; Placebos; Telmisartan; Tetrazoles; Therapeutic Equivalency; Thiophenes; Time Factors; Valine; Valsartan | 2003 |
"Network leaning" as a mechanism of insurmountable antagonism of the angiotensin II type 1 receptor by non-peptide antagonists.
Topics: Amino Acid Sequence; Animals; Benzimidazoles; Binding, Competitive; Biphenyl Compounds; Cell Membrane; COS Cells; Dose-Response Relationship, Drug; Imidazoles; Kinetics; Ligands; Losartan; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Peptides; Protein Conformation; Rats; Receptor, Angiotensin, Type 1; Temperature; Tetrazoles; Time Factors | 2004 |
Cerebral ischemia enhances vascular angiotensin AT1 receptor-mediated contraction in rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Brain Ischemia; Culture Techniques; Infarction, Middle Cerebral Artery; Losartan; Male; Middle Cerebral Artery; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; RNA, Messenger; Tetrazoles; Vasoconstriction; Vasoconstrictor Agents | 2004 |
[AT-1 blockers are different in their effects. The forgetful patients begin to notice it especially].
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Diuretics; Double-Blind Method; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Losartan; Meta-Analysis as Topic; Placebos; Randomized Controlled Trials as Topic; Sodium Chloride Symporter Inhibitors; Stroke; Tetrazoles; Time Factors; Valine; Valsartan | 2003 |
Flow-dependent dilation mediated by endogenous kinins requires angiotensin AT2 receptors.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Bradykinin; Bradykinin B2 Receptor Antagonists; Carotid Arteries; Hemorheology; Imidazoles; Losartan; Male; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Mice, Knockout; Phenylephrine; Pyridines; Receptor, Angiotensin, Type 2; Receptor, Bradykinin B2; Tetrazoles; Tissue Kallikreins; Vasodilation; Vasodilator Agents | 2004 |
Pharmacological properties of angiotensin II receptors in cultured rabbit gingival fibroblasts.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Binding, Competitive; Biphenyl Compounds; Blotting, Western; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Fibroblasts; Gingiva; Kinetics; Losartan; Rabbits; Radioligand Assay; Receptors, Angiotensin; Saralasin; Tetrazoles; Tritium | 2004 |
Valsartan treatment of hypertension--does VALUE add value?
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Endpoint Determination; Humans; Hypertension; Losartan; Randomized Controlled Trials as Topic; Risk Factors; Tetrazoles; Valine; Valsartan | 2004 |
Reduction of vascular noradrenaline sensitivity by AT1 antagonists depends on functional sympathetic innervation.
Topics: Adrenergic alpha-Antagonists; Angiotensin II Type 1 Receptor Blockers; Animals; Atropine; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Desipramine; Diastole; Dose-Response Relationship, Drug; Losartan; Male; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Reserpine; Sympathectomy, Chemical; Sympathetic Nervous System; Symporters; Tetrazoles; Tubocurarine; Yohimbine | 2004 |
Transforming growth factor beta receptor endoglin is expressed in cardiac fibroblasts and modulates profibrogenic actions of angiotensin II.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Antibodies, Monoclonal; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Collagen Type I; Endoglin; Fibroblasts; Flavonoids; Gene Expression Regulation; Imidazoles; Intracellular Signaling Peptides and Proteins; Losartan; MAP Kinase Signaling System; Matrix Metalloproteinase 1; Myocardium; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Transforming Growth Factor beta; RNA, Messenger; Signal Transduction; Tetrazoles; Valine; Valsartan | 2004 |
Antiproteinuric effect of ARB in lupus nephritis patients with persistent proteinuria despite immunosuppressive therapy.
Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cholesterol; Complement System Proteins; Female; Humans; Immunosuppressive Agents; Losartan; Lupus Nephritis; Male; Middle Aged; Proteinuria; Retrospective Studies; Tetrazoles | 2005 |
ATR blockade reduces IFN-gamma production in lymphocytes in vivo and in vitro.
Topics: Adult; Aged; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Female; Humans; Interferon-gamma; Losartan; Lymphocyte Activation; Lymphocytes; Male; Middle Aged; Polymerase Chain Reaction; RNA, Messenger; Tetrazoles | 2005 |
Researched Medicines Industry (RMI) Code of Practice complaints 2004.
Topics: Advertising; Benzimidazoles; Biphenyl Compounds; Carbazoles; Carvedilol; Codes of Ethics; Dissent and Disputes; Drug Industry; Humans; Losartan; New Zealand; Propanolamines; Tetrazoles | 2005 |
Efficacy and duration of action of the four selective angiotensin II subtype 1 receptor blockers, losartan, candesartan, valsartan and telmisartan, in patients with essential hypertension determined by home blood pressure measurements.
Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure Monitoring, Ambulatory; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Telmisartan; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2005 |
Peripheral sympatholytic actions of four AT1 antagonists: are they relevant for long-term antihypertensive efficacy?
Topics: Acrylates; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Electric Stimulation; Imidazoles; Irbesartan; Losartan; Male; Norepinephrine; Rats; Rats, Inbred SHR; Sympathetic Fibers, Postganglionic; Sympatholytics; Tetrazoles; Thiophenes; Time Factors; Treatment Outcome | 2005 |
Evaluation of intrarenal hemodynamics by Doppler ultrasonography for renoprotective effect of angiotensin receptor blockade.
Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Female; Hemodynamics; Humans; Hypertension; Kidney; Kidney Diseases; Losartan; Male; Middle Aged; Tetrazoles; Ultrasonography, Doppler; Valine; Valsartan | 2005 |
[Beneficial effects of combination therapy with losartan and low-dose hydrochlorothiazide in the treatment of essential hypertension].
Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Diuretics; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Tetrazoles | 2005 |
[Angiotensin II AT1 receptor antagonists as antiinflammatory and gastric protection drugs].
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Inflammatory Agents; Benzimidazoles; Biphenyl Compounds; Carrageenan; Disease Models, Animal; Edema; Female; Gastric Mucosa; Indomethacin; Losartan; Rats; Rats, Wistar; Stomach Ulcer; Tetrazoles; Valine; Valsartan | 2006 |
Hypertension, diuretics, and uric acid.
Topics: Antihypertensive Agents; Antioxidants; Benzimidazoles; Biphenyl Compounds; Cardiovascular System; Diuretics; Humans; Hypertension; Losartan; Reactive Oxygen Species; Tetrazoles; Uric Acid | 2006 |
Inhibitory effects of angiotensin II receptor antagonists and leukotriene receptor antagonists on the transport of human organic anion transporter 4.
Topics: Acetates; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biological Transport; Biphenyl Compounds; Blotting, Western; Cell Line; Chromones; Cyclopropanes; Dose-Response Relationship, Drug; Estrone; Humans; Imidazoles; Indoles; Leukotriene Antagonists; Losartan; Molecular Structure; Organic Anion Transporters, Sodium-Independent; Phenylcarbamates; Quinolines; Structure-Activity Relationship; Sulfides; Sulfonamides; Tetrazoles; Tosyl Compounds; Transfection; Tritium; Valine; Valsartan | 2006 |
Evaluation of the cost savings and clinical outcomes of switching patients from atorvastatin to simvastatin and losartan to candesartan in a Primary Care setting.
Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Antihypertensive Agents; Atorvastatin; Benzimidazoles; Biphenyl Compounds; Cost Savings; Cost-Benefit Analysis; Drug Costs; Drugs, Generic; Family Practice; Female; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertension; Losartan; Male; Middle Aged; Patient Satisfaction; Pyrroles; Simvastatin; Tetrazoles; Treatment Outcome | 2007 |
Angiotensin blockade as sole treatment for proteinuric kidney disease in children.
Topics: Adolescent; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Child; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enalapril; Female; Glomerular Filtration Rate; Humans; Kidney Diseases; Losartan; Male; Proteinuria; Retrospective Studies; Tetrazoles | 2007 |
Angiotensin-converting enzyme inhibitor enhances liver regeneration following partial hepatectomy: involvement of bradykinin B2 and angiotensin AT1 receptors.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Bradykinin; Bradykinin B2 Receptor Antagonists; Bromodeoxyuridine; Dose-Response Relationship, Drug; Hepatectomy; Hepatocyte Growth Factor; Hepatocytes; Lisinopril; Liver Regeneration; Losartan; Male; Rats; Rats, Sprague-Dawley; Receptor, Bradykinin B2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazoles; Time Factors | 2007 |
Angiotensin II receptor blockers for the treatment of heart failure: a class effect?
Topics: Age Factors; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; British Columbia; Drug Prescriptions; Female; Heart Failure; Hospital Information Systems; Humans; Irbesartan; Losartan; Male; Ontario; Proportional Hazards Models; Quebec; Retrospective Studies; Survival Analysis; Survival Rate; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2007 |
Angiotensin AT1 receptor blockers suppress ischemia/reperfusion-induced gastric injury in rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Capillary Permeability; Gastric Mucosa; Hydrogen Peroxide; Losartan; Male; Microcirculation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tetrazoles; Valine; Valsartan | 2007 |
Switch strategies in the management of hypertension: a cost minimisation analysis of angiotensin receptor blocker based regimen.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cost-Benefit Analysis; Drug Costs; Humans; Hypertension; Irbesartan; Losartan; Markov Chains; Tetrazoles; Valine; Valsartan | 2008 |
Evaluation of the clinical outcomes of switching patients from atorvastatin to simvastatin and losartan to candesartan in a primary care setting: 2 years on.
Topics: Aged; Aged, 80 and over; Anticholesteremic Agents; Antihypertensive Agents; Atorvastatin; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cholesterol; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Hypertension; Losartan; Male; Pyrroles; Retrospective Studies; Simvastatin; Tetrazoles; Therapeutic Equivalency; Treatment Outcome | 2008 |
Enzyme-assisted synthesis and structure characterization of glucuronic acid conjugates of losartan, candesartan, and zolarsartan.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Cattle; Deer; Glucuronic Acid; Glucuronides; Glucuronosyltransferase; Humans; Losartan; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microsomes, Liver; Rats; Swine; Tetrazoles | 2008 |
Identifying patterns of adverse event reporting for four members of the angiotensin II receptor blockers class of drugs: revisiting the Weber effect.
Topics: Adverse Drug Reaction Reporting Systems; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Drug Approval; Humans; Irbesartan; Losartan; Tetrazoles; Time Factors; United States; Valine; Valsartan | 2008 |
Uricosuric action of losartan via the inhibition of urate transporter 1 (URAT 1) in hypertensive patients.
Topics: Administration, Oral; Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Blood Pressure; DNA; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Hypertension; Hyperuricemia; Losartan; Male; Mutation; Organic Anion Transporters; Organic Cation Transport Proteins; Polymerase Chain Reaction; Tetrazoles; Treatment Outcome; Uric Acid | 2008 |
The human UDP-glucuronosyltransferase UGT1A3 is highly selective towards N2 in the tetrazole ring of losartan, candesartan, and zolarsartan.
Topics: Animals; Benzimidazoles; Biphenyl Compounds; Cattle; Deer; Glucuronides; Glucuronosyltransferase; Humans; Losartan; Male; Microsomes, Liver; Rabbits; Rats; Rats, Sprague-Dawley; Species Specificity; Substrate Specificity; Swine; Tetrazoles | 2008 |
Telmisartan and carotid intima-media thickness regression: a class effect of angiotensin-receptor blockers?
Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Biphenyl Compounds; Carotid Arteries; Humans; Irbesartan; Losartan; Telmisartan; Tetrazoles; Tunica Intima; Tunica Media; Valine; Valsartan | 2008 |
Angiotensin blockade prevents salt-induced injury of the renal circulation in spontaneously hypertensive rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Benzimidazoles; Biphenyl Compounds; Body Weight; Heart Ventricles; Hemodynamics; Hypertension; Kidney; Losartan; Male; Organ Size; Rats; Rats, Inbred SHR; Renal Circulation; Renal Insufficiency; Sodium Chloride, Dietary; Tetrazoles | 2009 |
Binding sites of valsartan, candesartan and losartan with angiotensin II receptor 1 subtype by molecular modeling.
Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Binding Sites; Biphenyl Compounds; Cell Line; Humans; Losartan; Models, Molecular; Protein Conformation; Radioligand Assay; Receptor, Angiotensin, Type 1; Tetrazoles; Valine; Valsartan | 2009 |
Angiotensin II receptors are expressed and functional in human esophageal mucosa.
Topics: Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Benzimidazoles; Biopsy; Biphenyl Compounds; Blood Vessels; Electric Impedance; Electrophysiological Phenomena; Epithelial Cells; Esophagus; Female; Gene Expression; Humans; Hydrochloric Acid; Imidazoles; Losartan; Male; Middle Aged; Mucous Membrane; Peptidyl-Dipeptidase A; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles | 2009 |
Effects of losartan vs candesartan in reducing cardiovascular events in the primary treatment of hypertension.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Female; Humans; Hypertension; Incidence; Kaplan-Meier Estimate; Losartan; Male; Middle Aged; Myocardial Infarction; Myocardial Ischemia; Primary Health Care; Proportional Hazards Models; Registries; Risk Factors; Risk Reduction Behavior; Sensitivity and Specificity; Stroke; Sweden; Tetrazoles | 2010 |
Interaction of angiotensin II type 1 receptor blockers with P-gp substrates in Caco-2 cells and hMDR1-expressing membranes.
Topics: Adenosine Triphosphatases; Angiotensin II Type 1 Receptor Blockers; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; Benzoates; Biological Transport; Biphenyl Compounds; Caco-2 Cells; Calcium Channel Blockers; Cardiotonic Agents; Cell Membrane; Digoxin; Drug Interactions; Humans; Irbesartan; Losartan; Telmisartan; Tetrazoles; Verapamil | 2010 |
HEAAL: the final chapter in the story of angiotensin receptor blockers in heart failure--lessons learnt from a decade of trials.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Evidence-Based Medicine; Heart Failure; Humans; Losartan; Tetrazoles; Time Factors; Valine; Valsartan | 2010 |
Internalization of constitutively active N111G MUTANT of AT1 receptor induced by angiotensin II-receptor antagonists candesartan, losartan, and telmisartan: comparison with valsartan.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Biphenyl Compounds; Chlorocebus aethiops; COS Cells; Losartan; Mutagenesis, Site-Directed; Mutation; Receptor, Angiotensin, Type 1; Telmisartan; Tetrazoles; Valine; Valsartan | 2010 |
Health-care costs of losartan and candesartan in the primary treatment of hypertension.
Topics: Acute Coronary Syndrome; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Brain Ischemia; Drug Costs; Health Care Costs; Hospitalization; Humans; Hypertension; Long-Term Care; Losartan; Registries; Sweden; Tetrazoles | 2011 |
A single-nucleotide polymorphism of alanine to threonine at position 163 of the human angiotensin II type 1 receptor impairs Losartan affinity.
Topics: Alanine; Angiotensin II; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Chlorocebus aethiops; COS Cells; Humans; Imidazoles; Inositol Phosphates; Irbesartan; Losartan; Polymorphism, Single Nucleotide; Receptor, Angiotensin, Type 1; Telmisartan; Tetrazoles; Threonine; Valine; Valsartan | 2010 |
Renin-Angiotensin system blockade for diabetic nephropathy prevention.
Topics: Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Enalapril; Female; Humans; Losartan; Male; Prognosis; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Risk Assessment; Tetrazoles; Treatment Outcome | 2010 |
Comparison of angiotensin II type 1-receptor blockers to regress pressure overload-induced cardiac hypertrophy in mice.
Topics: Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Thoracic; Atrial Natriuretic Factor; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Cardiomegaly; Echocardiography; Gene Expression; Hemodynamics; Imidazoles; Losartan; Male; Mice; Myocardium; Reverse Transcriptase Polymerase Chain Reaction; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2010 |
The angiotensin II type 1 receptor antagonist Losartan binds and activates bradykinin B2 receptor signaling.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensins; Animals; Benzimidazoles; Binding, Competitive; Biphenyl Compounds; Bradykinin; Bradykinin B2 Receptor Antagonists; Chlorocebus aethiops; COS Cells; Hydrolysis; Kallikrein-Kinin System; Losartan; Myocardial Contraction; Phosphatidylinositols; Rats; Receptor, Angiotensin, Type 1; Receptor, Bradykinin B2; Renin-Angiotensin System; Signal Transduction; Tetrazoles | 2011 |
Association of candesartan vs losartan with all-cause mortality in patients with heart failure.
Topics: Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Cause of Death; Female; Heart Failure; Humans; Losartan; Male; Middle Aged; Registries; Risk; Survival Analysis; Sweden; Tetrazoles; Ventricular Dysfunction, Left | 2011 |
Easy money? Health cost savings resulting from the switch from a branded drug to a low-cost generic drug in the same class.
Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Female; Heart Failure; Humans; Hypertension; Losartan; Male; Tetrazoles | 2011 |
Waste not, want not: free money, moral hazard and value-based prescribing.
Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Female; Heart Failure; Humans; Hypertension; Losartan; Male; Tetrazoles | 2011 |
Cardiovascular events in subgroups of patients during primary treatment of hypertension with candesartan or losartan.
Topics: Aged; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cardiovascular Diseases; Cardiovascular System; Confidence Intervals; Female; Humans; Hypertension; Kaplan-Meier Estimate; Losartan; Male; Middle Aged; Odds Ratio; Propensity Score; Risk Assessment; Risk Factors; Risk Reduction Behavior; Sweden; Tetrazoles | 2011 |
Use of enterally delivered angiotensin II type Ia receptor antagonists to reduce the severity of colitis.
Topics: Administration, Oral; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Colitis; Colon; Cytokines; Dextran Sulfate; Feces; Gene Expression Regulation; Losartan; Male; Mice; Molecular Structure; Specific Pathogen-Free Organisms; Tetrazoles | 2011 |
[Remarkable results with candesartan].
Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Dose-Response Relationship, Drug; Evidence-Based Medicine; Follow-Up Studies; Heart Failure; Humans; Losartan; Randomized Controlled Trials as Topic; Tetrazoles; Treatment Outcome | 2011 |
Candesartan vs losartan and mortality in patients with heart failure.
Topics: Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Europe; Guideline Adherence; Heart Failure; Humans; Losartan; Registries; Sweden; Tetrazoles; Ventricular Dysfunction, Left | 2011 |
Candesartan vs losartan and mortality in patients with heart failure.
Topics: Benzimidazoles; Biphenyl Compounds; Dose-Response Relationship, Drug; Heart Failure; Humans; Losartan; Registries; Reproducibility of Results; Sweden; Tetrazoles | 2011 |
Comparative biophysical studies of sartan class drug molecules losartan and candesartan (CV-11974) with membrane bilayers.
Topics: Benzimidazoles; Biphenyl Compounds; Calorimetry, Differential Scanning; Lipid Bilayers; Losartan; Magnetic Resonance Spectroscopy; Receptor, Angiotensin, Type 1; Solvents; Spectrum Analysis, Raman; Tetrazoles | 2011 |
Comparative effectiveness of individual angiotensin receptor blockers on risk of mortality in patients with chronic heart failure.
Topics: Aged; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Chronic Disease; Confounding Factors, Epidemiologic; Electronic Health Records; Female; Heart Failure; Hospitalization; Humans; Irbesartan; Losartan; Male; Models, Structural; Proportional Hazards Models; Retrospective Studies; Risk; Tetrazoles; Treatment Outcome; United States; Valine; Valsartan | 2012 |
Angiotensin AT1 receptor blockers suppress oxidized low-density lipoprotein-derived formation of foam cells.
Topics: Acetyl-CoA C-Acetyltransferase; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Cholesterol Esters; Enzyme Inhibitors; ErbB Receptors; Foam Cells; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Lipoproteins, LDL; Losartan; Macrophages; Quinazolines; Tetrazoles; Triglycerides; Tyrphostins | 2012 |
Association of treatment with losartan vs candesartan and mortality among patients with heart failure.
Topics: Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Cohort Studies; Denmark; Dose-Response Relationship, Drug; Female; Heart Failure; Humans; Losartan; Male; Registries; Risk; Tetrazoles | 2012 |
Subtle issues in model specification and estimation of marginal structural models.
Topics: Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Female; Heart Failure; Humans; Irbesartan; Losartan; Male; Tetrazoles; Valine; Valsartan | 2012 |
Modulation of transforming growth factor-β signaling and extracellular matrix production in myxomatous mitral valves by angiotensin II receptor blockers.
Topics: Angiotensin Receptor Antagonists; Benzimidazoles; Benzoates; Biphenyl Compounds; Cells, Cultured; Collagen; Elastic Tissue; Extracellular Matrix Proteins; Fibrosis; Gene Expression Regulation; Genetic Diseases, X-Linked; Heart Defects, Congenital; Humans; Losartan; Mitral Valve Insufficiency; Mitral Valve Prolapse; Myxoma; Polymerase Chain Reaction; Signal Transduction; Smad2 Protein; Smad3 Protein; Telmisartan; Tetrazoles; Transforming Growth Factor beta; Vimentin | 2012 |
Modulation of haemodynamics, endogeneous antioxidant enzymes, and pathophysiological changes by selective inhibition of angiotensin II type 1 receptors in pressureoverload rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cardiomegaly; Catalase; Disease Models, Animal; Hypertension; Irbesartan; Losartan; Male; Myocardium; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Superoxide Dismutase; Tetrazoles; Time Factors | 2013 |
Comparative effectiveness of angiotensin-receptor blockers for preventing macrovascular disease in patients with diabetes: a population-based cohort study.
Topics: Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Benzimidazoles; Benzoates; Biphenyl Compounds; Diabetic Angiopathies; Dose-Response Relationship, Drug; Female; Heart Failure; Humans; Irbesartan; Losartan; Male; Myocardial Infarction; Proportional Hazards Models; Retrospective Studies; Stroke; Telmisartan; Tetrazoles; Treatment Outcome | 2013 |
Examining the association of olmesartan and other angiotensin receptor blockers with overall and cause-specific mortality.
Topics: Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Cardiovascular Diseases; Cohort Studies; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Male; Middle Aged; Proportional Hazards Models; Registries; Retrospective Studies; Survival Rate; Taiwan; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2014 |
Angiotensin II type 1 receptor blockade suppresses light-induced neural damage in the mouse retina.
Topics: Acetylcysteine; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Apoptosis; Benzimidazoles; Biphenyl Compounds; Dose-Response Relationship, Drug; Fas Ligand Protein; Gene Expression Regulation; Light; Losartan; Male; Mice; Mice, Inbred BALB C; Proto-Oncogene Proteins c-fos; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Retinal Degeneration; Retinal Photoreceptor Cell Outer Segment; Signal Transduction; Tetrazoles; Valine; Valsartan | 2014 |
Differential effects of angiotensin II receptor blockers on Aβ generation.
Topics: Amyloid beta-Peptides; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Biphenyl Compounds; Cells, Cultured; Fibroblasts; Imidazoles; Losartan; Mice, Inbred C57BL; Mice, Knockout; Peptide Fragments; Phosphatidylinositol 3-Kinases; Receptor, Angiotensin, Type 1; Signal Transduction; Telmisartan; Tetrazoles; Valine; Valsartan | 2014 |
Effect of dietary fiber on the level of free angiotensin II receptor blocker in vitro.
Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Biphenyl Compounds; Dietary Fiber; Electrolytes; Hydrogen-Ion Concentration; Losartan; Sodium Chloride; Telmisartan; Tetrazoles | 2014 |
Dosage of angiotensin-II receptor blockers in heart failure patients following changes in Danish drug reimbursement policies.
Topics: Aged; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Denmark; Female; Heart Failure; Humans; Insurance, Health, Reimbursement; Losartan; Male; Tetrazoles; Valine; Valsartan | 2014 |
Synthesis and evaluation of the novel 2-[¹⁸F]fluoro-3-propoxy-triazole-pyridine-substituted losartan for imaging AT₁ receptors.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Fluorine Radioisotopes; Kidney; Losartan; Male; Positron-Emission Tomography; Pyridines; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Tetrazoles | 2014 |
Brain Angiotensin II AT1 receptors are involved in the acute and long-term amphetamine-induced neurocognitive alterations.
Topics: Amphetamines; Angiotensin II Type 1 Receptor Blockers; Animals; Avoidance Learning; Behavior, Animal; Benzimidazoles; Biphenyl Compounds; Central Nervous System Stimulants; Cognition Disorders; Hippocampus; Injections, Intraventricular; Losartan; Male; Memory, Long-Term; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Synaptic Transmission; Tetrazoles | 2016 |
The velocity of antihypertensive effects of seven angiotensin II receptor blockers determined by home blood pressure measurements.
Topics: Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Blood Pressure Determination; Female; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Male; Middle Aged; Oxadiazoles; Self Care; Telmisartan; Tetrazoles; Time Factors; Valsartan | 2016 |
Mechanical activation of angiotensin II type 1 receptors causes actin remodelling and myogenic responsiveness in skeletal muscle arterioles.
Topics: Abdominal Muscles; Actins; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Arterioles; Benzimidazoles; Biphenyl Compounds; Captopril; Cells, Cultured; Diglycerides; Imidazoles; Indoles; Losartan; Male; Maleimides; Muscle Development; Muscle Fibers, Skeletal; Pressure; Protein Kinase C; Pyridines; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Tetrazoles; Vasoconstriction; Vasoconstrictor Agents | 2016 |
Neuroprotective effects of AT1 receptor antagonists after experimental ischemic stroke: what is important?
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blood-Brain Barrier; Brain Ischemia; Disease Models, Animal; Dose-Response Relationship, Drug; Irbesartan; Losartan; Male; Neuroprotective Agents; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Stroke; Tetrazoles; Tissue Distribution | 2017 |
Candesartan, rather than losartan, improves motor dysfunction in thioacetamide-induced chronic liver failure in rats.
Topics: Alanine Transaminase; Ammonia; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Disease Models, Animal; End Stage Liver Disease; Enzyme-Linked Immunosorbent Assay; gamma-Glutamyltransferase; Glutathione; Liver; Liver Cirrhosis; Locomotion; Losartan; Male; Malondialdehyde; Motor Disorders; Random Allocation; Rats, Sprague-Dawley; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; Tetrazoles; Thioacetamide; Treatment Outcome; Tumor Necrosis Factor-alpha | 2017 |
Impact of the Commercialization of Three Generic Angiotensin II Receptor Blockers on Adverse Events in Quebec, Canada: A Population-Based Time Series Analysis.
Topics: Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Databases, Factual; Drug Costs; Drug Substitution; Drugs, Generic; Emergency Service, Hospital; Humans; Hypertension; Losartan; Patient Admission; Patient Safety; Population Surveillance; Quebec; Referral and Consultation; Retrospective Studies; Risk Factors; Tetrazoles; Therapeutic Equivalency; Time Factors; Treatment Outcome; Valsartan | 2017 |
Angiotensin receptor blocker use and gastro-oesophageal cancer survival: a population-based cohort study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Child; Child, Preschool; Cohort Studies; Diabetic Neuropathies; Esophageal Neoplasms; Female; Heart Failure; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Imidazoles; Infant; Infant, Newborn; Losartan; Male; Middle Aged; Registries; Stomach Neoplasms; Survival Analysis; Tetrazoles; Young Adult | 2018 |
Angiotensin II type 1 receptor blockers decrease kynurenic acid production in rat kidney in vitro.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Humans; Imidazoles; Irbesartan; Kidney; Kynurenic Acid; Losartan; Male; Rats, Wistar; Telmisartan; Tetrazoles; Transaminases; Valsartan | 2019 |
Investigation of Carcinogenic Impurities of N-Nitrosamines in Sartan Pharmaceutical Products Marketed in Brazil: Development and Validation of Method Based on High-Performance Liquid Chromatography-Tandem Mass Spectrometry.
Topics: Angiotensin II Type 1 Receptor Blockers; Brazil; Carcinogens; Chromatography, High Pressure Liquid; Humans; Irbesartan; Losartan; Nitrosamines; Pharmaceutical Preparations; Tandem Mass Spectrometry; Telmisartan; Valsartan | 2023 |
A collaborative study of the impact of N-nitrosamines presence and ARB recall on ARB utilization - results from IQVIA™ Disease Analyzer Germany.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Germany; Humans; Hypertension; Irbesartan; Losartan; Nitrosamines; Valsartan | 2023 |