candesartan and indomethacin

candesartan has been researched along with indomethacin in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (16.67)18.2507
2000's9 (50.00)29.6817
2010's5 (27.78)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Iida, K; Itoh, S; Kohama, Y; Kuroda, T; Mimura, T1
Behrends, M; Dörge, H; Heusch, G; Jalowy, A; Schulz, R1
Akashi, K; Asayama, J; Kawahara, A; Keira, N; Kobara, M; Matoba, S; Nakagawa, M; Tatsumi, T1
Abe, I; Fujii, K; Goto, K; Kansui, Y1
Buikema, H; de Zeeuw, D; Gschwend, S; Henning, RH; Pinto, YM; van Gilst, WH1
Bivol, LM; Iversen, BM; Vågnes, OB1
Elling, CE; Frimurer, TM; Gerlach, LO; Högberg, T; Kostenis, E; Ulven, T1
Edvinsson, L; Malmsjö, M; Nilsson, E; Vikman, P; Wackenfors, A1
Cesolari, JA; Laudanno, OM1
Castrop, H; Hansen, PB; Oppermann, M; Schnermann, J1
Handa, O; Ichikawa, H; Kokura, S; Naito, Y; Okuda, T; Takagi, T; Yoshida, N; Yoshikawa, T1
Amin, E; Ashour, O; Morsy, M; Rofaeil, R1
Awad, AS; El Morsy, EM; Kamel, R1

Reviews

1 review(s) available for candesartan and indomethacin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

17 other study(ies) available for candesartan and indomethacin

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Inhibitory effect of tuna peptide on endothelin production in cultured endothelial cells.
    Biological & pharmaceutical bulletin, 1994, Volume: 17, Issue:7

    Topics: Amino Acid Sequence; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Cattle; Cells, Cultured; Endothelins; Endothelium, Vascular; Indomethacin; Molecular Sequence Data; Nitric Oxide; Oligopeptides; Peptide Fragments; Platelet-Derived Growth Factor; RNA, Messenger; Tetrazoles; Tuna

1994
Infarct size reduction by AT1-receptor blockade through a signal cascade of AT2-receptor activation, bradykinin and prostaglandins in pigs.
    Journal of the American College of Cardiology, 1998, Nov-15, Volume: 32, Issue:6

    Topics: Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Bradykinin; Bradykinin Receptor Antagonists; Cyclooxygenase Inhibitors; Drug Combinations; Female; Imidazoles; Indomethacin; Male; Myocardial Infarction; Prostaglandins; Pyridines; Receptors, Angiotensin; Signal Transduction; Swine; Swine, Miniature; Tetrazoles

1998
Cardioprotective effect of angiotensin-converting enzyme inhibition against hypoxia/reoxygenation injury in cultured rat cardiac myocytes.
    Circulation, 1999, Feb-16, Volume: 99, Issue:6

    Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Bradykinin; Cell Hypoxia; Cells, Cultured; Cilazapril; Creatine Kinase; Cyclic GMP; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Guanidines; Indomethacin; Methylene Blue; Muscle Fibers, Skeletal; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxygen; Rats; Rats, Wistar; Staurosporine; Tetrazoles

1999
Bradykinin enhances sympathetic neurotransmission in rat blood vessels.
    Hypertension (Dallas, Tex. : 1979), 2002, Volume: 39, Issue:1

    Topics: Adenosine Triphosphate; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Bradykinin; Captopril; Cyclooxygenase Inhibitors; Drug Interactions; Excitatory Postsynaptic Potentials; In Vitro Techniques; Indomethacin; Male; Membrane Potentials; Mesenteric Arteries; Microelectrodes; Neuromuscular Junction; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Stimulation, Chemical; Sympathetic Nervous System; Synaptic Transmission; Tetrazoles

2002
Myogenic constriction is increased in mesenteric resistance arteries from rats with chronic heart failure: instantaneous counteraction by acute AT1 receptor blockade.
    British journal of pharmacology, 2003, Volume: 139, Issue:7

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Bridged Bicyclo Compounds, Heterocyclic; Captopril; Chronic Disease; Coronary Vessels; Disease Models, Animal; Endothelium-Dependent Relaxing Factors; Endothelium, Vascular; Fatty Acids, Unsaturated; Heart; Heart Failure; Hydrazines; Imidazoles; Indomethacin; Lisinopril; Losartan; Male; Mesenteric Arteries; Nitric Oxide; omega-N-Methylarginine; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Superoxide Dismutase; Sympathetic Nervous System; Tetrazoles; Tetrodotoxin; Vascular Resistance

2003
The renal vascular response to ANG II injection is reduced in the nonclipped kidney of two-kidney, one-clip hypertension.
    American journal of physiology. Renal physiology, 2005, Volume: 289, Issue:2

    Topics: Angiotensin II; Animals; Arginine Vasopressin; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blotting, Western; Cyclooxygenase Inhibitors; Down-Regulation; Hemodynamics; Hypertension, Renovascular; Indomethacin; Male; Organ Size; Proteins; Rats; Receptors, Angiotensin; Renal Circulation; Renin; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Tetrazoles; Vascular Resistance; Vasoconstrictor Agents

2005
A physicogenetic method to assign ligand-binding relationships between 7TM receptors.
    Bioorganic & medicinal chemistry letters, 2005, Aug-15, Volume: 15, Issue:16

    Topics: Animals; Benzimidazoles; Binding Sites; Binding, Competitive; Biphenyl Compounds; Cattle; Computer Simulation; Drug Design; Hydrocarbons, Aromatic; Indomethacin; Ligands; Models, Biological; Molecular Structure; Receptors, G-Protein-Coupled; Receptors, Immunologic; Receptors, Prostaglandin; Rhodopsin; Structure-Activity Relationship; Tetrazoles

2005
Angiotensin II-induced vasodilatation in cerebral arteries is mediated by endothelium-derived hyperpolarising factor.
    European journal of pharmacology, 2006, Feb-15, Volume: 531, Issue:1-3

    Topics: Adenosine Triphosphate; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apamin; Benzimidazoles; Biological Factors; Biphenyl Compounds; Cerebral Arteries; Charybdotoxin; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Imidazoles; In Vitro Techniques; Indomethacin; Male; Neurotoxins; Nitric Oxide Synthase; Nitroarginine; Pyridines; Rats; Rats, Sprague-Dawley; Serotonin; Tetrazoles; Vasoconstriction; Vasoconstrictor Agents

2006
[Angiotensin II AT1 receptor antagonists as antiinflammatory and gastric protection drugs].
    Acta gastroenterologica Latinoamericana, 2006, Volume: 36, Issue:2

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Inflammatory Agents; Benzimidazoles; Biphenyl Compounds; Carrageenan; Disease Models, Animal; Edema; Female; Gastric Mucosa; Indomethacin; Losartan; Rats; Rats, Wistar; Stomach Ulcer; Tetrazoles; Valine; Valsartan

2006
Vasodilatation of afferent arterioles and paradoxical increase of renal vascular resistance by furosemide in mice.
    American journal of physiology. Renal physiology, 2007, Volume: 293, Issue:1

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Arterioles; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cyclooxygenase Inhibitors; Diuretics; Dose-Response Relationship, Drug; Furosemide; Indomethacin; Kidney Tubules; Male; Mice; Mice, Inbred C57BL; Prostaglandins; Renal Circulation; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Tetrazoles; Urodynamics; Vascular Resistance; Vasodilation

2007
CV-11974, angiotensin II type I receptor antagonist, reduces the severity of indomethacin-induced rat enteritis.
    Digestive diseases and sciences, 2008, Volume: 53, Issue:3

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzimidazoles; Biphenyl Compounds; Chemokine CXCL1; Enteritis; Indomethacin; Intestinal Mucosa; Intestine, Small; Male; Peptic Ulcer; Peroxidase; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Tetrazoles; Thiobarbituric Acid Reactive Substances

2008
Gastroprotective effects of telmisartan on experimentally-induced gastric ulcers in rats.
    Die Pharmazie, 2009, Volume: 64, Issue:9

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Cold Temperature; Dinoprostone; Gastric Juice; Gastric Mucosa; Indomethacin; Male; Malondialdehyde; Nitric Oxide; Ranitidine; Rats; Rats, Wistar; Restraint, Physical; Stomach Ulcer; Stress, Psychological; Telmisartan; Tetrazoles

2009
Immunomodulatory effect of candesartan on indomethacin-induced gastric ulcer in rats.
    Immunopharmacology and immunotoxicology, 2012, Volume: 34, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Antioxidants; Benzimidazoles; Biphenyl Compounds; Cytokines; Dose-Response Relationship, Drug; Gastric Mucosa; Immunologic Factors; Indomethacin; Inflammation; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Tetrazoles; Th1 Cells

2012