candesartan and endothelin-1

candesartan has been researched along with endothelin-1 in 21 studies

Research

Studies (21)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	4 (19.05)	18.2507
2000's	15 (71.43)	29.6817
2010's	2 (9.52)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Eguchi, S; Hirata, Y; Kanno, K; Kano, H	1
Fukamizu, A; Hibi, K; Ishigami, T; Ishii, M; Kihara, M; Mizuno, K; Murakami, K; Nyui, N; Ochiai, H; Ohno, S; Tamura, K; Umemura, S; Yabana, M	1
Magga, J; Marttila, M; Ruskoaho, H; Vuolteenaho, O	1
Aikawa, R; Komuro, I; Kudoh, S; Nagai, R; Uozumi, H; Yamazaki, T; Yazaki, Y; Zou, Y	1
Ghiadoni, L; Magagna, A; Salvetti, A; Taddei, S; Virdis, A	1
Brenner, BM; Chertow, GM; Gurnani, A; Jiang, T; Mackenzie, HS; Rennke, HG; Shahsafaei, A; Taal, MW; Troy, JL	1
Derebail, VK; Pollock, DM; Pollock, JS; Yamamoto, T	1
Hautala, N; Ruskoaho, H; Szokodi, I; Tenhunen, O	1
Harada, S; Hatta, T; Kawa, T; Kido, H; Miki, S; Moriguchi, J; Morimoto, S; Nakagawa, M; Oguni, A; Sasaki, S; Takeda, K	1
Andersen, JL; Bie, P; Holstein-Rathlou, NH; Sandgaard, NC	1
deChâtel, R; Ilves, M; Kinnunen, P; Piuhola, J; Ruskoaho, H; Szokodi, I; Vuolteenaho, O	1
Elmarakby, AA; Morsing, P; Pollock, DM	1
Mäkinen, M; Piuhola, J; Ruskoaho, H; Szokodi, I	1
Biswas, P; Centracchio, J; Dworkin, LD; Gong, R; Roy, A; Tolbert, E; Yango, A	1
Cazaubon, S; Couraud, PO; Deshayes, F; Nahmias, C	1
Piuhola, J; Ruskoaho, H; Szokodi, I	1
Banes-Berceli, AK; Ketsawatsomkron, P; Marrero, MB; Ogbi, S; Patel, B; Pollock, DM	1
Afzal, R; Floras, J; McKelvie, RS; Rouleau, JL; White, M; Yusuf, S	1
Katovich, MJ; Mecca, AP; O'Connor, TE; Sumners, C	1
Albiston, AL; Chai, SY; Dupont, AG; Gembardt, F; Smolders, I; Vanderheyden, P; Walther, T; Yang, R	1
Kittikulsuth, W; Pollock, DM; Pollock, JS	1

Reviews

1 review(s) available for candesartan and endothelin-1

Article	Year
[Endothelin-1, angiotensin II and cancer]. Medecine sciences : M/S, 2006, Volume: 22, Issue:4 Topics: Angiogenesis Inhibitors; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antineoplastic Agents; Benzimidazoles; Biphenyl Compounds; Clinical Trials as Topic; Endothelin-1; Humans; Neoplasm Invasiveness; Neoplasms; Neovascularization, Pathologic; Receptors, Angiotensin; Receptors, Endothelin; Tetrazoles	2006

Article

Year

[Endothelin-1, angiotensin II and cancer].

Medecine sciences : M/S, 2006, Volume: 22, Issue:4

Topics: Angiogenesis Inhibitors; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antineoplastic Agents; Benzimidazoles; Biphenyl Compounds; Clinical Trials as Topic; Endothelin-1; Humans; Neoplasm Invasiveness; Neoplasms; Neovascularization, Pathologic; Receptors, Angiotensin; Receptors, Endothelin; Tetrazoles

2006

Trials

2 trial(s) available for candesartan and endothelin-1

Article	Year
Effect of the angiotensin II type 1 receptor blocker candesartan on endothelial function in patients with essential hypertension. Hypertension (Dallas, Tex. : 1979), 2000, Volume: 35, Issue:1 Pt 2 Topics: Acetylcholine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Female; Humans; Hypertension; Male; Middle Aged; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Peptides, Cyclic; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles; Vasoconstrictor Agents; Vasodilator Agents	2000
Effects of enalapril, candesartan or both on neurohumoral activation and LV volumes and function in patients with heart failure not treated with a beta-blocker. Therapeutic advances in cardiovascular disease, 2009, Volume: 3, Issue:2 Topics: Aged; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Double-Blind Method; Drug Therapy, Combination; Enalapril; Endothelin-1; Female; Heart Failure; Humans; Male; Middle Aged; Natriuretic Peptide, Brain; Norepinephrine; Peptide Fragments; Radionuclide Angiography; Stroke Volume; Tetrazoles; Treatment Outcome; Ventricular Function, Left	2009

Article

Year

Effect of the angiotensin II type 1 receptor blocker candesartan on endothelial function in patients with essential hypertension.

Hypertension (Dallas, Tex. : 1979), 2000, Volume: 35, Issue:1 Pt 2

Topics: Acetylcholine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Female; Humans; Hypertension; Male; Middle Aged; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Peptides, Cyclic; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles; Vasoconstrictor Agents; Vasodilator Agents

2000

Effects of enalapril, candesartan or both on neurohumoral activation and LV volumes and function in patients with heart failure not treated with a beta-blocker.

Therapeutic advances in cardiovascular disease, 2009, Volume: 3, Issue:2

Topics: Aged; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Double-Blind Method; Drug Therapy, Combination; Enalapril; Endothelin-1; Female; Heart Failure; Humans; Male; Middle Aged; Natriuretic Peptide, Brain; Norepinephrine; Peptide Fragments; Radionuclide Angiography; Stroke Volume; Tetrazoles; Treatment Outcome; Ventricular Function, Left

2009

Other Studies

18 other study(ies) available for candesartan and endothelin-1

Article	Year
Effect of an AT1 receptor antagonist (CV-11974) on angiotensin II-induced cardiomyocyte hypertrophy in vitro. Blood pressure. Supplement, 1994, Volume: 5 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blotting, Northern; Cardiomegaly; Cells, Cultured; DNA, Complementary; Endothelin-1; Endothelins; Heart; Imidazoles; Muscle, Smooth, Vascular; Myocardium; Protein Precursors; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Receptors, Endothelin; RNA, Messenger; Tetrazoles	1994
Stretch-induced MAP kinase activation in cardiomyocytes of angiotensinogen-deficient mice. Biochemical and biophysical research communications, 1997, Jun-09, Volume: 235, Issue:1 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Benzimidazoles; Biphenyl Compounds; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Activation; Gene Targeting; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Myocardium; Peptides, Cyclic; Renin-Angiotensin System; Tetrazoles	1997
Endothelin-1 is involved in stretch-induced early activation of B-type natriuretic peptide gene expression in atrial but not in ventricular myocytes: acute effects of mixed ET(A)/ET(B) and AT1 receptor antagonists in vivo and in vitro. Circulation, 1997, Nov-04, Volume: 96, Issue:9 Topics: Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Bosentan; Endothelin Receptor Antagonists; Endothelin-1; Gene Expression Regulation; Losartan; Male; Myocardium; Natriuretic Peptide, Brain; Nerve Tissue Proteins; Perfusion; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; RNA, Messenger; Sulfonamides; Tetrazoles	1997
Role of ion channels and exchangers in mechanical stretch-induced cardiomyocyte hypertrophy. Circulation research, 1998, Mar-09, Volume: 82, Issue:4 Topics: Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Calcium-Calmodulin-Dependent Protein Kinases; Cardiomegaly; Cytoplasm; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Guanidines; Hydrogen-Ion Concentration; Ion Channels; MAP Kinase Kinase 1; Mechanoreceptors; Mitogen-Activated Protein Kinase Kinases; Muscle Proteins; Peptides, Cyclic; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-raf; Rats; Rats, Wistar; Signal Transduction; Sodium-Hydrogen Exchangers; Sulfones; Tetrazoles	1998
Mechanisms underlying renoprotection during renin-angiotensin system blockade. American journal of physiology. Renal physiology, 2001, Volume: 280, Issue:2 Topics: Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Chemokine CCL2; Enalapril; Endothelin-1; Interleukin-1; Kidney Cortex; Kidney Failure, Chronic; Male; Nephrectomy; Proteinuria; Rats; Rats, Wistar; Renin-Angiotensin System; RNA, Messenger; Tetrazoles; Transforming Growth Factor beta; Transforming Growth Factor beta1	2001
Combined effects of AT(1) and ET(A) receptor antagonists, candesartan, and A-127722 in DOCA-salt hypertensive rats. General pharmacology, 2000, Volume: 34, Issue:5 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Atrasentan; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Body Weight; Desoxycorticosterone; Disease Models, Animal; Drug Therapy, Combination; Endothelin Receptor Antagonists; Endothelin-1; Hypertension; Kidney; Male; Natriuresis; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles	2000
Direct left ventricular wall stretch activates GATA4 binding in perfused rat heart: involvement of autocrine/paracrine pathways. Pflugers Archiv : European journal of physiology, 2002, Volume: 443, Issue:3 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Autocrine Communication; Benzimidazoles; Biphenyl Compounds; Bosentan; Catheterization; DNA-Binding Proteins; Endothelin Receptor Antagonists; Endothelin-1; GATA4 Transcription Factor; In Vitro Techniques; Male; Myocardium; Paracrine Communication; Perfusion; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Sulfonamides; Tetrazoles; Transcription Factor AP-1; Transcription Factors; Ventricular Function	2002
Comparative effects of candesartan and enalapril on augmented vasoconstrictive responses to endothelin-1 in coronary vessels of spontaneously hypertensive rats. American journal of hypertension, 2002, Volume: 15, Issue:3 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cardiomegaly; Coronary Vessels; Dose-Response Relationship, Drug; Enalapril; Endothelin-1; Hypertension; In Vitro Techniques; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles; Vascular Resistance; Vasoconstriction	2002
Aortic blood flow subtraction: an alternative method for measuring total renal blood flow in conscious dogs. American journal of physiology. Regulatory, integrative and comparative physiology, 2002, Volume: 282, Issue:5 Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta, Abdominal; Arterial Occlusive Diseases; Benzimidazoles; Biphenyl Compounds; Blood Flow Velocity; Blood Pressure; Carotid Arteries; Dogs; Endothelin-1; Female; Homeostasis; Regional Blood Flow; Renal Artery; Renal Circulation; Reproducibility of Results; Rheology; Subtraction Technique; Tetrazoles; Ultrasonography; Vascular Resistance; Vasoconstrictor Agents	2002
Endothelin-1 contributes to the Frank-Starling response in hypertrophic rat hearts. Hypertension (Dallas, Tex. : 1979), 2003, Volume: 41, Issue:1 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Animals, Genetically Modified; Benzimidazoles; Biphenyl Compounds; Bosentan; Endothelin Receptor Antagonists; Endothelin-1; Heart Ventricles; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Myocardial Contraction; Organ Culture Techniques; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin; RNA, Messenger; Stress, Mechanical; Sulfonamides; Tetrazoles	2003
Enalapril attenuates endothelin-1-induced hypertension via increased kinin survival. American journal of physiology. Heart and circulatory physiology, 2003, Volume: 284, Issue:6 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Bradykinin Receptor Antagonists; Enalapril; Endothelin-1; Glomerular Filtration Rate; Hematocrit; Hypertension; Kinins; Male; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Bradykinin B2; Receptors, Angiotensin; Tetrazoles; Urodynamics	2003
Dual role of endothelin-1 via ETA and ETB receptors in regulation of cardiac contractile function in mice. American journal of physiology. Heart and circulatory physiology, 2003, Volume: 285, Issue:1 Topics: Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Bosentan; Coronary Circulation; Coronary Vessels; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Heart Rate; In Vitro Techniques; Male; Mice; Myocardial Contraction; Oligopeptides; Peptides, Cyclic; Piperidines; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Sulfonamides; Tetrazoles	2003
Hepatocyte growth factor induces an endothelin-mediated decline in glomerular filtration rate. American journal of physiology. Renal physiology, 2005, Volume: 288, Issue:1 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Bosentan; Cattle; Cells, Cultured; Drug Administration Schedule; Endothelin-1; Glomerular Filtration Rate; Hepatocyte Growth Factor; Kidney; Kidney Glomerulus; Male; Rats; Rats, Sprague-Dawley; Sulfonamides; Tetrazoles	2005
Endothelin-1 and angiotensin II contribute to BNP but not c-fos gene expression response to elevated load in isolated mice hearts. Biochimica et biophysica acta, 2007, Volume: 1772, Issue:3 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Coronary Circulation; Endothelin Receptor Antagonists; Endothelin-1; Gene Expression; Gene Expression Regulation; Genes, fos; Heart; Heart Ventricles; In Vitro Techniques; Male; Mice; Natriuretic Peptide, Brain; Receptor, Angiotensin, Type 1; Tetrazoles; Up-Regulation	2007
Angiotensin II and endothelin-1 augment the vascular complications of diabetes via JAK2 activation. American journal of physiology. Heart and circulatory physiology, 2007, Volume: 293, Issue:2 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Thoracic; Atrasentan; Benzimidazoles; Biphenyl Compounds; Blood Glucose; Blood Pressure; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Endothelin A Receptor Antagonists; Endothelin-1; Enzyme Activation; Intracellular Signaling Peptides and Proteins; Janus Kinase 2; Male; Phosphorylation; Protein Kinase Inhibitors; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Pyrrolidines; Rats; Receptor, Angiotensin, Type 1; Receptor, Endothelin A; Signal Transduction; STAT1 Transcription Factor; STAT3 Transcription Factor; Tetrazoles; Time Factors; Tyrphostins; Vasodilation	2007
Candesartan pretreatment is cerebroprotective in a rat model of endothelin-1-induced middle cerebral artery occlusion. Experimental physiology, 2009, Volume: 94, Issue:8 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Brain Ischemia; Cerebral Infarction; Disease Models, Animal; Endothelin-1; Infarction, Middle Cerebral Artery; Male; Rats; Rats, Sprague-Dawley; Stroke; Tetrazoles	2009
Renal vasoconstrictor and pressor responses to angiotensin IV in mice are AT1a-receptor mediated. Journal of hypertension, 2010, Volume: 28, Issue:3 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Base Sequence; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Body Weight; DNA Primers; Endothelin-1; Hemodynamics; Kidney; Mice; Mice, Inbred C57BL; Mice, Knockout; Organ Size; Receptor, Angiotensin, Type 1; Tetrazoles; Vasoconstriction	2010
Loss of renal medullary endothelin B receptor function during salt deprivation is regulated by angiotensin II. American journal of physiology. Renal physiology, 2012, Volume: 303, Issue:5 Topics: Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Diet, Sodium-Restricted; Diuresis; Endothelin-1; Endothelin-2; Kidney Medulla; Male; Natriuresis; Rats; Rats, Sprague-Dawley; Receptor, Endothelin B; Sodium Chloride, Dietary; Sodium, Dietary; Tetrazoles; Viper Venoms	2012