candesartan has been researched along with enalapril in 59 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 6 (10.17) | 18.2507 |
2000's | 36 (61.02) | 29.6817 |
2010's | 16 (27.12) | 24.3611 |
2020's | 1 (1.69) | 2.80 |
Authors | Studies |
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Funakoshi, J; Kakumoto, M; Okumura, K; Sakaeda, T; Takara, K; Tanigawara, Y | 1 |
Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Hamar, P; Heemann, U; Kovács, G; Peti-Peterdi, J; Rázga, Z; Rosivall, L | 1 |
Brenner, BM; Taal, MW | 1 |
Brenner, BM; Kato, S; Lee, KW; Luyckx, VA; MacKenzie, HS; Ots, M; Troy, JL; Ziai, F | 1 |
Avezum, A; Burns, RJ; Latini, R; Maggioni, A; McKelvie, RS; Pericak, D; Pogue, J; Probstfield, J; Rouleau, J; Tsuyuki, RT; White, M; Young, J; Yusuf, S | 1 |
Riegger, GA | 1 |
Rapezzi, C | 1 |
Inada, Y; Nishikawa, K; Ojima, M; Sanada, T; Shibouta, Y; Wada, T | 1 |
Berlowitz, M; Ennezat, PV; Le Jemtel, TH; Sonnenblick, EH | 1 |
Hoagland, KM; Ito, O; Ito, S; Omata, K; Roman, RJ | 1 |
Brenner, BM; Chertow, GM; Gurnani, A; Jiang, T; Mackenzie, HS; Rennke, HG; Shahsafaei, A; Taal, MW; Troy, JL | 1 |
Abe, I; Kagiyama, S; Lin, Y; Matsumura, K; Tsuchihashi, T | 1 |
Demers, C; McKelvie, RS; Negassa, A; Yusuf, S | 1 |
Mohr, FW; Olbrich, HG; Richter, H; Richter, M; Skupin, M | 1 |
Achard, JM; Allard, J; Dalmay, F; Fournier, A; Mazouz, H; Pesteil, F | 1 |
Harada, S; Hatta, T; Kawa, T; Kido, H; Miki, S; Moriguchi, J; Morimoto, S; Nakagawa, M; Oguni, A; Sasaki, S; Takeda, K | 1 |
Rapi, J | 1 |
Abe, I; Fujii, K | 1 |
Agabiti-Rosei, E; Cuspidi, C; Di Biagio, C; Magnani, B; Muiesan, ML; Salvetti, M; Valagussa, L; Zanchetti, A | 1 |
Elmarakby, AA; Morsing, P; Pollock, DM | 1 |
Jacobsen, P; Parving, HH; Pietraszek, L; Rossing, K | 1 |
Afzal, R; Held, P; Maggioni, AP; McKelvie, RS; Rouleau, JL; White, M; Young, JB; Yusuf, S | 1 |
Kokkinos, P; Narayan, P; Papademetriou, V | 1 |
Lackland, DT | 1 |
Leelasa-nguan, P; Phakdeekitcharoen, B | 1 |
De Prez, EG; Debelle, FD; Deschodt-Lanckman, MM; Husson, CP; Nortier, JL; Rombaut, K; Salmon, IJ; Vanherweghem, JL; Vienne, AR | 1 |
Komuro, I; Kuwabara, Y | 1 |
Cohen-Solal, A; Dietz, R; Eichhorn, E; Erhardt, L; Hobbs, FD; Krum, H; Maggioni, A; McKelvie, RS; McMurray, J; Piña, IL; Soler-Soler, J; Swedberg, K | 1 |
Afzal, R; Floras, J; Hall, C; Latini, R; Maggioni, AP; Masson, S; McKelvie, RS; Rouleau, JL; White, M; Yan, AT; Yan, RT; Yusuf, S | 1 |
Dellgren, G; Fischer, H; Grinnemo, KH; Gustafsson, T; Hao, X; Mansson-Broberg, A; Siddiqui, AJ; Sylvén, C | 1 |
Hamai, M; Horiuchi, M; Ide, A; Iwai, M; Mogi, M; Tomochika, H; Tomono, Y | 1 |
Briggs, JP; Chen, L; Huang, YG; Kim, SM; Mizel, D; Schnermann, J | 1 |
Abitbol, C; Chandar, J; Montané, B; Zilleruelo, G | 1 |
Elewa, HF; Ergul, A; Fagan, SC; Johnson, MH; Kozak, A | 1 |
Idikio, H; Jugdutt, BI; Uwiera, RR | 1 |
Kato, N; Liang, YQ; Ochiai, Y; Serizawa, M | 1 |
Hayashi, K; Ishiguro, K; Itoh, H; Sakamaki, Y; Sasamura, H | 1 |
Ciulla, MM; Cuspidi, C; Esposito, A; Magrini, F; Muiesan, ML; Paliotti, R; Rosei, EA; Zanchetti, A | 1 |
Afzal, R; Floras, J; McKelvie, RS; Rouleau, JL; White, M; Yusuf, S | 1 |
Ageev, FT; Ovchinnikov, AG; Serbul, VM | 1 |
Frimodt-Møller, M; Høj Nielsen, A; Kamper, AL; Strandgaard, S | 1 |
Briggs, JP; Chen, L; Chen, M; Eisner, C; Gomez, RA; Huang, Y; Kim, SM; Li, L; Mizel, D; Oppermann, M; Schnermann, J; Sequeira Lopez, ML; Weinstein, LS | 1 |
Apablaza, F; Chiong, M; Godoy, I; Gonzalez, L; Hernandez, C; Jalil, JE; Lavandero, S; Lopez, R; Moya, J; Novoa, U; Ocaranza, MP; Pinto, M; Varas, M; Verdejo, H | 1 |
Naviglio, S; Pirozzi, F | 1 |
Dodson, P; Hobbs, FR; Sjølie, AK | 1 |
Fagan, SC; Guan, W; Kozak, A | 1 |
Frimodt-Møller, M; Kamper, AL; Kreiner, S; Nielsen, AH; Strandgaard, S | 1 |
Boomsma, F; Danser, AH; Schilders, JE; van den Meiracker, AH; Wu, H | 1 |
Bodegård, J; Hammar, N; Hasvold, LP; Kjeldsen, SE; Russell, D; Stålhammar, J; Sundström, J; Thuresson, M | 1 |
Andersen, K; Arango, JL; Arnold, M; Bayram, E; Bĕlohlávek, J; Böhm, M; Boytsov, S; Burgess, L; Cabrera, W; Chen, CH; Desai, A; Erglis, A; Fu, M; Gomez, E; Gong, J; Gonzalez, A; Greenlaw, N; Hagege, AA; Katova, T; Kiatchoosakun, S; Kim, KS; Lefkowitz, M; Martinez, F; McMurray, J; Mendoza, I; Merkely, B; Mosterd, A; Negrusz-Kawecka, M; Packer, M; Peuhkurinen, K; Ramires, F; Refsgaard, J; Rizkala, A; Rouleau, J; Senni, M; Shi, V; Sibulo, AS; Silva-Cardoso, J; Solomon, S; Squire, I; Starling, RC; Swedberg, K; Teerlink, JR; Vinereanu, D; Wong, R; Zile, MR | 1 |
Bratlie, SO; Casselbrant, A; Edebo, A; Fändriks, L | 1 |
Danilov, SM; Dull, RO; Schwartz, DE; Tovsky, SI | 1 |
Basbugan, Y; Demir, CY; Ersoz, ME; Erten, R; Kocak, OF; Sultanoglu, Y | 1 |
Bratlie, SO; Casselbrant, A; Edebo, A; Fändriks, L; Wallenius, V | 1 |
Fan, Y; Hu, G; Ito, O; Kohzuki, M; Ma, Y; Miura, T; Qiu, J; Xu, L | 1 |
8 review(s) available for candesartan and enalapril
Article | Year |
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DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
ACE-I vs angiotensin II receptor antagonists: prevention of renal injury in chronic rat models.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Bradykinin; Chronic Disease; Disease Models, Animal; Enalapril; Follow-Up Studies; Glomerulosclerosis, Focal Segmental; Hypertension, Renal; Peptidyl-Dipeptidase A; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Treatment Outcome | 1999 |
[ACE inhibitors or AT1 receptor antagonists?].
Topics: Age Factors; Aged; Angiotensin I; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Captopril; Clinical Trials as Topic; Death, Sudden, Cardiac; Enalapril; Heart Failure; Humans; Losartan; Prodrugs; Prognosis; Randomized Controlled Trials as Topic; Risk Factors; Tetrazoles; Time Factors | 1999 |
Therapeutic implications of escape from angiotensin-converting enzyme inhibition in patients with chronic heart failure.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Drug Therapy, Combination; Enalapril; Heart Failure; Humans; Randomized Controlled Trials as Topic; Tetrazoles; Ventricular Dysfunction, Left | 2000 |
[Irbesartan: a new possibility in the treatment of hypertension].
Topics: Acrylates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Atenolol; Benzimidazoles; Benzoates; Biological Availability; Biphenyl Compounds; Controlled Clinical Trials as Topic; Drug Administration Schedule; Enalapril; Half-Life; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan | 2002 |
[Angiotensin II receptor antagonist improves age-related impairment of EDHF-mediated hyperpolarization].
Topics: Aging; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biological Factors; Biphenyl Compounds; Enalapril; Humans; Hypertension; Rats; Tetrazoles | 2002 |
[Ace inhibitors and angiotensin II receptor antagonists for therapy of chronic heart failure].
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Clinical Trials as Topic; Enalapril; Heart Failure; Humans; Indoles; Lisinopril; Losartan; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan | 2005 |
Does renin-angiotensin system blockade have a role in preventing diabetic retinopathy? A clinical review.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Clinical Trials as Topic; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Enalapril; Humans; Losartan; Renin-Angiotensin System; Tetrazoles | 2011 |
19 trial(s) available for candesartan and enalapril
Article | Year |
---|---|
Comparison of candesartan, enalapril, and their combination in congestive heart failure: randomized evaluation of strategies for left ventricular dysfunction (RESOLVD) pilot study. The RESOLVD Pilot Study Investigators.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Creatinine; Drug Combinations; Enalapril; Female; Heart Failure; Heart Rate; Hormones; Humans; Male; Middle Aged; Pilot Projects; Potassium; Tetrazoles; Ventricular Dysfunction, Left; Ventricular Function | 1999 |
[Comparison of candesartan, enalapril and their combination in congestive heart failure].
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Double-Blind Method; Drug Therapy, Combination; Enalapril; Follow-Up Studies; Heart Failure; Humans; Pilot Projects; Prospective Studies; Quality of Life; Tetrazoles; Time Factors | 2000 |
Reliability, validity, and responsiveness of the six-minute walk test in patients with heart failure.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Drug Therapy, Combination; Enalapril; Exercise Test; Female; Health Status; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Pilot Projects; Quality of Life; Reproducibility of Results; Sickness Impact Profile; Stroke Volume; Surveys and Questionnaires; Tetrazoles; Treatment Outcome; Ventricular Function, Left; Walking | 2001 |
Comparative effects of candesartan and enalapril on left ventricular hypertrophy in patients with essential hypertension: the candesartan assessment in the treatment of cardiac hypertrophy (CATCH) study.
Topics: Adult; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Echocardiography; Enalapril; Female; Heart Rate; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Tetrazoles; Treatment Outcome | 2002 |
Renoprotective effects of adding angiotensin II receptor blocker to maximal recommended doses of ACE inhibitor in diabetic nephropathy: a randomized double-blind crossover trial.
Topics: Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Captopril; Cross-Over Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Double-Blind Method; Drug Therapy, Combination; Enalapril; Female; Humans; Kidney; Lisinopril; Male; Middle Aged; Tetrazoles; Treatment Outcome | 2003 |
Comparative impact of enalapril, candesartan or metoprolol alone or in combination on ventricular remodelling in patients with congestive heart failure.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cardiac Volume; Double-Blind Method; Drug Therapy, Combination; Enalapril; Female; Heart Failure; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Stroke Volume; Survival Analysis; Tetrazoles; Treatment Outcome; Ventricular Remodeling | 2003 |
Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in African-American patients with hypertension.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Black or African American; Blood Pressure; Cross-Over Studies; Drug Therapy, Combination; Enalapril; Hospitals, Veterans; Humans; Hypertension; Middle Aged; Tetrazoles; Treatment Outcome | 2004 |
Effects of an ACE inhibitor or angiotensin receptor blocker on potassium in CAPD patients.
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Cross-Over Studies; Enalapril; Female; Homeostasis; Humans; Hyperkalemia; Kidney Failure, Chronic; Male; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Potassium; Tetrazoles | 2004 |
Usefulness of temporal changes in neurohormones as markers of ventricular remodeling and prognosis in patients with left ventricular systolic dysfunction and heart failure receiving either candesartan or enalapril or both.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biomarkers; Biphenyl Compounds; Cardiac Output; Chromatography, High Pressure Liquid; Double-Blind Method; Drug Therapy, Combination; Enalapril; Female; Heart Failure; Humans; Male; Middle Aged; Neurotransmitter Agents; Prognosis; Systole; Tetrazoles; Treatment Outcome; Ventricular Dysfunction, Left; Ventricular Remodeling | 2005 |
Effects of antihypertensive treatment on ultrasound measures of myocardial fibrosis in hypertensive patients with left ventricular hypertrophy: results of a randomized trial comparing the angiotensin receptor antagonist, candesartan and the angiotensin-co
Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Enalapril; Female; Fibrosis; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Myocardium; Tetrazoles; Treatment Outcome; Ultrasonography | 2009 |
Effects of enalapril, candesartan or both on neurohumoral activation and LV volumes and function in patients with heart failure not treated with a beta-blocker.
Topics: Aged; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Double-Blind Method; Drug Therapy, Combination; Enalapril; Endothelin-1; Female; Heart Failure; Humans; Male; Middle Aged; Natriuretic Peptide, Brain; Norepinephrine; Peptide Fragments; Radionuclide Angiography; Stroke Volume; Tetrazoles; Treatment Outcome; Ventricular Function, Left | 2009 |
[Effects of renin-angiotensin system blockers on left ventricular hypertrophy and biochemical markers of collagen balance in patients with hypertensive hypertrophy].
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Biomarkers; Biphenyl Compounds; Blood Pressure; Collagen; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enalapril; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Matrix Metalloproteinase 1; Middle Aged; Renin-Angiotensin System; Tetrazoles; Tissue Inhibitor of Metalloproteinase-1; Treatment Outcome | 2009 |
Feasibility of combined treatment with enalapril and candesartan in advanced chronic kidney disease.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Chronic Disease; Disease Progression; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enalapril; Feasibility Studies; Female; Glomerular Filtration Rate; Humans; Kidney Diseases; Male; Middle Aged; Renin-Angiotensin System; Tetrazoles | 2010 |
Beneficial effects on arterial stiffness and pulse-wave reflection of combined enalapril and candesartan in chronic kidney disease--a randomized trial.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cross-Over Studies; Drug Therapy, Combination; Enalapril; Female; Humans; Hypertension; Kidney; Male; Middle Aged; Pulse Wave Analysis; Renal Insufficiency, Chronic; Tetrazoles; Vascular Stiffness | 2012 |
Renin-angiotensin system phenotyping as a guidance toward personalized medicine for ACE inhibitors: can the response to ACE inhibition be predicted on the basis of plasma renin or ACE?
Topics: Aged; Aldosterone; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cross-Over Studies; Diuretics; Double-Blind Method; Drug Therapy, Combination; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Peptidyl-Dipeptidase A; Phenotype; Precision Medicine; Renin; Renin-Angiotensin System; Tetrazoles | 2014 |
A putative placebo analysis of the effects of LCZ696 on clinical outcomes in heart failure.
Topics: Aged; Aminobutyrates; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Drug Combinations; Enalapril; Female; Heart Failure; Hospitalization; Humans; Male; Middle Aged; Placebo Effect; Tetrazoles; Treatment Outcome; Valsartan | 2015 |
Support for involvement of the renin-angiotensin system in dysplastic Barrett's esophagus.
Topics: Adenocarcinoma; Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Barrett Esophagus; Benzimidazoles; Biomarkers, Tumor; Biphenyl Compounds; Enalapril; Endoscopy; Esomeprazole; Esophageal Neoplasms; Female; Humans; Hyperplasia; Male; Middle Aged; Neoplasm Proteins; Nitric Oxide Synthase Type II; Precancerous Conditions; Prospective Studies; Proton Pump Inhibitors; Renin-Angiotensin System; Risk Factors; Sweden; Tertiary Care Centers; Tetrazoles | 2017 |
ACE Phenotyping as a Guide Toward Personalized Therapy With ACE Inhibitors.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cross-Over Studies; Double-Blind Method; Drug Monitoring; Drug Resistance; Drug Therapy, Combination; Enalapril; Genotype; Humans; Hydrochlorothiazide; Hypertension; Patient Selection; Peptidyl-Dipeptidase A; Pharmacogenetics; Pharmacogenomic Testing; Pharmacogenomic Variants; Phenotype; Precision Medicine; Predictive Value of Tests; Sodium Chloride Symporter Inhibitors; Tetrazoles; Treatment Outcome | 2017 |
Proteomic Approach to the Potential Role of Angiotensin II in Barrett Dysplasia.
Topics: Adult; Aged; Angiotensin II; Barrett Esophagus; Benzimidazoles; Biopsy; Biphenyl Compounds; Enalapril; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Neoplasm Proteins; Proteomics; Tetrazoles | 2019 |
32 other study(ies) available for candesartan and enalapril
Article | Year |
---|---|
Interaction of digoxin with antihypertensive drugs via MDR1.
Topics: Animals; Antihypertensive Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cells, Cultured; Digoxin; Drug Interactions; Humans; Time Factors | 2002 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Coinhibition of immune and renin-angiotensin systems reduces the pace of glomerulosclerosis in the rat remnant kidney.
Topics: Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cholesterol; Disease Models, Animal; Enalapril; Glomerulosclerosis, Focal Segmental; Immune System; Immunosuppressive Agents; Interleukin-2; Kidney; Male; Nephrectomy; Proteinuria; Rats; Rats, Wistar; Renin-Angiotensin System; Tacrolimus; Tetrazoles; Triglycerides | 1999 |
Renin-angiotensin blockade lowers MCP-1 expression in diabetic rats.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Base Sequence; Benzimidazoles; Biphenyl Compounds; Chemokine CCL2; Cytokines; Diabetes Mellitus, Experimental; Diabetic Nephropathies; DNA Primers; Enalapril; Gene Expression; Growth Substances; Kidney Glomerulus; Macrophages; Male; Proteinuria; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazoles | 1999 |
Comparison of the antihypertensive effects of the new angiotensin II (AT1) receptor antagonist candesartan cilexetil (TCV-116) and the angiotensin converting enzyme inhibitor enalapril in rats.
Topics: Administration, Oral; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Bradykinin; Enalapril; Enzyme Activation; Hypertension, Renal; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renal Artery; Surgical Instruments; Tetrazoles; Vasoconstrictor Agents | 1996 |
Effects of converting enzyme inhibitors on renal P-450 metabolism of arachidonic acid.
Topics: 8,11,14-Eicosatrienoic Acid; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Arachidonic Acid; Benzimidazoles; Biphenyl Compounds; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Enalapril; Enzyme Inhibitors; Hydroxyeicosatetraenoic Acids; Kidney; Kidney Cortex; Kidney Medulla; Male; Microsomes; Mixed Function Oxygenases; NADPH-Ferrihemoprotein Reductase; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Spironolactone; Tetrazoles | 2001 |
Mechanisms underlying renoprotection during renin-angiotensin system blockade.
Topics: Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Chemokine CCL2; Enalapril; Endothelin-1; Interleukin-1; Kidney Cortex; Kidney Failure, Chronic; Male; Nephrectomy; Proteinuria; Rats; Rats, Wistar; Renin-Angiotensin System; RNA, Messenger; Tetrazoles; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2001 |
The influence of chronic antihypertensive treatment on the central pressor response in SHR.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Body Weight; Brain; Enalapril; Epinephrine; Heart Rate; Hydralazine; Hydrochlorothiazide; Hypertension; Injections, Intraventricular; Losartan; Male; Norepinephrine; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Saline Solution, Hypertonic; Tetrazoles | 2001 |
Do vascular compartments differ in the development of chronic rejection? AT(1) blocker candesartan versus Ace blocker enalapril in an experimental heart transplant model.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Cyclosporine; Enalapril; Graft Rejection; Heart Transplantation; Hemodynamics; Immunosuppressive Agents; Models, Animal; Preoperative Care; Rats; Rats, Inbred F344; Rats, Inbred Lew; Tetrazoles | 2001 |
Non-AT(1)-receptor-mediated protective effect of angiotensin against acute ischaemic stroke in the gerbil.
Topics: Acute Disease; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Brain Ischemia; Disease Models, Animal; Enalapril; Gerbillinae; Lisinopril; Losartan; Male; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Reproducibility of Results; Stroke; Tetrazoles | 2001 |
Comparative effects of candesartan and enalapril on augmented vasoconstrictive responses to endothelin-1 in coronary vessels of spontaneously hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cardiomegaly; Coronary Vessels; Dose-Response Relationship, Drug; Enalapril; Endothelin-1; Hypertension; In Vitro Techniques; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles; Vascular Resistance; Vasoconstriction | 2002 |
Enalapril attenuates endothelin-1-induced hypertension via increased kinin survival.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Bradykinin Receptor Antagonists; Enalapril; Endothelin-1; Glomerular Filtration Rate; Hematocrit; Hypertension; Kinins; Male; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Bradykinin B2; Receptors, Angiotensin; Tetrazoles; Urodynamics | 2003 |
Hypertension control among African Americans: an urgent call for action.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Black or African American; Drug Therapy, Combination; Enalapril; Humans; Hypertension; Randomized Controlled Trials as Topic; Tetrazoles | 2004 |
The renin-angiotensin system blockade does not prevent renal interstitial fibrosis induced by aristolochic acids.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Aristolochic Acids; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Diet, Sodium-Restricted; Drug Synergism; Enalapril; Fibrosis; Kidney; Kidney Diseases; Male; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Renin-Angiotensin System; Tetrazoles | 2004 |
Practical recommendations for the use of ACE inhibitors, beta-blockers, aldosterone antagonists and angiotensin receptor blockers in heart failure: putting guidelines into practice.
Topics: Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Benzopyrans; Biphenyl Compounds; Bisoprolol; Captopril; Carbazoles; Carvedilol; Drug Therapy, Combination; Enalapril; Ethanolamines; Evidence-Based Medicine; Guideline Adherence; Heart Failure; Humans; Indoles; Lisinopril; Metoprolol; Mineralocorticoid Receptor Antagonists; Nebivolol; Practice Guidelines as Topic; Propanolamines; Ramipril; Spironolactone; Stroke Volume; Tetrazoles; Valine; Valsartan | 2005 |
Antagonism of the renin-angiotensin system can counteract cardiac angiogenic vascular endothelial growth factor gene therapy and myocardial angiogenesis in the normal heart.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Capillaries; Coronary Vessels; Enalapril; Genetic Therapy; Luciferases; Male; Mice; Mice, Inbred C57BL; Neovascularization, Physiologic; Renin-Angiotensin System; Tetrazoles; Vascular Endothelial Growth Factor A | 2005 |
Comparison of inhibitory action of candesartan and enalapril on brain ischemia through inhibition of oxidative stress.
Topics: Analysis of Variance; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Brain; Brain Ischemia; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Enalapril; Histocompatibility Antigens; Immunohistochemistry; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Superoxides; Tetrazoles; Tetrazolium Salts | 2006 |
Low plasma renin and reduced renin secretory responses to acute stimuli in conscious COX-2-deficient mice.
Topics: Adrenergic beta-Agonists; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cells, Cultured; Cyclooxygenase 2; Diet, Sodium-Restricted; Diuretics; Enalapril; Furosemide; Isoproterenol; Juxtaglomerular Apparatus; Mice; Mice, Inbred C57BL; Mice, Knockout; Renin; Reverse Transcriptase Polymerase Chain Reaction; RNA; Telemetry; Tetrazoles | 2007 |
Angiotensin blockade as sole treatment for proteinuric kidney disease in children.
Topics: Adolescent; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Child; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enalapril; Female; Glomerular Filtration Rate; Humans; Kidney Diseases; Losartan; Male; Proteinuria; Retrospective Studies; Tetrazoles | 2007 |
Blood pressure lowering after experimental cerebral ischemia provides neurovascular protection.
Topics: Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Area Under Curve; Benzimidazoles; Biomarkers; Biphenyl Compounds; Blood Pressure; Brain Ischemia; Cerebrovascular Circulation; Circadian Rhythm; Disease Models, Animal; Dose-Response Relationship, Drug; Enalapril; Hemoglobins; Hydralazine; Infarction, Middle Cerebral Artery; Male; Rats; Rats, Wistar; Reperfusion; Telemetry; Tetrazoles | 2007 |
Angiotensin receptor blockade and angiotensin-converting-enzyme inhibition limit adverse remodeling of infarct zone collagens and global diastolic dysfunction during healing after reperfused ST-elevation myocardial infarction.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Collagen; Dogs; Enalapril; Hydroxyproline; Myocardial Infarction; Myocardial Reperfusion; Peptidyl-Dipeptidase A; Tetrazoles; Transforming Growth Factor beta1; Ventricular Dysfunction, Left; Ventricular Remodeling; Wound Healing | 2007 |
Dynamic changes of the renin-angiotensin and associated systems in the rat after pharmacological and dietary interventions in vivo.
Topics: Animals; Benzimidazoles; Biphenyl Compounds; Dietary Fats; Diuretics; Enalapril; Gene Expression Regulation; Hydrochlorothiazide; Male; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium Chloride, Dietary; Tetrazoles | 2008 |
"Pulse" treatment with high-dose angiotensin blocker reverses renal arteriolar hypertrophy and regresses hypertension.
Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Arterioles; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Disease Models, Animal; Dose-Response Relationship, Drug; Enalapril; Hydralazine; Hypertension; Hypertrophy; Kidney; Male; Matrix Metalloproteinase 13; Nifedipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; Tetrazoles; Vasodilator Agents | 2009 |
Stimulation of renin secretion by angiotensin II blockade is Gsalpha-dependent.
Topics: Adenylyl Cyclases; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Captopril; Catecholamines; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enalapril; Female; GTP-Binding Protein alpha Subunits, Gs; Juxtaglomerular Apparatus; Male; Mice; Mice, Knockout; Models, Animal; Nitric Oxide; Prostaglandins; Renin; Signal Transduction; Tetrahydroisoquinolines; Tetrazoles | 2010 |
Angiotensin-(1-9) regulates cardiac hypertrophy in vivo and in vitro.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Bradykinin; Cardiomegaly; Cell Enlargement; Cells, Cultured; Enalapril; Humans; Hypertrophy, Left Ventricular; In Vitro Techniques; Insulin-Like Growth Factor I; Male; Myocardial Infarction; Myocytes, Cardiac; Norepinephrine; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Tetrazoles; Ventricular Function, Left | 2010 |
Renin-Angiotensin system blockade for diabetic nephropathy prevention.
Topics: Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Enalapril; Female; Humans; Losartan; Male; Prognosis; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Risk Assessment; Tetrazoles; Treatment Outcome | 2010 |
Drug repurposing for vascular protection after acute ischemic stroke.
Topics: Animals; Anticholesteremic Agents; Antihypertensive Agents; Atorvastatin; Benzimidazoles; Biphenyl Compounds; Brain Infarction; Diabetes Mellitus, Type 2; Disease Models, Animal; Enalapril; Enzyme-Linked Immunosorbent Assay; Functional Laterality; Hemoglobins; Hemorrhage; Heptanoic Acids; Male; Matrix Metalloproteinase 9; Pyrroles; Rats; Rats, Inbred SHR; Rats, Wistar; Reperfusion; Stroke; Tetrazoles; Vascular System Injuries | 2011 |
Diabetes and CVD risk during angiotensin-converting enzyme inhibitor or angiotensin II receptor blocker treatment in hypertension: a study of 15,990 patients.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Enalapril; Female; Humans; Hypertension; Incidence; Male; Middle Aged; Primary Health Care; Retrospective Studies; Risk Factors; Sweden; Tetrazoles; Time Factors; Treatment Outcome | 2014 |
Comparison of Enalapril, Candesartan and Intralesional Triamcinolone in Reducing Hypertrophic Scar Development: An Experimental Study.
Topics: Administration, Oral; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biopsy, Needle; Biphenyl Compounds; Chi-Square Distribution; Cicatrix, Hypertrophic; Disease Models, Animal; Enalapril; Follow-Up Studies; Immunohistochemistry; Injections, Intralesional; Male; Rabbits; Random Allocation; Risk Assessment; Tetrazoles; Treatment Outcome; Triamcinolone | 2018 |
High Fructose-Induced Hypertension and Renal Damage Are Exaggerated in Dahl Salt-Sensitive Rats via Renal Renin-Angiotensin System Activation.
Topics: Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Enalapril; Fructose; Hypertension; Kidney Glomerulus; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Dahl; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Sodium, Dietary; Tetrazoles | 2021 |