candesartan and avapro

candesartan has been researched along with avapro in 92 studies

Research

Studies (92)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	8 (8.70)	18.2507
2000's	41 (44.57)	29.6817
2010's	33 (35.87)	24.3611
2020's	10 (10.87)	2.80

Authors

Authors	Studies
Goldberg, MR; Greenlee, WJ; Irvin, JD; Prendergast, K; Smith, RD; Timmermans, PB; Wexler, RR	1
De Backer, JP; Fierens, FL; Fraeyman, N; Vanderheyden, PM; Vauquelin, G	1
Schieffer, B; Schmidt, B	1
Berellini, G; Cruciani, G; Mannhold, R	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Giridhar, R; Murumkar, P; Naik, P; Yadav, MR	1
Fukami, T; Hosomi, H; Iwamura, A; Nakajima, M; Yokoi, T	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Benachour, N; Vanderheyden, PML	1
Gust, R; Obexer, P; Salcher, S; Schoepf, AM	1
Foster, H; Foster, R; Philippou, H; Wilson, C	1
Bischoff-Kont, I; Fürst, R; Heering, J; Hernandez-Olmos, V; Kaps, A; Liu, T; Proschak, E; Rajkumar, R; Steinhilber, D	1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M	1
Morsing, P	1
Abrahamsson, T; Adler, G; Brandt-Eliasson, U; Karp, L; Morsing, P; Ohlson, K; Renberg, L; Sjöquist, PO	1
Kirk, JK	1
De Backer, JP; Fierens, FL; Vanderheyden, PM; Vauquelin, G	1
Kaplan, NM	1
Spence, JD	1
Benedict, C; Bunt, AM; Conlin, PR; Ribeiro, AB; Saito, I; Spence, JD; Williams, B	1
Casado, S; Farré, J; Gómez, J; Jiménez, A; López-Blaya, A; López-Farré, A; Montón, M; Núñez, A; Sánchez de Miguel, L; Zalba, LR	1
Kiukaanniemi, K; Pelkonen, O; Taavitsainen, P	1
Grossman, E; Messerli, FH; Neutel, JM	1
Howes, L; Wong, W	1
Fierens, FL; Vanderheyden, PM; Vauquelin, G	1
Badguet, JP; Mallion, JM	1
De Backer, JP; Fierens, FL; Morsing, P; Vanderheyden, PM; Vauquelin, G	1
Baican, M; Coltau, M; Domuta, G; Gilau, L; Hecht, A; Pasca, R; Puscas, I	1
Vidt, DG	1
Ramahi, TM	1
Brosnihan, KB; Diz, DI; Ferrario, CM; Fukuhara, M; Li, P; Neves, LA	1
Brunner, HR; Burnier, M; Centeno, C; Maillard, MP; Nussberger, J; Würzner, G	1
Belz, GG; Butzer, R; Kober, S; Mutschler, E	1
Rapi, J	1
Fakouhi, K; He, W; Krause, S; Krum, H; Nolly, H; Roniker, B; Workman, D	1
Brunner, HR; Burnier, M; Centeno, C; Maillard, MP; Perregaux, C; Stangier, J; Wienen, W	1
Bottari, S; De Backer, JP; Vanderheyden, PM; Vauquelin, G; Verheijen, I	1
Elmfeldt, D; Meredith, P; Olofsson, B	1
Alvarez, A; Fernández-Calotti, P; Gamberale, R; Geffner, JR; Giordano, M; Nahmod, KA; Nahmod, V; Raiden, S; Salamone, G; Vermeulen, ME	1
Mancini, GB	1
Alföldi, S	1
Terra, SG	1
Preobrazhenskiĭ, DV; Sidorenko, BA; Stetsenko, TM; Tarykina, EV; Tsurko, VV	1
Jermendy, G; Matos, L; Winkler, G	1
Dominiak, P; Häuser, W	1
Ivanova, NA; Preobrazhenskiĭ, DV; Sidorenko, BA; Soplevenko, AV; Stetsenko, TM	1
Ahn, JY; Ahn, TH; Chung, WJ; Han, SH; Jin, DK; Kang, WC; Kim, HS; Koh, KK; Park, GS; Shin, EK	1
Stumpe, KO	1
Dendorfer, A; Dominiak, P; Raasch, W; Tempel, K	1
Behlouli, H; Hudson, M; Humphries, K; Pilote, L; Sheppard, R; Tu, JV	1
Bramlage, CP; Bramlage, P; Paar, WD; Schmieder, RE; Thoenes, M	1
Belsey, JD	1
Huang, Z; Jansson, L; Sjöholm, A	1
Dal Pan, GJ; Governale, LA; Hammad, TA; McAdams, MA; Swartz, L	1
Hatzitolios, A; Ntaios, G; Savopoulos, C	1
Falvey, H; Lowy, A; Müller, E; Nixon, RM	1
Kamiyama, E; Mikkaichi, T; Nakai, D; Okazaki, O; Okudaira, N	1
Kumagai, K	1
Desai, AS; Givertz, MM; Shah, RV	1
Arsenault, J; Cabana, J; Escher, E; Guillemette, G; Lanthier, L; Lavigne, P; Leduc, R; Lehoux, J	1
Fang, JC; Oghlakian, GO; Sipahi, I	1
Aparasu, RR; Ashton, CM; Chen, H; Desai, RJ; Deswal, A; Johnson, ML; Mehta, HB; Morgan, RO	1
Joffe, MM; Yang, W	1
Ando, H; Fujimura, A; Hosohata, K; Saito, T; Ushijima, K	1
Spinar, J; Vítovec, J	1
Campbell, RT; Castagno, D; Hawkins, NM; Jhund, PS; McMurray, JJ; Petrie, MC	1
Inamdar, MN; Kulkarni, C; Kulkarni, KS; Moinuddin, G	1
Antoniou, T; Camacho, X; Gomes, T; Juurlink, DN; Mamdani, MM; Yao, Z	1
Ito, T; Kawahara, K; Kikuchi, K; Maruyama, I; Miura, N; Morimoto-Yamashita, Y; Murai, Y; Tanaka, E; Tancharoen, S	1
Caffrey, JL; Chang, CH; Lai, MS; Lin, JW; Wu, LC	1
Asner, R; Bayer, A; Kopf, W; Letzel, M; Schüssler, W; Sengl, M; Weiß, K	1
Carson, PE; Granger, CB; Jhund, PS; Kjekshus, J; Komajda, M; Kristensen, SL; Køber, L; McKelvie, RS; McMurray, JJ; Pfeffer, MA; Solomon, SD; Swedberg, K; Wedel, H; Wikstrand, J; Yusuf, S; Zile, MR	1
Rossignol, P; Zannad, F	1
Abdel Monem Hegazy, M; Fayez, YM	1
Bayer, A; Greco, G; Grosse, S; Heermann, A; Letzel, M; Letzel, T; Lucke, T; Schulz, W; Schüssler, W; Sengl, M	1
Andrenšek, S; Gričar, M	1
Asayama, K; Haga, T; Hosaka, M; Imai, Y; Inoue, R; Kikuya, M; Mano, N; Metoki, H; Murakami, T; Obara, T; Ohkubo, T; Satoh, M	1
Brolund, L; Brolund-Spaether, K; Cascorbi, I; Culman, J; Gohlke, P; Jacob, T; Schuster, SO; Zhao, Y	1
Agrawal, H; Albaghdadi, A; Bramblett, T; Mukherjee, D; Teleb, M	1
Jóźwiak, K; Kocki, T; Targowska-Duda, KM; Turski, WA; Wnorowski, A; Zakrocka, I	1
Im, DS; Kim, MJ	1
Anand, IS; Carson, PE; Desai, AS; Docherty, KF; Granger, CB; Jhund, PS; Komajda, M; McKelvie, RS; McMurray, JJV; Petrie, MC; Pfeffer, MA; Shen, L; Solomon, SD; Swedberg, K; Zile, MR	1
Hyoung Cho, J; Kim, H; Kim, HS; Lee, H; Lee, SH; Min Kim, T; Shin, J; Woo Yim, H; Yoon, KH	1
Briasouli, A; Briasoulis, A; Fujisaki, T; Kuno, T; Takagi, H; Ueyama, H	1
Anand, IS; Carson, P; Claggett, BL; Cunningham, JW; Desai, AS; Jhund, PS; John, JE; Kober, L; Lewis, EF; McMurray, JJV; Pfeffer, MA; Pitt, B; Shah, SJ; Solomon, SD; Swedberg, K; Vaduganathan, M; Yusuf, S; Zile, MR	1
Anand, IS; Carson, PE; Desai, AS; Granger, CB; Jhund, PS; Komajda, M; Køber, L; McKelvie, RS; McMurray, JJV; Pfeffer, MA; Shen, L; Solomon, SD; Swedberg, K; Zile, MR	1
Dantas, ASCL; de Lima, PC; de Souza, MN; Ferreira, LODS; Lima, MED; Maranho, RLDN; Monteiro, MA; Novotny, TS; Ochs, SM; Santana, DS	1
Bradley, M; Eworuke, E; Hedenmalm, K; Kurz, X; Lee, H; Quinten, C	1

Reviews

31 review(s) available for candesartan and avapro

Article	Year
Nonpeptide angiotensin II receptor antagonists: the next generation in antihypertensive therapy. Journal of medicinal chemistry, 1996, Feb-02, Volume: 39, Issue:3 Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Humans; Receptors, Angiotensin; Structure-Activity Relationship	1996
Angiotensin II AT1 receptor antagonists. Clinical implications of active metabolites. Journal of medicinal chemistry, 2003, Jun-05, Volume: 46, Issue:12 Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Growth Hormone; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Models, Molecular; Receptor, Angiotensin, Type 1; Tetrazoles; Thiophenes; Thromboxane A2	2003
Angiotensin II receptor type 1 (AT1) selective nonpeptidic antagonists--a perspective. Bioorganic & medicinal chemistry, 2010, Dec-15, Volume: 18, Issue:24 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Antihypertensive Agents; Humans; Losartan	2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Influence of the cellular environment on ligand binding kinetics at membrane-bound targets. Bioorganic & medicinal chemistry letters, 2017, 08-15, Volume: 27, Issue:16 Topics: Angiotensin II Type 1 Receptor Blockers; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Humans; Kinetics; Ligands; Protein Binding; Receptor, Angiotensin, Type 1; Receptors, Cell Surface; Signal Transduction	2017
Candesartan: a new-generation angiotensin II AT1 receptor blocker: pharmacology, antihypertensive efficacy, renal function, and renoprotection. Journal of the American Society of Nephrology : JASN, 1999, Volume: 10 Suppl 11 Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Disease Models, Animal; Hemodynamics; Humans; Hypertension; Irbesartan; Kidney; Losartan; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles	1999
Angiotensin-II receptor antagonists: their place in therapy. American family physician, 1999, Volume: 59, Issue:11 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Clinical Trials as Topic; Drug Administration Schedule; Drug Interactions; Heart Failure; Humans; Hypertension; Irbesartan; Losartan; Renin-Angiotensin System; Telmisartan; Tetrazoles; Valine; Valsartan	1999
Angiotensin II receptor antagonists in the treatment of hypertension. American family physician, 1999, Sep-15, Volume: 60, Issue:4 Topics: Algorithms; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Humans; Hypertension; Irbesartan; Losartan; Receptors, Angiotensin; Telmisartan; Tetrazoles; Valine; Valsartan	1999
Angiotensin II antagonists for hypertension: are there differences in efficacy? American journal of hypertension, 2000, Volume: 13, Issue:4 Pt 1 Topics: Angiotensin II; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Humans; Hypertension; Irbesartan; Losartan; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan	2000
Angiotensin II receptor blockers: equal or preferred substitutes for ACE inhibitors? Archives of internal medicine, 2000, Jul-10, Volume: 160, Issue:13 Topics: Acrylates; Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Drug Therapy, Combination; Heart; Humans; Hypertension; Imidazoles; Irbesartan; Kidney; Losartan; Renin-Angiotensin System; Telmisartan; Tetrazoles; Thiophenes	2000
Angiotensin receptor antagonists. Australian family physician, 2000, Volume: 29, Issue:7 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Humans; Hypertension; Irbesartan; Losartan; Telmisartan; Tetrazoles	2000
Putting the efficacy of candesartan cilexetil into perspective: a review of new comparative data. Journal of human hypertension, 2000, Volume: 14 Suppl 2 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cattle; Cerebellum; Circadian Rhythm; Female; Heart; Humans; Hypertension; In Vitro Techniques; Irbesartan; Kinetics; Losartan; Male; Middle Aged; Prodrugs; Rabbits; Randomized Controlled Trials as Topic; Receptors, Angiotensin; Renin; Tetrazoles; Time Factors	2000
Expanded role for ARBs in cardiovascular and renal disease? Recent observations have far-reaching implications. Postgraduate medicine, 2001, Volume: 109, Issue:4 Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biological Availability; Biphenyl Compounds; Cardiovascular Diseases; Humans; Imidazoles; Irbesartan; Kidney Diseases; Losartan; Metabolic Clearance Rate; Patient Selection; Renin-Angiotensin System; Telmisartan; Tetrazoles; Thiophenes; Treatment Outcome; Valine; Valsartan	2001
[Irbesartan: a new possibility in the treatment of hypertension]. Orvosi hetilap, 2002, May-26, Volume: 143, Issue:21 Topics: Acrylates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Atenolol; Benzimidazoles; Benzoates; Biological Availability; Biphenyl Compounds; Controlled Clinical Trials as Topic; Drug Administration Schedule; Enalapril; Half-Life; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan	2002
The relationships between dose and antihypertensive effect of four AT1-receptor blockers. Differences in potency and efficacy. Blood pressure, 2002, Volume: 11, Issue:5 Topics: Adult; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Irbesartan; Losartan; Male; Randomized Controlled Trials as Topic; Receptor, Angiotensin, Type 1; Tetrazoles; Treatment Outcome; Valine; Valsartan	2002
Emerging role of angiotensin II type 1 receptor blockers for the treatment of endothelial dysfunction and vascular inflammation. The Canadian journal of cardiology, 2002, Volume: 18, Issue:12 Topics: Acrylates; Aged; Antihypertensive Agents; Benzimidazoles; Biomarkers; Biphenyl Compounds; Coronary Artery Disease; Data Interpretation, Statistical; Diabetes Mellitus; E-Selectin; Endothelium, Vascular; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Tetrazoles; Thiophenes; Vasculitis	2002
[Diurnal blood pressure control in the optimal treatment of hypertension]. Orvosi hetilap, 2003, May-04, Volume: 144, Issue:18 Suppl 1 Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Circadian Rhythm; Humans; Hypertension; Irbesartan; Losartan; Telmisartan; Tetrazoles; Valine; Valsartan	2003
[Angiotensin I receptor antagonist losartan. Part II. Effects in arterial hypertension and diabetic nephropathy]. Kardiologiia, 2003, Volume: 43, Issue:2 Topics: Angiotensin I; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diastole; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Losartan; Meta-Analysis as Topic; Placebos; Prognosis; Randomized Controlled Trials as Topic; Sodium Chloride Symporter Inhibitors; Systole; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan	2003
[Theoretical background of angiotensin II receptor blockade and its features in clinical pharmacology]. Orvosi hetilap, 2003, Sep-07, Volume: 144, Issue:36 Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Humans; Imidazoles; Irbesartan; Losartan; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan	2003
[Candesartan - a novel AT(1)-angiotensin receptor blocker: peculiarities of pharmacology and experience of use in arterial hypertension]. Kardiologiia, 2004, Volume: 44, Issue:1 Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Diabetic Nephropathies; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Tetrazoles; Thiophenes; Valine; Valsartan	2004
Olmesartan compared with other angiotensin II receptor antagonists: head-to-head trials. Clinical therapeutics, 2004, Volume: 26 Suppl A Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Olmesartan Medoxomil; Randomized Controlled Trials as Topic; Tetrazoles; Treatment Outcome; Valine; Valsartan	2004
Valsartan vs. other angiotensin II receptor blockers in the treatment of hypertension: a meta-analytical approach. International journal of clinical practice, 2009, Volume: 63, Issue:5 Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Dose-Response Relationship, Drug; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Middle Aged; Prospective Studies; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan	2009
[Upstream approach for atrial fibrillation]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2010, Volume: 135, Issue:2 Topics: Amiodarone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Fibrillation; Benzimidazoles; Biphenyl Compounds; Drug Therapy, Combination; Humans; Irbesartan; Tetrazoles	2010
The effect of renin-angiotensin system inhibitors on mortality and heart failure hospitalization in patients with heart failure and preserved ejection fraction: a systematic review and meta-analysis. Journal of cardiac failure, 2010, Volume: 16, Issue:3 Topics: Age Factors; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Female; Heart Failure; Hospital Mortality; Hospitalization; Humans; Irbesartan; Male; Middle Aged; Prognosis; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Risk Factors; Sex Factors; Stroke Volume; Survival Analysis; Tetrazoles; Treatment Outcome	2010
Effects of telmisartan, irbesartan, valsartan, candesartan, and losartan on cancers in 15 trials enrolling 138,769 individuals. Journal of hypertension, 2011, Volume: 29, Issue:4 Topics: Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Benzoates; Biphenyl Compounds; Case-Control Studies; Double-Blind Method; Humans; Hypertension; Irbesartan; Losartan; Neoplasms; Randomized Controlled Trials as Topic; Telmisartan; Tetrazoles	2011
Treatment of heart failure with preserved ejection fraction: have we been pursuing the wrong paradigm? Mayo Clinic proceedings, 2011, Volume: 86, Issue:6 Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Cardiovascular Agents; Digitalis Glycosides; Exercise; Exercise Tolerance; Heart Failure; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertrophy, Left Ventricular; Irbesartan; Mineralocorticoid Receptor Antagonists; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Stroke Volume; Tetrazoles; Ventricular Dysfunction, Left; Verapamil	2011
[AII antagonists (candesartan and irbesartan) in the treatment of cardiovascular diseases]. Vnitrni lekarstvi, 2012, Volume: 58, Issue:10 Topics: Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cardiovascular Diseases; Humans; Irbesartan; Tetrazoles	2012
What have we learned about patients with heart failure and preserved ejection fraction from DIG-PEF, CHARM-preserved, and I-PRESERVE? Journal of the American College of Cardiology, 2012, Dec-11, Volume: 60, Issue:23 Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Cardiotonic Agents; Clinical Trials as Topic; Global Health; Heart Failure; Humans; Irbesartan; Stroke Volume; Survival Rate; Tetrazoles	2012
Potential of the angiotensin receptor blockers (ARBs) telmisartan, irbesartan, and candesartan for inhibiting the HMGB1/RAGE axis in prevention and acute treatment of stroke. International journal of molecular sciences, 2013, Sep-13, Volume: 14, Issue:9 Topics: Acute Disease; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Benzoates; Biphenyl Compounds; HMGB1 Protein; Humans; Hypertension; Irbesartan; Neurons; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Risk Factors; Stroke; Telmisartan; Tetrazoles	2013
Heart Failure with Preserved Ejection Fraction: Entresto a Possible Option. Cardiovascular & hematological disorders drug targets, 2017, Volume: 17, Issue:2 Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Clinical Trials as Topic; Drug Combinations; Heart; Heart Failure; Humans; Irbesartan; Perindopril; Tetrazoles; Valsartan	2017
Meta-Analysis Evaluating the Effects of Renin-Angiotensin-Aldosterone System Blockade on Outcomes of Heart Failure With Preserved Ejection Fraction. The American journal of cardiology, 2020, 04-15, Volume: 125, Issue:8 Topics: Aminobutyrates; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Cardiovascular Diseases; Drug Combinations; Heart Failure; Hospitalization; Humans; Irbesartan; Mineralocorticoid Receptor Antagonists; Mortality; Network Meta-Analysis; Perindopril; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Spironolactone; Stroke Volume; Tetrazoles; Treatment Outcome; Valsartan	2020

Trials

7 trial(s) available for candesartan and avapro

Article	Year
Comparative angiotensin II receptor blockade in healthy volunteers: the importance of dosing. Clinical pharmacology and therapeutics, 2002, Volume: 71, Issue:1 Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cross-Over Studies; Dose-Response Relationship, Drug; Humans; Irbesartan; Losartan; Male; Renin; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan	2002
Pharmacodynamic studies on the angiotensin II type 1 antagonists irbesartan and candesartan based on angiotensin II dose response in humans. Journal of cardiovascular pharmacology, 2002, Volume: 39, Issue:4 Topics: Adult; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Half-Life; Humans; Irbesartan; Male; Radioligand Assay; Receptor, Angiotensin, Type 1; Renin; Tetrazoles	2002
Efficacy of eplerenone added to renin-angiotensin blockade in hypertensive patients. Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:2 Topics: Abdominal Pain; Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Diarrhea; Double-Blind Method; Drug Therapy, Combination; Eplerenone; Female; Headache; Heart Rate; Humans; Hypertension; Irbesartan; Losartan; Male; Middle Aged; Patient Dropouts; Renin-Angiotensin System; Spironolactone; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan	2002
Comparison of effects of losartan, irbesartan, and candesartan on flow-mediated brachial artery dilation and on inflammatory and thrombolytic markers in patients with systemic hypertension. The American journal of cardiology, 2004, Jun-01, Volume: 93, Issue:11 Topics: Angiotensin II; Antihypertensive Agents; Benzimidazoles; Biomarkers; Biphenyl Compounds; Brachial Artery; Double-Blind Method; Female; Humans; Hypertension; Irbesartan; Losartan; Male; Middle Aged; Tetrazoles; Vasodilation	2004
Relationship between the receptor occupancy profile and pleiotropic effects of angiotensin II receptor blockers. British journal of clinical pharmacology, 2013, Volume: 75, Issue:2 Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Area Under Curve; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cross-Over Studies; Dinoprost; Double-Blind Method; Enzyme-Linked Immunosorbent Assay; Humans; Hypertension; Insulin; Insulin Resistance; Irbesartan; Luminescent Measurements; Male; Middle Aged; Oxidative Stress; Radioligand Assay; Receptors, Angiotensin; Tetrazoles; Time Factors; Valine; Valsartan; Young Adult	2013
International geographic variation in event rates in trials of heart failure with preserved and reduced ejection fraction. Circulation, 2015, Jan-06, Volume: 131, Issue:1 Topics: Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Canada; Europe; Female; Fluorobenzenes; Geography; Heart Failure; Hospitalization; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Irbesartan; Male; Middle Aged; Pyrimidines; Risk Factors; Rosuvastatin Calcium; Russia; Stroke Volume; Sulfonamides; Tetrazoles; Treatment Outcome; United States	2015
Myocardial Infarction in Heart Failure With Preserved Ejection Fraction: Pooled Analysis of 3 Clinical Trials. JACC. Heart failure, 2020, Volume: 8, Issue:8 Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Diuretics; Double-Blind Method; Female; Heart Failure; Humans; Irbesartan; Male; Morbidity; Myocardial Infarction; Risk Factors; Spironolactone; Stroke Volume; Systole; Tetrazoles	2020

Other Studies

54 other study(ies) available for candesartan and avapro

Article	Year
Distinction between surmountable and insurmountable selective AT1 receptor antagonists by use of CHO-K1 cells expressing human angiotensin II AT1 receptors. British journal of pharmacology, 1999, Volume: 126, Issue:4 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Cattle; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Humans; Inositol Phosphates; Receptors, Angiotensin; Recombinant Proteins; Tetrazoles; Transfection	1999
Pharmacophore, drug metabolism, and pharmacokinetics models on non-peptide AT1, AT2, and AT1/AT2 angiotensin II receptor antagonists. Journal of medicinal chemistry, 2005, Jun-30, Volume: 48, Issue:13 Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Binding Sites; Biphenyl Compounds; Kinetics; Losartan; Models, Molecular; Molecular Conformation; Oxidation-Reduction; Pharmaceutical Preparations; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Structure-Activity Relationship; Tetrazoles	2005
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
CYP2C9-mediated metabolic activation of losartan detected by a highly sensitive cell-based screening assay. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:5 Topics: Antihypertensive Agents; Aryl Hydrocarbon Hydroxylases; Benzbromarone; Biotransformation; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP2C9; Diclofenac; HEK293 Cells; Hep G2 Cells; Hepatocytes; Humans; Losartan; NF-E2-Related Factor 2; Semicarbazides; Sensitivity and Specificity; Time Factors; Uricosuric Agents	2011
Identification and development of non-cytotoxic cell death modulators: Impact of sartans and derivatives on PPARγ activation and on growth of imatinib-resistant chronic myelogenous leukemia cells. European journal of medicinal chemistry, 2020, Jun-01, Volume: 195 Topics: Animals; Cell Death; Cell Proliferation; Chlorocebus aethiops; COS Cells; Drug Design; Drug Resistance, Neoplasm; Humans; Imatinib Mesylate; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; PPAR gamma; Structure-Activity Relationship; Telmisartan	2020
Progress toward a Glycoprotein VI Modulator for the Treatment of Thrombosis. Journal of medicinal chemistry, 2020, 11-12, Volume: 63, Issue:21 Topics: Binding Sites; Biological Products; Humans; Ligands; Losartan; Molecular Dynamics Simulation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Protein Kinase Inhibitors; Signal Transduction; Small Molecule Libraries; Thrombosis	2020
Discovery of Irbesartan Derivatives as BLT2 Agonists by Virtual Screening. ACS medicinal chemistry letters, 2021, Aug-12, Volume: 12, Issue:8 Topics:	2021
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology. Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3 Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries	2023
Mechanistic differences of various AT1-receptor blockers in isolated vessels of different origin. Hypertension (Dallas, Tex. : 1979), 1999, Volume: 33, Issue:6 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blood Proteins; Female; Humans; Imidazoles; In Vitro Techniques; Irbesartan; Kinetics; Losartan; Male; Muscle Contraction; Muscle, Smooth, Vascular; Portal Vein; Rabbits; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles	1999
Insurmountable angiotensin AT1 receptor antagonists: the role of tight antagonist binding. European journal of pharmacology, 1999, May-14, Volume: 372, Issue:2 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Binding, Competitive; Biphenyl Compounds; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Humans; Imidazoles; Irbesartan; Losartan; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Recombinant Proteins; Tetrazoles	1999
Efficacy of angiotensin II antagonists in hypertension. The Canadian journal of cardiology, 1999, Volume: 15 Suppl F Topics: Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Diuretics; Drug Interactions; Drug Therapy, Combination; Humans; Hypertension; Irbesartan; Losartan; Randomized Controlled Trials as Topic; Tetrazoles; Treatment Outcome; Valine; Valsartan	1999
Comparative effects of angiotensin II AT-1-type receptor antagonists in vitro on human platelet activation. Journal of cardiovascular pharmacology, 2000, Volume: 35, Issue:6 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adult; Angiotensin II; Angiotensin Receptor Antagonists; Antibodies, Monoclonal; Benzimidazoles; Benzoates; Binding, Competitive; Biphenyl Compounds; Blood Platelets; Dose-Response Relationship, Drug; Humans; Imidazoles; Irbesartan; Losartan; Platelet Activation; Pyridines; Radioligand Assay; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Telmisartan; Tetrazoles; Thromboxane A2; Time Factors; Valine; Valsartan	2000
In vitro inhibition screening of human hepatic P450 enzymes by five angiotensin-II receptor antagonists. European journal of clinical pharmacology, 2000, Volume: 56, Issue:2 Topics: Acrylates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Imidazoles; In Vitro Techniques; Inhibitory Concentration 50; Irbesartan; Losartan; Microsomes, Liver; Protein Isoforms; Tetrazoles; Thiophenes; Valine; Valsartan	2000
Angiotensin II type 1 receptor antagonists. Why do some of them produce insurmountable inhibition? Biochemical pharmacology, 2000, Dec-01, Volume: 60, Issue:11 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Binding Sites; Biphenyl Compounds; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Humans; Irbesartan; Losartan; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Recombinant Proteins; Tetrazoles	2000
A two-state receptor model for the interaction between angiotensin II type 1 receptors and non-peptide antagonists. Biochemical pharmacology, 2001, Feb-01, Volume: 61, Issue:3 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; CHO Cells; Computer Simulation; Cricetinae; Dose-Response Relationship, Drug; Inositol Phosphates; Irbesartan; Kinetics; Losartan; Models, Biological; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles	2001
The mechanism of action of angiotensin II is dependent on direct activation of vascular smooth muscle carbonic anhydrase I. International journal of clinical & laboratory research, 2000, Volume: 30, Issue:3 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Carbonic Anhydrases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Erythrocytes; Female; Humans; In Vitro Techniques; Irbesartan; Male; Middle Aged; Muscle, Smooth, Vascular; Tetrazoles	2000
Can angiotensin II receptor blockers be used in patients who have developed a cough or angioedema as a result of taking an ACE inhibitor? Cleveland Clinic journal of medicine, 2001, Volume: 68, Issue:3 Topics: Acrylates; Angioedema; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Black or African American; Clinical Trials as Topic; Cough; Female; Humans; Imidazoles; Irbesartan; Losartan; Male; Randomized Controlled Trials as Topic; Sex Factors; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan	2001
The angiotensin II AT1 receptor antagonist irbesartan prevents thromboxane A2-induced vasoconstriction in the rat hind-limb vascular bed in vivo. Journal of hypertension, 2001, Volume: 19, Issue:3 Pt 2 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Vessels; Dose-Response Relationship, Drug; Hindlimb; Irbesartan; Male; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Thromboxane; Tetrazoles; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents	2001
In vitro and in vivo characterization of the activity of telmisartan: an insurmountable angiotensin II receptor antagonist. The Journal of pharmacology and experimental therapeutics, 2002, Volume: 302, Issue:3 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Cell Membrane; In Vitro Techniques; Irbesartan; Kinetics; Muscle, Smooth, Vascular; Radioligand Assay; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Telmisartan; Tetrazoles	2002
Antagonist interaction with endogenous AT(1) receptors in human cell lines. Biochemical pharmacology, 2002, Oct-15, Volume: 64, Issue:8 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Binding, Competitive; Biphenyl Compounds; Cell Line; CHO Cells; Cricetinae; Humans; Inositol Phosphates; Iodine Radioisotopes; Irbesartan; Muscle, Smooth, Vascular; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Tetrazoles; Transfection	2002
Control of dendritic cell differentiation by angiotensin II. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2003, Volume: 17, Issue:3 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antibodies; Benzimidazoles; Biphenyl Compounds; Cell Differentiation; Cells, Cultured; Dendritic Cells; Endocytosis; Hematopoietic Stem Cells; Humans; Irbesartan; Losartan; Lymphocyte Activation; Mice; Models, Biological; Monocytes; Phenotype; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles	2003
Cardiology patient page. Angiotensin receptor blockers. Circulation, 2003, Jun-24, Volume: 107, Issue:24 Topics: Acrylates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Diuretics; Dizziness; Drug Combinations; Drug Interactions; Heart Failure; Humans; Hypertension; Imidazoles; Irbesartan; Kidney Diseases; Losartan; Olmesartan Medoxomil; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan	2003
[Fast-acting sartan. High blood pressure therapy without long waiting time]. MMW Fortschritte der Medizin, 2003, Jun-12, Volume: 145, Issue:24 Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Olmesartan Medoxomil; Rats; Tetrazoles; Time Factors; Valine; Valsartan	2003
[Dosage equivalents of AT1-receptor antagonists available in Germany]. Deutsche medizinische Wochenschrift (1946), 2003, Oct-31, Volume: 128, Issue:44 Topics: Acrylates; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Clinical Trials as Topic; Germany; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Olmesartan Medoxomil; Placebos; Telmisartan; Tetrazoles; Therapeutic Equivalency; Thiophenes; Time Factors; Valine; Valsartan	2003
Peripheral sympatholytic actions of four AT1 antagonists: are they relevant for long-term antihypertensive efficacy? Journal of hypertension, 2005, Volume: 23, Issue:10 Topics: Acrylates; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Electric Stimulation; Imidazoles; Irbesartan; Losartan; Male; Norepinephrine; Rats; Rats, Inbred SHR; Sympathetic Fibers, Postganglionic; Sympatholytics; Tetrazoles; Thiophenes; Time Factors; Treatment Outcome	2005
Angiotensin II receptor blockers for the treatment of heart failure: a class effect? Pharmacotherapy, 2007, Volume: 27, Issue:4 Topics: Age Factors; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; British Columbia; Drug Prescriptions; Female; Heart Failure; Hospital Information Systems; Humans; Irbesartan; Losartan; Male; Ontario; Proportional Hazards Models; Quebec; Retrospective Studies; Survival Analysis; Survival Rate; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan	2007
[Albuminuria: an indicator of cardiovascular risk]. Medizinische Klinik (Munich, Germany : 1983), 2007, Oct-15, Volume: 102, Issue:10 Topics: Aged; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Anticholesteremic Agents; Antihypertensive Agents; Benzimidazoles; Biomarkers; Biphenyl Compounds; Capillary Permeability; Cardiovascular Diseases; Endothelium, Vascular; Female; Humans; Irbesartan; Membrane Potentials; Proteinuria; Risk Factors; Survival Rate; Tetrazoles	2007
Switch strategies in the management of hypertension: a cost minimisation analysis of angiotensin receptor blocker based regimen. Current medical research and opinion, 2008, Volume: 24, Issue:2 Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cost-Benefit Analysis; Drug Costs; Humans; Hypertension; Irbesartan; Losartan; Markov Chains; Tetrazoles; Valine; Valsartan	2008
Gender-specific regulation of pancreatic islet blood flow, insulin levels and glycaemia in spontaneously diabetic Goto-Kakizaki rats. Clinical science (London, England : 1979), 2008, Volume: 115, Issue:1 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Glucose; Captopril; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulin; Irbesartan; Islets of Langerhans; Male; Pravastatin; Rats; Rats, Mutant Strains; Regional Blood Flow; Sex Factors; Tetrazoles	2008
Identifying patterns of adverse event reporting for four members of the angiotensin II receptor blockers class of drugs: revisiting the Weber effect. Pharmacoepidemiology and drug safety, 2008, Volume: 17, Issue:9 Topics: Adverse Drug Reaction Reporting Systems; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Drug Approval; Humans; Irbesartan; Losartan; Tetrazoles; Time Factors; United States; Valine; Valsartan	2008
Telmisartan and carotid intima-media thickness regression: a class effect of angiotensin-receptor blockers? Hypertension research : official journal of the Japanese Society of Hypertension, 2008, Volume: 31, Issue:12 Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Biphenyl Compounds; Carotid Arteries; Humans; Irbesartan; Losartan; Telmisartan; Tetrazoles; Tunica Intima; Tunica Media; Valine; Valsartan	2008
Interaction of angiotensin II type 1 receptor blockers with P-gp substrates in Caco-2 cells and hMDR1-expressing membranes. Life sciences, 2010, Jan-02, Volume: 86, Issue:1-2 Topics: Adenosine Triphosphatases; Angiotensin II Type 1 Receptor Blockers; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; Benzoates; Biological Transport; Biphenyl Compounds; Caco-2 Cells; Calcium Channel Blockers; Cardiotonic Agents; Cell Membrane; Digoxin; Drug Interactions; Humans; Irbesartan; Losartan; Telmisartan; Tetrazoles; Verapamil	2010
A single-nucleotide polymorphism of alanine to threonine at position 163 of the human angiotensin II type 1 receptor impairs Losartan affinity. Pharmacogenetics and genomics, 2010, Volume: 20, Issue:6 Topics: Alanine; Angiotensin II; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Chlorocebus aethiops; COS Cells; Humans; Imidazoles; Inositol Phosphates; Irbesartan; Losartan; Polymorphism, Single Nucleotide; Receptor, Angiotensin, Type 1; Telmisartan; Tetrazoles; Threonine; Valine; Valsartan	2010
Comparative effectiveness of individual angiotensin receptor blockers on risk of mortality in patients with chronic heart failure. Pharmacoepidemiology and drug safety, 2012, Volume: 21, Issue:3 Topics: Aged; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Chronic Disease; Confounding Factors, Epidemiologic; Electronic Health Records; Female; Heart Failure; Hospitalization; Humans; Irbesartan; Losartan; Male; Models, Structural; Proportional Hazards Models; Retrospective Studies; Risk; Tetrazoles; Treatment Outcome; United States; Valine; Valsartan	2012
Subtle issues in model specification and estimation of marginal structural models. Pharmacoepidemiology and drug safety, 2012, Volume: 21, Issue:3 Topics: Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Female; Heart Failure; Humans; Irbesartan; Losartan; Male; Tetrazoles; Valine; Valsartan	2012
Modulation of haemodynamics, endogeneous antioxidant enzymes, and pathophysiological changes by selective inhibition of angiotensin II type 1 receptors in pressureoverload rats. Cardiovascular journal of Africa, 2013, Volume: 24, Issue:3 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cardiomegaly; Catalase; Disease Models, Animal; Hypertension; Irbesartan; Losartan; Male; Myocardium; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Superoxide Dismutase; Tetrazoles; Time Factors	2013
Comparative effectiveness of angiotensin-receptor blockers for preventing macrovascular disease in patients with diabetes: a population-based cohort study. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2013, Sep-03, Volume: 185, Issue:12 Topics: Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Benzimidazoles; Benzoates; Biphenyl Compounds; Diabetic Angiopathies; Dose-Response Relationship, Drug; Female; Heart Failure; Humans; Irbesartan; Losartan; Male; Myocardial Infarction; Proportional Hazards Models; Retrospective Studies; Stroke; Telmisartan; Tetrazoles; Treatment Outcome	2013
Examining the association of olmesartan and other angiotensin receptor blockers with overall and cause-specific mortality. Hypertension (Dallas, Tex. : 1979), 2014, Volume: 63, Issue:5 Topics: Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Cardiovascular Diseases; Cohort Studies; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Male; Middle Aged; Proportional Hazards Models; Registries; Retrospective Studies; Survival Rate; Taiwan; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan	2014
Behavior of sartans (antihypertensive drugs) in wastewater treatment plants, their occurrence and risk for the aquatic environment. Environmental science and pollution research international, 2014, Volume: 21, Issue:18 Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biodegradation, Environmental; Biphenyl Compounds; Chromatography, Liquid; Environmental Monitoring; Germany; Imidazoles; Irbesartan; Mass Spectrometry; Molecular Structure; Rivers; Tetrazoles; Thiophenes; Valine; Valsartan; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical	2014
Regional differences in heart failure with preserved ejection fraction trials: when nephrology meets cardiology but east does not meet west. Circulation, 2015, Jan-06, Volume: 131, Issue:1 Topics: Benzimidazoles; Biphenyl Compounds; Female; Fluorobenzenes; Geography; Heart Failure; Humans; Internationality; Irbesartan; Male; Mineralocorticoid Receptor Antagonists; Patients; Pyrimidines; Rosuvastatin Calcium; Spironolactone; Stroke Volume; Sulfonamides; Tetrazoles	2015
Mean centering of ratio spectra and concentration augmented classical least squares in a comparative approach for quantitation of spectrally overlapped bands of antihypertensives in formulations. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2015, Apr-05, Volume: 140 Topics: Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Hydrochlorothiazide; Irbesartan; Least-Squares Analysis; Spectrophotometry; Tablets; Tetrazoles	2015
LC-MS screening techniques for wastewater analysis and analytical data handling strategies: Sartans and their transformation products as an example. Chemosphere, 2015, Volume: 137 Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Chromatography, Liquid; Environmental Monitoring; Imidazoles; Irbesartan; Laboratories; Mass Spectrometry; Tetrazoles; Wastewater; Water Pollutants, Chemical; Water Purification; Workflow	2015
Determination of azide impurity in sartans using reversed-phase HPLC with UV detection. Journal of pharmaceutical and biomedical analysis, 2016, Jun-05, Volume: 125 Topics: Azides; Benzimidazoles; Biphenyl Compounds; Chromatography, High Pressure Liquid; Irbesartan; Limit of Detection; Reference Standards; Reproducibility of Results; Spectrophotometry, Ultraviolet; Tetrazoles; Valsartan	2016
The velocity of antihypertensive effects of seven angiotensin II receptor blockers determined by home blood pressure measurements. Journal of hypertension, 2016, Volume: 34, Issue:6 Topics: Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Blood Pressure Determination; Female; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Male; Middle Aged; Oxadiazoles; Self Care; Telmisartan; Tetrazoles; Time Factors; Valsartan	2016
Neuroprotective effects of AT1 receptor antagonists after experimental ischemic stroke: what is important? Naunyn-Schmiedeberg's archives of pharmacology, 2017, Volume: 390, Issue:9 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blood-Brain Barrier; Brain Ischemia; Disease Models, Animal; Dose-Response Relationship, Drug; Irbesartan; Losartan; Male; Neuroprotective Agents; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Stroke; Tetrazoles; Tissue Distribution	2017
Angiotensin II type 1 receptor blockers decrease kynurenic acid production in rat kidney in vitro. Naunyn-Schmiedeberg's archives of pharmacology, 2019, Volume: 392, Issue:2 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Humans; Imidazoles; Irbesartan; Kidney; Kynurenic Acid; Losartan; Male; Rats, Wistar; Telmisartan; Tetrazoles; Transaminases; Valsartan	2019
Suppressive effects of type I angiotensin receptor antagonists, candesartan and irbesartan on allergic asthma. European journal of pharmacology, 2019, Jun-05, Volume: 852 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Allergic Agents; Asthma; Benzimidazoles; Biphenyl Compounds; Bronchoalveolar Lavage Fluid; Cytokines; Eosinophils; Female; Irbesartan; Lung; Mast Cells; Mice; Mucins; Receptor, Angiotensin, Type 1; Tetrazoles; Th2 Cells	2019
Prior Pacemaker Implantation and Clinical Outcomes in Patients With Heart Failure and Preserved Ejection Fraction. JACC. Heart failure, 2019, Volume: 7, Issue:5 Topics: Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Cardiac Pacing, Artificial; Cardiovascular Diseases; Cause of Death; Death, Sudden, Cardiac; Female; Heart Failure; Hospitalization; Humans; Irbesartan; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Mortality; Pacemaker, Artificial; Prognosis; Proportional Hazards Models; Randomized Controlled Trials as Topic; Spironolactone; Stroke Volume; Tetrazoles; Ventricular Dysfunction, Left	2019
The short-term effects of angiotensin II receptor blockers on albuminuria and renal function in Korean patients. Basic & clinical pharmacology & toxicology, 2020, Volume: 126, Issue:5 Topics: Albuminuria; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Cohort Studies; Female; Humans; Irbesartan; Kidney; Male; Middle Aged; Republic of Korea; Retrospective Studies; Tetrazoles	2020
Developing and validating models to predict sudden death and pump failure death in patients with heart failure and preserved ejection fraction. Clinical research in cardiology : official journal of the German Cardiac Society, 2021, Volume: 110, Issue:8 Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biomarkers; Biphenyl Compounds; Death, Sudden, Cardiac; Defibrillators, Implantable; Electrocardiography; Female; Heart Failure; Humans; Irbesartan; Male; Mineralocorticoid Receptor Antagonists; Natriuretic Peptide, Brain; Peptide Fragments; Predictive Value of Tests; Randomized Controlled Trials as Topic; Risk Assessment; Sex Factors; Stroke Volume; Tetrazoles	2021
Investigation of Carcinogenic Impurities of N-Nitrosamines in Sartan Pharmaceutical Products Marketed in Brazil: Development and Validation of Method Based on High-Performance Liquid Chromatography-Tandem Mass Spectrometry. Journal of pharmaceutical sciences, 2023, Volume: 112, Issue:5 Topics: Angiotensin II Type 1 Receptor Blockers; Brazil; Carcinogens; Chromatography, High Pressure Liquid; Humans; Irbesartan; Losartan; Nitrosamines; Pharmaceutical Preparations; Tandem Mass Spectrometry; Telmisartan; Valsartan	2023
A collaborative study of the impact of N-nitrosamines presence and ARB recall on ARB utilization - results from IQVIA™ Disease Analyzer Germany. European journal of clinical pharmacology, 2023, Volume: 79, Issue:6 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Germany; Humans; Hypertension; Irbesartan; Losartan; Nitrosamines; Valsartan	2023