Compounds > candesartan

candesartan and angiotensin ii

candesartan has been researched along with angiotensin ii in 416 studies

Research

Studies (416)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's95 (22.84)18.2507
2000's233 (56.01)29.6817
2010's80 (19.23)24.3611
2020's8 (1.92)2.80

Authors

AuthorsStudies
De Backer, JP; Fierens, FL; Fraeyman, N; Vanderheyden, PM; Vauquelin, G1
Åqvist, J; Gutiérrez-de-Terán, H; Hallberg, A; Sallander, J; Wallinder, C1
Bernhardt, G; Biselli, S; Buschauer, A; Cabrele, C; Einsiedel, J; Gmeiner, P; Hübner, H; Keller, M; Kuhn, KK; Mollereau, C; Svobodová, J; Vanderheyden, PM; Wifling, D1
Li, XC; Widdop, RE2
Fukuo, K; Inoue, T; Jiang, B; Koh, E; Morimoto, S; Nabata, T; Ogihara, T; Rakugi, H; Tomita, J1
Kawahara, Y; Nakayama, I; Okuda, M; Tsuda, T; Yokoyama, M1
Kadowaki, T; Katoh, Y; Komuro, I; Nagai, R; Tobe, K; Yamazaki, T; Yazaki, Y1
Ando, A; Fujibayashi, M; Fujiwara, Y; Imai, E; Kamada, T; Kaneko, T; Moriyama, T; Ueda, N; Xia, C1
Paulson, OB; Strandgaard, S; Vraamark, T; Waldemar, G1
Hiroi, Y; Komuro, I; Kudoh, S; Mizuno, T; Shiojima, I; Takano, H; Tobe, K; Ueki, K; Yamazaki, T; Zou, Y1
Düsing, R; Feltkamp, H; Flesch, M; Ko, Y; Sachinidis, A; Seul, C; Vetter, H1
Hoshijima, M; Kawahara, Y; Nakayama, I; Okuda, M; Yokoyama, M1
Gross, V; Lippoldt, A; Luft, FC; Schneider, W1
Baba, A; Hano, T; Mizukoshi, M; Nakamura, N; Nishio, I1
Higaki, J; Higashimori, K; Mikami, H; Ogihara, T; Rakugi, H; Shi, SJ1
Abe, Y; Aki, Y; He, H; Kimura, S; Kita, T; Tamaki, T; Tomohiro, A1
Eguchi, S; Hirata, Y; Kanno, K; Kano, H1
Habuchi, Y; Lu, LL; Morikawa, J; Yoshimura, M1
Inada, Y; Nishikawa, K; Noda, M; Ojima, M; Sanada, T; Shibouta, Y; Wada, T1
Inada, Y; Kohara, Y; Kubo, K; Naka, T; Nishikawa, K; Noda, M; Ojima, M; Sanada, T; Shibouta, Y; Wada, T2
Fukiyama, K; Matayoshi, R; Muratani, H; Sesoko, S; Takishita, S; Teruya, H1
Akimoto, Y; Aoki, H; Hirano, H; Karube, M; Koyama, N; Nagai, A; Nakamura, Y; Oda, T; Yoshimura, Y1
Hashimoto, S; Kawata, T; Koike, T1
Fukuda, N; Izumi, Y; Kanmatsuse, K; Kubo, A; Soma, M1
Düsing, R; el-Haschimi, K; Ko, Y; Sachinidis, A; Seul, C; Vetter, H1
Fujimoto, M; Hara, M; Itazaki, K; Itoh, N1
el-Haschimi, K; Epping, P; Ko, Y; Sachinidis, A; Seul, C; Vetter, H1
Hazon, N; Takei, Y; Tierney, M1
Inada, Y; Kubo, K; Nishikawa, K; Ojima, M; Sanada, T; Shibouta, Y; Wada, T1
Ito, M; Iwao, T; Nakagawa, M; Saikawa, T; Sakata, T; Takakura, T; Yasunaga, S; Yonemochi, H1
Inada, Y; Kanehara, H; Kurobe, Y; Miyazaki, M; Nishikawa, K; Song, K; Wada, T1
Aikawa, J; Fukazawa, M; Ishikawa, M; Moroi, M; Namiki, A; Yamaguchi, T1
Fukamizu, A; Hibi, K; Ishigami, T; Ishii, M; Kihara, M; Mizuno, K; Murakami, K; Nyui, N; Ochiai, H; Ohno, S; Tamura, K; Umemura, S; Yabana, M1
Miura, T; Nakano, A; Shimamoto, K; Suzuki, K; Ura, N1
Champion, HC; Kadowitz, PJ1
Abe, I; Fujii, K; Fujishima, M; Onaka, U1
Abe, K; Abe, M; Arima, S; Endo, Y; Ito, S; Ogawa, S; Omata, K; Takeuchi, K; Tsunoda, K; Yaoita, H1
Abe, K; Arima, S; Endo, Y; Ito, S; Omata, K; Takeuchi, K; Tsunoda, K; Yaoita, H1
Jin, D; Miyazaki, M; Oka, Y; Shiota, N; Song, K; Takai, S1
Higaki, J; Mikami, H; Moriguchi, A; Ogihara, T; Zhu, DN1
Champion, HC; Czapla, MA; Kadowitz, PJ1
Chen, X; Fogo, A; Ichikawa, I; Inagami, T; Matsusaka, T; Niimura, F; Nishimura, H; Okubo, S; Tsuchida, S; Utsunomiya, H1
Fukuda, K; Hori, S; Kodama, H; Makino, S; Ogawa, S; Pan, J; Sano, M; Takahashi, T1
Aikawa, R; Komuro, I; Kudoh, S; Nagai, R; Uozumi, H; Yamazaki, T; Yazaki, Y; Zou, Y1
Hamanaka, I; Harada, M; Ishikawa, M; Itoh, H; Kajiyama, N; Kamitani, S; Kuwahara, K; Masuda, I; Miyamoto, Y; Nakagawa, O; Nakao, K; Ogawa, E; Saito, Y; Takahashi, N1
Belz, GG; Breithaupt-Grögler, K; Butzer, R; Fuchs, B; Herrmann, V; Högemann, A; Magin, SG; Malerczyk, C; Mutschler, E; Roll, S; Voith, B1
Hibi, K; Ishigami, T; Ishii, M; Kihara, M; Nyui, N; Tamura, K; Toya, Y; Umemura, S1
Brilla, CG; Rupp, H; Scheer, C1
Baltatu, O; Buikema, H; Ganten, D; Nishimura, H; Urata, H1
Fujimura, A; Gotoh, E; Ishii, M; Iwamoto, T; Shionoiri, H; Sugimoto, K; Takasaki, I; Takizawa, T; Tokita, Y1
Abe, I; Fujishima, M; Kagiyama, S; Liu, Y; Matsumura, K; Tsuchihashi, T1
Nanbu, A; Nishimura, M; Ohtsuka, K; Sakamoto, M; Takahashi, H; Yoshimura, M1
Dendorfer, A; Dominiak, P; Raasch, W; Tempel, K2
Arai, K; Demura, H; Imaki, T; Kobayashi, M; Miyazaki, H; Naruse, K; Naruse, M; Seki, T; Tanabe, A; Yoshimoto, T1
Fujio, Y; Kishimoto, T; Kunisada, K; Matsui, H; Negoro, S; Oh, H; Tone, E; Yamauchi-Takihara, K1
De Backer, JP; Fierens, FL; Vanderheyden, PM; Vauquelin, G2
Ardaillou, R1
Ardaillou, R; Chansel, D; Chatziantoniou, C; Dussaule, JC1
Arendshorst, WJ; Iversen, BM1
Bivalacqua, TJ; Champion, HC; Kadowitz, PJ; Lambert, DG; McNamara, DB2
Bivalacqua, TJ; Champion, HC; Dalal, A; Kadowitz, PJ; Lambert, DG1
Cervenka, L; Navar, LG1
Arendshorst, WJ; Coffman, TM; Oliverio, MI; Purdy, KE; Ruan, X1
Demeilliers, B; Jover, B; Mimran, A1
Goligorsky, MS; Kornfeld, M; Moore, LC; Thorup, C1
Bell, PD; Peti-Peterdi, J1
Cervenka, L; Mitchell, KD; Navar, LG; Wang, CT1
Higaki, J; Moriguchi, K; Ogihara, T; Ohishi, M; Okamura, A; Rakugi, H; Suzuki, K; Takiuchi, S; Yanagitani, Y1
Akashi, K; Asayama, J; Kawahara, A; Keira, N; Kobara, M; Matoba, S; Nakagawa, M; Tatsumi, T1
Kawachi, H; Kimura, H; Nakamura, T; Obata, J; Ohno, S; Shimizu, F; Yoshida, Y1
Inada, M; Iwasaka, T; Maruyama, K; Masaki, H; Matsubara, H; Mori, Y; Moriguchi, Y; Murasawa, S; Sakamoto, K; Shibasaki, Y; Tanaka, Y; Tsutumi, Y1
Arendshorst, WJ; Brännström, K1
Yamazaki, T; Yazaki, Y1
De Backer, JP; Fierens, F; Vanderheyden, PM; Vauquelin, G1
Buter, H; de Jong, PE; de Zeeuw, D; Navis, GY; Woittiez, AJ1
Fujita, T; Ishigami, T; Iwamoto, T; Kihara, M; Kobayashi, S; Toya, Y; Umemura, S; Yabana, M1
Cervenka, L; Harrison-Bernard, LM; Imig, JD; Mitchell, KD; Navar, LG; Wang, CT1
Sharma, A; Singh, M1
Fukuda, N; Hu, WY; Izumi, Y; Kanmatsuse, K; Kishioka, H; Kubo, A; Satoh, C; Soma, M; Watanabe, Y1
Abrahamsson, T; Adler, G; Brandt-Eliasson, U; Karp, L; Morsing, P; Ohlson, K; Renberg, L; Sjöquist, PO1
Nishimura, Y; Saavedra, JM1
Kirk, JK1
Rydén, L; Shimizu, M; Sjöquist, PO; Wang, QD1
Garcha, RS; Hughes, AD; Sever, PS2
Inoue, K; Kawamura, K; Kubota, J; Nishimura, H1
Grohé, C; Löbbert, K; Stimpel, M; van Eickels, M; Vetter, H1
Kaplan, NM1
Sjöquist, PO; Wang, QD1
Imaizumi, A; Johns, EJ; Kohsaka, T; Nakamura, A; Yanagawa, Y1
Bivalacqua, TJ; Champion, HC; Dalal, A; Kadowitz, PJ1
van Veldhuisen, DJ; Voors, AA1
Ardaillou, R; Chansel, D; Llorens-Cortes, C; Vandermeersch, S1
Ichimori, Y; Noda, M; Tani, A1
Benedict, C; Bunt, AM; Conlin, PR; Ribeiro, AB; Saito, I; Spence, JD; Williams, B1
Ishii, K; Isobe, K; Kawakami, Y; Nakai, T; Nanmoku, T; Takekoshi, K1
Casado, S; Farré, J; Gómez, J; Jiménez, A; López-Blaya, A; López-Farré, A; Montón, M; Núñez, A; Sánchez de Miguel, L; Zalba, LR1
Arakawa, K; Gondo, N; Ideishi, M; Kumagai, K; Nakashima, H; Urata, H1
Howes, L; Wong, W1
El Dahr, SS; Majid, DS; Navar, LG; Omoro, SA1
Meredith, PA1
Inada, Y; Nishikawa, K; Ojima, M; Sanada, T; Shibouta, Y; Wada, T1
Chatziantoniou, C; Dussaule, JC; Fakhouri, F; Tharaux, PL1
Guo, DF; Inagami, T; Kimura, H; Naito, A; Nakamura, T; Obata, J; Shimizu, F; Takano, H; Yoshida, Y1
Bader, M; Baltatu, O; Caligiorne, SM; Campagnole-Santos, MJ; Fontes, MA; Ganten, D; Santos, RA1
Ito, T; Nishimura, Y; Saavedra, JM1
Bouchie, JL; Chen, HC; Clermont, AC; Feener, EP; Hampe, J; Izumo, S; Perez, AS1
Fukuda, N; Kanmatsuse, K; Kishioka, H; Kubo, A; Nakayama, M; Satoh, C; Teng, J1
Aneman, A; Ewert, S; Fändriks, L; Laesser, M; Pettersson, A1
Fierens, FL; Vanderheyden, PM; Vauquelin, G1
Badguet, JP; Mallion, JM1
Eto, T; Imamura, T; Kato, J; Kitamura, K; Koiwaya, Y; Matsuo, T; Onitsuka, H; Tsumori, Y; Yamakawa, H1
Bader, M; Böhm, M; Bricca, G; Ganten, D; Monti, J; Schinke, M1
Beppu, S; Ishikura, F; Kobayashi, H; Omura, T; Takeuchi, K; Yoshikawa, J; Yoshiyama, M1
De Backer, JP; Fierens, FL; Morsing, P; Vanderheyden, PM; Vauquelin, G1
Cerra, MC; Hazon, N; Takei, Y; Tierney, ML; Tota, B1
Baican, M; Coltau, M; Domuta, G; Gilau, L; Hecht, A; Pasca, R; Puscas, I1
Bader, M; Baltatu, O; Caligiorni, S; Campagnole-Santos, MJ; Fontes, MA; Ganten, D; Santos, RA1
Ardaillou, R; Chansel, D; Curat, C; Oko, A; Vandermeersch, S1
Vidt, DG1
Ramahi, TM1
De Backer, J; Fierensa, FL; Roggeman, C; Thekkumkara, TJ; Vanderheyden, PM; Vauquelin, G1
Ishibashi, T; Maruyama, Y; Nagata, K; Nakazato, K; Ohkawara, H; Sakamoto, T; Seino, Y; Teramoto, T; Yokoyama, K1
Eshima, K; Hirooka, Y; Shigematsu, H; Shihara, M; Tagawa, T; Takeshita, A1
Hauner, H; Lee, YM; Skurk, T1
Derebail, VK; Pollock, DM; Pollock, JS; Yamamoto, T1
Fujita, M; Fukai, M; Furukawa, H; Horiuchi, H; Ishikawa, H; Jin, MB; Magata, S; Masuko, H; Nagashima, K; Ogata, K; Shimamura, T; Suzuki, T; Taniguchi, M; Todo, S1
Berlowitz, MS; Colombo, PC; Ennezat, PV; Hankins, SR; Latif, F; Le Jemtel, TH; Moskowitz, R; Tandon, S1
Benedict, CR; Katagiri, T; Pakala, R; Watanabe, T1
McMurray, JJ1
Ishii, K; Isobe, K; Kawakami, Y; Nakai, T; Takekoshi, K1
Cervenka, L; Heller, J; Kramer, HJ; Malý, J1
Fukui, H; Ikenaka, Y; Kuriyama, S; Nakatani, T; Noguchi, R; Tsujinoue, H; Yoshii, J; Yoshiji, H1
Emoto, N; Fukuya, H; Ikeda, K; Nonaka, H; Okamura, H; Raharjo, SB; Rohman, MS; Yagita, K; Yokoyama, M1
Dechow, C; Haxsen, V; Lehrke, I; Morath, C; Peters, J; Ritz, E; Wagner, J; Waldherr, R1
Ishii, K; Isobe, K; Kawakami, Y; Nakai, T; Shibuya, S; Takekoshi, K2
Balt, JC; Mathy, MJ; Pfaffendorf, M; van Zwieten, PA1
Bell, PD; Kovács, G; Peti-Peterdi, J; Rosivall, L1
Fukuuchi, Y; Inoue, K; Kobari, M; Otomo, M; Takao, M; Tanahashi, N; Tomita, M; Tomita, Y; Yokoyama, M1
Benes, E; Hammond, TG; Imig, JD; Navar, LG; Orengo, S; Zhuo, JL1
Bartels, T; Dendorfer, A; Dominiak, P; Gieselberg, A; Raasch, W1
Hautala, N; Ruskoaho, H; Szokodi, I; Tenhunen, O1
Brunner, HR; Burnier, M; Centeno, C; Maillard, MP; Nussberger, J; Würzner, G1
Fisher, ND; Hollenberg, NK; Lansang, MC; Osei, SY; Price, DA1
Lippert, C; Mueck, AO; Seeger, H; Wallwiener, D1
Howes, L; Phoon, S; Tran, D1
Andersen, JL; Bie, P; Sandgaard, NC1
Belz, GG; Butzer, R; Kober, S; Mutschler, E1
Thurston, H1
Andersen, JL; Bie, P; Holstein-Rathlou, NH; Sandgaard, NC1
Bell, PD; Peti-Peterdi, J; Warnock, DG1
Honda, T; Kobayashi, N; Kobayashi, T; Matsuoka, H; Mita, S; Nakano, S; Tsubokou, Y1
Endoh, M; Ichiyanagi, O; Ishii, K1
Howes, LG; Phoon, S1
Fujii, S; Kato, S; Kubota, I; Miyamoto, T; Miyashita, T; Takahashi, H; Takeishi, Y; Tomoike, H; Yoshimura, T1
Durie, M; Levy, BI; Silvestre, JS; Tamarat, R1
Culman, J; Gohlke, P; Jürgensen, T; Kox, T; Rascher, W; Unger, T; von Kügelgen, S1
Balt, JC; Mathy, MJ; Nap, A; Pfaffendorf, M; van Zwieten, PA1
Bergström, G; Jia, J; Johansson, M; Lambert, G; Nyström, HC1
Böhm, M; Hilgers, S; Laufs, U; Nickenig, G; Wassmann, S1
Imuro, Y; Iwasaka, T; Izuoka, T; Kitashiro, S; Mimura, J; Miyoshi, H; Saito, D; Takayama, Y; Tokioka, M; Yamamoto, S1
He, G; Jing, T; Liu, J; Wang, G; Wang, H; Wu, H1
Ichihara, S; Iwase, M; Izawa, H; Nagasaka, T; Nagata, K; Nakashima, N; Obata, K; Odashima, M; Somura, F; Yamada, Y; Yokota, M1
Brunner, HR; Burnier, M; Centeno, C; Maillard, MP; Perregaux, C; Stangier, J; Wienen, W1
Bottari, S; De Backer, JP; Vanderheyden, PM; Vauquelin, G; Verheijen, I1
Hattori, Y; Jesmin, S; Kitabatake, A; Mowa, CN; Sakuma, I1
Andersson, OK; Elmfeldt, D; Friberg, PR; Fridman, KU; Wysocki, M1
Imai, M; Kawai, A; Kumagai, H; Matsuura, T; Onimaru, H; Oshima, N; Sakata, K; Saruta, T1
Holtz, J; Morawietz, H; Quinn, MT; Rueckschloss, U1
Coffman, TM; Cook, AK; Harrison-Bernard, LM; Oliverio, MI1
Edvinsson, L; Malmsjö, M; Pantev, E; Stenman, E; Wackenfors, A1
Fujimura, M; Hashimoto, T; Ishiura, Y; Kamio, Y; Kita, T; Myou, S; Nakao, S; Watanabe, K1
Bovim, G; Helde, G; Sand, T; Stovner, LJ; Tronvik, E1
deChâtel, R; Ilves, M; Kinnunen, P; Piuhola, J; Ruskoaho, H; Szokodi, I; Vuolteenaho, O1
Alvarez, A; Fernández-Calotti, P; Gamberale, R; Geffner, JR; Giordano, M; Nahmod, KA; Nahmod, V; Raiden, S; Salamone, G; Vermeulen, ME1
Chiba, S; Inada, Y; Nakane, T1
DiBona, GF1
Aslam, S; Blau, J; Chabrashvili, T; Karber, A; Kitiyakara, C; Welch, WJ; Wilcox, CS1
Matsuoka, S; Nagaoka, M; Okamoto, H; Shimazu, E; Takano, M; Yayama, K1
Itoh, T; Kajikuri, J; Mabuchi, Y; Suzuki, Y; Tada, T1
Boonstra, PW; Buikema, H; Lübeck, RH; van Buiten, A; van Gilst, WH; van Veldhuisen, DJ; Voors, AA; Wagenaar, LJ1
Head, GA; Mayorov, DN1
Ageloff, S; Beutler, KT; Brooks, HL; Fenton, RA; Knepper, MA; Masilamani, S; Nielsen, J; Packer, RK; Turban, S1
Ando, H; Armando, I; Baiardi, G; Bregonzio, C; Jezova, M; Saavedra, JM1
Nielsen, LR1
Boulanger, CM; Ebrahimian, T; Mathieu, E; Silvestre, JS1
Kinugawa, K; Nagai, R; Takahashi, T1
Alesse, E; Bravi, MC; Croce, G; Desideri, G; Ferri, C; Marinucci, MC; Santucci, A; Tucci, M1
Schieffer, B; Schmidt, B1
Cachofeiro, V; Cediel, E; de las Heras, N; González Pacheco, FR; Jiménez, J; Lahera, V; Oubina, MP; Sanz-Rosa, D; Vegazo, O1
Jandhyala, BS; Tallam, LS1
Fine, LG; Norman, JT; Singer, M; Stidwill, R1
DiBona, GF; Jones, SY1
Buikema, H; de Zeeuw, D; Gschwend, S; Henning, RH; Pinto, YM; van Gilst, WH1
Schiffrin, EL; Touyz, RM1
Adam, AG; Jaimes, EA; Raij, L; Zhou, MS1
Endoh, S; Hayashi, T; Kitaura, Y; Mori, T; Okabe, M; Shimomura, H; Sohmiya, K; Terasaki, F; Ukimura, A1
Navar, LG; Nishiyama, A; Seth, DM1
Dominiak, P; Häuser, W1
Abe, Y; Kimura, S; Nishiyama, A; Rahman, M; Shokoji, T; Zhang, GX1
Brunner, HR; Burnier, M; Chiclero, A; Chioléro, A; Maillard, M; Nussberger, J; Wuerzner, G1
Amiri, F; Banes, AK; Jenkins, J; Marrero, MB; Pollock, DM; Redd, H; Shaw, S1
Imaizumi, T; Kai, H; Koga, M; Kudo, H; Kuwahara, F; Tahara, N; Takemiya, K; Tokuda, K; Yamamoto, T; Yasukawa, H1
Cuspidi, C; Leonetti, G; Zanchetti, A1
Imaizumi, T; Kai, H; Kuwahara, F; Tokuda, K1
Edvinsson, L; Stenman, E1
Backer, JP; Tourlousse, D; Vanderheyden, PM; Vauquelin, G; Verheijen, I1
Anzai, T; Hashimoto, K; Himeno, H; Imai, K; Kawana, M; Kitakaze, M; Koretsune, Y; Maruyama, S; Masaoka, Y; Matsubara, H; Matsuoka, T; Miyao, Y; Miyatake, K; Miyauchi, T; Nakamura, Y; Nomura, F; Okamoto, H; Ozono, K; Sekiya, M; Shinohara, H; Shintani, U; Shiraki, T; Takaoka, H; Tsutamoto, T; Yasumura, Y; Yokoya, K; Yokoyama, H1
Critchley, J; Critchley, L; Ding, B; Fok, B; James, A; Thomas, GN; Tomlinson, B; Wang, D1
Agarwal, A; Fisher, ND; Hollenberg, NK; Laffel, LM; Lansang, MC; Price, DA; Stevanovic, R; Williams, GH1
Hara, Y; Imaki, T; Naruse, M; Nishikawa, T; Sato, A; Takano, K; Tanabe, A; Tsuchiya, K1
Lochard, N; Reudelhuber, TL; Silversides, DW; Thibault, G; Touyz, RM1
Bäcker, A; Bader, M; Cervenka, L; Ganten, D; Husková, Z; Kopkan, L; Kramer, HJ; Vanourková, Z1
Hauner, H; Skurk, T; van Harmelen, V1
Akazawa, H; Fujita, T; Fukamizu, A; Iiri, T; Iwanaga, K; Kihara, M; Komuro, I; Kudoh, S; Makita, N; Minamino, T; Nagai, T; Qin, Y; Sano, M; Takano, H; Tamura, K; Toko, H; Umemura, S; Zhu, W; Zou, Y1
Ahn, JY; Ahn, TH; Chung, WJ; Han, SH; Jin, DK; Kang, WC; Kim, HS; Koh, KK; Park, GS; Shin, EK1
Iigaya, K; Kumagai, H; Onami, T; Saruta, T; Takimoto, C1
Hayashi, K; Iwamoto, K; Kizawa, Y; Koike, K; Kusama, T; Murakami, H; Ohsawa, M; Ohuchi, N; Sano, M; Taniguchi, Y1
Ando, H; Jezova, M; Saavedra, JM; Zhou, J1
Harada, S; Kido, H; Morimoto, S; Nakagawa, M; Oguni, A; Sasaki, S; Takeda, K1
Harris, PJ; Hiranyachattada, S1
Ebinger, G; Fournié-Zaluski, MC; Michotte, Y; Sarre, S; Stragier, B; Vanderheyden, P; Vauquelin, G1
Bergmann, P; Biarent, D; Hubloue, I; Kerbaul, F; Leeman, M; Milani, GM; Naeije, R; Rondelet, B; Staroukine, M1
Boomsma, F; de Boer, RA; Flesch, M; Pinto, YM; Pokharel, S; Suurmeijer, AJ; van Gilst, WH; van Kampen, DA; van Veldhuisen, DJ1
Armando, I; Baiardi, G; Bregonzio, C; Saavedra, JM; Seltzer, A1
Chen, K; Joseph, J; Joseph, L; Li, D; Mehta, JL1
Biswas, P; Centracchio, J; Dworkin, LD; Gong, R; Roy, A; Tolbert, E; Yango, A1
Hakam, AC; Hussain, T1
Delles, C; Fleischmann, EH; John, S; Schmidt, BM; Schmieder, RE; Schneider, MP1
Ando, T; Itoh, M; Joh, T; Kuno, A; Masuda, K; Nakamura, S; Nomura, T; Ogawa, K; Ohara, H; Okamoto, T; Shirai, T; Tang, M; Yamada, T1
Bivol, LM; Iversen, BM; Vågnes, OB1
Ino, K; Kajiyama, H; Kikkawa, F; Mizutani, S; Nagasaka, T; Shibata, K; Suganuma, T1
Ioroi, T; Iwao, H; Izumi, Y; Izumiya, Y; Kim-Mitsuyama, S; Tanaka, T; Wanibuchi, H; Yamamoto, E; Zhan, Y1
Nagane, Y; Obara, D; Terayama, Y; Utsugisawa, K; Utsugisawa, T1
De Backer, JP; Hunyady, L; Le, MT; Vanderheyden, PM; Vauquelin, G1
Becker, BN; Chiriva-Internati, M; Djamali, A; Hullett, DA; Jacobson, LM; Muehrer, RJ; Sprague, J; Thekkumkara, TJ; Weidanz, JA; Wittman, V1
Battegay, E; Zeller, A1
Eppel, GA; Evans, RG; Rajapakse, NW; Sampson, AK1
Awayda, MS; Fuller, AJ; Gonzalez-Villalobos, R; Hauschild, BC; Imig, JD; Inscho, EW; Navar, LG1
Blum, WF; Hauner, H; Skurk, T; van Harmelen, V1
Iigaya, K; Kawai, A; Kumagai, H; Matsuura, T; Onami, T; Onimaru, H; Oshima, N; Sakata, K; Saruta, T; Sugaya, T1
Ohashi, H; Takagi, H1
Cervenka, L; Husková, Z; Kopkan, L; Kramer, HJ; Skaroupková, P; Thurmová, M; Vanourková, Z1
Mitchell, KD; Mullins, JJ1
Ebinger, G; Hristova, I; Michotte, Y; Sarre, S; Stragier, B1
De Matteo, R; Head, GA; Mayorov, DN1
Harris, PJ; Hiranyachattada, S; Saetew, S1
Ichikawa, S; Kurabayashi, M; Miya, Y; Sakamaki, T; Sumino, H1
Armando, I; Bregonzio, C; Juorio, A; Macova, M; Pavel, J; Saavedra, JM; Sanchez-Lemus, E1
Bargetto, J; Galaz, A; Jalil, JE; Lavandero, S; Ocaranza, MP; Pérez, A1
Gao, J; Gessner, R; Köttgen, E; Niessen, H; Ohlemeyer, C; Roos, D; Wu, S1
De Cavanagh, EM; Ferder, L; Fraga, CG; Inserra, F; Piotrkowski, B; Stella, I; Toblli, JE1
Akutsu, H; Iwa, Y; Kizawa, H; Kondoh, R; Nagane, Y; Terayama, Y; Tohgi, H; Utsugisawa, K1
Ahn, YB; Cha, BY; Hong, OK; Jeong, IK; Kim, JW; Kim, MJ; Ko, SH; Son, HY; Song, KH; Yoon, KH1
Edvinsson, L; Malmsjö, M; Nilsson, E; Vikman, P; Wackenfors, A1
Dendorfer, A; Dodt, C; Dominiak, P; Jöhren, O; Pahlke, F; Raasch, W; Voges, I; Wittmershaus, C1
Cazaubon, S; Couraud, PO; Deshayes, F; Nahmias, C1
Delgiacco, E; Dou, J; Ge, L; Imboden, H; Macova, M; Nishioku, T; Pavel, J; Saavedra, JM; Yu, ZX; Zhou, J1
Jin, D; Katayama, H; Kishi, K; Miyazaki, M; Muramatsu, M; Takai, S; Tamai, H1
Frische, S; Frøkiaer, J; Jensen, AM; Knepper, MA; Li, C; Nielsen, S; Nørregaard, R; Praetorius, HA1
Clinckers, R; De Bundel, D; Ebinger, G; Meurs, A; Michotte, Y; Sarre, S; Smolders, I; Stragier, B1
Beutler, KT; Fenton, RA; Knepper, MA; Masilamani, S; Morris, RG; Packer, RK; Turban, S1
Fukushima Kusano, K; Hisamatsu, K; Ishihara, K; Kajiya, M; Miura, A; Miura, D; Miura, R; Morita, H; Nagase, S; Nakamura, K; Ohe, T1
Hirase, T; Inoue, T; Node, K; Wang, D1
Arenas, IA; Armstrong, SJ; Davidge, ST; Xu, Y1
Date, T; Kawai, M; Mochizuki, S; Seki, S; Shimizu, M; Taniguchi, I; Taniguchi, M; Yoshida, S1
Bautista, R; Franco, M; Herrera-Acosta, J; Johnson, RJ; Martínez, F; Montoya, A; Nepomuceno, T; Rodríguez-Iturbe, B; Santamaría, J; Tapia, E1
Ito, S; Sugawara, A1
Bie, P; Gammelgaard, I; Wamberg, S1
Piuhola, J; Ruskoaho, H; Szokodi, I1
Cai, H; Oak, JH1
Heidland, A; Kanase, N; Lakner, U; Rutkowski, P; Schmid, U; Schupp, N; Stopper, H1
Casselbrant, A; Edebo, A; Fändriks, L; Helander, HF; Lönroth, H; Lundell, L; Vieth, M; Wennerblom, J1
Fukui, D; Imaizumi, T; Kai, H; Kudo, H; Kuwahara, F; Mori, T; Sugi, Y; Tahara, N; Takayama, N; Takemiya, K; Tokuda, K; Yasukawa, H1
Cao, TB; Li, ZB; Liu, DY; Ma, LQ; Wang, LJ; Zhang, LL; Zhang, YP; Zhu, ZM1
Dworkin, LD; Gong, R; Rifai, A; Tolbert, EM; Yu, C1
Amara, AB; Jackson, MJ; McArdle, F; Rustom, R; Shalamanova, L1
Eskild-Jensen, A; Frøkiaer, J; Nyengaard, JR; Olesen, P; Paulsen, LF; Pedersen, L; Wogensen, L1
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Benicky, J; Saavedra, JM1
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Murakami, M; Nakagiri, A; Sunamoto, M1
Akazawa, H; Komuro, I; Qin, Y; Yasuda, N; Zou, Y1
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Baker, KM; Kumar, R; Singh, VP1
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Jugdutt, BI; Konig, A; Liu, P; Moe, G1
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Hirafuji, M; Iizuka, K; Kawaguchi, H; Machida, T1
Hattori, A; Ishii, M; Ishiura, S; Kobayashi, H; Mizutani, S; Murohara, T; Numaguchi, Y; Tsujimoto, M; Wright, JW1
Baker, KM; Khode, R; Kumar, R; Le, B; Singh, VP1
Fukumoto, M; Ikeda, T; Ishizaki, E; Jin, D; Miyazaki, M; Oku, H; Sakaguchi, M; Sakonjo, H; Sugiyama, T; Takai, S1
Banday, AA; Lokhandwala, MF1
Bae, EH; Fenton, RA; Frøkiaer, J; Jensen, AM; Kim, SW; Nielsen, S; Nørregaard, R1
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Higashikuni, Y; Hirata, Y; Koibuchi, N; Kugiyama, K; Nagai, R; Nakamura, K; Nishimatsu, H; Sata, M1
Benicky, J; Murakami, Y; Pavel, J; Saavedra, JM; Sanchez-Lemus, E1
Bursell, SE; Chilcote, TJ; Clermont, AC; Feener, EP; Phipps, JA; Sinha, S1
Raij, L; Schulman, IH; Zhou, MS1
Ding, G; Jia, R; Lv, J; Yang, D; Zhu, J1
Afzal, R; Floras, J; McKelvie, RS; Rouleau, JL; White, M; Yusuf, S1
Horie, M; Matsuura, H; Omatsu-Kanbe, M; Toyoda, F; Zankov, DP1
Nyengaard, JR; Razga, Z1
Fujimura, T; Fujita, H; Fushida, S; Harada, S; Hirakawa, K; Kayahara, M; Kinami, S; Kinoshita, J; Ninomiya, I; Ohta, T; Yagi, Y; Yashiro, M1
Fujikake, T; Fujioka, K; Hanamoto, T; Ikeda, T; Ishizuka, T; Kajita, K; Mori, I; Morita, H; Nagano, I; Okada, H; Takahashi, Y; Uno, Y; Zhiliang, W1
He, G; He, Y; Jing, T; Liu, J; Miao, L; Srivenugopal, KS; Wang, H1
Homma, I; Iigaya, K; Kobayashi, Y; Minoura, Y; Onimaru, H1
Hayashi, T; Inoue, N; Jin, D; Katayama, H; Kitaura, Y; Miyazaki, M; Muramatsu, M; Takai, S; Tamai, H1
Higuchi, T; Horikoshi, H; Hosono, Y; Matsumoto, M; Nakanishi, T; Nakayama, M; Ohsuzu, F; Okada, M; Suzuki, K; Takada, K1
Anegawa, T; Hirooka, Y; Ikeda, A; Imaizumi, T; Kai, H; Kajimoto, H; Kato, S; Koga, M; Kudo, H; Mifune, H; Mori, T; Takayama, N; Yasuoka, S1
Frøkiaer, J; Jonassen, T; Kim, SW; Knepper, MA; Kwon, TH; Lütken, SC; Marples, D; Nielsen, S1
Casselbrant, A; Edebo, A; Fändriks, L; Hallersund, P; Helander, HF; Jönson, C; Spak, E1
Akie, Y; Aritomi, S; Nakamura, Y; Nakayama, A; Satoh, Y; Sugiyama, A; Takahara, A; Wagatsuma, H1
Albiston, AL; Chai, SY; Dupont, AG; Gembardt, F; Smolders, I; Vanderheyden, P; Walther, T; Yang, R1
Fujii, M; Horie, M; Kawahara, C; Nishiyama, K; Tsutamoto, T; Yamaji, M; Yamamoto, T1
Hitomi, H; Hosomi, N; Kobori, H; Kohno, M; Masugata, H; Murao, K; Nakano, D; Nishiyama, A; Pelisch, N; Ueno, M1
Baron-Menguy, C; Cousin, M; Custaud, MA; Dumont, O; Guihot, AL; Henrion, D; Loufrani, L; Subra, JF; Toutain, B; Vessières, E2
Gemici, B; Izgüt-Uysal, VN; Ongüt, G; Tan, R1
Arun, SN; Bollag, WB; George, MV; Olala, L; Parker, PM; Shapiro, BA1
Masuyama, T; Matsumoto, M; Naito, Y; Ohyanagi, M; Okuda, S; Sakoda, T; Tsujino, T1
Coffman, TM; Facemire, C; Jensen, BL; Kjaersgaard, G; Madsen, K; Marcussen, N; Pedersen, M1
Bi, J; Chappell, MC; Contag, SA; Rose, JC1
Ichihara, A; Itoh, H; Kinouchi, K; Kurauchi-Mito, A; Murohashi-Bokuda, K; Narita, T; Nishiyama, A; Sakoda, M; Saleem, MA; Suzuki, F1
Kumagai, K1
Gao, YJ; Lee, RM; Lu, C; Su, LY1
Azegami, T; Hayashi, K; Ishiguro, K; Itoh, H; Sakamaki, Y; Sasamura, H1
Briggs, JP; Chen, L; Chen, M; Eisner, C; Gomez, RA; Huang, Y; Kim, SM; Li, L; Mizel, D; Oppermann, M; Schnermann, J; Sequeira Lopez, ML; Weinstein, LS1
Apablaza, F; Chiong, M; Godoy, I; Gonzalez, L; Hernandez, C; Jalil, JE; Lavandero, S; Lopez, R; Moya, J; Novoa, U; Ocaranza, MP; Pinto, M; Varas, M; Verdejo, H1
Arsenault, J; Cabana, J; Escher, E; Guillemette, G; Lanthier, L; Lavigne, P; Leduc, R; Lehoux, J1
Abidin, N; Choudhury, R; Garratt, CJ; Hall, MC; Kirubakaran, S; Peters, NS1
Guerra, MJ; Labandeira-Garcia, JL; Lanciego, JL; Rodriguez-Perez, AI; Valenzuela, R; Villar-Cheda, B1
Fujii, Y; Iino, Y; Isayama, H; Kamimura, H; Kihara, K1
Navar, LG; Seth, DM; Shao, W1
Agrawal, AN; Axtell, R; Ding, Z; Ho, PP; Lanz, TV; Luo, J; Platten, M; Srinagesh, H; Steinman, L; Wyss-Coray, T; Zhang, H1
Aslam, S; Griendling, K; Luo, Z; Teerlink, T; Welch, WJ; Wilcox, CS1
Kobori, H; Milani, CJ; Mitchell, KD; Mullins, JJ1
Danser, AH; van den Heuvel, M; van Esch, JH1
Ecelbarger, CM; Jose, PA; Li, F; Wang, X1
Guerra, MJ; Labandeira-Garcia, JL; Rodriguez-Perez, AI; Valenzuela, R; Villar-Cheda, B1
Chrousos, GP; Katsilambros, N; Kouskouni, E; Margeli, A; Mastorakos, G; Papassotiriou, I; Pavlatou, MG; Tentolouris, N1
Derosa, G; Fogari, R; Lazzari, P; Mugellini, A; Salvadeo, SA; Santoro, T; Zoppi, A1
Fu, H; Hitomi, H; Hosomi, N; Liu, G; Masugata, H; Matsumoto, M; Murao, K; Nishiyama, A; Pelisch, N; Ueno, M1
Mitsuyama, S1
Bahner, U; Grupp, C; Heidland, A; Klassen, A; Rutkowski, P; Schupp, N; Sebeková, K; Stopper, H1
Allen, AM; Bassi, JK; Delbridge, LM; O'Callaghan, EL; Porrello, ER; Thomas, WG1
Derosa, G; Fogari, R; Lazzari, P; Maffioli, P; Mugellini, A; Zoppi, A1
Karnik, SS; Kiya, Y; Matsuo, Y; Miura, S; Saku, K1
Gonzalez, AA; Kobori, H; Liu, L; McCormack, M; Navar, LG; Prieto, MC; Seth, DM1
Hata, M; Sezai, A; Shiono, M; Soma, M; Unosawa, S; Wakui, S; Yoshitake, I1
Banday, AA; Javkhedkar, AA; Lokhandwala, MF1
Agazatian, D; Bailey, JL; Coffman, TM; Farley, DB; Hong, S; Inagami, T; Kim, YH; Le, T; Matthews, SW; Pech, V; Verlander, JW; Wall, SM; Weiner, ID; Whitehill, FM1
Fu, H; Hosomi, N; Itano, T; Kohno, M; Liu, G; Masugata, H; Matsumoto, M; Miki, T; Nakano, D; Nishiyama, A; Pelisch, N; Sueda, Y; Ueno, M1
Fukui, A; Hara, M; Murozono, Y; Nagano-Torigoe, Y; Nakagawa, M; Ooie, T; Saikawa, T; Shinohara, T; Takahashi, N; Taniguchi, Y; Teshima, Y; Thuc, LC; Wakisaka, O; Yoshimatsu, H; Yufu, K1
Baumann, M; Heemann, U; Hermans, JJ; Lutz, J; Rusai, K; Schmaderer, C1
Iwao, H; Izumi, Y; Kita, H; Osada-Oka, M; Sato, T; Yagi, S1
El-Dahr, SS; Khalili, A; Preston, G; Song, R; Yosypiv, IV1
Denton, KM; Eppel, GA; Evans, RG; Head, GA1
Gabor, A; Leenen, FH2
Goshima, H; Ishizuka, T; Ozawa, A; Watanabe, Y1
Kittikulsuth, W; Pollock, DM; Pollock, JS1
Bell, JF; Carey, RM; Howell, NL; Kemp, BA; Navar, LG; Padia, SH; Rottkamp, DM; Shao, W1
Axelsson, J; Oberg, CM; Rippe, A; Rippe, B1
Li, YF; Yin, G; Zhang, CL; Zhang, H; Zhu, WY1
Baile, G; Gambini, J; Gíménez, I; Llinas, MT; Reverte, V; Salazar, FJ; Tapia, A1
Goel, R; Hanif, K; Najmi, AK; Nath, C; Pachauri, SD; Rajasekar, N; Tota, S1
Bivona, BJ; de Garavilla, L; Ford, SM; Harrison-Bernard, LM; Kobori, H; Park, S; Xu, S1
Albino-Teixeira, A; Fasching, A; Morato, M; Palm, F; Patinha, D; Pinho, D1
Dufield, D; Graneto, M; Llinas, MT; Masferrer, JL; Radabaugh, M; Reverte, V; Saez, F; Salazar, F; Salazar, FJ; Zweifel, B1
Almeida, AP; Damasceno, DD; Drummond, LR; Ferreira, AJ; Lima, MP; Motta, DF; Natali, AJ; Pesquero, JL; Quintão-Junior, JF1
Idikio, H; Jugdutt, BI; Jugdutt, C; Menon, V; Palaniyappan, A; Uwiera, RR1
Chaston, DJ; Edwards, FR; Hill, CE; Howitt, L; Matthaei, KI; Sandow, SL1
Cortes, MA; Ferrer, EG; Islas, MS; Lezama, L; Merino, MG; Puyol, MR; Rojo, T; Williams, PA1
Horio, N; Iwata, S; Margolskee, RF; Ninomiya, Y; Ohkuri, T; Sanematsu, K; Shigemura, N; Yasumatsu, K; Yoshida, R1
Borrajo, A; Diaz-Ruiz, C; Guerra, MJ; Labandeira-Garcia, JL; Rodriguez-Perez, AI1
Harris, RA; Sullivan, JC; Zimmerman, MA1
Amann, K; Brand, S; Mandel, P; Schupp, N; Zimnol, A1
Bathgate-Siryk, A; Dabul, S; Jafferjee, M; Koch, WJ; Lymperopoulos, A; McDonald, P; Sturchler, E; Valero, TR1
Fan, F; Jiang, G; Liu, Z; Lu, Y; Shen, C; Tao, L; Tian, C; Wu, H1
Gyombolai, P; Hunyady, L; Szalai, B; Tóth, AD; Turu, G; Várnai, P1
Jöhren, O; Mildner, M; Müller-Fielitz, H; Raasch, W; Steckelings, M; Stölting, I1
Huang, J; Liu, X; Lu, L; Niu, Y; Wang, Y; Yu, C; Yu, Y; Zhao, L; Zhou, L1
Bornstein, SR; Brown, NF; Brunssen, C; Eisenhofer, G; Frenzel, A; Hofmann, A; Morawietz, H; Peitzsch, M; Weldon, SM; Willenberg, HS; Ziegler, CG1
Inagaki, Y; Kaneko, S; Kitano, T; Ohkura, SI; Okamoto, Y; Sugimoto, N; Takamura, M; Takashima, SI; Takuwa, N; Takuwa, Y; Usui, S; Wada, T; Yoshioka, K1
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Cai, Y; Deng, H; Feng, Q; Li, Z; Qiu, S; Tian, W; Wang, X; Wang, Y; Wu, J1
Hu, G; Ito, O; Kohzuki, M; Miura, T; Muroya, Y; Ogawa, Y; Rong, R; Wang, W1
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Dang, Z; Jia, Q; Li, L; Ma, K; Si, J; Tan, C; Zhang, A; Zhang, X1
Casselbrant, A; Edebo, A; Fändriks, L; Hallersund, P; Spak, E1
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Huang, Q; Tian, S; Wu, T; Zheng, Y1

Reviews

26 review(s) available for candesartan and angiotensin ii

ArticleYear
Angiotensin II receptors.
    Journal of the American Society of Nephrology : JASN, 1999, Volume: 10 Suppl 11

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Endothelium; Humans; Imidazoles; Kidney; Losartan; Peptide Fragments; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles

1999
Mesangial AT1 receptors: expression, signaling, and regulation.
    Journal of the American Society of Nephrology : JASN, 1999, Volume: 10 Suppl 11

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Binding, Competitive; Biphenyl Compounds; Cells, Cultured; Gene Expression Regulation; Glomerular Mesangium; Humans; Losartan; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Signal Transduction; Tetrazoles

1999
Role of tissue angiotensin II in myocardial remodelling induced by mechanical stress.
    Journal of human hypertension, 1999, Volume: 13 Suppl 1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Hydralazine; Hypertension; Myocardium; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Stress, Mechanical; Tetrazoles; Ventricular Remodeling

1999
Intrarenal angiotensin II generation and renal effects of AT1 receptor blockade.
    Journal of the American Society of Nephrology : JASN, 1999, Volume: 10 Suppl 12

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Glomerular Filtration Rate; Hypertension, Renovascular; Kidney; Natriuresis; Rats; Receptors, Angiotensin; Renal Circulation; Renin-Angiotensin System; Tetrazoles

1999
Angiotensin and cerebral blood flow.
    Cellular and molecular neurobiology, 1999, Volume: 19, Issue:5

    Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cerebrovascular Circulation; Cerebrovascular Disorders; Homeostasis; Humans; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Tetrazoles

1999
Angiotensin-II receptor antagonists: their place in therapy.
    American family physician, 1999, Volume: 59, Issue:11

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Clinical Trials as Topic; Drug Administration Schedule; Drug Interactions; Heart Failure; Humans; Hypertension; Irbesartan; Losartan; Renin-Angiotensin System; Telmisartan; Tetrazoles; Valine; Valsartan

1999
Angiotensin II receptor antagonists in the treatment of hypertension.
    American family physician, 1999, Sep-15, Volume: 60, Issue:4

    Topics: Algorithms; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Humans; Hypertension; Irbesartan; Losartan; Receptors, Angiotensin; Telmisartan; Tetrazoles; Valine; Valsartan

1999
Angiotensin II antagonists for hypertension: are there differences in efficacy?
    American journal of hypertension, 2000, Volume: 13, Issue:4 Pt 1

    Topics: Angiotensin II; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Humans; Hypertension; Irbesartan; Losartan; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan

2000
Angiotensin receptor antagonists.
    Australian family physician, 2000, Volume: 29, Issue:7

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Humans; Hypertension; Irbesartan; Losartan; Telmisartan; Tetrazoles

2000
Putting the efficacy of candesartan cilexetil into perspective: a review of new comparative data.
    Journal of human hypertension, 2000, Volume: 14 Suppl 2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cattle; Cerebellum; Circadian Rhythm; Female; Heart; Humans; Hypertension; In Vitro Techniques; Irbesartan; Kinetics; Losartan; Male; Middle Aged; Prodrugs; Rabbits; Randomized Controlled Trials as Topic; Receptors, Angiotensin; Renin; Tetrazoles; Time Factors

2000
Expanded role for ARBs in cardiovascular and renal disease? Recent observations have far-reaching implications.
    Postgraduate medicine, 2001, Volume: 109, Issue:4

    Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biological Availability; Biphenyl Compounds; Cardiovascular Diseases; Humans; Imidazoles; Irbesartan; Kidney Diseases; Losartan; Metabolic Clearance Rate; Patient Selection; Renin-Angiotensin System; Telmisartan; Tetrazoles; Thiophenes; Treatment Outcome; Valine; Valsartan

2001
Angiotensin receptor blockers for chronic heart failure and acute myocardial infarction.
    Heart (British Cardiac Society), 2001, Volume: 86, Issue:1

    Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Drug Therapy, Combination; Heart Failure; Humans; Losartan; Models, Cardiovascular; Myocardial Infarction; Randomized Controlled Trials as Topic; Tetrazoles

2001
Dual angiotensin II blockade: a promise of enhanced renal protection?
    Journal of hypertension, 2002, Volume: 20, Issue:4

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Drug Synergism; Humans; Hypertension; Kidney Diseases; Proteinuria; Receptor, Angiotensin, Type 1; Tetrazoles

2002
Central angiotensin modulation of baroreflex control of renal sympathetic nerve activity in the rat: influence of dietary sodium.
    Acta physiologica Scandinavica, 2003, Volume: 177, Issue:3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Baroreflex; Benzimidazoles; Bicuculline; Biphenyl Compounds; Blood Pressure; Brain; Cerebral Ventricles; Kidney; Losartan; Medulla Oblongata; Paraventricular Hypothalamic Nucleus; Rats; Renin; Renin-Angiotensin System; Sodium, Dietary; Sympathetic Nervous System; Tetrazoles

2003
[Treatment for diastolic failure].
    Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61, Issue:5

    Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Diastole; Heart Failure; Humans; Losartan; Practice Guidelines as Topic; Receptor, Angiotensin, Type 1; Tetrazoles

2003
Angiotensin II AT1 receptor antagonists. Clinical implications of active metabolites.
    Journal of medicinal chemistry, 2003, Jun-05, Volume: 46, Issue:12

    Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Growth Hormone; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Models, Molecular; Receptor, Angiotensin, Type 1; Tetrazoles; Thiophenes; Thromboxane A2

2003
Multiple actions of angiotensin II in hypertension: benefits of AT1 receptor blockade.
    Journal of the American College of Cardiology, 2003, Sep-03, Volume: 42, Issue:5

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Fibrinolysis; Humans; Hypertension; Inflammation; Inflammation Mediators; Oxidative Stress; Reactive Oxygen Species; Tetrazoles

2003
Left ventricular hypertrophy regression with antihypertensive treatment: focus on Candesartan.
    Blood pressure. Supplement, 2003, Volume: 2

    Topics: Angiotensin II; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Electrocardiography; Humans; Hypertrophy, Left Ventricular; Renin-Angiotensin System; Tetrazoles; Treatment Outcome

2003
[Organ protection by angiotensin II receptor blockers].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl 3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cognition Disorders; Heart Failure; Humans; Hypertension; Kidney Diseases; Losartan; Membrane Proteins; Mineralocorticoid Receptor Antagonists; Proteins; Proteinuria; Randomized Controlled Trials as Topic; Stroke; Tetrazoles

2004
[Angiotensin II receptor blockers--evidence along the cardiovascular continuum].
    Praxis, 2005, Apr-13, Volume: 94, Issue:15

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Albuminuria; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dogs; Drug Therapy, Combination; Female; Heart Failure; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Myocardial Infarction; Placebos; Rabbits; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Risk Factors; Stroke; Tetrazoles; Time Factors

2005
[The Diabetic Retinopathy Candesartan Trials (DIRECT) programme].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 6

    Topics: Albuminuria; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Diabetic Retinopathy; Humans; Hypertension; Randomized Controlled Trials as Topic; Receptors, Vascular Endothelial Growth Factor; Renin-Angiotensin System; Retina; Risk Factors; Tetrazoles; Vascular Endothelial Growth Factor A

2005
[Endothelin-1, angiotensin II and cancer].
    Medecine sciences : M/S, 2006, Volume: 22, Issue:4

    Topics: Angiogenesis Inhibitors; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antineoplastic Agents; Benzimidazoles; Biphenyl Compounds; Clinical Trials as Topic; Endothelin-1; Humans; Neoplasm Invasiveness; Neoplasms; Neovascularization, Pathologic; Receptors, Angiotensin; Receptors, Endothelin; Tetrazoles

2006
[Stimulatory effects of angiotensin II on angiogenesis].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64 Suppl 5

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Diabetic Retinopathy; Humans; Neoplasms; Neovascularization, Pathologic; Neovascularization, Physiologic; Tetrazoles; Vascular Endothelial Growth Factor A

2006
Brain and peripheral angiotensin II play a major role in stress.
    Stress (Amsterdam, Netherlands), 2007, Volume: 10, Issue:2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Brain; Cold Temperature; Corticotropin-Releasing Hormone; Gastritis; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Restraint, Physical; Stress, Physiological; Tetrazoles

2007
A novel mechanism of mechanical stress-induced angiotensin II type 1-receptor activation without the involvement of angiotensin II.
    Naunyn-Schmiedeberg's archives of pharmacology, 2008, Volume: 377, Issue:4-6

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Cardiomegaly; Drug Inverse Agonism; Extracellular Signal-Regulated MAP Kinases; Humans; Receptor, Angiotensin, Type 1; Stress, Mechanical; Tetrazoles

2008
[Upstream approach for atrial fibrillation].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2010, Volume: 135, Issue:2

    Topics: Amiodarone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Fibrillation; Benzimidazoles; Biphenyl Compounds; Drug Therapy, Combination; Humans; Irbesartan; Tetrazoles

2010

Trials

26 trial(s) available for candesartan and angiotensin ii

ArticleYear
Angiotensin II antagonism and plasma radioreceptor-kinetics of candesartan in man.
    British journal of clinical pharmacology, 1998, Volume: 45, Issue:6

    Topics: Administration, Oral; Adult; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Humans; Male; Prodrugs; Rats; Receptors, Angiotensin; Tetrazoles

1998
Pharmacokinetics and pharmacodynamics of candesartan cilexetil in patients with normal to severely impaired renal function.
    European journal of clinical pharmacology, 1999, Volume: 54, Issue:12

    Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Female; Humans; Hypertension; Kidney; Kidney Diseases; Male; Middle Aged; Prodrugs; Renin; Tetrazoles

1999
Dose-dependent blockade of the angiotensin II type 1 receptor with losartan in normal volunteers.
    Journal of cardiovascular pharmacology, 2001, Volume: 37, Issue:6

    Topics: Adult; Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Female; Humans; Losartan; Male; Middle Aged; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Vasoconstrictor Agents

2001
Comparative angiotensin II receptor blockade in healthy volunteers: the importance of dosing.
    Clinical pharmacology and therapeutics, 2002, Volume: 71, Issue:1

    Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cross-Over Studies; Dose-Response Relationship, Drug; Humans; Irbesartan; Losartan; Male; Renin; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan

2002
The effects of candesartan on vascular responses to angiotensin II and norepinephrine in normal volunteers.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2001, Volume: 2, Issue:3

    Topics: Adult; Angiotensin II; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blood Vessels; Brachial Artery; Cross-Over Studies; Double-Blind Method; Female; Forearm; Humans; Injections, Intra-Arterial; Injections, Intravenous; Male; Norepinephrine; Reference Values; Regional Blood Flow; Tetrazoles; Time Factors; Vasoconstrictor Agents

2001
Pharmacodynamic studies on the angiotensin II type 1 antagonists irbesartan and candesartan based on angiotensin II dose response in humans.
    Journal of cardiovascular pharmacology, 2002, Volume: 39, Issue:4

    Topics: Adult; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Half-Life; Humans; Irbesartan; Male; Radioligand Assay; Receptor, Angiotensin, Type 1; Renin; Tetrazoles

2002
Forearm vasodilator response to angiotensin II in elderly women receiving candesartan: role of AT(2)- receptors.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2002, Volume: 3, Issue:1

    Topics: Aged; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cross-Over Studies; Double-Blind Method; Female; Forearm; Humans; Imidazoles; Middle Aged; Pyridines; Receptor, Angiotensin, Type 1; Regional Blood Flow; Tetrazoles; Vascular Resistance; Vasoconstrictor Agents; Vasodilation

2002
Angiotensin II type 1 receptor antagonism improves hypercholesterolemia-associated endothelial dysfunction.
    Arteriosclerosis, thrombosis, and vascular biology, 2002, Jul-01, Volume: 22, Issue:7

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biomarkers; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Cholesterol, LDL; Double-Blind Method; Endothelium, Vascular; Felodipine; Female; Forearm; Humans; Hypercholesterolemia; Inflammation; Male; Middle Aged; Prospective Studies; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Regional Blood Flow; Tetrazoles

2002
Influence of AT1 receptor blockade on blood pressure, renal haemodynamics and hormonal responses to intravenous angiotensin II infusion in hypertensive patients.
    Blood pressure, 2002, Volume: 11, Issue:4

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hypertension; Infusions, Intravenous; Losartan; Male; Middle Aged; Receptor, Angiotensin, Type 1; Renal Circulation; Renin; Tetrazoles; Valine; Valsartan

2002
Effect of candesartan, a type 1 angiotensin II receptor antagonist, on bronchial hyper-responsiveness to methacholine in patients with bronchial asthma.
    British journal of clinical pharmacology, 2002, Volume: 54, Issue:6

    Topics: Administration, Inhalation; Adult; Aged; Angiotensin II; Angiotensin Receptor Antagonists; Asthma; Benzimidazoles; Biphenyl Compounds; Bronchi; Bronchoconstrictor Agents; Cross-Over Studies; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Middle Aged; Tetrazoles

2002
Prophylactic treatment of migraine with an angiotensin II receptor blocker: a randomized controlled trial.
    JAMA, 2003, Jan-01, Volume: 289, Issue:1

    Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Cross-Over Studies; Double-Blind Method; Humans; Middle Aged; Migraine Disorders; Severity of Illness Index; Tetrazoles; Treatment Outcome

2003
Angiotensin II receptor blockade prevents acute renal sodium retention induced by low levels of orthostatic stress.
    Kidney international, 2004, Volume: 65, Issue:1

    Topics: Acute Disease; Adult; Angiotensin II; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cross-Over Studies; Heart Rate; Humans; Hypotension, Orthostatic; Kidney Tubules; Lower Body Negative Pressure; Male; Natriuresis; Sodium; Tetrazoles

2004
Rationale for the use of combination angiotensin-converting enzyme inhibitor and angiotensin II receptor blocker therapy in heart failure.
    Circulation journal : official journal of the Japanese Circulation Society, 2004, Volume: 68, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Drug Synergism; Drug Therapy, Combination; Exercise Tolerance; Female; Heart Failure; Heart Function Tests; Humans; Losartan; Male; Middle Aged; Natriuretic Peptide, Brain; Receptors, Angiotensin; Renin; Tetrazoles; Valine; Valsartan

2004
Comparison of effects of losartan, irbesartan, and candesartan on flow-mediated brachial artery dilation and on inflammatory and thrombolytic markers in patients with systemic hypertension.
    The American journal of cardiology, 2004, Jun-01, Volume: 93, Issue:11

    Topics: Angiotensin II; Antihypertensive Agents; Benzimidazoles; Biomarkers; Biphenyl Compounds; Brachial Artery; Double-Blind Method; Female; Humans; Hypertension; Irbesartan; Losartan; Male; Middle Aged; Tetrazoles; Vasodilation

2004
The effect of statins on angiotensin II-induced hemodynamic changes in young, mildly hypercholesterolemic men.
    American journal of hypertension, 2004, Volume: 17, Issue:12 Pt 1

    Topics: Adolescent; Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biomarkers; Biphenyl Compounds; Blood Pressure; Cholesterol, HDL; Cholesterol, LDL; Cross-Over Studies; Dose-Response Relationship, Drug; Heart Rate; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pyridines; Severity of Illness Index; Tetrazoles; Triglycerides; Vascular Resistance; Vasoconstrictor Agents

2004
Angiotensin II plays an important role in maintaining blood pressure in postmenopausal women receiving hormone replacement therapy.
    American journal of hypertension, 2005, Volume: 18, Issue:10

    Topics: Administration, Oral; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biomarkers; Biphenyl Compounds; Blood Pressure; Bradykinin; Drug Therapy, Combination; Epinephrine; Estrogens; Female; Heart Rate; Hormone Replacement Therapy; Humans; Middle Aged; Norepinephrine; Peptidyl-Dipeptidase A; Postmenopause; Renin; Tetrazoles; Treatment Outcome

2005
Effects of spironolactone during an angiotensin II receptor blocker treatment on the left ventricular mass reduction in hypertensive patients with concentric left ventricular hypertrophy.
    Circulation journal : official journal of the Japanese Circulation Society, 2006, Volume: 70, Issue:8

    Topics: Aged; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Echocardiography; Female; Heart Ventricles; Hemodynamics; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Natriuretic Peptide, Brain; Spironolactone; Tetrazoles; Ventricular Remodeling

2006
Actions by angiotensin II on esophageal contractility in humans.
    Gastroenterology, 2007, Volume: 132, Issue:1

    Topics: Aged; Aged, 80 and over; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Benzimidazoles; Biphenyl Compounds; Esophageal Sphincter, Lower; Esophagus; Female; Gene Expression; Humans; In Vitro Techniques; Male; Manometry; Middle Aged; Muscle Contraction; Peptidyl-Dipeptidase A; Peristalsis; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Tetrazoles; Vasoconstrictor Agents

2007
Exaggerated hypertensive response to exercise in patients with diastolic heart failure.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2008, Volume: 31, Issue:4

    Topics: Aged; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Echocardiography; Exercise; Exercise Test; Female; Heart Failure, Diastolic; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Quality of Life; Tetrazoles; Treatment Outcome

2008
Effects of enalapril, candesartan or both on neurohumoral activation and LV volumes and function in patients with heart failure not treated with a beta-blocker.
    Therapeutic advances in cardiovascular disease, 2009, Volume: 3, Issue:2

    Topics: Aged; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Double-Blind Method; Drug Therapy, Combination; Enalapril; Endothelin-1; Female; Heart Failure; Humans; Male; Middle Aged; Natriuretic Peptide, Brain; Norepinephrine; Peptide Fragments; Radionuclide Angiography; Stroke Volume; Tetrazoles; Treatment Outcome; Ventricular Function, Left

2009
Comparison of the long-term effects of candesartan and olmesartan on plasma angiotensin II and left ventricular mass index in patients with hypertension.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2010, Volume: 33, Issue:2

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Male; Middle Aged; Natriuretic Peptide, Brain; Peptidyl-Dipeptidase A; Tetrazoles

2010
Fibrinolysis and insulin sensitivity in imidapril and candesartan (FISIC study) recipients with hypertension.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2011, Volume: 34, Issue:4

    Topics: Adolescent; Adult; Aged; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Endothelium, Vascular; Female; Fibrinolysis; Humans; Hypertension; Imidazolidines; Insulin Resistance; Male; Middle Aged; Plasminogen Activator Inhibitor 1; Prospective Studies; Signal Transduction; Single-Blind Method; Tetrazoles; Tissue Plasminogen Activator; Treatment Outcome; Young Adult

2011
Role of angiotensin II in plasma PAI-1 changes induced by imidapril or candesartan in hypertensive patients with metabolic syndrome.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2011, Volume: 34, Issue:12

    Topics: Adolescent; Adult; Aged; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Blood Glucose; Blood Pressure; Body Mass Index; Cholesterol; Cholesterol, HDL; Female; Humans; Hypertension; Imidazolidines; Insulin; Male; Metabolic Syndrome; Middle Aged; Plasminogen Activator Inhibitor 1; Tetrazoles; Triglycerides; Young Adult

2011
Effects of olmesartan on the renin-angiotensin-aldosterone system for patients with essential hypertension after cardiac surgery--investigation using a candesartan change-over study.
    Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 2011, Volume: 17, Issue:5

    Topics: Aged; Aldosterone; Analysis of Variance; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Arteries; Benzimidazoles; Biphenyl Compounds; Cardiac Surgical Procedures; Compliance; Drug Substitution; Female; Hemodynamics; Humans; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Japan; Male; Middle Aged; Prospective Studies; Renin; Renin-Angiotensin System; Tetrazoles; Time Factors; Treatment Outcome

2011
Proteomic Approach to the Potential Role of Angiotensin II in Barrett Dysplasia.
    Proteomics. Clinical applications, 2019, Volume: 13, Issue:4

    Topics: Adult; Aged; Angiotensin II; Barrett Esophagus; Benzimidazoles; Biopsy; Biphenyl Compounds; Enalapril; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Neoplasm Proteins; Proteomics; Tetrazoles

2019
The human duodenal mucosa harbors all components for a local renin angiotensin system.
    Clinical science (London, England : 1979), 2019, 04-30, Volume: 133, Issue:8

    Topics: Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Duodenum; Female; Gastrointestinal Motility; Humans; Intestinal Mucosa; Losartan; Male; Middle Aged; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Renin-Angiotensin System; Tetrazoles; Young Adult

2019

Other Studies

364 other study(ies) available for candesartan and angiotensin ii

ArticleYear
Distinction between surmountable and insurmountable selective AT1 receptor antagonists by use of CHO-K1 cells expressing human angiotensin II AT1 receptors.
    British journal of pharmacology, 1999, Volume: 126, Issue:4

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Cattle; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Humans; Inositol Phosphates; Receptors, Angiotensin; Recombinant Proteins; Tetrazoles; Transfection

1999
Structural determinants of subtype selectivity and functional activity of angiotensin II receptors.
    Bioorganic & medicinal chemistry letters, 2016, Feb-15, Volume: 26, Issue:4

    Topics: Amino Acid Sequence; Angiotensin II Type 1 Receptor Blockers; Binding Sites; Ligands; Molecular Docking Simulation; Protein Binding; Protein Structure, Tertiary; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sequence Alignment

2016
Mimicking of Arginine by Functionalized N(ω)-Carbamoylated Arginine As a New Broadly Applicable Approach to Labeled Bioactive Peptides: High Affinity Angiotensin, Neuropeptide Y, Neuropeptide FF, and Neurotensin Receptor Ligands As Examples.
    Journal of medicinal chemistry, 2016, Mar-10, Volume: 59, Issue:5

    Topics: Angiotensin II; Arginine; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Ligands; Molecular Structure; Neuropeptide Y; Neurotensin; Oligopeptides; Peptide Fragments; Receptors, Angiotensin; Receptors, Neuropeptide; Receptors, Neurotensin; Structure-Activity Relationship

2016
Regional hemodynamic effects of the AT1 receptor antagonist CV-11974 in conscious renal hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 1995, Volume: 26, Issue:6 Pt 1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Consciousness; Hemodynamics; Hypertension, Renal; Laser-Doppler Flowmetry; Male; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Tetrazoles; Vasodilation

1995
Effects of an angiotensin II receptor antagonist, CV-11974, on angiotensin II-induced increases in cytosolic free calcium concentration, hyperplasia, and hypertrophy of cultured vascular smooth muscle cells.
    Journal of cardiovascular pharmacology, 1994, Volume: 23, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Benzimidazoles; Biphenyl Compounds; Calcium; Cells, Cultured; Cytosol; Dinoprost; DNA; Fura-2; Hyperplasia; Hypertrophy; Ionomycin; Muscle Proteins; Muscle, Smooth, Vascular; Rats; Rats, Wistar; Tetrazoles

1994
Angiotensin II inhibits cytokine-stimulated inducible nitric oxide synthase expression in vascular smooth muscle cells.
    The Journal of biological chemistry, 1994, Apr-15, Volume: 269, Issue:15

    Topics: Amino Acid Oxidoreductases; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Diglycerides; Enzyme Induction; Humans; Imidazoles; Interleukin-1; Kinetics; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Pyridines; Rats; Recombinant Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Tetrazoles; Tumor Necrosis Factor-alpha

1994
Protein kinase cascade activated by mechanical stress in cardiocytes: possible involvement of angiotensin II.
    European heart journal, 1995, Volume: 16 Suppl C

    Topics: Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Gene Expression; Mitogen-Activated Protein Kinase Kinases; Myocardium; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-raf; Rats; Rats, Wistar; Stress, Mechanical; Tetrazoles

1995
Angiotensin II stimulates interleukin-6 release from cultured mouse mesangial cells.
    Journal of the American Society of Nephrology : JASN, 1995, Volume: 6, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Cell Division; Cells, Cultured; DNA; Gene Expression; Glomerular Mesangium; Glomerulonephritis, Membranoproliferative; Interleukin-6; Kinetics; Mice; RNA, Messenger; Tetrazoles

1995
Angiotensin II receptor antagonist CV-11974 and cerebral blood flow autoregulation.
    Journal of hypertension, 1995, Volume: 13, Issue:7

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cerebrovascular Circulation; Homeostasis; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles

1995
Angiotensin II partly mediates mechanical stress-induced cardiac hypertrophy.
    Circulation research, 1995, Volume: 77, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Cardiomegaly; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Mitogen-Activated Protein Kinase Kinases; Myocardium; Phenylalanine; Protein Kinases; Rats; Rats, Wistar; Receptors, Angiotensin; Saralasin; Signal Transduction; Stress, Mechanical; Tetrazoles

1995
Effects of TCV-116 and CV-11974 on angiotensin II-induced responses in vascular smooth muscle cells.
    European journal of pharmacology, 1995, Apr-28, Volume: 289, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Benzimidazoles; Binding, Competitive; Biphenyl Compounds; Muscle, Smooth, Vascular; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Tetrazoles

1995
Angiotensin II transduces its signal to focal adhesions via angiotensin II type 1 receptors in vascular smooth muscle cells.
    FEBS letters, 1995, Jul-17, Volume: 368, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Cytoskeletal Proteins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Imidazoles; Muscle, Smooth, Vascular; Paxillin; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Pyridines; Rats; Receptors, Angiotensin; Signal Transduction; Tetrazoles

1995
Effect of captopril and angiotensin II receptor blockade on pressure natriuresis in transgenic TGR(mRen-2)27 rats.
    Hypertension (Dallas, Tex. : 1979), 1995, Volume: 26, Issue:3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Genetically Modified; Benzimidazoles; Biphenyl Compounds; Captopril; Glomerular Filtration Rate; Kidney; Male; Natriuresis; Rats; Rats, Sprague-Dawley; Renal Circulation; Renin; Tetrazoles

1995
Angiotensin II Receptor Antagonists: Can they Go Beyond ACE Inhibitors? Proceedings of a satellite symposium to the 15th scientific meeting of the International Society of Hypertension. Melbourne, Australia, March 1994.
    Blood pressure. Supplement, 1994, Volume: 5

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Humans; Hypertension; Tetrazoles

1994
Angiotensin II subtype 1 receptor modulates epinephrine release from isolated rat adrenal gland.
    Blood pressure. Supplement, 1994, Volume: 5

    Topics: Adrenal Glands; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Epinephrine; Male; Rats; Rats, Wistar; Receptors, Angiotensin; Tetrazoles

1994
Activated angiotensin II generation and regulation in rat mesenteric arteries following nephrectomy.
    Blood pressure. Supplement, 1994, Volume: 5

    Topics: Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Feedback; Hypertension; Kidney; Male; Mesenteric Arteries; Nephrectomy; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; Tetrazoles

1994
Effects of CV-11974 on renal haemodynamics and renal function in dogs.
    Blood pressure. Supplement, 1994, Volume: 5

    Topics: Anesthesia; Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Dogs; Infusions, Intra-Arterial; Kidney; Kidney Tubules; Pentobarbital; Renal Circulation; Tetrazoles

1994
Effect of an AT1 receptor antagonist (CV-11974) on angiotensin II-induced cardiomyocyte hypertrophy in vitro.
    Blood pressure. Supplement, 1994, Volume: 5

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blotting, Northern; Cardiomegaly; Cells, Cultured; DNA, Complementary; Endothelin-1; Endothelins; Heart; Imidazoles; Muscle, Smooth, Vascular; Myocardium; Protein Precursors; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Receptors, Endothelin; RNA, Messenger; Tetrazoles

1994
Angiotensin II inhibition of L-type Ca2+ current in sinoatrial node cells of rabbits.
    The American journal of physiology, 1995, Volume: 268, Issue:3 Pt 2

    Topics: Acetylcholine; Action Potentials; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Calcium; Cyclic AMP-Dependent Protein Kinases; Heart Rate; In Vitro Techniques; Intracellular Fluid; Ion Transport; Kinetics; Membrane Potentials; Myocardial Contraction; Rabbits; Renin-Angiotensin System; Sinoatrial Node; Tetrazoles

1995
Effect of an angiotensin II receptor antagonist, CV-11974, and its prodrug, TCV-116, on production of aldosterone.
    European journal of pharmacology, 1994, Feb-21, Volume: 253, Issue:1-2

    Topics: Administration, Oral; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Corticosterone; Hypertension; Imidazoles; Infusions, Intravenous; Male; Pyridines; Rabbits; Rats; Rats, Inbred SHR; Rats, Wistar; Tetrazoles; Zona Glomerulosa

1994
Pharmacological profile of a highly potent and long-acting angiotensin II receptor antagonist, 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4- yl]methyl]-1H-benzimidazole-7-carboxylic acid (CV-11974), and its prodrug, (+/-)-1-(cyclohexyloxycarbonyloxy)-ethy
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 266, Issue:1

    Topics: Adrenal Cortex; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cattle; Imidazoles; In Vitro Techniques; Iodine Radioisotopes; Kinetics; Losartan; Male; Muscle Contraction; Muscle, Smooth, Vascular; Prodrugs; Protein Binding; Rabbits; Rats; Rats, Sprague-Dawley; Substrate Specificity; Tetrazoles

1993
Inhibition of rabbit aortic angiotensin II (AII) receptor by CV-11974, a new nonpeptide AII antagonist.
    Biochemical pharmacology, 1993, Jul-20, Volume: 46, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Benzimidazoles; Binding Sites; Binding, Competitive; Biphenyl Compounds; Iodine Radioisotopes; Isomerism; Male; Rabbits; Tetrazoles

1993
Brain angiotensin II contributes to the development of hypertension in Dahl-Iwai salt-sensitive rats.
    Journal of hypertension, 1995, Volume: 13, Issue:8

    Topics: Angiotensin II; Animals; Arteries; Baroreflex; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Brain; Drug Resistance; Heart Rate; Hormones; Hypertension; Injections, Intraventricular; Male; Rats; Rats, Inbred Strains; Sodium Chloride; Tetrazoles

1995
Angiotensin II induces ovulation and oocyte maturation in rabbit ovaries via the AT2 receptor subtype.
    Endocrinology, 1996, Volume: 137, Issue:4

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Benzimidazoles; Biphenyl Compounds; Cellular Senescence; Female; Imidazoles; Oocytes; Ovary; Ovulation Induction; Pyridines; Rabbits; Receptors, Angiotensin; Saralasin; Tetrazoles

1996
The angiotensin receptor antagonist 2-ethoxy-1-[[2'-(1H- tetrazol-5-yl) biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylic acid (CV11974) attenuates the tubuloglomerular feedback response during NO synthase blockade in rats.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 277, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arginine; Benzimidazoles; Biphenyl Compounds; Feedback; Hemodynamics; Homeostasis; Kidney Glomerulus; Kidney Tubules; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Tetrazoles

1996
Inhibitory effect of an angiotensin II type 1 receptor antagonist on growth of vascular smooth muscle cells from spontaneously hypertensive rats.
    Journal of cardiovascular pharmacology, 1996, Volume: 27, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Cell Division; DNA; Indans; Male; Muscle, Smooth, Vascular; Prodrugs; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles; Vasoconstrictor Agents

1996
CV-11974, the active metabolite of TCV-116 (Candesarten), inhibits the synergistic or additive effect of different growth factors on angiotensin II-induced proliferation of vascular smooth muscle cells.
    Biochemical pharmacology, 1996, Jul-12, Volume: 52, Issue:1

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Becaplermin; Benzimidazoles; Biphenyl Compounds; Cell Division; Cells, Cultured; Drug Synergism; Epidermal Growth Factor; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Rats; Rats, Inbred WKY; Tetrazoles

1996
A long-term receptor stimulation is requisite for angiotensin II-dependent DNA synthesis in vascular smooth muscle cells from spontaneously hypertensive rats.
    European journal of pharmacology, 1995, Nov-30, Volume: 291, Issue:3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Base Sequence; Benzimidazoles; Biphenyl Compounds; Calcium; Cells, Cultured; DNA Replication; Fibroblast Growth Factor 2; Imidazoles; In Vitro Techniques; Losartan; Molecular Sequence Data; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Pyridines; Rats; Rats, Inbred SHR; Receptors, Platelet-Derived Growth Factor; Tetrazoles

1995
Angiotensin type 1 receptor antagonists CV-11974 and EXP 3174 cause selective renal vasodilatation in conscious spontaneously hypertensive rats.
    Clinical science (London, England : 1979), 1996, Volume: 91, Issue:2

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Imidazoles; Losartan; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Circulation; Tetrazoles; Vasodilation

1996
Carbocyclic thromboxane A2 enhances the angiotensin II-induced DNA synthesis in smooth muscle cells.
    European journal of pharmacology, 1996, Jun-20, Volume: 307, Issue:1

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cell Division; Cells, Cultured; DNA; Muscle, Smooth, Vascular; Platelet Aggregation Inhibitors; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred WKY; RNA, Messenger; Tetrazoles; Thromboxane A2; Vasoconstrictor Agents

1996
The presence of angiotensin II receptors in elasmobranchs.
    General and comparative endocrinology, 1997, Volume: 105, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Atrial Natriuretic Factor; Benzimidazoles; Binding, Competitive; Biphenyl Compounds; Bradykinin; Branchial Region; Dose-Response Relationship, Drug; Elasmobranchii; Iodine Radioisotopes; Membrane Proteins; Natriuretic Peptide, C-Type; Oligopeptides; Proteins; Radioligand Assay; Receptors, Angiotensin; Tetrazoles; Time Factors; Tissue Distribution

1997
Candesartan (CV-11974) dissociates slowly from the angiotensin AT1 receptor.
    European journal of pharmacology, 1997, Jan-14, Volume: 319, Issue:1

    Topics: Adrenal Cortex; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Cattle; Imidazoles; In Vitro Techniques; Losartan; Male; Rabbits; Receptors, Angiotensin; Tetrazoles; Vasoconstriction

1997
Angiotensin-converting enzyme inhibitor up-regulates cardiac beta-receptors in cultured neonatal rat myocytes.
    Japanese circulation journal, 1997, Volume: 61, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Benzimidazoles; Biphenyl Compounds; Captopril; Cells, Cultured; Myocardial Contraction; Myocardium; Radioligand Assay; Rats; Receptors, Adrenergic, beta; Tetrazoles; Up-Regulation

1997
Mapping of angiotensin II receptor subtypes in peripheral tissues of spontaneously hypertensive rats by in vitro autoradiography.
    Clinical and experimental pharmacology & physiology. Supplement, 1995, Volume: 22, Issue:1

    Topics: Adrenal Glands; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Benzimidazoles; Biphenyl Compounds; Heart; Hypertension; Kidney; Male; Muscle, Smooth, Vascular; Myocardium; Oligopeptides; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Tetrazoles

1995
Stimulation of angiotensin subtype 2 receptor reduces basal cGMP levels in the neointima of rat aorta after balloon injury.
    General pharmacology, 1997, Volume: 28, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Benzimidazoles; Biphenyl Compounds; Catheterization; Cyclic AMP; Cyclic GMP; Imidazoles; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Pyridines; Rats; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Tunica Intima

1997
Stretch-induced MAP kinase activation in cardiomyocytes of angiotensinogen-deficient mice.
    Biochemical and biophysical research communications, 1997, Jun-09, Volume: 235, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Benzimidazoles; Biphenyl Compounds; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Activation; Gene Targeting; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Myocardium; Peptides, Cyclic; Renin-Angiotensin System; Tetrazoles

1997
Role of the angiotensin II type 1 receptor in preconditioning against infarction.
    Coronary artery disease, 1997, Volume: 8, Issue:6

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Rabbits; Radioimmunoassay; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles

1997
Analysis of the effects of candesartan in the mesenteric vascular bed of the cat.
    Hypertension (Dallas, Tex. : 1979), 1997, Volume: 30, Issue:5

    Topics: Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Vessels; Cats; Female; Imidazoles; Male; Perfusion; Pressure; Pyridines; Splanchnic Circulation; Tetrazoles

1997
Enhancement by exogenous and locally generated angiotensin II of purinergic neurotransmission via angiotensin type 1 receptor in the guinea-pig isolated mesenteric artery.
    British journal of pharmacology, 1997, Volume: 122, Issue:5

    Topics: Adenosine Triphosphate; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Electric Stimulation; Evoked Potentials; Female; Guinea Pigs; Imidazoles; In Vitro Techniques; Membrane Potentials; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Oligopeptides; Purinergic P2 Receptor Antagonists; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Suramin; Synaptic Transmission; Tetrazoles; Vasoconstrictor Agents

1997
Possible role of P-450 metabolite of arachidonic acid in vasodilator mechanism of angiotensin II type 2 receptor in the isolated microperfused rabbit afferent arteriole.
    The Journal of clinical investigation, 1997, Dec-01, Volume: 100, Issue:11

    Topics: 8,11,14-Eicosatrienoic Acid; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arachidonic Acid; Arterioles; Benzimidazoles; Biphenyl Compounds; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Endothelium, Vascular; Humans; Imidazoles; In Vitro Techniques; Kidney Glomerulus; Large-Conductance Calcium-Activated Potassium Channels; Male; Norepinephrine; Perfusion; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Pyridines; Rabbits; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetraethylammonium; Tetrazoles; Vasoconstrictor Agents; Vasodilator Agents

1997
Function of angiotensin II type 2 receptor in the postglomerular efferent arteriole.
    Kidney international. Supplement, 1997, Volume: 63

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arterioles; Benzimidazoles; Biphenyl Compounds; Imidazoles; In Vitro Techniques; Male; Microcirculation; Norepinephrine; Pyridines; Rabbits; Receptors, Angiotensin; Renal Circulation; Tetrazoles; Vasodilation

1997
Pharmacological profiles of a novel non-peptide angiotensin II type I receptor antagonist HR720 in vitro and in vivo.
    Japanese journal of pharmacology, 1997, Volume: 75, Issue:3

    Topics: Adrenal Glands; Adult; Aged; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cricetinae; Humans; Imidazoles; In Vitro Techniques; Losartan; Male; Mesocricetus; Middle Aged; Muscle, Smooth, Vascular; Rabbits; Rats; Tetrazoles; Thermodynamics

1997
Central amino acids mediate cardiovascular response to angiotensin II in the rat.
    Brain research bulletin, 1998, Volume: 45, Issue:2

    Topics: Adrenergic alpha-Agonists; Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Brain Chemistry; Heart Rate; Hemodynamics; Injections, Intraventricular; Male; Microdialysis; Microinjections; Neurotransmitter Agents; Nitroglycerin; Phenylephrine; Rats; Rats, Inbred SHR; Tetrazoles; Vasodilator Agents

1998
Responses to angiotensin peptides are mediated by AT1 receptors in the rat.
    The American journal of physiology, 1998, Volume: 274, Issue:1

    Topics: Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Female; Hindlimb; Imidazoles; Losartan; Male; Norepinephrine; Peptide Fragments; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles

1998
Murine double nullizygotes of the angiotensin type 1A and 1B receptor genes duplicate severe abnormal phenotypes of angiotensinogen nullizygotes.
    The Journal of clinical investigation, 1998, Feb-15, Volume: 101, Issue:4

    Topics: Adrenal Glands; Anesthetics; Angiotensin II; Angiotensinogen; Animals; Benzimidazoles; beta-Galactosidase; Biphenyl Compounds; Blood Pressure; Imidazoles; Infusions, Intravenous; Kidney; Losartan; Mice; Mice, Knockout; Myocardium; Phenotype; Pyridines; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Saralasin; Staining and Labeling; Tetrazoles; Thiopental; Zygote

1998
Biphasic activation of the JAK/STAT pathway by angiotensin II in rat cardiomyocytes.
    Circulation research, 1998, Feb-09, Volume: 82, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Cardiomegaly; Cells, Cultured; Interferon-gamma; Interferons; Janus Kinase 2; Myocardium; Phosphorylation; Phosphotransferases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Rats; Rats, Wistar; Signal Transduction; Stereoisomerism; Tetrazoles; Trans-Activators; Tyrosine

1998
Role of ion channels and exchangers in mechanical stretch-induced cardiomyocyte hypertrophy.
    Circulation research, 1998, Mar-09, Volume: 82, Issue:4

    Topics: Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Calcium-Calmodulin-Dependent Protein Kinases; Cardiomegaly; Cytoplasm; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Guanidines; Hydrogen-Ion Concentration; Ion Channels; MAP Kinase Kinase 1; Mechanoreceptors; Mitogen-Activated Protein Kinase Kinases; Muscle Proteins; Peptides, Cyclic; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-raf; Rats; Rats, Wistar; Signal Transduction; Sodium-Hydrogen Exchangers; Sulfones; Tetrazoles

1998
Interaction of myocytes and nonmyocytes is necessary for mechanical stretch to induce ANP/BNP production in cardiocyte culture.
    Journal of cardiovascular pharmacology, 1998, Volume: 31 Suppl 1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Atrial Natriuretic Factor; Benzimidazoles; Biphenyl Compounds; Cell Communication; Cells, Cultured; Coculture Techniques; Myocardium; Natriuretic Peptide, Brain; Nerve Tissue Proteins; Physical Stimulation; Rats; Tetrazoles

1998
Activation of angiotensinogen gene in cardiac myocytes by angiotensin II and mechanical stretch.
    The American journal of physiology, 1998, Volume: 275, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Animals, Newborn; Benzimidazoles; beta-Galactosidase; Biphenyl Compounds; Cells, Cultured; Chloramphenicol O-Acetyltransferase; Cycloheximide; Dactinomycin; Gene Expression Regulation; Heart; Heart Ventricles; Imidazoles; Liver; Lung; Myocardium; Promoter Regions, Genetic; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Recombinant Fusion Proteins; RNA, Messenger; RNA, Ribosomal, 18S; Stress, Mechanical; Tetrazoles; Transcription, Genetic; Transfection

1998
Angiotensin II and intracellular calcium of adult cardiac fibroblasts.
    Journal of molecular and cellular cardiology, 1998, Volume: 30, Issue:6

    Topics: Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Calcium; Collagen; Culture Media; Dose-Response Relationship, Drug; Egtazic Acid; Fetal Blood; Fibroblasts; Fura-2; Heart Ventricles; Imidazoles; Pyridines; Rats; Spectrometry, Fluorescence; Tetrazoles

1998
Functional evidence for alternative ANG II-forming pathways in hamster cardiovascular system.
    The American journal of physiology, 1998, Volume: 275, Issue:4

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Aprotinin; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Captopril; Chymases; Cricetinae; Heart Ventricles; Humans; In Vitro Techniques; Male; Mesocricetus; Muscle Contraction; Muscle, Smooth, Vascular; Myocardium; Oligopeptides; Serine Endopeptidases; Substrate Specificity; Tetrazoles; Vasoconstriction

1998
Effects of renin-angiotensin system blockade and dietary salt intake on left ventricular hypertrophy in Dahl salt-sensitive rats.
    Hypertension research : official journal of the Japanese Society of Hypertension, 1998, Volume: 21, Issue:3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Diet; Hypertrophy, Left Ventricular; Rats; Rats, Inbred Strains; Renin; Renin-Angiotensin System; Sodium, Dietary; Tetrazoles; Time Factors

1998
Central and peripheral mechanisms involved in hypertension induced by chronic inhibition of nitric oxide synthase in rats.
    Journal of hypertension, 1998, Volume: 16, Issue:8

    Topics: Acute Disease; Adrenergic alpha-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Chronic Disease; Denervation; Enzyme Inhibitors; Hypertension; Injections, Intravenous; Injections, Intraventricular; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phentolamine; Rats; Rats, Wistar; Sinoatrial Node; Tetrazoles

1998
Roles of brain angiotensin II and C-type natriuretic peptide in deoxycorticosterone acetate-salt hypertension in rats.
    Journal of hypertension, 1998, Volume: 16, Issue:8

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arginine Vasopressin; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Brain; Desoxycorticosterone; Hypertension; Infusions, Parenteral; Injections, Intravenous; Injections, Intraventricular; Male; Natriuretic Peptide, C-Type; Rats; Rats, Wistar; Sodium Chloride; Tetrazoles

1998
Interactions between the renin-angiotensin system (RAS) and the sympathetic system.
    Basic research in cardiology, 1998, Volume: 93 Suppl 2

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Dose-Response Relationship, Drug; Imidazoles; Losartan; Male; Norepinephrine; Presynaptic Terminals; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Renin-Angiotensin System; Sympathetic Nervous System; Tetrazoles; Vasoconstrictor Agents

1998
Angiotensin II stimulates both aldosterone secretion and DNA synthesis via type 1 but not type 2 receptors in bovine adrenocortical cells.
    Journal of endocrinological investigation, 1998, Volume: 21, Issue:10

    Topics: Adrenal Cortex; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Cattle; Cells, Cultured; DNA; Imidazoles; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Zona Glomerulosa

1998
Angiotensin II interferes with leukemia inhibitory factor-induced STAT3 activation in cardiac myocytes.
    Biochemical and biophysical research communications, 1998, Dec-09, Volume: 253, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Cytoprotection; DNA-Binding Proteins; Dose-Response Relationship, Drug; Growth Inhibitors; Heart Ventricles; Humans; Interleukin-6; Leukemia Inhibitory Factor; Lymphokines; Mice; Myocardium; Phosphorylation; Rats; Rats, Sprague-Dawley; Signal Transduction; STAT3 Transcription Factor; Tetrazoles; Trans-Activators; Tyrosine

1998
The effects of candesartan on human AT1 receptor-expressing Chinese hamster ovary cells.
    Journal of the American Society of Nephrology : JASN, 1999, Volume: 10 Suppl 11

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Inositol Phosphates; Lithium Chloride; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Transfection

1999
AT1 calcium signaling in renal vascular smooth muscle cells.
    Journal of the American Society of Nephrology : JASN, 1999, Volume: 10 Suppl 11

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Calcium; Calcium Signaling; Cells, Cultured; Egtazic Acid; Kidney Glomerulus; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles

1999
The influence of candesartan and PD123319 on responses to angiotensin II in the hindquarters vascular bed of the rat.
    Journal of the American Society of Nephrology : JASN, 1999, Volume: 10 Suppl 11

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Calcium Channel Agonists; Dose-Response Relationship, Drug; Female; Hemodynamics; Hindlimb; Imidazoles; Injections, Intravenous; Male; Norepinephrine; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles; Vasoconstrictor Agents

1999
Effects of candesartan and PD123319 on responses to angiotensin II in the anesthetized mouse.
    Journal of the American Society of Nephrology : JASN, 1999, Volume: 10 Suppl 11

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Epinephrine; Imidazoles; Mice; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles

1999
Analysis of the effects of candesartan on responses to angiotensin II in the hindquarters vascular bed of the cat.
    Journal of the American Society of Nephrology : JASN, 1999, Volume: 10 Suppl 11

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cats; Dose-Response Relationship, Drug; Female; Hindlimb; Male; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles; Time Factors; Vasoconstrictor Agents; Vasodilator Agents

1999
Renal responses of the nonclipped kidney of two-kidney/one-clip Goldblatt hypertensive rats to type 1 angiotensin II receptor blockade with candesartan.
    Journal of the American Society of Nephrology : JASN, 1999, Volume: 10 Suppl 11

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Glomerular Filtration Rate; Hypertension, Renal; Kidney; Male; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Regional Blood Flow; Sodium; Tetrazoles; Time Factors; Vasodilation

1999
Effects of candesartan on angiotensin II-induced renal vasoconstriction in rats and mice.
    Journal of the American Society of Nephrology : JASN, 1999, Volume: 10 Suppl 11

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Dose-Response Relationship, Drug; Hypertension; Kidney; Mice; Mice, Knockout; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Regional Blood Flow; Renal Artery; Tetrazoles; Time Factors; Vasoconstriction

1999
Nitric oxide participates in the renal vasodilatory effect of candesartan in anesthetized rats.
    Journal of the American Society of Nephrology : JASN, 1999, Volume: 10 Suppl 11

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arginine; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Regional Blood Flow; Tetrazoles; Vasodilation

1999
AT1 receptor inhibition blunts angiotensin II-stimulated nitric oxide release in renal arteries.
    Journal of the American Society of Nephrology : JASN, 1999, Volume: 10 Suppl 11

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Endothelium, Vascular; In Vitro Techniques; Losartan; Male; Microelectrodes; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renal Artery; Tetrazoles; Vasoconstriction

1999
Angiotensin II stimulates macula densa basolateral sodium/hydrogen exchange via type 1 angiotensin II receptors.
    Journal of the American Society of Nephrology : JASN, 1999, Volume: 10 Suppl 11

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney Glomerulus; Rabbits; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Signal Transduction; Sodium-Hydrogen Exchangers; Tetrazoles

1999
Proximal tubular angiotensin II levels and renal functional responses to AT1 receptor blockade in nonclipped kidneys of Goldblatt hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 33, Issue:1

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Data Interpretation, Statistical; Glomerular Filtration Rate; Hypertension, Renovascular; Kidney; Kidney Tubules, Proximal; Male; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renal Circulation; Renin-Angiotensin System; Tetrazoles

1999
Angiotensin II type 1 receptor-mediated peroxide production in human macrophages.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 33, Issue:1 Pt 2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Cell Differentiation; Humans; Imidazoles; Kinetics; Leukemia, Monocytic, Acute; Macrophages; Oxidative Stress; Peroxides; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetradecanoylphorbol Acetate; Tetrazoles; Tumor Cells, Cultured

1999
Cardioprotective effect of angiotensin-converting enzyme inhibition against hypoxia/reoxygenation injury in cultured rat cardiac myocytes.
    Circulation, 1999, Feb-16, Volume: 99, Issue:6

    Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Bradykinin; Cell Hypoxia; Cells, Cultured; Cilazapril; Creatine Kinase; Cyclic GMP; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Guanidines; Indomethacin; Methylene Blue; Muscle Fibers, Skeletal; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxygen; Rats; Rats, Wistar; Staurosporine; Tetrazoles

1999
Blocking angiotensin II ameliorates proteinuria and glomerular lesions in progressive mesangioproliferative glomerulonephritis.
    Kidney international, 1999, Volume: 55, Issue:3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Bradykinin; Bradykinin Receptor Antagonists; Cilazapril; Collagen; Disease Models, Animal; Glomerulonephritis, Membranoproliferative; Hydralazine; Kidney Failure, Chronic; Male; Proteinuria; Rats; Rats, Wistar; Renal Circulation; Renin-Angiotensin System; Tetrazoles; Transforming Growth Factor beta

1999
Differential kinetics of circulating angiotensin IV and II after treatment with angiotensin II type 1 receptor antagonist and their plasma levels in patients with chronic renal failure.
    Clinical nephrology, 1999, Volume: 51, Issue:2

    Topics: Aged; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Female; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Rats; Rats, Wistar; Renal Dialysis; Tetrazoles

1999
Resetting of exaggerated tubuloglomerular feedback activity in acutely volume-expanded young SHR.
    The American journal of physiology, 1999, Volume: 276, Issue:3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Feedback; Kidney Glomerulus; Kidney Tubules; Loop of Henle; Perfusion; Plasma Substitutes; Pressure; Punctures; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Sodium Chloride; Tetrazoles

1999
Binding of the antagonist [3H]candesartan to angiotensin II AT1 receptor-transfected [correction of tranfected] Chinese hamster ovary cells.
    European journal of pharmacology, 1999, Feb-19, Volume: 367, Issue:2-3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; CHO Cells; Computer Simulation; Cricetinae; Female; Humans; In Vitro Techniques; Inositol Phosphates; Ligands; Losartan; Protein Binding; Receptors, Angiotensin; Tetrazoles; Time Factors; Transfection

1999
Angiotensin II inhibits interleukin-1 beta-induced nitric oxide production in cultured rat mesangial cells.
    Kidney international, 1999, Volume: 55, Issue:4

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antibodies; Benzimidazoles; Biphenyl Compounds; Blotting, Northern; Cells, Cultured; Gene Expression; Glomerular Mesangium; Imidazoles; Interleukin-1; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetrazoles; Transforming Growth Factor beta

1999
Role of angiotensin in cardioprotective effect of ischemic preconditioning.
    Journal of cardiovascular pharmacology, 1999, Volume: 33, Issue:5

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Coronary Circulation; Creatine Kinase; Female; Heart Rate; Imidazoles; In Vitro Techniques; Ischemic Preconditioning, Myocardial; L-Lactate Dehydrogenase; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Pyridines; Rats; Rats, Wistar; Tetrazoles

1999
Production of angiotensin II by homogeneous cultures of vascular smooth muscle cells from spontaneously hypertensive rats.
    Arteriosclerosis, thrombosis, and vascular biology, 1999, Volume: 19, Issue:5

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aspartic Acid Endopeptidases; Benzimidazoles; Biphenyl Compounds; Cathepsin D; Cathepsin E; Cell Division; Cells, Cultured; Culture Media, Conditioned; Hyperplasia; Hypertension; Hypertrophy; Indans; Kallikreins; Male; Muscle, Smooth, Vascular; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin; Renin-Angiotensin System; RNA, Messenger; Tetrazoles; Tissue Kallikreins

1999
Mechanistic differences of various AT1-receptor blockers in isolated vessels of different origin.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 33, Issue:6

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blood Proteins; Female; Humans; Imidazoles; In Vitro Techniques; Irbesartan; Kinetics; Losartan; Male; Muscle Contraction; Muscle, Smooth, Vascular; Portal Vein; Rabbits; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles

1999
Insurmountable angiotensin AT1 receptor antagonists: the role of tight antagonist binding.
    European journal of pharmacology, 1999, May-14, Volume: 372, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Binding, Competitive; Biphenyl Compounds; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Humans; Imidazoles; Irbesartan; Losartan; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Recombinant Proteins; Tetrazoles

1999
The angiotensin II AT1-receptor antagonist candesartan improves functional recovery and reduces the no-reflow area in reperfused ischemic rat hearts.
    Journal of cardiovascular pharmacology, 1999, Volume: 34, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Coronary Vessels; Heart; In Vitro Techniques; Male; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tetrazoles

1999
Action of AT1 receptor antagonists on angiotensin II-induced tone in human isolated subcutaneous resistance arteries.
    British journal of pharmacology, 1999, Volume: 127, Issue:8

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Arteries; Benzimidazoles; Biphenyl Compounds; Endothelium, Vascular; Humans; Imidazoles; Losartan; Muscle Tonus; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Vasoconstrictor Agents

1999
Alternative angiotensin II formation in rat arteries occurs only at very high concentrations of angiotensin I.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 34, Issue:3

    Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta; Arteries; Benzimidazoles; Biphenyl Compounds; Carotid Arteries; Cricetinae; Male; Mesocricetus; Pressoreceptors; Rats; Rats, Inbred WKY; Serine Proteinase Inhibitors; Tetrazoles; Time Factors; Vasoconstriction

1999
Angiotensin converting enzyme inhibitors block mitogenic signalling pathways in rat cardiac fibroblasts.
    Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 359, Issue:5

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Benzimidazoles; Biphenyl Compounds; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cells, Cultured; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Activation; Fibroblasts; Flavonoids; Heart; Immunoblotting; Isoquinolines; Phosphorylation; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Signal Transduction; STAT3 Transcription Factor; Tetrahydroisoquinolines; Tetrazoles; Time Factors; Trans-Activators

1999
Effects of the insurmountable angiotensin AT1 receptor antagonist candesartan and the surmountable antagonist losartan on ischemia/reperfusion injury in rat hearts.
    European journal of pharmacology, 1999, Sep-03, Volume: 380, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Creatine Kinase; Dose-Response Relationship, Drug; Heart; Hemodynamics; In Vitro Techniques; Losartan; Male; Myocardial Reperfusion Injury; Norepinephrine; Perfusion; Pressure; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles; Time Factors; Vasoconstriction; Vasoconstrictor Agents

1999
Effect of beta(2)-adrenoceptor activation and angiotensin II on tumour necrosis factor and interleukin 6 gene transcription in the rat renal resident macrophage cells.
    Cytokine, 1999, Volume: 11, Issue:10

    Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Angiotensin II; Animals; Animals, Newborn; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Dose-Response Relationship, Drug; Gene Expression Regulation; Genes, Reporter; Interleukin-6; Kidney; Lipopolysaccharides; Macrophages; Promoter Regions, Genetic; Rats; Rats, Wistar; Receptors, Adrenergic, beta-2; Tetrazoles; Transfection; Tumor Necrosis Factor-alpha

1999
Role of AT(1) receptors and autonomic nervous system in mediating acute pressor responses to ANG II in anesthetized mice.
    The American journal of physiology, 1999, Volume: 277, Issue:5

    Topics: Adrenergic beta-Antagonists; Anesthesia; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Atropine; Autonomic Nervous System; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cardiac Output; Dose-Response Relationship, Drug; Enalaprilat; Heart Rate; Hexamethonium; Imidazoles; Mice; Mice, Inbred Strains; Parasympatholytics; Phentolamine; Propranolol; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Vascular Resistance; Vasoconstrictor Agents

1999
Blockade of the renin angiotensin system in heart failure: the potential place of angiotensin II receptor blockers.
    European heart journal, 2000, Volume: 21, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Heart Failure; Humans; Losartan; Receptors, Angiotensin; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan

2000
Effects of angiotensin II and antagonists on AT(1) receptor expression in mesangial cells.
    European journal of pharmacology, 1999, Nov-19, Volume: 384, Issue:2-3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Dexamethasone; Dose-Response Relationship, Drug; Gene Expression Regulation; Glomerular Mesangium; Imidazoles; Losartan; Male; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Tetrazoles

1999
Development of EIA systems for active-form MAP kinase.
    Journal of immunological methods, 2000, Apr-21, Volume: 238, Issue:1-2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antibody Specificity; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Enzyme Activation; Glomerular Mesangium; Humans; Immunoenzyme Techniques; Male; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; PC12 Cells; Rabbits; Rats; Rats, Wistar; Tetrazoles

2000
Angiotensin-II subtype 2 receptor agonist (CGP-42112) inhibits catecholamine biosynthesis in cultured porcine adrenal medullary chromaffin cells.
    Biochemical and biophysical research communications, 2000, Jun-07, Volume: 272, Issue:2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenal Medulla; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Binding, Competitive; Biphenyl Compounds; Catecholamines; Cells, Cultured; Chromaffin Cells; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Induction; Imidazoles; Oligopeptides; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Swine; Tetrazoles; Tyrosine 3-Monooxygenase

2000
Comparative effects of angiotensin II AT-1-type receptor antagonists in vitro on human platelet activation.
    Journal of cardiovascular pharmacology, 2000, Volume: 35, Issue:6

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adult; Angiotensin II; Angiotensin Receptor Antagonists; Antibodies, Monoclonal; Benzimidazoles; Benzoates; Binding, Competitive; Biphenyl Compounds; Blood Platelets; Dose-Response Relationship, Drug; Humans; Imidazoles; Irbesartan; Losartan; Platelet Activation; Pyridines; Radioligand Assay; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Telmisartan; Tetrazoles; Thromboxane A2; Time Factors; Valine; Valsartan

2000
Angiotensin II antagonist prevents electrical remodeling in atrial fibrillation.
    Circulation, 2000, Jun-06, Volume: 101, Issue:22

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Atrial Fibrillation; Atrial Function; Benzimidazoles; Biphenyl Compounds; Captopril; Dogs; Female; Heart Conduction System; Male; Myocardium; Pacemaker, Artificial; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Sinoatrial Node; Tetrazoles; Time Factors

2000
Roles of ANG II and bradykinin in the renal regional blood flow responses to ACE inhibition in sodium-depleted dogs.
    American journal of physiology. Renal physiology, 2000, Volume: 279, Issue:2

    Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Bradykinin; Diet, Sodium-Restricted; Dogs; Laser-Doppler Flowmetry; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renal Circulation; Sodium; Tetrazoles

2000
ACE inhibition and AT(1) receptor blockers: efficacy and duration in hypertension.
    Heart (British Cardiac Society), 2000, Volume: 84 Suppl 1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Blood Pressure Determination; Circadian Rhythm; Delayed-Action Preparations; Evidence-Based Medicine; Humans; Hypertension; Losartan; Patient Compliance; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles

2000
Comparison of the antihypertensive effects of the new angiotensin II (AT1) receptor antagonist candesartan cilexetil (TCV-116) and the angiotensin converting enzyme inhibitor enalapril in rats.
    Hypertension research : official journal of the Japanese Society of Hypertension, 1996, Volume: 19, Issue:2

    Topics: Administration, Oral; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Bradykinin; Enalapril; Enzyme Activation; Hypertension, Renal; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renal Artery; Surgical Instruments; Tetrazoles; Vasoconstrictor Agents

1996
Angiotensin II activates collagen I gene through a mechanism involving the MAP/ER kinase pathway.
    Hypertension (Dallas, Tex. : 1979), 2000, Volume: 36, Issue:3

    Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Benzimidazoles; Biphenyl Compounds; Collagen; Decorin; Enzyme Activation; Enzyme Inhibitors; Extracellular Matrix Proteins; Flavonoids; Gene Expression Regulation, Enzymologic; Genes, fos; Genetic Markers; Humans; Imidazoles; Kidney; Luciferases; Male; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Proteoglycans; Proto-Oncogene Mas; Pyridines; Tetrazoles; Transcriptional Activation; Transforming Growth Factor beta

2000
Increased gene expression of components of the renin-angiotensin system in glomeruli of genetically hypertensive rats.
    Journal of hypertension, 2000, Volume: 18, Issue:9

    Topics: Albuminuria; Angiotensin II; Angiotensinogen; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blotting, Northern; Fibronectins; Gene Expression; Glomerulosclerosis, Focal Segmental; Hydralazine; Hypertension, Renal; Kidney Glomerulus; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Ribonucleases; RNA, Messenger; Tetrazoles; Transforming Growth Factor beta; Transforming Growth Factor beta1

2000
Angiotensin peptides acting at rostral ventrolateral medulla contribute to hypertension of TGR(mREN2)27 rats.
    Physiological genomics, 2000, Apr-27, Volume: 2, Issue:3

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Genetically Modified; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Heart Rate; Hypertension; Male; Medulla Oblongata; Microinjections; Peptide Fragments; Rats; Rats, Sprague-Dawley; Renin; Tetrazoles

2000
Angiotensin II AT(1) blockade normalizes cerebrovascular autoregulation and reduces cerebral ischemia in spontaneously hypertensive rats.
    Stroke, 2000, Volume: 31, Issue:10

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Binding, Competitive; Biphenyl Compounds; Blood Flow Velocity; Blood Pressure; Brain Edema; Brain Ischemia; Cerebrovascular Circulation; Homeostasis; Hypertension; Infarction, Middle Cerebral Artery; Infusion Pumps, Implantable; Injections, Subcutaneous; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles

2000
Role of the angiotensin AT(1) receptor in rat aortic and cardiac PAI-1 gene expression.
    Arteriosclerosis, thrombosis, and vascular biology, 2000, Volume: 20, Issue:10

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Antihypertensive Agents; Aorta; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Gene Expression; Heart Ventricles; Infusions, Intravenous; Male; Muscle, Smooth, Vascular; Myocardium; Plasminogen Activator Inhibitor 1; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Tetrazoles

2000
Angiotensin II regulates the cell cycle of vascular smooth muscle cells from SHR.
    American journal of hypertension, 2000, Volume: 13, Issue:10

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; CDC2-CDC28 Kinases; Cell Cycle; Cell Cycle Proteins; Cells, Cultured; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; DNA; Flow Cytometry; Male; Microtubule-Associated Proteins; Muscle, Smooth, Vascular; Protein Serine-Threonine Kinases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Tetrazoles; Tumor Suppressor Proteins

2000
Angiotensin II blockade in existing hypovolemia: effects of candesartan in the porcine splanchnic and renal circulation.
    Shock (Augusta, Ga.), 2000, Volume: 14, Issue:4

    Topics: Acid-Base Equilibrium; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Female; Hemodynamics; Hypovolemia; Intestinal Mucosa; Liver Circulation; Male; Microcirculation; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renal Circulation; Splanchnic Circulation; Swine; Tetrazoles

2000
Angiotensin II type 1 receptor antagonists. Why do some of them produce insurmountable inhibition?
    Biochemical pharmacology, 2000, Dec-01, Volume: 60, Issue:11

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Binding Sites; Biphenyl Compounds; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Humans; Irbesartan; Losartan; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Recombinant Proteins; Tetrazoles

2000
Diastolic wall stress and ANG II in cardiac hypertrophy and gene expression induced by volume overload.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 279, Issue:6

    Topics: Adrenomedullin; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blood Volume; Calcium Channel Blockers; Diastole; Dihydropyridines; Gene Expression; Heart Rate; Hypertrophy, Left Ventricular; Male; Nitrobenzenes; Peptides; Piperazines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Stress, Mechanical; Tetrazoles; Vasoconstrictor Agents

2000
Glial angiotensinogen regulates brain angiotensin II receptors in transgenic rats TGR(ASrAOGEN).
    American journal of physiology. Regulatory, integrative and comparative physiology, 2001, Volume: 280, Issue:1

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Antihypertensive Agents; Astrocytes; Autoradiography; Benzimidazoles; Biphenyl Compounds; Blood-Brain Barrier; Brain Chemistry; Diabetes Insipidus; Drinking; Imidazoles; Injections, Intraventricular; Iodine Radioisotopes; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Antisense; Salts; Subfornical Organ; Tetrazoles; Vasoconstrictor Agents

2001
Myocardial ischemia activates the JAK-STAT pathway through angiotensin II signaling in in vivo myocardium of rats.
    Journal of molecular and cellular cardiology, 2001, Volume: 33, Issue:2

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blotting, Western; Coronary Vessels; DNA; DNA-Binding Proteins; Drosophila Proteins; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; Guanine Nucleotide Exchange Factors; Imidazoles; Imidazolidines; Immunoblotting; Janus Kinase 1; Janus Kinase 2; Male; Myocardial Infarction; Myocardial Ischemia; Peptidyl-Dipeptidase A; Phosphorylation; Precipitin Tests; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Signal Transduction; STAT1 Transcription Factor; STAT3 Transcription Factor; Tetrazoles; Time Factors; Trans-Activators

2001
A two-state receptor model for the interaction between angiotensin II type 1 receptors and non-peptide antagonists.
    Biochemical pharmacology, 2001, Feb-01, Volume: 61, Issue:3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; CHO Cells; Computer Simulation; Cricetinae; Dose-Response Relationship, Drug; Inositol Phosphates; Irbesartan; Kinetics; Losartan; Models, Biological; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles

2001
Angiotensin II binding sites in the heart of Scyliorhinus canicula: an autoradiographic study.
    General and comparative endocrinology, 2001, Volume: 121, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Benzimidazoles; Binding Sites; Biphenyl Compounds; Dogfish; Endocardium; Heart Atria; Iodine Radioisotopes; Myocardium; Oligopeptides; Receptors, Angiotensin; Tetrazoles

2001
The mechanism of action of angiotensin II is dependent on direct activation of vascular smooth muscle carbonic anhydrase I.
    International journal of clinical & laboratory research, 2000, Volume: 30, Issue:3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Carbonic Anhydrases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Erythrocytes; Female; Humans; In Vitro Techniques; Irbesartan; Male; Middle Aged; Muscle, Smooth, Vascular; Tetrazoles

2000
Alterations of the renin-angiotensin system at the RVLM of transgenic rats with low brain angiotensinogen.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2001, Volume: 280, Issue:2

    Topics: Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Brain; Functional Laterality; Heart Rate; Male; Medulla Oblongata; Microinjections; Peptide Fragments; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Tetrazoles

2001
Effects of angiotensin IV and angiotensin-(1-7) on basal and angiotensin II-stimulated cytosolic Ca2+ in mesangial cells.
    European journal of pharmacology, 2001, Mar-02, Volume: 414, Issue:2-3

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Calcium; Cell Culture Techniques; Cytosol; Dose-Response Relationship, Drug; Glomerular Mesangium; Inositol Phosphates; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Vasoconstrictor Agents

2001
Can angiotensin II receptor blockers be used in patients who have developed a cough or angioedema as a result of taking an ACE inhibitor?
    Cleveland Clinic journal of medicine, 2001, Volume: 68, Issue:3

    Topics: Acrylates; Angioedema; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Black or African American; Clinical Trials as Topic; Cough; Female; Humans; Imidazoles; Irbesartan; Losartan; Male; Randomized Controlled Trials as Topic; Sex Factors; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan

2001
Tight binding of the angiotensin AT(1) receptor antagonist.
    Biochemical pharmacology, 2001, May-15, Volume: 61, Issue:10

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biological Transport; Biphenyl Compounds; Cell Membrane; CHO Cells; Cricetinae; Endocytosis; Gene Deletion; Inositol Phosphates; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Thymidine; Tritium

2001
Effects of blockade of the renin-angiotensin system on tissue factor and plasminogen activator inhibitor-1 synthesis in human cultured monocytes.
    Journal of hypertension, 2001, Volume: 19, Issue:4

    Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Captopril; Cells, Cultured; Culture Media; Humans; Monocytes; Peptidyl-Dipeptidase A; Plasminogen Activator Inhibitor 1; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System; RNA, Messenger; Tetrazoles; Thromboplastin; Tumor Necrosis Factor-alpha

2001
Endogenous angiotensin II in the NTS contributes to sympathetic activation in rats with aortocaval shunt.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2001, Volume: 280, Issue:6

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Arteriovenous Shunt, Surgical; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Echocardiography; Heart Rate; Hemodynamics; Imidazoles; Kidney; Male; Microinjections; Pyridines; Rats; Rats, Inbred WKY; Solitary Nucleus; Sympathetic Nervous System; Tetrazoles; Venae Cavae

2001
Angiotensin II and its metabolites stimulate PAI-1 protein release from human adipocytes in primary culture.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:5

    Topics: Adipose Tissue; Adolescent; Adult; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Female; Humans; Middle Aged; Plasminogen Activator Inhibitor 1; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Valine; Valsartan

2001
Combined effects of AT(1) and ET(A) receptor antagonists, candesartan, and A-127722 in DOCA-salt hypertensive rats.
    General pharmacology, 2000, Volume: 34, Issue:5

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Atrasentan; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Body Weight; Desoxycorticosterone; Disease Models, Animal; Drug Therapy, Combination; Endothelin Receptor Antagonists; Endothelin-1; Hypertension; Kidney; Male; Natriuresis; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles

2000
Protective effect of agiotensin II type I receptor antagonist, CV-11974, on ischemia and reperfusion injury of the liver.
    Transplantation, 2001, Apr-27, Volume: 71, Issue:8

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aspartate Aminotransferases; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Dogs; Female; Hemodynamics; Hepatic Veins; Ischemia; Liver; Liver Circulation; Liver Function Tests; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Regional Blood Flow; Renin; Reperfusion Injury; Tetrazoles; Time Factors

2001
Mildly oxidized low-density lipoprotein acts synergistically with angiotensin II in inducing vascular smooth muscle cell proliferation.
    Journal of hypertension, 2001, Volume: 19, Issue:6

    Topics: Acetylcysteine; Aldehydes; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antioxidants; Benzimidazoles; Biphenyl Compounds; Cardiovascular Diseases; Cell Division; Cells, Cultured; DNA; Drug Synergism; Flavonoids; Humans; Hydrogen Peroxide; Lipoproteins, LDL; Lysophosphatidylcholines; Muscle, Smooth, Vascular; Probucol; Rabbits; Receptor, Angiotensin, Type 1; Tetrazoles; Tyrphostins

2001
Activation of angiotensin II subtype 2 receptor induces catecholamine release in an extracellular Ca(2+)-dependent manner through a decrease of cyclic guanosine 3',5'-monophosphate production in cultured porcine adrenal medullary chromaffin Cells.
    Endocrinology, 2001, Volume: 142, Issue:7

    Topics: Adrenal Medulla; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Calcium; Catecholamines; Cells, Cultured; Chromaffin Cells; Cyclic GMP; Extracellular Space; Imidazoles; Inositol 1,4,5-Trisphosphate; Intracellular Membranes; Oligopeptides; Pyridines; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Swine; Tetrazoles; Virulence Factors, Bordetella

2001
Role of nNOS in regulation of renal function in angiotensin II-induced hypertension.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 38, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Citrulline; Enzyme Inhibitors; Glomerular Filtration Rate; Hypertension, Renal; Kidney; Male; Natriuresis; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renal Plasma Flow; Tetrazoles; Thiourea

2001
Mechanism of action of angiotensin II in human isolated subcutaneous resistance arteries.
    British journal of pharmacology, 2001, Volume: 134, Issue:1

    Topics: Amlodipine; Angiotensin II; Arteries; Benzimidazoles; Biphenyl Compounds; Calcium; Calcium Channel Blockers; Dihydropyridines; Dose-Response Relationship, Drug; Flavonoids; Genistein; Humans; In Vitro Techniques; Nickel; Norepinephrine; Potassium; Ryanodine; Skin; Tetrazoles; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents

2001
Angiotensin-II type 1 receptor interaction is a major regulator for liver fibrosis development in rats.
    Hepatology (Baltimore, Md.), 2001, Volume: 34, Issue:4 Pt 1

    Topics: Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Endothelial Growth Factors; Immunohistochemistry; Liver Cirrhosis, Experimental; Lymphokines; Male; Perindopril; Rats; Rats, Inbred F344; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System; RNA, Messenger; Tetrazoles; Transforming Growth Factor beta; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2001
Angiotensin II induces circadian gene expression of clock genes in cultured vascular smooth muscle cells.
    Circulation, 2001, Oct-09, Volume: 104, Issue:15

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; ARNTL Transcription Factors; Basic Helix-Loop-Helix Transcription Factors; Benzimidazoles; Biological Clocks; Biomarkers; Biphenyl Compounds; Blotting, Northern; Cell Cycle Proteins; Cells, Cultured; Circadian Rhythm; DNA-Binding Proteins; Gene Expression; Imidazoles; Male; Mice; Mice, Inbred BALB C; Muscle, Smooth, Vascular; Nuclear Proteins; Period Circadian Proteins; Pyridines; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Tetrazoles; Transcription Factors

2001
Effects of all-trans retinoic acid on renin-angiotensin system in rats with experimental nephritis.
    American journal of physiology. Renal physiology, 2001, Volume: 281, Issue:5

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Antibodies; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Kidney; Kidney Glomerulus; Male; Nephritis; Peptidyl-Dipeptidase A; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Mineralocorticoid; Renin; Renin-Angiotensin System; RNA, Messenger; Tetrazoles; Thy-1 Antigens; Tretinoin

2001
Angiotensin subtype-2 receptor (AT2 ) negatively regulates subtype-1 receptor (AT1 ) in signal transduction pathways in cultured porcine adrenal medullary chromaffin cells.
    Journal of hypertension, 2001, Volume: 19, Issue:11

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Chromaffin Cells; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; DNA-Binding Proteins; Drug Combinations; Enzyme Activation; Imidazoles; Isoenzymes; Milk Proteins; Mitogen-Activated Protein Kinases; Protein Kinase C; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Signal Transduction; STAT1 Transcription Factor; STAT3 Transcription Factor; STAT5 Transcription Factor; Swine; Tetrazoles; Trans-Activators

2001
Inhibition of facilitation of sympathetic neurotransmission and angiotensin II-induced pressor effects in the pithed rat: comparison between valsartan, candesartan, eprosartan and embusartan.
    Journal of hypertension, 2001, Volume: 19, Issue:12

    Topics: Acrylates; Adrenergic alpha-Agonists; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Decerebrate State; Dihydropyridines; Dose-Response Relationship, Drug; Imidazoles; Male; Norepinephrine; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Sympathetic Nervous System; Synaptic Transmission; Tetrazoles; Thiophenes; Valine; Valsartan

2001
Angiotensin II directly stimulates macula densa Na-2Cl-K cotransport via apical AT(1) receptors.
    American journal of physiology. Renal physiology, 2002, Volume: 282, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biological Transport; Biphenyl Compounds; Cytosol; Diuretics; Furosemide; Imidazoles; Kidney Glomerulus; Microscopy, Fluorescence; Pyridines; Rabbits; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Sodium; Sodium Chloride; Sodium-Potassium-Chloride Symporters; Tetrazoles; Vasoconstrictor Agents

2002
Dilatation of cerebral parenchymal vessels mediated by angiotensin type 1 receptor in cats.
    Neuroscience letters, 2002, Jan-25, Volume: 318, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cats; Cerebral Arteries; Cerebral Cortex; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Female; Imidazoles; Male; Microcirculation; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Vasodilation

2002
Ang II accumulation in rat renal endosomes during Ang II-induced hypertension: role of AT(1) receptor.
    Hypertension (Dallas, Tex. : 1979), 2002, Volume: 39, Issue:1

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antibodies; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Dextrans; Endosomes; Flow Cytometry; Fluoresceins; Hypertension; Kidney; Male; Microvilli; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Renin; Systole; Tetrazoles

2002
Angiotensin II type 2 receptor counter-regulates type 1 receptor in catecholamine synthesis in cultured porcine adrenal medullary chromaffin cells.
    Hypertension (Dallas, Tex. : 1979), 2002, Volume: 39, Issue:1

    Topics: Adrenal Medulla; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Catecholamines; Cells, Cultured; Cyclic GMP; Imidazoles; Phosphodiesterase Inhibitors; Protein Kinase C; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Swine; Tetrazoles; Tyrosine 3-Monooxygenase

2002
Angiotensin I-converting enzyme inhibition increases cardiac catecholamine content and reduces monoamine oxidase activity via an angiotensin type 1 receptor-mediated mechanism.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 300, Issue:2

    Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Brain Chemistry; Catecholamines; Heart; Hemodynamics; In Vitro Techniques; Kinetics; Liver; Male; Mitochondria; Mitochondria, Liver; Monoamine Oxidase; Myocardium; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Tetrazoles

2002
Direct left ventricular wall stretch activates GATA4 binding in perfused rat heart: involvement of autocrine/paracrine pathways.
    Pflugers Archiv : European journal of physiology, 2002, Volume: 443, Issue:3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Autocrine Communication; Benzimidazoles; Biphenyl Compounds; Bosentan; Catheterization; DNA-Binding Proteins; Endothelin Receptor Antagonists; Endothelin-1; GATA4 Transcription Factor; In Vitro Techniques; Male; Myocardium; Paracrine Communication; Perfusion; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Sulfonamides; Tetrazoles; Transcription Factor AP-1; Transcription Factors; Ventricular Function

2002
Salt intake and non-ACE pathways for intrarenal angiotensin II generation in man.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2001, Volume: 2, Issue:1

    Topics: Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Captopril; Diet, Sodium-Restricted; Female; Hemodynamics; Humans; Kidney; Male; Middle Aged; Renal Circulation; Tetrazoles

2001
Valsartan and candesartan can inhibit deteriorating effects of angiotensin II on coronary endothelial function.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2001, Volume: 2, Issue:2

    Topics: Angiotensin II; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Collagenases; Coronary Vessels; Endothelins; Endothelium, Vascular; Enzyme Precursors; Humans; Male; Matrix Metalloproteinase 1; Plasminogen Activator Inhibitor 1; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents

2001
Volume expansion during acute angiotensin II receptor (AT(1)) blockade and NOS inhibition in conscious dogs.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2002, Volume: 282, Issue:4

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blood Proteins; Blood Volume; Consciousness; Dogs; Enzyme Inhibitors; Female; Glomerular Filtration Rate; Heart Rate; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Osmolar Concentration; Potassium; Receptor, Angiotensin, Type 1; Sodium; Tetrazoles

2002
Aortic blood flow subtraction: an alternative method for measuring total renal blood flow in conscious dogs.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2002, Volume: 282, Issue:5

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta, Abdominal; Arterial Occlusive Diseases; Benzimidazoles; Biphenyl Compounds; Blood Flow Velocity; Blood Pressure; Carotid Arteries; Dogs; Endothelin-1; Female; Homeostasis; Regional Blood Flow; Renal Artery; Renal Circulation; Reproducibility of Results; Rheology; Subtraction Technique; Tetrazoles; Ultrasonography; Vascular Resistance; Vasoconstrictor Agents

2002
Angiotensin II directly stimulates ENaC activity in the cortical collecting duct via AT(1) receptors.
    Journal of the American Society of Nephrology : JASN, 2002, Volume: 13, Issue:5

    Topics: Amiloride; Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Benzofurans; Biphenyl Compounds; Hydrogen-Ion Concentration; Intracellular Membranes; Ionophores; Kidney Tubules, Collecting; Losartan; Mice; Microscopy, Fluorescence; Monensin; Rabbits; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Signal Transduction; Sodium Chloride; Tetrazoles

2002
Involvement of Rho-kinase pathway for angiotensin II-induced plasminogen activator inhibitor-1 gene expression and cardiovascular remodeling in hypertensive rats.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 301, Issue:2

    Topics: Amides; Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Body Weight; Hemodynamics; Hypertension; Intracellular Signaling Peptides and Proteins; Male; Mitogen-Activated Protein Kinases; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Organ Size; Plasminogen Activator Inhibitor 1; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-fos; Pyridines; Rats; Rats, Inbred WKY; rho-Associated Kinases; rhoA GTP-Binding Protein; Ribosomal Protein S6 Kinases; RNA, Messenger; Tetrazoles; Ventricular Remodeling

2002
Angiotensin II increases L-type Ca2+ current in gramicidin D-perforated adult rabbit ventricular myocytes: comparison with conventional patch-clamp method.
    Pflugers Archiv : European journal of physiology, 2002, Volume: 444, Issue:1-2

    Topics: Action Potentials; Alkaloids; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Anti-Bacterial Agents; Benzimidazoles; Benzophenanthridines; Biphenyl Compounds; Calcium Channels, L-Type; Cell Separation; Electrophysiology; Enzyme Inhibitors; Gramicidin; Guanidines; Heart; Heart Ventricles; In Vitro Techniques; Male; Myocardium; Patch-Clamp Techniques; Phenanthridines; Protein Kinase C; Rabbits; Receptor, Angiotensin, Type 1; Sodium-Hydrogen Exchangers; Sulfones; Tetrazoles

2002
Comparison of nitric oxide production in response to carbachol between macrovascular and microvascular cardiac endothelial cells.
    Circulation journal : official journal of the Japanese Circulation Society, 2002, Volume: 66, Issue:5

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Captopril; Carbachol; Cells, Cultured; Coronary Circulation; Endothelium, Vascular; Male; Microcirculation; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Muscarinic M3; Receptors, Angiotensin; Receptors, Muscarinic; Tetrazoles; Type C Phospholipases

2002
Angiotensin II angiogenic effect in vivo involves vascular endothelial growth factor- and inflammation-related pathways.
    Laboratory investigation; a journal of technical methods and pathology, 2002, Volume: 82, Issue:6

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antibodies, Monoclonal; Benzimidazoles; Biphenyl Compounds; Collagen; Cyclooxygenase 2; Disease Models, Animal; Drug Combinations; Drug Therapy, Combination; Endothelial Growth Factors; Female; Imidazoles; Isoenzymes; Laminin; Lymphokines; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Pathologic; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Prostaglandin-Endoperoxide Synthases; Proteoglycans; Pyridines; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Sulfonamides; Tetrazoles; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2002
Peripherally applied candesartan inhibits central responses to angiotensin II in conscious rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 2002, Volume: 365, Issue:6

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arginine Vasopressin; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Drinking; Male; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Tetrazoles; Wakefulness

2002
Prejunctional and postjunctional inhibitory actions of eprosartan and candesartan in the isolated rabbit mesenteric artery.
    Journal of cardiovascular pharmacology, 2002, Volume: 40, Issue:1

    Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Dose-Response Relationship, Drug; Female; Imidazoles; In Vitro Techniques; Male; Mesenteric Arteries; Rabbits; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Receptors, Presynaptic; Tetrazoles; Thiophenes

2002
Neurohormonal influences on maintenance and reversal of two-kidney one-clip renal hypertension.
    Acta physiologica Scandinavica, 2002, Volume: 175, Issue:3

    Topics: Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Catecholamines; Heart Rate; Hypertension, Renovascular; Kidney; Male; Neurotransmitter Agents; Phentolamine; Propranolol; Rats; Rats, Wistar; Reference Values; Renal Circulation; Renin; Renin-Angiotensin System; Sympathetic Nervous System; Tetrazoles

2002
Influence of angiotensin II type 1-receptor antagonist CV11974 on infarct size and adjacent regional function after ischemia-reperfusion in dogs.
    Japanese journal of pharmacology, 2002, Volume: 89, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Dogs; Hemodynamics; Myocardial Infarction; Receptors, Angiotensin; Reperfusion Injury; Tetrazoles; Ventricular Function, Left

2002
Role of angiotensin II and angiotensin II receptors in vascular smooth muscle cell migration in vitro.
    Chinese medical journal, 2002, Volume: 115, Issue:5

    Topics: Actins; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Cell Movement; Cells, Cultured; Cytoskeleton; Dose-Response Relationship, Drug; Female; Focal Adhesions; Imidazoles; Immunohistochemistry; Male; Muscle, Smooth, Vascular; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Tetrazoles

2002
AT1 receptor blockade reduces cardiac calcineurin activity in hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcineurin; Cardiomegaly; Echocardiography; Fibrosis; Gene Expression Regulation; Hypertension; Male; Myocardium; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; RNA, Messenger; Stress, Mechanical; Tacrolimus; Tetrazoles; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1

2002
In vitro and in vivo characterization of the activity of telmisartan: an insurmountable angiotensin II receptor antagonist.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 302, Issue:3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Cell Membrane; In Vitro Techniques; Irbesartan; Kinetics; Muscle, Smooth, Vascular; Radioligand Assay; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Telmisartan; Tetrazoles

2002
Antagonist interaction with endogenous AT(1) receptors in human cell lines.
    Biochemical pharmacology, 2002, Oct-15, Volume: 64, Issue:8

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Binding, Competitive; Biphenyl Compounds; Cell Line; CHO Cells; Cricetinae; Humans; Inositol Phosphates; Iodine Radioisotopes; Irbesartan; Muscle, Smooth, Vascular; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Tetrazoles; Transfection

2002
Role of ANG II in coronary capillary angiogenesis at the insulin-resistant stage of a NIDDM rat model.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 283, Issue:4

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Capillaries; Coronary Circulation; Diabetes Mellitus, Type 2; Disease Models, Animal; Endothelial Growth Factors; Extracellular Matrix Proteins; Gene Expression; Glycation End Products, Advanced; Hypoxia-Inducible Factor 1, alpha Subunit; Insulin Resistance; Lymphokines; Male; Neovascularization, Physiologic; Rats; Rats, Inbred OLETF; Rats, Long-Evans; Receptor Protein-Tyrosine Kinases; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; RNA, Messenger; Tetrazoles; Transcription Factors; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2002
Rostral ventrolateral medulla neurons of neonatal Wistar-Kyoto and spontaneously hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:4

    Topics: Action Potentials; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Benzimidazoles; Biphenyl Compounds; Brain Stem; Cells, Cultured; Hypertension; Kinetics; Membrane Potentials; Neurons; Patch-Clamp Techniques; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Spinal Cord; Tetrazoles

2002
Dose-dependent regulation of NAD(P)H oxidase expression by angiotensin II in human endothelial cells: protective effect of angiotensin II type 1 receptor blockade in patients with coronary artery disease.
    Arteriosclerosis, thrombosis, and vascular biology, 2002, Nov-01, Volume: 22, Issue:11

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Coronary Artery Bypass; Coronary Artery Disease; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Imidazoles; Mammary Arteries; Membrane Glycoproteins; NADH, NADPH Oxidoreductases; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Preoperative Care; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System; Retrospective Studies; Superoxides; Tetrazoles; Umbilical Veins

2002
Renal segmental microvascular responses to ANG II in AT1A receptor null mice.
    American journal of physiology. Renal physiology, 2003, Volume: 284, Issue:3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arterioles; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Kidney; Male; Mice; Mice, Knockout; Microcirculation; Nephrons; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Tetrazoles; Vascular Patency; Vascular Resistance

2003
Comparison of the antagonistic effects of different angiotensin II receptor blockers in human coronary arteries.
    European journal of heart failure, 2002, Volume: 4, Issue:6

    Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Base Sequence; Benzimidazoles; Biphenyl Compounds; Coronary Vessels; Culture Techniques; Dose-Response Relationship, Drug; Female; Humans; Imidazoles; Losartan; Male; Middle Aged; Molecular Sequence Data; Probability; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazoles; Valine; Valsartan; Vasoconstriction

2002
Endothelin-1 contributes to the Frank-Starling response in hypertrophic rat hearts.
    Hypertension (Dallas, Tex. : 1979), 2003, Volume: 41, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Animals, Genetically Modified; Benzimidazoles; Biphenyl Compounds; Bosentan; Endothelin Receptor Antagonists; Endothelin-1; Heart Ventricles; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Myocardial Contraction; Organ Culture Techniques; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin; RNA, Messenger; Stress, Mechanical; Sulfonamides; Tetrazoles

2003
Control of dendritic cell differentiation by angiotensin II.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2003, Volume: 17, Issue:3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antibodies; Benzimidazoles; Biphenyl Compounds; Cell Differentiation; Cells, Cultured; Dendritic Cells; Endocytosis; Hematopoietic Stem Cells; Humans; Irbesartan; Losartan; Lymphocyte Activation; Mice; Models, Biological; Monocytes; Phenotype; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles

2003
Binding of KRH-594, an antagonist of the angiotensin II type 1 receptor, to cloned human and rat angiotensin II receptors.
    Fundamental & clinical pharmacology, 2002, Volume: 16, Issue:4

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Chlorocebus aethiops; COS Cells; Dose-Response Relationship, Drug; Humans; Imidazoles; In Vitro Techniques; Liver; Losartan; Membranes; Oligopeptides; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Thiadiazoles; Time Factors; Transfection

2002
Effects of ANG II type 1 and 2 receptors on oxidative stress, renal NADPH oxidase, and SOD expression.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2003, Volume: 285, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Body Weight; Gene Expression Regulation, Enzymologic; Imidazoles; Isoprostanes; Kidney; Male; Malondialdehyde; NADPH Oxidases; Oxidative Stress; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Superoxide Dismutase; Tetrazoles; Vasoconstrictor Agents

2003
Down-regulation of bradykinin B2-receptor mRNA in the heart in pressure-overload cardiac hypertrophy in the rat.
    Biochemical pharmacology, 2003, Mar-15, Volume: 65, Issue:6

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Benzimidazoles; Biphenyl Compounds; Cardiomegaly; Cell Membrane; Down-Regulation; Gene Expression; Heart; Humans; Kallikreins; Kininogens; Male; Myocardium; Rats; Rats, Wistar; Receptor, Bradykinin B2; Receptors, Bradykinin; RNA, Messenger; Tetrazoles; Vasoconstriction

2003
Angiotensin II-induced modulation of endothelium-dependent relaxation in rabbit mesenteric resistance arteries.
    The Journal of physiology, 2003, May-01, Volume: 548, Issue:Pt 3

    Topics: Acetylcholine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Cell Membrane Permeability; Cyclic GMP; Enalaprilat; Endothelium, Vascular; In Vitro Techniques; Kinetics; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Nitroarginine; Rabbits; Receptor, Angiotensin, Type 1; Tetrazoles; Thiazepines; Vasodilation

2003
Functional antagonism of different angiotensin II type I receptor blockers in human arteries.
    Cardiovascular drugs and therapy, 2002, Volume: 16, Issue:4

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Dose-Response Relationship, Drug; Humans; Imidazoles; In Vitro Techniques; Losartan; Mammary Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Receptor, Angiotensin, Type 1; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents

2002
AT1 receptors in the RVLM mediate pressor responses to emotional stress in rabbits.
    Hypertension (Dallas, Tex. : 1979), 2003, Volume: 41, Issue:5

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Baroreflex; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Consciousness; Female; Glutamates; Heart Rate; Hypertension; Kidney; Losartan; Male; Medulla Oblongata; Rabbits; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Stress, Psychological; Sympathetic Nervous System; Tetrazoles

2003
Long-term regulation of ENaC expression in kidney by angiotensin II.
    Hypertension (Dallas, Tex. : 1979), 2003, Volume: 41, Issue:5

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Benzothiadiazines; Bicarbonates; Biphenyl Compounds; Diuretics; Epithelial Sodium Channels; Gene Expression Regulation; Immunoblotting; Infusion Pumps; Injections, Subcutaneous; Kidney; Kidney Cortex; Kidney Medulla; Kidney Tubules, Distal; Male; Mineralocorticoid Receptor Antagonists; Potassium; Protein Subunits; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium Channels; Sodium Chloride Symporter Inhibitors; Sodium Chloride Symporters; Sodium Chloride, Dietary; Spironolactone; Symporters; Tetrazoles; Time Factors

2003
Anti-inflammatory effects of angiotensin II AT1 receptor antagonism prevent stress-induced gastric injury.
    American journal of physiology. Gastrointestinal and liver physiology, 2003, Volume: 285, Issue:2

    Topics: Adrenal Medulla; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arteries; Benzimidazoles; Biphenyl Compounds; Blood Flow Velocity; Cold Temperature; Corticosterone; Dinoprostone; Endothelium, Vascular; Epinephrine; Gastric Mucosa; Intercellular Adhesion Molecule-1; Leukocyte Count; Male; Neutrophils; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Restraint, Physical; RNA, Messenger; Stomach Ulcer; Stress, Physiological; Tetrazoles; Tumor Necrosis Factor-alpha; Tyrosine 3-Monooxygenase

2003
[Angiotensin II antagonist treatment as a contributory cause of acute renal failure].
    Ugeskrift for laeger, 2003, Mar-24, Volume: 165, Issue:13

    Topics: Acute Kidney Injury; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Humans; Male; Middle Aged; Renin-Angiotensin System; Tetrazoles

2003
Intraluminal pressure increases vascular neuronal nitric oxide synthase expression.
    Journal of hypertension, 2003, Volume: 21, Issue:5

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Carotid Artery, Common; Circadian Rhythm; Endothelium, Vascular; Indoles; Isoenzymes; Isometric Contraction; Male; Models, Animal; Models, Cardiovascular; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Tetrazoles; Time Factors; Vasoconstrictor Agents

2003
Angiotensin II inhibits endothelial cell motility through an AT1-dependent oxidant-sensitive decrement of nitric oxide availability.
    Arteriosclerosis, thrombosis, and vascular biology, 2003, Jul-01, Volume: 23, Issue:7

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Cell Division; Cell Movement; Dose-Response Relationship, Drug; Endothelial Cells; Endothelium, Vascular; Glutathione; Humans; NADPH Oxidases; Nitric Oxide; Oxidants; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Tetrazoles; Time Factors

2003
Effect of AT1 receptor blockade on hepatic redox status in SHR: possible relevance for endothelial function?
    American journal of physiology. Regulatory, integrative and comparative physiology, 2003, Volume: 285, Issue:3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Glutathione Reductase; Hypertension; Liver; Malondialdehyde; Membrane Transport Proteins; NADPH Dehydrogenase; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxidation-Reduction; Oxidative Stress; Phosphoproteins; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Tetrazoles

2003
Influence of plasma insulin levels on antinatriuretic and vasoconstrictor actions of angiotensin-II.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2003, Volume: 25, Issue:4

    Topics: Angiotensin II; Animals; Anti-Bacterial Agents; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Diabetes Mellitus, Experimental; Diuresis; Drug Interactions; Enzyme Inhibitors; Ganglionic Blockers; Heart Rate; Hypoglycemic Agents; Insulin; Kidney; Natriuresis; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Sprague-Dawley; Streptozocin; Tetrazoles; Vasoconstrictor Agents

2003
Angiotensin II blockade augments renal cortical microvascular pO2 indicating a novel, potentially renoprotective action.
    Nephron. Physiology, 2003, Volume: 94, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Enalaprilat; Hypertension; Hypoxia; Kidney Cortex; Male; Microcirculation; Oxygen; Oxygen Consumption; Partial Pressure; Pilot Projects; Porphyrins; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Tetrazoles

2003
Endogenous angiotensin affects responses to stimulation of baroreceptor afferent nerves.
    Journal of hypertension, 2003, Volume: 21, Issue:8

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Baroreflex; Benzimidazoles; Biphenyl Compounds; Diet, Sodium-Restricted; Electric Stimulation; Male; Neurons, Afferent; Pressoreceptors; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Sympathetic Nervous System; Tetrazoles; Vagus Nerve

2003
Myogenic constriction is increased in mesenteric resistance arteries from rats with chronic heart failure: instantaneous counteraction by acute AT1 receptor blockade.
    British journal of pharmacology, 2003, Volume: 139, Issue:7

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Bridged Bicyclo Compounds, Heterocyclic; Captopril; Chronic Disease; Coronary Vessels; Disease Models, Animal; Endothelium-Dependent Relaxing Factors; Endothelium, Vascular; Fatty Acids, Unsaturated; Heart; Heart Failure; Hydrazines; Imidazoles; Indomethacin; Lisinopril; Losartan; Male; Mesenteric Arteries; Nitric Oxide; omega-N-Methylarginine; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Superoxide Dismutase; Sympathetic Nervous System; Tetrazoles; Tetrodotoxin; Vascular Resistance

2003
In salt-sensitive hypertension, increased superoxide production is linked to functional upregulation of angiotensin II.
    Hypertension (Dallas, Tex. : 1979), 2003, Volume: 42, Issue:5

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Endothelium, Vascular; Hypertension; Hypertrophy; Hypertrophy, Left Ventricular; Isoprostanes; Proteinuria; Rats; Rats, Inbred Dahl; Sodium Chloride; Superoxides; Tetrazoles; Up-Regulation; Vasodilation

2003
Angiotensin II receptor blockade prevents microangiopathy and preserves diastolic function in the diabetic rat heart.
    Heart (British Cardiac Society), 2003, Volume: 89, Issue:10

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Glucose; Body Weight; Capillaries; Cytokines; Diabetic Angiopathies; Heme Oxygenase (Decyclizing); Immunohistochemistry; Male; Matrix Metalloproteinases; Organ Size; Rats; Rats, Inbred OLETF; Reverse Transcriptase Polymerase Chain Reaction; Tetrazoles; Tissue Inhibitor of Metalloproteinase-2; Ventricular Dysfunction, Left

2003
Angiotensin II type 1 receptor-mediated augmentation of renal interstitial fluid angiotensin II in angiotensin II-induced hypertension.
    Journal of hypertension, 2003, Volume: 21, Issue:10

    Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Body Weight; Extracellular Fluid; Hypertension, Renal; Kidney; Male; Microdialysis; Organ Size; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Tetrazoles; Vasoconstrictor Agents

2003
[Dosage equivalents of AT1-receptor antagonists available in Germany].
    Deutsche medizinische Wochenschrift (1946), 2003, Oct-31, Volume: 128, Issue:44

    Topics: Acrylates; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Clinical Trials as Topic; Germany; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Olmesartan Medoxomil; Placebos; Telmisartan; Tetrazoles; Therapeutic Equivalency; Thiophenes; Time Factors; Valine; Valsartan

2003
ROS during the acute phase of Ang II hypertension participates in cardiovascular MAPK activation but not vasoconstriction.
    Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:1

    Topics: Acute Disease; Adrenergic alpha-Agonists; Angiotensin II; Animals; Antioxidants; Aorta; Benzimidazoles; Biphenyl Compounds; Cyclic N-Oxides; Enzyme Activation; Heart Ventricles; Hemodynamics; Hypertension; Male; Mitogen-Activated Protein Kinases; Oxidative Stress; Phenylephrine; Prazosin; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Spin Labels; Tetrazoles; Thiobarbituric Acid Reactive Substances; Vasoconstrictor Agents

2004
Angiotensin II blockade prevents hyperglycemia-induced activation of JAK and STAT proteins in diabetic rat kidney glomeruli.
    American journal of physiology. Renal physiology, 2004, Volume: 286, Issue:4

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Diabetic Nephropathies; DNA-Binding Proteins; Enzyme Inhibitors; Hyperglycemia; Intracellular Signaling Peptides and Proteins; Janus Kinase 2; Kidney Glomerulus; Male; Milk Proteins; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Signal Transduction; STAT1 Transcription Factor; STAT3 Transcription Factor; STAT5 Transcription Factor; Tetrazoles; Trans-Activators; Transcription, Genetic; Tyrphostins

2004
Pressure-independent effects of angiotensin II on hypertensive myocardial fibrosis.
    Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cell Movement; Constriction; Coronary Vessels; Fibrosis; Hypertension; Hypertrophy, Left Ventricular; Inflammation; Macrophages; Male; Myocardium; Peptidyl-Dipeptidase A; Pressure; Rats; Rats, Wistar; Tetrazoles

2004
Sub-depressor dose of angiotensin type-1 receptor blocker inhibits transforming growth factor-beta-mediated perivascular fibrosis in hypertensive rat hearts.
    Journal of cardiovascular pharmacology, 2003, Volume: 42 Suppl 1

    Topics: Administration, Oral; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Benzimidazoles; Biphenyl Compounds; Collagen; Constriction; Disease Models, Animal; Dose-Response Relationship, Drug; Endomyocardial Fibrosis; Fibroblasts; Hypertension; Male; Myocytes, Cardiac; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Tetrazoles; Time Factors; Transforming Growth Factor beta; Ventricular Remodeling

2003
Cerebral ischemia enhances vascular angiotensin AT1 receptor-mediated contraction in rats.
    Stroke, 2004, Volume: 35, Issue:4

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Brain Ischemia; Culture Techniques; Infarction, Middle Cerebral Artery; Losartan; Male; Middle Cerebral Artery; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; RNA, Messenger; Tetrazoles; Vasoconstriction; Vasoconstrictor Agents

2004
Effect of saponin and filipin on antagonist binding to AT 1 receptors in intact cells.
    Biochemical pharmacology, 2004, Apr-15, Volume: 67, Issue:8

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Binding, Competitive; Biphenyl Compounds; CHO Cells; Cricetinae; Drug Interactions; Female; Filipin; Humans; Kinetics; Radioligand Assay; Receptor, Angiotensin, Type 1; Saponins; Tetrazoles; Transfection

2004
The effects of candesartan and ramipril on adrenal catecholamine release in anaesthetized dogs.
    European journal of pharmacology, 2004, Apr-05, Volume: 489, Issue:1-2

    Topics: Adrenal Glands; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Catecholamines; Chromatography, High Pressure Liquid; Denervation; Dogs; Electric Stimulation; Homeostasis; Male; Ramipril; Stimulation, Chemical; Tetrazoles

2004
Plasma aldosterone concentration in the patient with diabetes mellitus.
    Kidney international, 2004, Volume: 65, Issue:4

    Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Case-Control Studies; Diabetes Mellitus, Type 1; Female; Humans; Male; Middle Aged; Osmolar Concentration; Renin; Tetrazoles

2004
Aldosterone antagonist facilitates the cardioprotective effects of angiotensin receptor blockers in hypertensive rats.
    Journal of hypertension, 2004, Volume: 22, Issue:5

    Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Body Weight; Cardiomegaly; Cardiotonic Agents; Collagen Type I; Collagen Type III; Drug Synergism; Fibrosis; Hypertension; Male; Mineralocorticoid Receptor Antagonists; Myocardium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; RNA, Messenger; Spironolactone; Tetrazoles

2004
Chronic production of angiotensin IV in the brain leads to hypertension that is reversible with an angiotensin II AT1 receptor antagonist.
    Circulation research, 2004, Jun-11, Volume: 94, Issue:11

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Allosteric Regulation; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Brain; Calcium Signaling; CHO Cells; Cricetinae; Cricetulus; Gene Expression; Genes, Synthetic; Glial Fibrillary Acidic Protein; Globins; Humans; Hypertension; Imidazoles; Mice; Mice, Transgenic; Organ Specificity; Protein Sorting Signals; Pyridines; Rabbits; Receptor, Angiotensin, Type 1; Recombinant Fusion Proteins; Renin; Renin-Angiotensin System; Tetrazoles; Transgenes

2004
Plasma and kidney angiotensin II levels and renal functional responses to AT(1) receptor blockade in hypertensive Ren-2 transgenic rats.
    Journal of hypertension, 2004, Volume: 22, Issue:4

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Genetically Modified; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Glomerular Filtration Rate; Hypertension; Kidney Function Tests; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renal Plasma Flow; RNA, Messenger; Sodium; Tetrazoles

2004
Angiotensin II stimulates the release of interleukin-6 and interleukin-8 from cultured human adipocytes by activation of NF-kappaB.
    Arteriosclerosis, thrombosis, and vascular biology, 2004, Volume: 24, Issue:7

    Topics: Adipocytes; Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Electrophoretic Mobility Shift Assay; Female; Humans; Imidazoles; Inflammation; Interleukin-6; Interleukin-8; NF-kappa B; Nitriles; Phosphorylation; Protein Processing, Post-Translational; Protein Transport; Pyridines; Receptor, Angiotensin, Type 1; RNA, Messenger; Sulfones; Tetrazoles; Transcription Factor RelA; Transcriptional Activation

2004
Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II.
    Nature cell biology, 2004, Volume: 6, Issue:6

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Cardiomegaly; COS Cells; Cytosol; GTP-Binding Proteins; Humans; Janus Kinase 2; Mice; Mice, Knockout; Mitogen-Activated Protein Kinases; Muscle Contraction; Myocytes, Cardiac; Phosphatidylinositols; Protein Transport; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Stress, Mechanical; Tetrazoles; Up-Regulation

2004
Pharmacological properties of angiotensin II receptors in cultured rabbit gingival fibroblasts.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2004, Volume: 137, Issue:3

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Binding, Competitive; Biphenyl Compounds; Blotting, Western; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Fibroblasts; Gingiva; Kinetics; Losartan; Rabbits; Radioligand Assay; Receptors, Angiotensin; Saralasin; Tetrazoles; Tritium

2004
Angiotensin II AT1 receptor blockade decreases brain artery inflammation in a stress-prone rat strain.
    Annals of the New York Academy of Sciences, 2004, Volume: 1018

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arteritis; Benzimidazoles; Biphenyl Compounds; Brain; Cell Adhesion; Intercellular Adhesion Molecule-1; Macrophages; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Stress, Physiological; Tetrazoles

2004
Effects of angiotensin II type 1 receptor antagonist on pressor responses to pulsatile compression of the rostral ventrolateral medulla in rats.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2004, Volume: 27, Issue:6

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Excitatory Amino Acid Antagonists; Glutamic Acid; Hypertension; Imidazoles; Injections, Intravenous; Kynurenic Acid; Male; Medulla Oblongata; Pulsatile Flow; Pyridines; Rats; Rats, Wistar; Sympathetic Nervous System; Tetrazoles; Vasoconstrictor Agents

2004
Regulation of renal proximal fluid uptake by luminal and peritubular angiotensin II.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2004, Volume: 5, Issue:2

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Benzimidazoles; Biological Transport; Biphenyl Compounds; Capillaries; Kidney Tubules, Proximal; Male; Rats; Rats, Wistar; Tetrazoles; Vasoconstrictor Agents

2004
Metabolism of angiotensin II is required for its in vivo effect on dopamine release in the striatum of the rat.
    Journal of neurochemistry, 2004, Volume: 90, Issue:5

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Hemoglobins; Imidazoles; Male; Methionine; Microdialysis; Naltrexone; Narcotic Antagonists; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Sulfonic Acids; Tetrazoles; Time Factors

2004
Endogenous angiotensin II in the regulation of hypoxic pulmonary vasoconstriction in anaesthetized dogs.
    Critical care (London, England), 2004, Volume: 8, Issue:4

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Dogs; Enalaprilat; Endothelium, Vascular; Hypertension, Pulmonary; Hypoxia; Lung; Models, Animal; Renin-Angiotensin System; Tetrazoles; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents

2004
Extracellular signal regulated kinase and SMAD signaling both mediate the angiotensin II driven progression towards overt heart failure in homozygous TGR(mRen2)27.
    Journal of molecular medicine (Berlin, Germany), 2004, Volume: 82, Issue:10

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Genetically Modified; Atrial Natriuretic Factor; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Collagen Type I; Disease Models, Animal; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; Fibrosis; Heart Failure; Homozygote; Hypertrophy, Left Ventricular; Imidazoles; Immunohistochemistry; Male; Mitogen-Activated Protein Kinases; Myocardium; Protein-Tyrosine Kinases; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renin; Smad Proteins; Tetrazoles; Time Factors; Trans-Activators; Tyrphostins

2004
Oral administration of an AT1 receptor antagonist prevents the central effects of angiotensin II in spontaneously hypertensive rats.
    Brain research, 2004, Nov-26, Volume: 1028, Issue:1

    Topics: Administration, Oral; Adrenal Glands; Adrenocorticotropic Hormone; Analysis of Variance; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Catechols; Corticosterone; Drug Administration Schedule; Drug Interactions; Injections, Intraventricular; Locus Coeruleus; Male; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; RNA, Messenger; Tetrazoles; Tyrosine 3-Monooxygenase

2004
Transforming growth factor beta receptor endoglin is expressed in cardiac fibroblasts and modulates profibrogenic actions of angiotensin II.
    Circulation research, 2004, Dec-10, Volume: 95, Issue:12

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Antibodies, Monoclonal; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Collagen Type I; Endoglin; Fibroblasts; Flavonoids; Gene Expression Regulation; Imidazoles; Intracellular Signaling Peptides and Proteins; Losartan; MAP Kinase Signaling System; Matrix Metalloproteinase 1; Myocardium; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Transforming Growth Factor beta; RNA, Messenger; Signal Transduction; Tetrazoles; Valine; Valsartan

2004
Hepatocyte growth factor induces an endothelin-mediated decline in glomerular filtration rate.
    American journal of physiology. Renal physiology, 2005, Volume: 288, Issue:1

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Bosentan; Cattle; Cells, Cultured; Drug Administration Schedule; Endothelin-1; Glomerular Filtration Rate; Hepatocyte Growth Factor; Kidney; Kidney Glomerulus; Male; Rats; Rats, Sprague-Dawley; Sulfonamides; Tetrazoles

2005
Renal angiotensin II type-2 receptors are upregulated and mediate the candesartan-induced natriuresis/diuresis in obese Zucker rats.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 45, Issue:2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Diuresis; Imidazoles; Kidney; Male; Natriuresis; Obesity; Oligopeptides; Pyridines; Rats; Rats, Zucker; Receptor, Angiotensin, Type 2; Tetrazoles; Up-Regulation

2005
Combination therapy with an angiotensin-converting enzyme inhibitor and an angiotensin II receptor blocker synergistically suppresses chronic pancreatitis in rats.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 313, Issue:1

    Topics: Actins; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Body Weight; Chronic Disease; Cytokines; Dose-Response Relationship, Drug; Drug Synergism; Fibrosis; Genes, ras; Hydroxyproline; Immunohistochemistry; Lisinopril; Male; Organ Size; Pancreatitis; Peptidyl-Dipeptidase A; Peroxidase; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; RNA, Messenger; Tetrazoles

2005
The renal vascular response to ANG II injection is reduced in the nonclipped kidney of two-kidney, one-clip hypertension.
    American journal of physiology. Renal physiology, 2005, Volume: 289, Issue:2

    Topics: Angiotensin II; Animals; Arginine Vasopressin; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blotting, Western; Cyclooxygenase Inhibitors; Down-Regulation; Hemodynamics; Hypertension, Renovascular; Indomethacin; Male; Organ Size; Proteins; Rats; Receptors, Angiotensin; Renal Circulation; Renin; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Tetrazoles; Vascular Resistance; Vasoconstrictor Agents

2005
Functional expression of the angiotensin II type 1 receptor in human ovarian carcinoma cells and its blockade therapy resulting in suppression of tumor invasion, angiogenesis, and peritoneal dissemination.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Apr-01, Volume: 11, Issue:7

    Topics: Adenocarcinoma; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antigens, CD34; Benzimidazoles; Biphenyl Compounds; Cell Line, Tumor; Dose-Response Relationship, Drug; Female; Humans; Immunohistochemistry; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neovascularization, Pathologic; Ovarian Neoplasms; Peritoneum; Receptor, Angiotensin, Type 1; Tetrazoles; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays

2005
Critical role of angiotensin II in excess salt-induced brain oxidative stress of stroke-prone spontaneously hypertensive rats.
    Stroke, 2005, Volume: 36, Issue:5

    Topics: Amlodipine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blood-Brain Barrier; Calcium Channel Blockers; Cell Proliferation; Cerebral Arteries; Cerebral Cortex; Disease Models, Animal; Hippocampus; Hypertensive Encephalopathy; Male; Neurons; Oxidative Stress; Rats; Rats, Inbred SHR; Sodium Chloride; Stroke; Superoxides; Tetrazoles

2005
Candesartan prevents angiotensin II-induced facilitation of hypoxic neuronal damage through PKCdelta inhibition.
    Brain research. Molecular brain research, 2005, Apr-27, Volume: 135, Issue:1-2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blotting, Western; Cell Death; Cell Hypoxia; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression Regulation; Imidazoles; In Situ Nick-End Labeling; Mice; PC12 Cells; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Pyridines; Rats; Serine; Tetrazoles; Time Factors; Transfection

2005
Ligand binding and functional properties of human angiotensin AT1 receptors in transiently and stably expressed CHO-K1 cells.
    European journal of pharmacology, 2005, Apr-18, Volume: 513, Issue:1-2

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Binding, Competitive; Biphenyl Compounds; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Gene Expression; Green Fluorescent Proteins; Humans; Inositol Phosphates; Kinetics; Ligands; Microscopy, Confocal; Radioligand Assay; Receptor, Angiotensin, Type 1; Recombinant Fusion Proteins; Tetrazoles; Transfection; Tritium

2005
ATR blockade reduces IFN-gamma production in lymphocytes in vivo and in vitro.
    Kidney international, 2005, Volume: 67, Issue:6

    Topics: Adult; Aged; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Female; Humans; Interferon-gamma; Losartan; Lymphocyte Activation; Lymphocytes; Male; Middle Aged; Polymerase Chain Reaction; RNA, Messenger; Tetrazoles

2005
Angiotensin II and nitric oxide in neural control of intrarenal blood flow.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2005, Volume: 289, Issue:3

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Kidney Cortex; Laser-Doppler Flowmetry; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rabbits; Receptor, Angiotensin, Type 1; Renal Circulation; Sympathetic Nervous System; Tetrazoles

2005
Calcium and chloride channel activation by angiotensin II-AT1 receptors in preglomerular vascular smooth muscle cells.
    American journal of physiology. Renal physiology, 2005, Volume: 289, Issue:4

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Calcium; Calcium Channel Blockers; Calcium Channels; Calibration; Capillaries; Cell Separation; Chloride Channels; Diltiazem; Gallic Acid; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Male; Muscle, Smooth, Vascular; ortho-Aminobenzoates; Potassium Chloride; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Tetrazoles; Vasoconstrictor Agents

2005
Angiotensin II promotes leptin production in cultured human fat cells by an ERK1/2-dependent pathway.
    Obesity research, 2005, Volume: 13, Issue:6

    Topics: Adipocytes; Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Blotting, Western; Butadienes; Cells, Cultured; Chromans; Drug Interactions; Extracellular Signal-Regulated MAP Kinases; Female; Fibrinolytic Agents; Humans; Leptin; MAP Kinase Signaling System; Nitriles; Protein Kinase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazoles; Thiazolidinediones; Troglitazone

2005
Electrophysiological properties of rostral ventrolateral medulla neurons in angiotensin II 1a receptor knockout mice.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 46, Issue:2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Electrophysiology; Imidazoles; Medulla Oblongata; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pyridines; Receptor, Angiotensin, Type 1; Tetrazoles

2005
The role of intrarenal angiotensin II in the development of hypertension in Ren-2 transgenic rats.
    Journal of hypertension, 2005, Volume: 23, Issue:8

    Topics: Angiotensin II; Animals; Animals, Genetically Modified; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blotting, Western; Hypertension; Kidney; Proteins; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Renal Circulation; Sodium; Tetrazoles

2005
Enhanced tubuloglomerular feedback in Cyp1a1-Ren2 transgenic rats with inducible ANG II-dependent malignant hypertension.
    American journal of physiology. Renal physiology, 2005, Volume: 289, Issue:6

    Topics: Angiotensin II; Animals; Animals, Genetically Modified; Benzimidazoles; Biphenyl Compounds; Cytochrome P-450 CYP1A1; Feedback; Glomerular Filtration Rate; Hypertension, Malignant; Indoles; Kidney Glomerulus; Kidney Tubules; Male; Rats; Rats, Inbred F344; Receptor, Angiotensin, Type 1; Renal Circulation; Renin; Tetrazoles

2005
In vivo characterization of the angiotensin-(1-7)-induced dopamine and gamma-aminobutyric acid release in the striatum of the rat.
    The European journal of neuroscience, 2005, Volume: 22, Issue:3

    Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Chromatography; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; gamma-Aminobutyric Acid; Imidazoles; Male; Microdialysis; NG-Nitroarginine Methyl Ester; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Sulfonic Acids; Tetrazoles; Time Factors

2005
Angiotensin II in dorsomedial hypothalamus modulates cardiovascular arousal caused by stress but not feeding in rabbits.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2006, Volume: 290, Issue:1

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Cardiovascular Physiological Phenomena; Dorsomedial Hypothalamic Nucleus; Eating; Excitatory Amino Acid Agonists; GABA Agonists; Kainic Acid; Muscimol; Rabbits; Stress, Psychological; Tetrazoles

2006
Peripheral sympatholytic actions of four AT1 antagonists: are they relevant for long-term antihypertensive efficacy?
    Journal of hypertension, 2005, Volume: 23, Issue:10

    Topics: Acrylates; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Electric Stimulation; Imidazoles; Irbesartan; Losartan; Male; Norepinephrine; Rats; Rats, Inbred SHR; Sympathetic Fibers, Postganglionic; Sympatholytics; Tetrazoles; Thiophenes; Time Factors; Treatment Outcome

2005
Acute effects of candesartan on rat renal haemodynamics and proximal tubular reabsorption.
    Clinical and experimental pharmacology & physiology, 2005, Volume: 32, Issue:9

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Diuresis; Glomerular Filtration Rate; Kidney; Kidney Tubules, Proximal; Lithium; Male; Natriuresis; Potassium; Rats; Rats, Wistar; Renal Plasma Flow; Tetrazoles

2005
A centrally acting, anxiolytic angiotensin II AT1 receptor antagonist prevents the isolation stress-induced decrease in cortical CRF1 receptor and benzodiazepine binding.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2006, Volume: 31, Issue:6

    Topics: Amphibian Proteins; Analysis of Variance; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Autoradiography; Behavior, Animal; Benzimidazoles; Benzodiazepines; Biphenyl Compounds; Cerebral Cortex; Disease Models, Animal; Flunitrazepam; GABA Modulators; In Situ Hybridization; Male; Maze Learning; Peptide Hormones; Peptides; Protein Binding; Pyrimidines; Pyrroles; Rats; Receptor, Angiotensin, Type 2; Receptors, Corticotropin-Releasing Hormone; RNA, Messenger; Social Isolation; Stress, Physiological; Tetrazoles; Tyrosine 3-Monooxygenase

2006
Increased aortic NADPH oxidase activity in rats with genetically high angiotensin-converting enzyme levels.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 46, Issue:6

    Topics: Acetylcholine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Benzimidazoles; Biphenyl Compounds; In Vitro Techniques; Male; NADPH Oxidases; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Rats; Rats, Inbred BN; Rats, Inbred Lew; Superoxides; Tetrazoles; Vasodilation; Vasodilator Agents

2005
Activation of AP-1 through reactive oxygen species by angiotensin II in rat cardiomyocytes.
    Free radical biology & medicine, 2005, Dec-15, Volume: 39, Issue:12

    Topics: Acetylcysteine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Dose-Response Relationship, Drug; Heart Ventricles; HL-60 Cells; Humans; Myocytes, Cardiac; NADPH Oxidases; Onium Compounds; Oxidation-Reduction; Rats; Rats, Wistar; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Tetrazoles; Time Factors; Transcription Factor AP-1

2005
Angiotensin II blockade improves mitochondrial function in spontaneously hypertensive rats.
    Cellular and molecular biology (Noisy-le-Grand, France), 2005, Nov-08, Volume: 51, Issue:6

    Topics: Actins; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Creatinine; Electron Transport Complex IV; Hydrogen Peroxide; Hypertension; Immunohistochemistry; Kidney Cortex; Male; Membrane Potentials; Mitochondria; Nitric Oxide Synthase; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles

2005
Biphasic effects of angiotensin II and receptor antagonism on aggregability and protein kinase C phosphorylation in human platelets.
    Thrombosis and haemostasis, 2005, Volume: 94, Issue:5

    Topics: Adult; Aged; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Blood Platelets; Female; Humans; Imidazoles; In Vitro Techniques; Isoenzymes; Male; Middle Aged; Phosphorylation; Platelet Aggregation; Protein Kinase C; Pyridines; Receptor, Angiotensin, Type 1; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents

2005
High glucose increases extracellular matrix production in pancreatic stellate cells by activating the renin-angiotensin system.
    Journal of cellular biochemistry, 2006, May-15, Volume: 98, Issue:2

    Topics: Angiotensin I; Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Collagen; Connective Tissue Growth Factor; Dose-Response Relationship, Drug; Extracellular Matrix; Extracellular Matrix Proteins; Fibronectins; Fibrosis; Glucose; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Male; Pancreas; Pancreatitis; Ramipril; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Tetrazoles; Transforming Growth Factor beta

2006
Angiotensin II-induced vasodilatation in cerebral arteries is mediated by endothelium-derived hyperpolarising factor.
    European journal of pharmacology, 2006, Feb-15, Volume: 531, Issue:1-3

    Topics: Adenosine Triphosphate; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apamin; Benzimidazoles; Biological Factors; Biphenyl Compounds; Cerebral Arteries; Charybdotoxin; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Imidazoles; In Vitro Techniques; Indomethacin; Male; Neurotoxins; Nitric Oxide Synthase; Nitroarginine; Pyridines; Rats; Rats, Sprague-Dawley; Serotonin; Tetrazoles; Vasoconstriction; Vasoconstrictor Agents

2006
Angiotensin II inhibition reduces stress sensitivity of hypothalamo-pituitary-adrenal axis in spontaneously hypertensive rats.
    Endocrinology, 2006, Volume: 147, Issue:7

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Corticosterone; Gene Expression Regulation; Hypothalamus; Male; Mibefradil; Pituitary-Adrenal System; Ramipril; Rats; Rats, Inbred SHR; Tetrazoles

2006
AT1 receptor blockade regulates the local angiotensin II system in cerebral microvessels from spontaneously hypertensive rats.
    Stroke, 2006, Volume: 37, Issue:5

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Brain; Gene Expression Regulation; Hypertension; Male; Microcirculation; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Signal Transduction; Tetrazoles

2006
Role of chymase-dependent angiotensin II formation in monocrotaline-induced pulmonary hypertensive rats.
    Pediatric research, 2006, Volume: 60, Issue:1

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cell Proliferation; Chymases; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Peptidyl-Dipeptidase A; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; RNA, Messenger; Serine Endopeptidases; Tetrazoles; Tunica Media

2006
Angiotensin II mediates downregulation of aquaporin water channels and key renal sodium transporters in response to urinary tract obstruction.
    American journal of physiology. Renal physiology, 2006, Volume: 291, Issue:5

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aquaporin 1; Aquaporin 2; Aquaporin 3; Aquaporins; Benzimidazoles; Biphenyl Compounds; Cyclooxygenase 2; Down-Regulation; Glomerular Filtration Rate; Male; Phosphates; Polyuria; Rats; Rats, Wistar; Sodium; Sodium-Phosphate Cotransporter Proteins, Type II; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 1; Tetrazoles; Ureteral Obstruction; Vasoconstrictor Agents

2006
Involvement of the somatostatin-2 receptor in the anti-convulsant effect of angiotensin IV against pilocarpine-induced limbic seizures in rats.
    Journal of neurochemistry, 2006, Volume: 98, Issue:4

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Anticonvulsants; Benzimidazoles; Biphenyl Compounds; Dopamine; Glutamic Acid; Hippocampus; Injections, Intraventricular; Limbic System; Male; Microdialysis; Oligopeptides; Pilocarpine; Rats; Rats, Wistar; Receptors, Somatostatin; Seizures; Serotonin; Somatostatin; Tetrazoles

2006
Long-term regulation of proximal tubule acid-base transporter abundance by angiotensin II.
    Kidney international, 2006, Volume: 70, Issue:4

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Gene Expression Regulation; Gene Expression Regulation, Enzymologic; Kidney Tubules, Proximal; Male; Rats; Rats, Inbred SHR; RNA, Messenger; Sodium-Bicarbonate Symporters; Sodium-Hydrogen Exchangers; Sodium-Phosphate Cotransporter Proteins, Type II; Sodium-Potassium-Exchanging ATPase; Tetrazoles

2006
Anti-inflammatory effect of spironolactone on human peripheral blood mononuclear cells.
    Journal of pharmacological sciences, 2006, Volume: 101, Issue:3

    Topics: Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents; Benzimidazoles; Biphenyl Compounds; Captopril; Cells, Cultured; Chemokine CCL2; Dose-Response Relationship, Drug; Female; Humans; Leukocytes, Mononuclear; Male; Mineralocorticoid Receptor Antagonists; Spironolactone; Tetrazoles; Tumor Necrosis Factor-alpha

2006
Atorvastatin inhibits angiotensin II-induced T-type Ca2+ channel expression in endothelial cells.
    Biochemical and biophysical research communications, 2006, Aug-25, Volume: 347, Issue:2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Atorvastatin; Benzimidazoles; Biphenyl Compounds; Calcium Channels, T-Type; Cells, Cultured; Endothelial Cells; Flavonoids; Gene Expression; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Microscopy, Fluorescence; Pyrroles; ras Proteins; Receptor, Angiotensin, Type 1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tetrazoles; Vasoconstrictor Agents

2006
Tumor necrosis factor-alpha and vascular angiotensin II in estrogen-deficient rats.
    Hypertension (Dallas, Tex. : 1979), 2006, Volume: 48, Issue:3

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Endothelium, Vascular; Estrogens; Etanercept; Female; Immunoglobulin G; Mesenteric Arteries; Peptidyl-Dipeptidase A; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Tumor Necrosis Factor; Tetrazoles; Tumor Necrosis Factor-alpha; Vasoconstriction; Vasoconstrictor Agents

2006
Angiotensin II, interstitial inflammation, and the pathogenesis of salt-sensitive hypertension.
    American journal of physiology. Renal physiology, 2006, Volume: 291, Issue:6

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blood Volume; Hypertension, Renal; Lymphocytes; Macrophages; Male; Microcirculation; Nephritis; Rats; Rats, Sprague-Dawley; Renal Circulation; Sodium Chloride, Dietary; Tetrazoles; Vasculitis; Vasoconstrictor Agents

2006
Systemic effects of angiotensin III in conscious dogs during acute double blockade of the renin-angiotensin-aldosterone-system.
    Acta physiologica (Oxford, England), 2006, Volume: 188, Issue:2

    Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin III; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Natriuretic Factor; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Enalaprilat; Female; Glomerular Filtration Rate; Metabolic Clearance Rate; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Tetrazoles

2006
Endothelin-1 and angiotensin II contribute to BNP but not c-fos gene expression response to elevated load in isolated mice hearts.
    Biochimica et biophysica acta, 2007, Volume: 1772, Issue:3

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Coronary Circulation; Endothelin Receptor Antagonists; Endothelin-1; Gene Expression; Gene Expression Regulation; Genes, fos; Heart; Heart Ventricles; In Vitro Techniques; Male; Mice; Natriuretic Peptide, Brain; Receptor, Angiotensin, Type 1; Tetrazoles; Up-Regulation

2007
Attenuation of angiotensin II signaling recouples eNOS and inhibits nonendothelial NOX activity in diabetic mice.
    Diabetes, 2007, Volume: 56, Issue:1

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Captopril; Diabetes Mellitus, Experimental; Hydrogen Peroxide; Hyperglycemia; Mice; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type III; Signal Transduction; Superoxides; Tetrazoles; Vasodilation

2007
Angiotensin II-induced genomic damage in renal cells can be prevented by angiotensin II type 1 receptor blockage or radical scavenging.
    American journal of physiology. Renal physiology, 2007, Volume: 292, Issue:5

    Topics: Acetylcysteine; alpha-Tocopherol; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Cell Line; Cell Nucleus; Comet Assay; DNA Damage; Dose-Response Relationship, Drug; Flow Cytometry; Free Radical Scavengers; Humans; Imidazoles; Kidney; Pyridines; Rats; Reactive Oxygen Species; Swine; Tetrazoles

2007
Pressure overload-induced transient oxidative stress mediates perivascular inflammation and cardiac fibrosis through angiotensin II.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2006, Volume: 29, Issue:9

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Fibrosis; Heart Ventricles; Hypertension; Inflammation; Male; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Tetrazoles; Time Factors; Ventricular Remodeling

2006
[Renin-angiotensin system in mesenteric adipose tissues in rats with metabolic syndrome].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2006, Volume: 28, Issue:6

    Topics: Adipocytes; Adipose Tissue; Angiotensin II; Angiotensinogen; Animals; Benzimidazoles; Biphenyl Compounds; Calcium; Captopril; Cells, Cultured; Male; Metabolic Syndrome; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazoles

2006
Long-term, high-dosage candesartan suppresses inflammation and injury in chronic kidney disease: nonhemodynamic renal protection.
    Journal of the American Society of Nephrology : JASN, 2007, Volume: 18, Issue:3

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Chemokine CCL2; Chemokine CCL5; Dose-Response Relationship, Drug; Inflammation; Kidney; Kidney Failure, Chronic; Kidney Glomerulus; Male; NF-kappa B; Proteinuria; Rats; Rats, Inbred SHR; Tetrazoles; Vasoconstrictor Agents

2007
Albumin overload induces adaptive responses in human proximal tubular cells through oxidative stress but not via angiotensin II type 1 receptor.
    American journal of physiology. Renal physiology, 2007, Volume: 292, Issue:6

    Topics: Adaptation, Physiological; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antioxidants; Benzimidazoles; Biphenyl Compounds; Blotting, Western; Cell Line; Cell Nucleus; Cell Shape; Cell Survival; DNA, Complementary; Endocytosis; Kidney Tubules, Proximal; Lipid Metabolism; Lipid Peroxidation; Oxidative Stress; Receptor, Angiotensin, Type 1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serum Albumin; Sulfhydryl Compounds; Tetrazoles; Transcription Factors

2007
AT1 receptor blockade prevents interstitial and glomerular apoptosis but not fibrosis in pigs with neonatal induced partial unilateral ureteral obstruction.
    American journal of physiology. Renal physiology, 2007, Volume: 292, Issue:6

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Apoptosis; Benzimidazoles; Biphenyl Compounds; Capillaries; Caspase 3; Cell Count; Collagen; Female; Fibrosis; Hydroxyproline; Immunohistochemistry; Kidney Glomerulus; Kidney Tubules; Nephritis, Interstitial; Swine; Tetrazoles; Tissue Fixation; Ureteral Obstruction

2007
High-glucose-induced regulation of intracellular ANG II synthesis and nuclear redistribution in cardiac myocytes.
    American journal of physiology. Heart and circulatory physiology, 2007, Volume: 293, Issue:2

    Topics: Actin Cytoskeleton; Active Transport, Cell Nucleus; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Animals, Newborn; Benzimidazoles; Biphenyl Compounds; Cell Nucleus; Cells, Cultured; Chymases; Cytoplasm; Dose-Response Relationship, Drug; Extracellular Space; Glucose; Heart Ventricles; Isoproterenol; Myocytes, Cardiac; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Sympathomimetics; Tetrazoles; Time Factors

2007
Intracellular renin-angiotensin system: the tip of the intracrine physiology iceberg.
    American journal of physiology. Heart and circulatory physiology, 2007, Volume: 293, Issue:2

    Topics: Actin Cytoskeleton; Active Transport, Cell Nucleus; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Benzimidazoles; Biphenyl Compounds; Cell Nucleus; Chymases; Cytoplasm; Extracellular Space; Glucose; Isoproterenol; Myocytes, Cardiac; Peptidyl-Dipeptidase A; Rats; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Signal Transduction; Sympathomimetics; Tetrazoles

2007
Angiotensin II and endothelin-1 augment the vascular complications of diabetes via JAK2 activation.
    American journal of physiology. Heart and circulatory physiology, 2007, Volume: 293, Issue:2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Thoracic; Atrasentan; Benzimidazoles; Biphenyl Compounds; Blood Glucose; Blood Pressure; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Endothelin A Receptor Antagonists; Endothelin-1; Enzyme Activation; Intracellular Signaling Peptides and Proteins; Janus Kinase 2; Male; Phosphorylation; Protein Kinase Inhibitors; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Pyrrolidines; Rats; Receptor, Angiotensin, Type 1; Receptor, Endothelin A; Signal Transduction; STAT1 Transcription Factor; STAT3 Transcription Factor; Tetrazoles; Time Factors; Tyrphostins; Vasodilation

2007
Cross-inhibition of angiotensin AT1 receptors supports the concept of receptor oligomerization.
    Neurochemistry international, 2007, Volume: 51, Issue:5

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Chlorocebus aethiops; COS Cells; DNA, Complementary; Inositol Phosphates; Muscle, Smooth, Vascular; Mutagenesis, Site-Directed; Mutation; Rats; Receptor, Angiotensin, Type 1; Tetrazoles; Transfection

2007
Angiotensin AT1 receptor blockers suppress ischemia/reperfusion-induced gastric injury in rats.
    Inflammopharmacology, 2007, Volume: 15, Issue:4

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Capillary Permeability; Gastric Mucosa; Hydrogen Peroxide; Losartan; Male; Microcirculation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tetrazoles; Valine; Valsartan

2007
Angiotensin II type 2 receptor vasoactivity in internal mammary arteries of patients with coronary artery disease.
    Journal of cardiovascular pharmacology, 2007, Volume: 50, Issue:4

    Topics: Acetylcholine; Adrenergic alpha-Antagonists; Adult; Aged; Aged, 80 and over; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Coronary Artery Disease; Female; Gene Expression; Humans; Imidazoles; In Vitro Techniques; Male; Mammary Arteries; Middle Aged; Oligopeptides; Phentolamine; Phenylephrine; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sodium Nitrite; Tetrazoles; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2007
Upregulation of cortical COX-2 in salt-sensitive hypertension: role of angiotensin II and reactive oxygen species.
    American journal of physiology. Renal physiology, 2008, Volume: 294, Issue:2

    Topics: Amlodipine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Antioxidants; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cyclic N-Oxides; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Gene Expression; Hypertension; Kidney Cortex; Kidney Medulla; Male; Membrane Proteins; Rats; Rats, Inbred Dahl; Reactive Oxygen Species; Sodium Chloride, Dietary; Spin Labels; Tetrazoles; Up-Regulation

2008
Conversion of renal angiotensin II to angiotensin III is critical for AT2 receptor-mediated natriuresis in rats.
    Hypertension (Dallas, Tex. : 1979), 2008, Volume: 51, Issue:2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin III; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; CD13 Antigens; Drug Synergism; Female; Glutamyl Aminopeptidase; Imidazoles; Kidney; Methionine; Natriuresis; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Sodium, Dietary; Sulfonic Acids; Tetrazoles

2008
Angiotensin II type 2 receptors and nitric oxide sustain oxygenation in the clipped kidney of early Goldblatt hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 2008, Volume: 51, Issue:2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Enalaprilat; Enzyme Inhibitors; Glomerular Filtration Rate; Hypertension, Renovascular; Imidazoles; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxygen; Partial Pressure; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renal Circulation; Surgical Instruments; Tetrazoles; Vascular Resistance

2008
Activation of the intracellular renin-angiotensin system in cardiac fibroblasts by high glucose: role in extracellular matrix production.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:4

    Topics: Adrenergic beta-Agonists; Amides; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Benzazepines; Benzimidazoles; Biphenyl Compounds; Blotting, Western; Cells, Cultured; Collagen Type I; Dose-Response Relationship, Drug; Extracellular Matrix; Fibroblasts; Fumarates; Glucose; Heart Ventricles; Isoproterenol; Microscopy, Confocal; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; Tetrazoles; Time Factors; Transforming Growth Factor beta; Up-Regulation

2008
Chronic candesartan alters expression and activity of NKCC2, NCC, and ENaC in the obese Zucker rat.
    American journal of physiology. Renal physiology, 2008, Volume: 294, Issue:5

    Topics: Amiloride; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blotting, Western; Diuretics; Epithelial Sodium Channels; Furosemide; Hypertrophy; Kidney Tubules, Proximal; Male; Obesity; Rats; Rats, Zucker; Receptor, Angiotensin, Type 1; Receptors, Drug; Renin; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sodium-Phosphate Cotransporter Proteins, Type IIb; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 1; Solute Carrier Family 12, Member 3; Symporters; Tetrazoles

2008
Angiotensin II increases the expression of the transcription factor ETS-1 in mesangial cells.
    American journal of physiology. Renal physiology, 2008, Volume: 294, Issue:5

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blotting, Western; Cells, Cultured; Cyclooxygenase 2; Fibronectins; Glomerular Mesangium; Male; Mitogen-Activated Protein Kinases; Protein Kinase C; Proto-Oncogene Protein c-ets-1; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Stimulation, Chemical; Tetrazoles

2008
Modulation of reflex function by endogenous angiotensins in older transgenic rats with low glial angiotensinogen.
    Hypertension (Dallas, Tex. : 1979), 2008, Volume: 51, Issue:5

    Topics: Aging; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Angiotensins; Animals; Animals, Genetically Modified; Baroreflex; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Heart Rate; Male; Neuroglia; Peptide Fragments; Rats; Renin-Angiotensin System; Solitary Nucleus; Tetrazoles

2008
Regulation of endothelial proliferation by the renin-angiotensin system in human umbilical vein endothelial cells.
    Reproduction (Cambridge, England), 2008, Volume: 136, Issue:1

    Topics: Angiopoietin-1; Angiopoietin-2; Angiotensin II; Benzimidazoles; Biphenyl Compounds; Cell Proliferation; Cells, Cultured; Endothelial Cells; Female; Humans; Immunohistochemistry; Neovascularization, Physiologic; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; Tetrazoles; Umbilical Veins; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1

2008
Potential role of Renin-Angiotensin-system for tumor angiogenesis in receptor negative breast cancer.
    Gynecologic oncology, 2008, Volume: 109, Issue:3

    Topics: Angiopoietin-1; Angiopoietin-2; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Basic Helix-Loop-Helix Transcription Factors; Benzimidazoles; Biphenyl Compounds; Breast Neoplasms; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Neovascularization, Pathologic; Receptor, Angiotensin, Type 1; Receptors, Estrogen; Renin-Angiotensin System; Tetrazoles; Tissue Inhibitor of Metalloproteinase-1; Vascular Endothelial Growth Factor A

2008
Selective type 1 angiotensin II receptor blockade attenuates oxidative stress and regulates angiotensin II receptors in the canine failing heart.
    Molecular and cellular biochemistry, 2008, Volume: 317, Issue:1-2

    Topics: Aldehydes; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Dogs; Echocardiography; Heart Failure; Hemodynamics; Male; Oxidative Stress; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles; Ventricular Dysfunction, Left; Ventricular Remodeling

2008
Pulsatile mechanical pressure promotes Angiotensin-converting enzyme expression in aortic smooth muscle cells.
    Cardiovascular drugs and therapy, 2008, Volume: 22, Issue:5

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Aorta; Atmospheric Pressure; Benzimidazoles; Biphenyl Compounds; Captopril; Cell Line; Cell Proliferation; Colorimetry; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gene Expression Regulation, Enzymologic; Humans; Immunoblotting; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Muscle, Smooth, Vascular; Peptidyl-Dipeptidase A; Phosphorylation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stress, Mechanical; Tetrazoles; Time Factors

2008
The effect of recombinant aminopeptidase A on hypertension in spontaneously hypertensive rats: its effect in comparison with candesartan.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2008, Volume: 40, Issue:12

    Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Baculoviridae; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Genetic Vectors; Glutamyl Aminopeptidase; Humans; Hypertension; Male; Mutation; Nitroprusside; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Recombinant Proteins; Tetrazoles

2008
Intracellular angiotensin II production in diabetic rats is correlated with cardiomyocyte apoptosis, oxidative stress, and cardiac fibrosis.
    Diabetes, 2008, Volume: 57, Issue:12

    Topics: Amides; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Apoptosis; Benzazepines; Benzimidazoles; Biphenyl Compounds; Diabetes Mellitus, Experimental; Endomyocardial Fibrosis; Fumarates; Insulin; Myocytes, Cardiac; Oxidative Stress; Rats; Renin; Tetrazoles

2008
Involvement of angiotensin II-dependent vascular endothelial growth factor gene expression via NADPH oxidase in the retina in a type 2 diabetic rat model.
    Current eye research, 2008, Volume: 33, Issue:10

    Topics: Administration, Oral; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Thoracic; Benzimidazoles; Biphenyl Compounds; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Gene Expression Regulation; NADPH Oxidases; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Retina; RNA, Messenger; Tetrazoles; Vascular Endothelial Growth Factor A

2008
Loss of biphasic effect on Na/K-ATPase activity by angiotensin II involves defective angiotensin type 1 receptor-nitric oxide signaling.
    Hypertension (Dallas, Tex. : 1979), 2008, Volume: 52, Issue:6

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Antioxidants; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Buthionine Sulfoximine; Cyclic GMP; Cyclic N-Oxides; Enzyme Inhibitors; Focal Adhesion Kinase 2; Hypertension, Renal; Kidney Tubules, Proximal; Male; Mitogen-Activated Protein Kinases; Nitric Oxide; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Signal Transduction; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase; Spin Labels; Tetrazoles; Vasoconstrictor Agents

2008
Angiotensin II regulates V2 receptor and pAQP2 during ureteral obstruction.
    American journal of physiology. Renal physiology, 2009, Volume: 296, Issue:1

    Topics: Adenylyl Cyclases; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aquaporin 2; Benzimidazoles; Biphenyl Compounds; Colforsin; Cyclic AMP; Disease Models, Animal; GTP-Binding Protein alpha Subunits, Gs; Kidney Medulla; Male; Rats; Rats, Wistar; Receptors, Vasopressin; RNA, Messenger; Sodium Fluoride; Tetrazoles; Ureteral Obstruction

2009
Angiotensin II upregulates acyl-CoA:cholesterol acyltransferase-1 via the angiotensin II Type 1 receptor in human monocyte-macrophages.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2008, Volume: 31, Issue:9

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Atherosclerosis; Benzimidazoles; Biphenyl Compounds; Cell Differentiation; Cells, Cultured; Dose-Response Relationship, Drug; Endocytosis; Foam Cells; Humans; Imidazoles; Macrophages; Male; Oligopeptides; Radioimmunoassay; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Signal Transduction; Sterol O-Acyltransferase; Tetrazoles; Up-Regulation; Vasoconstrictor Agents; Vasodilator Agents

2008
Candesartan ameliorates cardiac dysfunction observed in angiotensin-converting enzyme 2-deficient mice.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2008, Volume: 31, Issue:10

    Topics: Age Factors; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Benzimidazoles; Biphenyl Compounds; Cardiomegaly; Disease Models, Animal; Echocardiography; Female; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Myocardium; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Tetrazoles

2008
Peripherally administered angiotensin II AT1 receptor antagonists are anti-stress compounds in vivo.
    Annals of the New York Academy of Sciences, 2008, Volume: 1148

    Topics: Adrenocorticotropic Hormone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Brain; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Corticotropin-Releasing Hormone; Receptors, GABA-A; Social Isolation; Stomach Ulcer; Stress, Psychological; Tetrazoles

2008
Plasma kallikrein mediates angiotensin II type 1 receptor-stimulated retinal vascular permeability.
    Hypertension (Dallas, Tex. : 1979), 2009, Volume: 53, Issue:2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blood-Retinal Barrier; Capillary Permeability; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Disease Models, Animal; Hypertension; Kallikreins; Kinins; Male; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Retinal Artery; Streptozocin; Tetrazoles

2009
Role of angiotensin II and oxidative stress in vascular insulin resistance linked to hypertension.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 296, Issue:3

    Topics: Acetylcholine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Body Weight; C-Reactive Protein; Cyclic N-Oxides; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Hypertension; Insulin; Insulin Resistance; JNK Mitogen-Activated Protein Kinases; Male; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred Dahl; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Signal Transduction; Sodium Chloride, Dietary; Spin Labels; Superoxide Dismutase; Tetrazoles; Vasodilation; Vasodilator Agents

2009
Candesartan attenuates Angiotensin II-induced mesangial cell apoptosis via TLR4/MyD88 pathway.
    Biochemical and biophysical research communications, 2009, Feb-27, Volume: 380, Issue:1

    Topics: Angiotensin II; Animals; Antioxidants; Apoptosis; Benzimidazoles; Biphenyl Compounds; Cell Line; Mesangial Cells; Myeloid Differentiation Factor 88; Oxidative Stress; Rats; Reactive Oxygen Species; Tetrazoles; Toll-Like Receptor 4

2009
Angiotensin II type 1 receptor mediates partially hyposmotic-induced increase of I (Ks) current in guinea pig atrium.
    Pflugers Archiv : European journal of physiology, 2009, Volume: 458, Issue:5

    Topics: Action Potentials; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Cell Shape; Electrophysiological Phenomena; Enzyme Inhibitors; Guinea Pigs; Heart Atria; Hypotonic Solutions; Immunoglobulin G; Membrane Potentials; Myocytes, Cardiac; Osmolar Concentration; Potassium; Protein-Tyrosine Kinases; Receptor, Angiotensin, Type 1; Signal Transduction; Tetrazoles

2009
The effect of angiotensin II on the number of macula densa cells through the AT1 receptor.
    Nephron. Physiology, 2009, Volume: 112, Issue:2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Cell Count; Cell Proliferation; Cell Transdifferentiation; Epithelial Cells; Juxtaglomerular Apparatus; Male; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Tetrazoles

2009
Local angiotensin II-generation in human gastric cancer: correlation with tumor progression through the activation of ERK1/2, NF-kappaB and survivin.
    International journal of oncology, 2009, Volume: 34, Issue:6

    Topics: Adenocarcinoma; Adenocarcinoma, Clear Cell; Adenocarcinoma, Mucinous; Adult; Aged; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Benzimidazoles; Biphenyl Compounds; Blotting, Western; Carcinoma, Medullary; Case-Control Studies; Cell Proliferation; Disease Progression; Electrophoretic Mobility Shift Assay; Female; Gastric Mucosa; Humans; Immunoenzyme Techniques; Inhibitor of Apoptosis Proteins; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Microtubule-Associated Proteins; Middle Aged; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; Peritoneal Neoplasms; Receptor, Angiotensin, Type 1; Stomach; Stomach Neoplasms; Survival Rate; Survivin; Tetrazoles; Tumor Cells, Cultured

2009
Effects of phorbol ester-sensitive PKC (c/nPKC) activation on the production of adiponectin in 3T3-L1 adipocytes.
    IUBMB life, 2009, Volume: 61, Issue:6

    Topics: 3T3-L1 Cells; Adipocytes; Adiponectin; Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Carbazoles; Chromones; Enzyme Activation; Gene Expression; Glucose; Insulin; Mice; Morpholines; NF-kappa B; PPAR gamma; Protein Kinase C; Tetradecanoylphorbol Acetate; Tetrazoles; Tumor Necrosis Factor-alpha

2009
Conditional expression of type 2 angiotensin II receptor in rat vascular smooth muscle cells reveals the interplay of the angiotensin system in matrix metalloproteinase 2 expression and vascular remodeling.
    International journal of molecular medicine, 2009, Volume: 24, Issue:1

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Endothelium, Vascular; Imidazoles; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Muscle, Smooth, Vascular; Pyridines; Rats; Receptor, Angiotensin, Type 2; Signal Transduction; Tetrazoles

2009
Electrophysiological responses of sympathetic preganglionic neurons to ANG II and aldosterone.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 297, Issue:3

    Topics: Aldosterone; Anesthetics, Local; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Autonomic Fibers, Preganglionic; Benzimidazoles; Biphenyl Compounds; Eplerenone; Excitatory Postsynaptic Potentials; Female; In Vitro Techniques; Male; Mineralocorticoid Receptor Antagonists; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Rats, Wistar; Spironolactone; Synaptic Transmission; Tetrazoles; Tetrodotoxin; Time Factors

2009
Involvement of vascular angiotensin II-forming enzymes in the progression of aortic abdominal aneurysms in angiotensin II- infused ApoE-deficient mice.
    Journal of atherosclerosis and thrombosis, 2009, Volume: 16, Issue:3

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Aortic Aneurysm, Abdominal; Apolipoproteins E; Benzimidazoles; Biphenyl Compounds; Chymases; Disease Progression; Lisinopril; Mice; Mice, Knockout; Peptidyl-Dipeptidase A; Tetrazoles

2009
Effects of angiotensin on the expression of fibrosis-associated cytokines, growth factors, and matrix proteins in human lung fibroblasts.
    Journal of clinical pharmacy and therapeutics, 2009, Volume: 34, Issue:3

    Topics: Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Cell Proliferation; Cells, Cultured; Collagen; Cytokines; Elastin; Extracellular Matrix Proteins; Fibroblasts; Gene Expression Regulation; Humans; Intercellular Signaling Peptides and Proteins; Lung; Microscopy, Confocal; RNA, Messenger; Tetrazoles

2009
Exaggerated blood pressure variability superimposed on hypertension aggravates cardiac remodeling in rats via angiotensin II system-mediated chronic inflammation.
    Hypertension (Dallas, Tex. : 1979), 2009, Volume: 54, Issue:4

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Chemokine CCL2; Chronic Disease; Disease Models, Animal; Heart Diseases; Heart Ventricles; Hypertension; Hypertrophy; Inflammation; Macrophages; Male; Myocytes, Cardiac; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles; Transforming Growth Factor beta; Ventricular Remodeling

2009
Changes of renal AQP2, ENaC, and NHE3 in experimentally induced heart failure: response to angiotensin II AT1 receptor blockade.
    American journal of physiology. Renal physiology, 2009, Volume: 297, Issue:6

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aquaporin 2; Benzimidazoles; Biphenyl Compounds; Body Water; Epithelial Sodium Channels; Heart Failure; Kidney; Kidney Cortex; Kidney Medulla; Phosphorylation; Potassium; Rats; Rats, Wistar; Sodium; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 1; Tetrazoles; Tissue Distribution

2009
Angiotensin II receptors are expressed and functional in human esophageal mucosa.
    American journal of physiology. Gastrointestinal and liver physiology, 2009, Volume: 297, Issue:5

    Topics: Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Benzimidazoles; Biopsy; Biphenyl Compounds; Blood Vessels; Electric Impedance; Electrophysiological Phenomena; Epithelial Cells; Esophagus; Female; Gene Expression; Humans; Hydrochloric Acid; Imidazoles; Losartan; Male; Middle Aged; Mucous Membrane; Peptidyl-Dipeptidase A; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles

2009
Long-term blockade of L/N-type Ca(2+) channels by cilnidipine ameliorates repolarization abnormality of the canine hypertrophied heart.
    British journal of pharmacology, 2009, Volume: 158, Issue:5

    Topics: Action Potentials; Amlodipine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Atrioventricular Block; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Cardiomegaly; Chronic Disease; Dihydropyridines; Dogs; Electrocardiography; Epinephrine; Female; Male; Neurotransmitter Agents; Norepinephrine; Tetrazoles; Time Factors

2009
Renal vasoconstrictor and pressor responses to angiotensin IV in mice are AT1a-receptor mediated.
    Journal of hypertension, 2010, Volume: 28, Issue:3

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Base Sequence; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Body Weight; DNA Primers; Endothelin-1; Hemodynamics; Kidney; Mice; Mice, Inbred C57BL; Mice, Knockout; Organ Size; Receptor, Angiotensin, Type 1; Tetrazoles; Vasoconstriction

2010
Systemic candesartan reduces brain angiotensin II via downregulation of brain renin-angiotensin system.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2010, Volume: 33, Issue:2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blood-Brain Barrier; Body Weight; Brain Chemistry; Down-Regulation; Male; Permeability; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Tetrazoles

2010
Role of angiotensin II in the remodeling induced by a chronic increase in flow in rat mesenteric resistance arteries.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:1

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Benzimidazoles; Biphenyl Compounds; Blood Flow Velocity; Blotting, Western; Butadienes; Cyclic N-Oxides; Extracellular Signal-Regulated MAP Kinases; Hydralazine; Male; Mesenteric Arteries; Mice; Mice, Knockout; Microscopy, Confocal; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Nitriles; Perindopril; Rats; Rats, Wistar; Reactive Oxygen Species; Spin Labels; Tetrazoles; Vascular Resistance; Vasodilator Agents

2010
Expressions of inducible nitric oxide synthase and cyclooxygenase-2 in gastric ischemia-reperfusion: role of angiotensin II.
    The Journal of surgical research, 2010, Jun-01, Volume: 161, Issue:1

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Captopril; Cyclooxygenase 2; Dinoprostone; Gastritis; Imidazoles; Male; Neutrophils; Nitric Oxide; Nitric Oxide Synthase Type II; Peroxidase; Pyridines; Rats; Rats, Wistar; Reperfusion Injury; Tetrazoles

2010
Angiotensin II-activated protein kinase D mediates acute aldosterone secretion.
    Molecular and cellular endocrinology, 2010, Apr-12, Volume: 317, Issue:1-2

    Topics: Adenoviridae; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Cattle; Enzyme Activation; Imidazoles; Mutant Proteins; Potassium; Protein Kinase C; Pyridines; Receptor, Angiotensin, Type 1; Tetradecanoylphorbol Acetate; Tetrazoles; Time Factors; Zona Glomerulosa

2010
The mechanism of distinct diurnal variations of renin-angiotensin system in aorta and heart of spontaneously hypertensive rats.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2009, Volume: 31, Issue:8

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Benzimidazoles; Biphenyl Compounds; Circadian Rhythm; Down-Regulation; Genetic Markers; Male; Myocardium; NADPH Oxidases; Plasminogen Activator Inhibitor 1; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System; Serine Proteinase Inhibitors; Tetrazoles; Transforming Growth Factor beta1

2009
Angiotensin II promotes development of the renal microcirculation through AT1 receptors.
    Journal of the American Society of Nephrology : JASN, 2010, Volume: 21, Issue:3

    Topics: Adrenalectomy; Angiopoietin-1; Angiopoietin-2; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Benzimidazoles; Biphenyl Compounds; Capillaries; Female; Kidney; Mice; Mice, Knockout; Neovascularization, Physiologic; Polyuria; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, TIE-2; Renal Circulation; RNA, Messenger; Tetrazoles; Vascular Endothelial Growth Factor A

2010
Developmental effect of antenatal exposure to betamethasone on renal angiotensin II activity in the young adult sheep.
    American journal of physiology. Renal physiology, 2010, Volume: 298, Issue:4

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Benzimidazoles; Betamethasone; Biphenyl Compounds; Blood Pressure; Female; Glomerular Filtration Rate; Glucocorticoids; Imidazoles; Infusions, Intra-Arterial; Kidney; Lithium; Male; Organ Size; Pregnancy; Prenatal Exposure Delayed Effects; Pyridines; Random Allocation; Renal Blood Flow, Effective; Sheep; Sodium; Tetrazoles; Vascular Resistance

2010
Aliskiren inhibits intracellular angiotensin II levels without affecting (pro)renin receptor signals in human podocytes.
    American journal of hypertension, 2010, Volume: 23, Issue:5

    Topics: Amides; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Fumarates; Humans; Imidazolidines; Phosphorylation; Podocytes; Prorenin Receptor; Receptors, Cell Surface; Renin; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Tetrazoles

2010
Mechanisms for perivascular adipose tissue-mediated potentiation of vascular contraction to perivascular neuronal stimulation: the role of adipocyte-derived angiotensin II.
    European journal of pharmacology, 2010, May-25, Volume: 634, Issue:1-3

    Topics: Adipocytes; Adipose Tissue; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Electric Stimulation; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Neurons; Oligodendroglia; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Tetrazoles; Vasoconstriction

2010
Regression of glomerulosclerosis in response to transient treatment with angiotensin II blockers is attenuated by blockade of matrix metalloproteinase-2.
    Kidney international, 2010, Volume: 78, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensins; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Hypertension; Kidney; Kidney Diseases; Kidney Glomerulus; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Random Allocation; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Tetrazoles; Time Factors

2010
Stimulation of renin secretion by angiotensin II blockade is Gsalpha-dependent.
    Journal of the American Society of Nephrology : JASN, 2010, Volume: 21, Issue:6

    Topics: Adenylyl Cyclases; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Captopril; Catecholamines; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enalapril; Female; GTP-Binding Protein alpha Subunits, Gs; Juxtaglomerular Apparatus; Male; Mice; Mice, Knockout; Models, Animal; Nitric Oxide; Prostaglandins; Renin; Signal Transduction; Tetrahydroisoquinolines; Tetrazoles

2010
Angiotensin-(1-9) regulates cardiac hypertrophy in vivo and in vitro.
    Journal of hypertension, 2010, Volume: 28, Issue:5

    Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Bradykinin; Cardiomegaly; Cell Enlargement; Cells, Cultured; Enalapril; Humans; Hypertrophy, Left Ventricular; In Vitro Techniques; Insulin-Like Growth Factor I; Male; Myocardial Infarction; Myocytes, Cardiac; Norepinephrine; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Tetrazoles; Ventricular Function, Left

2010
A single-nucleotide polymorphism of alanine to threonine at position 163 of the human angiotensin II type 1 receptor impairs Losartan affinity.
    Pharmacogenetics and genomics, 2010, Volume: 20, Issue:6

    Topics: Alanine; Angiotensin II; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Chlorocebus aethiops; COS Cells; Humans; Imidazoles; Inositol Phosphates; Irbesartan; Losartan; Polymorphism, Single Nucleotide; Receptor, Angiotensin, Type 1; Telmisartan; Tetrazoles; Threonine; Valine; Valsartan

2010
Effects of angiotensin receptor blockade on atrial electrical remodelling and the 'second factor' in a goat burst-paced model of atrial fibrillation.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2010, Volume: 11, Issue:4

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Atrial Fibrillation; Benzimidazoles; Biphenyl Compounds; Disease Models, Animal; Electrophysiological Phenomena; Female; Goats; Heart Atria; Receptors, Angiotensin; Tetrazoles; Time Factors; Ventricular Function

2010
Involvement of angiotensin II in the remodeling induced by a chronic decrease in blood flow in rat mesenteric resistance arteries.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2010, Volume: 33, Issue:8

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Blood Flow Velocity; Chronic Disease; Extracellular Signal-Regulated MAP Kinases; Hypertension; Mesenteric Arteries; Mice; Mice, Knockout; Nitric Oxide Synthase Type III; Perindopril; Rats; Rats, Wistar; Reactive Oxygen Species; Tetrazoles; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents

2010
Estrogen and angiotensin interaction in the substantia nigra. Relevance to postmenopausal Parkinson's disease.
    Experimental neurology, 2010, Volume: 224, Issue:2

    Topics: Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Cell Death; Dopamine; Estradiol; Estrogens; Female; Humans; Neuroglia; Neurons; Ovariectomy; Oxidopamine; Parkinson Disease; Peptidyl-Dipeptidase A; Postmenopause; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Substantia Nigra; Tetrazoles

2010
[Suppression of renin-angiotensin system and cancer therapy (discussion)].
    Nihon rinsho. Japanese journal of clinical medicine, 2010, Volume: 68, Issue:6

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Cimetidine; Cyclooxygenase 2 Inhibitors; Deoxycytidine; Drug Combinations; Drug Therapy, Combination; Gemcitabine; Humans; Hypertension; Interferon-alpha; Life Style; Neoplasms; Oxonic Acid; Renin-Angiotensin System; Tegafur; Tetrazoles

2010
Angiotensin II type 1 receptor-mediated augmentation of urinary excretion of endogenous angiotensin II in Val5-angiotensin II-infused rats.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 56, Issue:3

    Topics: Analysis of Variance; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Chromatography, Liquid; Hypertension, Renal; Kidney; Male; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Tetrazoles

2010
Angiotensin II sustains brain inflammation in mice via TGF-beta.
    The Journal of clinical investigation, 2010, Volume: 120, Issue:8

    Topics: Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Chronic Disease; Encephalomyelitis, Autoimmune, Experimental; Female; Mice; Mice, Inbred C57BL; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Signal Transduction; Tetrazoles; Thrombospondin 1; Transforming Growth Factor beta

2010
Angiotensin II and NADPH oxidase increase ADMA in vascular smooth muscle cells.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 56, Issue:3

    Topics: Analysis of Variance; Angiotensin II; Animals; Arginine; Benzimidazoles; Biphenyl Compounds; Blotting, Western; Cells, Cultured; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidases; Rats; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Tetrazoles

2010
Enhanced urinary angiotensinogen excretion in Cyp1a1-Ren2 transgenic rats with inducible ANG II-dependent malignant hypertension.
    The American journal of the medical sciences, 2010, Volume: 340, Issue:5

    Topics: Angiotensin II; Angiotensinogen; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Body Weight; Cytochrome P-450 CYP1A1; Humans; Hypertension, Malignant; Male; Middle Aged; Rats; Rats, Transgenic; Renin; Tetrazoles

2010
On the origin of urinary angiotensin II.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 56, Issue:4

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Kidney; Rats; Receptor, Angiotensin, Type 1; Swine; Tetrazoles

2010
Reduction of renal dopamine receptor expression in obese Zucker rats: role of sex and angiotensin II.
    American journal of physiology. Renal physiology, 2010, Volume: 299, Issue:5

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blotting, Western; Body Composition; Diet; Female; Glyceraldehyde-3-Phosphate Dehydrogenases; Insulin Resistance; Kidney; Male; Obesity; Rats; Rats, Zucker; Receptors, Dopamine; Sex Characteristics; Sodium Chloride, Dietary; Tetrazoles

2010
Aging-related changes in the nigral angiotensin system enhances proinflammatory and pro-oxidative markers and 6-OHDA-induced dopaminergic degeneration.
    Neurobiology of aging, 2012, Volume: 33, Issue:1

    Topics: Aging; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Dopaminergic Neurons; Inflammation Mediators; Interleukin-1beta; Male; Molecular Targeted Therapy; NADPH Oxidases; Nerve Degeneration; Oxidative Stress; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Substantia Nigra; Tetrazoles; Tumor Necrosis Factor-alpha

2012
Angiotensin blockade in diabetic patients decreases insulin resistance-associated low-grade inflammation.
    European journal of clinical investigation, 2011, Volume: 41, Issue:6

    Topics: Adult; Aged; Angiotensin II; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Diabetes Mellitus, Type 2; Female; Humans; Inflammation Mediators; Insulin Resistance; Interleukin-6; Male; Middle Aged; Regression Analysis; Tetrazoles; Time Factors; Treatment Outcome; Vasoconstrictor Agents

2011
Angiotensin II induces human astrocyte senescence through reactive oxygen species production.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2011, Volume: 34, Issue:4

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antioxidants; Astrocytes; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Cellular Senescence; Cyclic N-Oxides; Dose-Response Relationship, Drug; Humans; NADPH Oxidases; Reactive Oxygen Species; Spin Labels; Superoxides; Tetrazoles

2011
[Prevention of hypertension by drugs and immunization against angiotensin II].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2011, Feb-10, Volume: 100, Issue:2

    Topics: Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Female; Humans; Hypertension; Male; Middle Aged; Ramipril; Tetrazoles; Vaccines

2011
AT1 receptor antagonist candesartan attenuates genomic damage in peripheral blood lymphocytes of patients on maintenance hemodialysis treatment.
    Kidney & blood pressure research, 2011, Volume: 34, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Antimutagenic Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cell Nucleus; Cell Separation; Female; Glycation End Products, Advanced; Humans; Hypertension; Kidney Failure, Chronic; Kidney Function Tests; Lymphocytes; Male; Micronucleus Tests; Middle Aged; Renal Dialysis; Tetrazoles

2011
Regulation of angiotensinogen by angiotensin II in mouse primary astrocyte cultures.
    Journal of neurochemistry, 2011, Volume: 119, Issue:1

    Topics: Adenoviridae; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Astrocytes; Benzimidazoles; Biphenyl Compounds; Brain; Brain Chemistry; Cells, Cultured; Dexamethasone; Feedback, Physiological; Imidazoles; Immunohistochemistry; Inositol Phosphates; Liver; Mice; Mice, Inbred C57BL; Pyridines; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Tetrazoles

2011
Abilities of candesartan and other AT(1) receptor blockers to impair angiotensin II-induced AT(1) receptor activation after wash-out.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2012, Volume: 13, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Chlorocebus aethiops; COS Cells; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Inositol Phosphates; Mutant Proteins; Receptor, Angiotensin, Type 1; Tetrazoles

2012
Increased renin excretion is associated with augmented urinary angiotensin II levels in chronic angiotensin II-infused hypertensive rats.
    American journal of physiology. Renal physiology, 2011, Volume: 301, Issue:6

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Kidney; Male; Rats; Rats, Sprague-Dawley; Renin; Tetrazoles

2011
Defective nitric oxide production impairs angiotensin II-induced Na-K-ATPase regulation in spontaneously hypertensive rats.
    American journal of physiology. Renal physiology, 2012, Jan-01, Volume: 302, Issue:1

    Topics: Angiotensin II; Animals; Arginine; Benzimidazoles; Biphenyl Compounds; Kidney Tubules, Proximal; Male; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Sodium-Potassium-Exchanging ATPase; Tetrazoles

2012
Angiotensin II acts through the angiotensin 1a receptor to upregulate pendrin.
    American journal of physiology. Renal physiology, 2011, Volume: 301, Issue:6

    Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Anion Transport Proteins; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Diet, Sodium-Restricted; Female; Hypertension; Male; Mice; Nitric Oxide; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sulfate Transporters; Tetrazoles; Up-Regulation; Vasoconstrictor Agents

2011
Therapeutic effects of postischemic treatment with hypotensive doses of an angiotensin II receptor blocker on transient focal cerebral ischemia.
    Journal of hypertension, 2011, Volume: 29, Issue:11

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Brain; Brain Edema; Brain Ischemia; Hypotension; Ischemia; Rats; Rats, Sprague-Dawley; Tetrazoles; Time Factors

2011
Candesartan restored cardiac Hsp72 expression and tolerance against reperfusion injury in hereditary insulin-resistant rats.
    Cardiovascular research, 2011, Dec-01, Volume: 92, Issue:3

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cells, Cultured; Dietary Fats; Disease Models, Animal; Genetic Predisposition to Disease; Glucose Tolerance Test; Glucose Transporter Type 4; Heredity; HSP72 Heat-Shock Proteins; Hyperthermia, Induced; Insulin Resistance; Male; Myocardial Reperfusion Injury; Myocardium; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Rats; Rats, Inbred OLETF; Rats, Long-Evans; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Recovery of Function; Tetrazoles; Time Factors; Ventricular Function, Left; Ventricular Pressure

2011
Direct renin inhibition in a rat model of chronic allograft injury.
    Transplantation, 2011, Nov-15, Volume: 92, Issue:9

    Topics: Amides; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Fumarates; Kidney; Kidney Transplantation; Male; Models, Animal; Peptide Fragments; Rats; Rats, Inbred F344; Rats, Inbred Lew; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Tetrazoles; Transplantation, Homologous

2011
Angiotensin AT1 receptor blockers suppress oxidized low-density lipoprotein-derived formation of foam cells.
    European journal of pharmacology, 2012, Mar-15, Volume: 679, Issue:1-3

    Topics: Acetyl-CoA C-Acetyltransferase; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Cholesterol Esters; Enzyme Inhibitors; ErbB Receptors; Foam Cells; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Lipoproteins, LDL; Losartan; Macrophages; Quinazolines; Tetrazoles; Triglycerides; Tyrphostins

2012
Angiotensin II regulates growth of the developing papillas ex vivo.
    American journal of physiology. Renal physiology, 2012, May-01, Volume: 302, Issue:9

    Topics: Angiotensin II; Angiotensinogen; Animals; Animals, Newborn; Apoptosis; Benzimidazoles; Biphenyl Compounds; Cell Proliferation; Female; Homeodomain Proteins; Kidney Medulla; Male; Mice; Mice, Knockout; Models, Animal; Morphogenesis; Receptor, Angiotensin, Type 1; Tetrazoles

2012
Effects of tempol and candesartan on neural control of the kidney.
    Autonomic neuroscience : basic & clinical, 2012, May-21, Volume: 168, Issue:1-2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cyclic N-Oxides; Diet; Diet, High-Fat; Dinoprost; Dose-Response Relationship, Drug; Electric Stimulation; Heart Rate; Hematocrit; Kidney; Kidney Function Tests; Male; Obesity; Rabbits; Renal Circulation; Spin Labels; Superoxides; Tetrazoles; Urodynamics

2012
Cardiovascular effects of angiotensin II and glutamate in the PVN of Dahl salt-sensitive rats.
    Brain research, 2012, Apr-04, Volume: 1447

    Topics: Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Glutamic Acid; Heart Rate; Kynurenic Acid; Male; Paraventricular Hypothalamic Nucleus; Rats; Rats, Inbred Dahl; Receptors, Angiotensin; Tetrazoles

2012
Effect of angiotensin II on proliferation and differentiation of mouse induced pluripotent stem cells into mesodermal progenitor cells.
    Biochemical and biophysical research communications, 2012, Mar-30, Volume: 420, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Cell Differentiation; Cell Proliferation; Cells, Cultured; Culture Media; Cyclic N-Oxides; DNA; Induced Pluripotent Stem Cells; Janus Kinases; Leukemia Inhibitory Factor; Mesoderm; Mice; p38 Mitogen-Activated Protein Kinases; Receptor, Angiotensin, Type 1; Spin Labels; STAT3 Transcription Factor; Stem Cells; Tetrazoles

2012
Loss of renal medullary endothelin B receptor function during salt deprivation is regulated by angiotensin II.
    American journal of physiology. Renal physiology, 2012, Volume: 303, Issue:5

    Topics: Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Diet, Sodium-Restricted; Diuresis; Endothelin-1; Endothelin-2; Kidney Medulla; Male; Natriuresis; Rats; Rats, Sprague-Dawley; Receptor, Endothelin B; Sodium Chloride, Dietary; Sodium, Dietary; Tetrazoles; Viper Venoms

2012
Intrarenal angiotensin III is the predominant agonist for proximal tubule angiotensin type 2 receptors.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 60, Issue:2

    Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin III; Animals; Benzimidazoles; Biphenyl Compounds; Female; Imidazoles; Kidney Tubules, Proximal; Models, Animal; Natriuresis; Peptide Fragments; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Tetrazoles

2012
Rapid, dynamic changes in glomerular permeability to macromolecules during systemic angiotensin II (ANG II) infusion in rats.
    American journal of physiology. Renal physiology, 2012, Sep-15, Volume: 303, Issue:6

    Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Ficoll; Glomerular Filtration Rate; Infusions, Intravenous; Kidney Glomerulus; Male; Mineralocorticoid Receptor Antagonists; Nimodipine; Permeability; Rats; Rats, Wistar; Spironolactone; Tetrazoles; Vasodilator Agents

2012
[Studying the influence of Candesartan cilexetil on the lung fibrosis in rats exposed to silica].
    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2012, Volume: 30, Issue:4

    Topics: Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Bronchoalveolar Lavage Fluid; Female; Lung; Male; Pulmonary Fibrosis; Rats; Rats, Wistar; Silicon Dioxide; Tetrazoles; Transforming Growth Factor beta1

2012
Role of angiotensin II in arterial pressure and renal hemodynamics in rats with altered renal development: age- and sex-dependent differences.
    American journal of physiology. Renal physiology, 2013, Jan-01, Volume: 304, Issue:1

    Topics: Aging; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Arterial Pressure; Benzimidazoles; Biphenyl Compounds; Female; Kidney; Male; Mesenteric Arteries; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Sex Characteristics; Tetrazoles

2013
Effect of angiotensin II on spatial memory, cerebral blood flow, cholinergic neurotransmission, and brain derived neurotrophic factor in rats.
    Psychopharmacology, 2013, Volume: 226, Issue:2

    Topics: Acetylcholine; Acetylcholinesterase; Adenosine Triphosphate; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Brain-Derived Neurotrophic Factor; Cerebrovascular Circulation; Cholinesterase Inhibitors; Donepezil; Hippocampus; Imidazoles; Indans; Male; Melatonin; Memory; Oxidative Stress; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Tetrazoles

2013
Direct evidence for intrarenal chymase-dependent angiotensin II formation on the diabetic renal microvasculature.
    Hypertension (Dallas, Tex. : 1979), 2013, Volume: 61, Issue:2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Chymases; Diabetes Mellitus, Type 2; Kidney; Male; Mice; Microvessels; Peptidyl-Dipeptidase A; Tetrazoles

2013
Angiotensin II contributes to glomerular hyperfiltration in diabetic rats independently of adenosine type I receptors.
    American journal of physiology. Renal physiology, 2013, Mar-01, Volume: 304, Issue:5

    Topics: Adenosine A1 Receptor Antagonists; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dose-Response Relationship, Drug; Glomerular Filtration Rate; Kidney; Male; Rats; Receptor, Adenosine A1; Renal Circulation; Tetrazoles; Vascular Resistance; Xanthines

2013
Leukotrienes, but not angiotensin II, are involved in the renal effects elicited by the prolonged cyclooxygenase-2 inhibition when sodium intake is low.
    Journal of cardiovascular pharmacology, 2013, Volume: 61, Issue:4

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzopyrans; Biphenyl Compounds; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diet, Sodium-Restricted; Dogs; Glomerular Filtration Rate; Kidney; Leukotrienes; Lipoxygenase Inhibitors; Pyrans; Pyrazoles; Renal Circulation; Tetrazoles

2013
Cardiovascular and electrocardiographic parameters after tonin administration in Wistar rats.
    Regulatory peptides, 2013, Feb-10, Volume: 181

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Arterial Pressure; Benzimidazoles; Biphenyl Compounds; Calcium; Cells, Cultured; Electrocardiography; Heart; Heart Rate; Heart Ventricles; Male; Myocardial Contraction; Myocytes, Cardiac; Organ Culture Techniques; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Tetrazoles; Tissue Kallikreins

2013
Attenuation of increased secretory leukocyte protease inhibitor, matricellular proteins and angiotensin II and left ventricular remodeling by candesartan and omapatrilat during healing after reperfused myocardial infarction.
    Molecular and cellular biochemistry, 2013, Volume: 376, Issue:1-2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Benzimidazoles; Biphenyl Compounds; Collagen; Male; Myocardial Infarction; Myocardial Reperfusion; Osteonectin; Pyridines; Rats, Sprague-Dawley; Secretory Leukocyte Peptidase Inhibitor; Tetrazoles; Thiazepines; Ventricular Remodeling

2013
Spreading vasodilatation in the murine microcirculation: attenuation by oxidative stress-induced change in electromechanical coupling.
    The Journal of physiology, 2013, Apr-15, Volume: 591, Issue:8

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Arterioles; Benzimidazoles; Biphenyl Compounds; Calcium Channels, L-Type; Calcium Channels, T-Type; Connexins; Endothelium, Vascular; Gap Junction alpha-5 Protein; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microcirculation; Models, Cardiovascular; Oxidative Stress; Renin; Tetrazoles; Vasodilation

2013
Improvement of the antihypertensive capacity of candesartan and trityl candesartan by their SOD mimetic copper(II) complexes.
    Journal of inorganic biochemistry, 2013, Volume: 123

    Topics: Angiotensin II; Antihypertensive Agents; Antioxidants; Benzimidazoles; Biphenyl Compounds; Copper; Humans; Mesangial Cells; Molecular Structure; Spectroscopy, Fourier Transform Infrared; Superoxide Dismutase; Tetrazoles

2013
Central mineralocorticoid receptors and the role of angiotensin II and glutamate in the paraventricular nucleus of rats with angiotensin II-induced hypertension.
    Hypertension (Dallas, Tex. : 1979), 2013, Volume: 61, Issue:5

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Disease Models, Animal; Eplerenone; Glutamic Acid; Heart Rate; Hypertension; Infusions, Intravenous; Infusions, Intraventricular; Kynurenic Acid; Male; Mineralocorticoid Receptor Antagonists; Paraventricular Hypothalamic Nucleus; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Glutamate; Receptors, Mineralocorticoid; Signal Transduction; Spironolactone; Tetrazoles

2013
Angiotensin II modulates salty and sweet taste sensitivities.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, Apr-10, Volume: 33, Issue:15

    Topics: Aldosterone; Amiloride; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Chorda Tympani Nerve; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Female; Food Preferences; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Plasma; Receptor, Angiotensin, Type 2; Receptor, Cannabinoid, CB1; Receptors, G-Protein-Coupled; Taste; Taste Buds; Taste Perception; Tetrazoles; TRPM Cation Channels

2013
Microglial TNF-α mediates enhancement of dopaminergic degeneration by brain angiotensin.
    Glia, 2014, Volume: 62, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Cyclic CMP; Dopaminergic Neurons; Dose-Response Relationship, Drug; Enzyme Inhibitors; Kallikreins; Male; Mesencephalon; Mice; Mice, Inbred C57BL; Microglia; Nerve Degeneration; Neurons; Neurotoxins; Pancreatic Extracts; Tetrazoles; Tumor Necrosis Factor-alpha

2014
Female spontaneously hypertensive rats are more dependent on ANG (1-7) to mediate effects of low-dose AT1 receptor blockade than males.
    American journal of physiology. Renal physiology, 2014, May-15, Volume: 306, Issue:10

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cell Adhesion Molecules; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hypertension; Male; Membrane Proteins; Peptide Fragments; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Sex Factors; Tetrazoles

2014
Oxidative DNA damage in kidneys and heart of hypertensive mice is prevented by blocking angiotensin II and aldosterone receptors.
    PloS one, 2014, Volume: 9, Issue:12

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cyclic N-Oxides; Deoxyguanosine; DNA Damage; DNA Repair; Enzyme Activation; Eplerenone; Guanosine; Heart; Hypertension; Kidney; Male; Mice; Mice, Inbred C57BL; Mineralocorticoid Receptor Antagonists; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Reactive Oxygen Species; Renin-Angiotensin System; Spin Labels; Spironolactone; Tetrazoles

2014
Suppression of adrenal βarrestin1-dependent aldosterone production by ARBs: head-to-head comparison.
    Scientific reports, 2015, Jan-29, Volume: 5

    Topics: Adrenal Glands; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arrestins; Benzimidazoles; beta-Arrestins; Biphenyl Compounds; CHO Cells; Cricetinae; Cricetulus; GTP-Binding Proteins; Humans; Phosphoproteins; Rats; Receptor, Angiotensin, Type 1; Tetrazoles; Up-Regulation; Valine; Valsartan; Zona Glomerulosa

2015
Candesartan attenuates angiogenesis in hepatocellular carcinoma via downregulating AT1R/VEGF pathway.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 83

    Topics: Angiogenesis Inhibitors; Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Humans; Liver Neoplasms; Mice, Nude; Neovascularization, Pathologic; Receptor, Angiotensin, Type 1; Tetrazoles; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays

2016
Angiotensin type 1A receptor regulates β-arrestin binding of the β
    Molecular and cellular endocrinology, 2017, 02-15, Volume: 442

    Topics: Angiotensin II; Animals; Benzimidazoles; beta-Arrestins; Biphenyl Compounds; Cell Line; Cell Membrane; Chlorocebus aethiops; CHO Cells; COS Cells; Cricetulus; Dimerization; GTP-Binding Proteins; HEK293 Cells; Humans; Oligopeptides; Protein Binding; Receptor, Angiotensin, Type 1; Receptors, Adrenergic, beta-2; Signal Transduction; Tetrazoles

2017
Glucagon increase after chronic AT
    Naunyn-Schmiedeberg's archives of pharmacology, 2017, Volume: 390, Issue:5

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Biphenyl Compounds; Cell Line; Dose-Response Relationship, Drug; Glucagon; Hypoglycemic Agents; Islets of Langerhans; Leptin; Male; Mice, Inbred C57BL; Rats, Sprague-Dawley; Rats, Zucker; Receptor, Angiotensin, Type 1; Telmisartan; Tetrazoles; Time Factors; Up-Regulation

2017
β-Arrestin-biased AT1R stimulation promotes extracellular matrix synthesis in renal fibrosis.
    American journal of physiology. Renal physiology, 2017, 07-01, Volume: 313, Issue:1

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; beta-Arrestin 1; beta-Arrestin 2; Biphenyl Compounds; Cell Line; Collagen Type I; Disease Models, Animal; Extracellular Matrix; Fibroblasts; Fibronectins; Fibrosis; Kidney; Kidney Diseases; Male; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Rats; Receptor, Angiotensin, Type 1; RNA Interference; Signal Transduction; Tetrazoles; Time Factors; Transfection; Ureteral Obstruction

2017
Impact of Aldosterone Synthase Inhibitor FAD286 on Steroid Hormone Profile in Human Adrenocortical Cells.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2017, Volume: 49, Issue:9

    Topics: Adrenal Cortex; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Cell Line; Cytochrome P-450 CYP11B2; Enzyme Inhibitors; Fadrozole; Gene Expression Regulation, Enzymologic; Glucocorticoids; Hormones; Humans; Receptor, Angiotensin, Type 1; RNA, Messenger; Steroids; Tetrazoles

2017
Augmented sphingosine 1 phosphate receptor-1 signaling in cardiac fibroblasts induces cardiac hypertrophy and fibrosis through angiotensin II and interleukin-6.
    PloS one, 2017, Volume: 12, Issue:8

    Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Cardiomegaly; Cells, Cultured; Fibroblasts; Heart Ventricles; Humans; Interleukin-6; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocardium; Myocytes, Cardiac; Peptidyl-Dipeptidase A; Phosphorylation; Plasmids; Receptors, Lysosphingolipid; Signal Transduction; Tetrazoles

2017
Candesartan prevents resiniferatoxin-induced sensory small-fiber neuropathy in mice by promoting angiotensin II-mediated AT2 receptor stimulation.
    Neuropharmacology, 2017, Volume: 126

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Calcitonin Gene-Related Peptide; Diterpenes; Ganglia, Spinal; Imidazoles; Male; Mice; Mice, Knockout; Neuroprotective Agents; Pyridines; Ramipril; Receptor, Angiotensin, Type 2; Sensory Receptor Cells; Small Fiber Neuropathy; Substance P; Tetrazoles

2017
    Journal of the American Society of Nephrology : JASN, 2018, Volume: 29, Issue:1

    Topics: Actins; Albuminuria; Angiotensin II; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cell Movement; Cells, Cultured; Disease Models, Animal; Genotype; Hypertension; Male; Mice; Mutation, Missense; Myosin Heavy Chains; Nephrectomy; Nonmuscle Myosin Type IIA; Podocytes; Primary Cell Culture; Renal Insufficiency, Chronic; Sodium Chloride, Dietary; Stress Fibers; Tetrazoles

2018
Ultrasound-Stimulated Microbubbles Enhance Radiosensitization of Nasopharyngeal Carcinoma.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 48, Issue:4

    Topics: Angiotensin II; Animals; Antigens, CD34; Benzimidazoles; Biphenyl Compounds; Carcinoma; Cell Line, Tumor; Cell Proliferation; Cell Survival; Contrast Media; Female; Gamma Rays; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Nude; Microbubbles; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Perindopril; Receptor, Angiotensin, Type 1; Sonication; Tetrazoles

2018
Angiotensin II upregulates CYP4A isoform expression in the rat kidney through angiotensin II type 1 receptor.
    Prostaglandins & other lipid mediators, 2018, Volume: 139

    Topics: Angiotensin II; Animals; Arachidonic Acid; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cytochrome P-450 CYP4A; Disease Models, Animal; Gene Expression Regulation; Humans; Hydroxyeicosatetraenoic Acids; Hypertension; Kidney; Protein Isoforms; Rats; Receptor, Angiotensin, Type 1; RNA, Messenger; Tetrazoles

2018
[Candesartan inhibits the angiotensin II-induced proliferation and migration of rat thoracic aortic smooth muscle A7r5 cells and its mechanism].
    Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2019, Volume: 35, Issue:2

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cell Line; Cell Movement; Cell Proliferation; Muscle, Smooth, Vascular; Rats; Tetrazoles

2019
ACE (Angiotensin-Converting Enzyme) Inhibition Reverses Vasoconstriction and Impaired Dilation of Pial Collaterals in Chronic Hypertension.
    Hypertension (Dallas, Tex. : 1979), 2020, Volume: 76, Issue:1

    Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Captopril; Chronic Disease; Collateral Circulation; Hydralazine; Hypertension; Male; Pia Mater; Random Allocation; Rats; Rats, Inbred SHR; Rats, Wistar; Receptor, Angiotensin, Type 1; rho-Associated Kinases; Tetrazoles; Vasoconstriction; Vasodilator Agents; Vasomotor System

2020
Maternal Angiotensin Increases Placental Leptin in Early Gestation via an Alternative Renin-Angiotensin System Pathway: Suggesting a Link to Preeclampsia.
    Hypertension (Dallas, Tex. : 1979), 2021, 05-05, Volume: 77, Issue:5

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensins; Benzimidazoles; Biphenyl Compounds; Female; Humans; Leptin; Leucyl Aminopeptidase; Placenta; Pre-Eclampsia; Pregnancy; Renin-Angiotensin System; Tetrazoles; Uterine Artery; Vascular Resistance

2021
Autophagy contributes to angiotensin II induced dysfunction of HUVECs.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2021, Jul-04, Volume: 43, Issue:5

    Topics: Acetophenones; Adenine; Angiotensin II; Animals; Autophagosomes; Autophagy; Autophagy-Related Proteins; Benzimidazoles; Biphenyl Compounds; Decanoic Acids; Human Umbilical Vein Endothelial Cells; Humans; Hydroxy Acids; Models, Biological; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Signal Transduction; Sirolimus; Tetrazoles; Time Factors

2021
AT II Receptor Blockade and Renal Denervation: Different Interventions with Comparable Renal Effects?
    Kidney & blood pressure research, 2021, Volume: 46, Issue:3

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Arterial Pressure; Benzimidazoles; Biphenyl Compounds; Denervation; Glomerular Filtration Rate; Heart Rate; Kidney; Male; Rats, Sprague-Dawley; Sodium; Tetrazoles; Water

2021
Angiotensin II Disrupts Neurovascular Coupling by Potentiating Calcium Increases in Astrocytic Endfeet.
    Journal of the American Heart Association, 2021, 09-07, Volume: 10, Issue:17

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Astrocytes; Benzimidazoles; Biphenyl Compounds; Calcium; Calcium Signaling; Cerebrovascular Circulation; Male; Mice, Inbred C57BL; Neurovascular Coupling; Receptor, Angiotensin, Type 1; Tetrazoles; Vasoconstriction

2021
Candesartan Protects Against Cadmium-Induced Hepatorenal Syndrome by Affecting Nrf2, NF-κB, Bax/Bcl-2/Cyt-C, and Ang II/Ang 1-7 Signals.
    Biological trace element research, 2023, Volume: 201, Issue:4

    Topics: Angiotensin II; bcl-2-Associated X Protein; Cadmium; Hepatorenal Syndrome; Humans; NF-E2-Related Factor 2; NF-kappa B

2023
Candesartan Does Not Activate PPARγ and Its Target Genes in Early Gestation Trophoblasts.
    International journal of molecular sciences, 2022, Oct-14, Volume: 23, Issue:20

    Topics: Angiotensin II; Female; Humans; Placenta; Placentation; PPAR gamma; Pregnancy; Receptor, Angiotensin, Type 1; Rosiglitazone; Trophoblasts

2022
Paeonol improves renal and vascular angiotensin II type 1 receptor function via inhibiting oxidative stress in spontaneously hypertensive rats.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2023, Dec-31, Volume: 45, Issue:1

    Topics: Angiotensin II; Animals; Hypertension; Kidney; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Renin; Vasoconstrictor Agents

2023