candesartan and aldosterone

candesartan has been researched along with aldosterone in 41 studies

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (4.88)18.2507
2000's26 (63.41)29.6817
2010's13 (31.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Inada, Y; Nishikawa, K; Noda, M; Ojima, M; Sanada, T; Shibouta, Y; Wada, T1
Arai, K; Demura, H; Imaki, T; Kobayashi, M; Miyazaki, H; Naruse, K; Naruse, M; Seki, T; Tanabe, A; Yoshimoto, T1
Grossman, E; Messerli, FH; Neutel, JM1
Beutler, K; Knepper, MA; Masilamani, S; Nielsen, J; Nielsen, S; Wang, XY1
Belz, GG; Butzer, R; Kober, S; Mutschler, E1
Dietz, R; Mitrovic, V; Philipp, S; Willenbrock, R1
Andersson, OK; Elmfeldt, D; Friberg, PR; Fridman, KU; Wysocki, M1
Fukuda, N; Onose, Y; Sakabe, K; Shinohara, H; Soeki, T; Tamura, Y1
de Boer, RA; de Borst, MH; Huitema, S; Navis, G; van Gilst, WH; van Goor, H; Vis, LM1
Anzai, T; Hashimoto, K; Himeno, H; Imai, K; Kawana, M; Kitakaze, M; Koretsune, Y; Maruyama, S; Masaoka, Y; Matsubara, H; Matsuoka, T; Miyao, Y; Miyatake, K; Miyauchi, T; Nakamura, Y; Nomura, F; Okamoto, H; Ozono, K; Sekiya, M; Shinohara, H; Shintani, U; Shiraki, T; Takaoka, H; Tsutamoto, T; Yasumura, Y; Yokoya, K; Yokoyama, H1
Agarwal, A; Fisher, ND; Hollenberg, NK; Laffel, LM; Lansang, MC; Price, DA; Stevanovic, R; Williams, GH1
Hara, Y; Imaki, T; Naruse, M; Nishikawa, T; Sato, A; Takano, K; Tanabe, A; Tsuchiya, K1
Ando, T; Itoh, M; Joh, T; Kuno, A; Masuda, K; Nakamura, S; Nomura, T; Ogawa, K; Ohara, H; Okamoto, T; Shirai, T; Tang, M; Yamada, T1
Ichikawa, S; Kurabayashi, M; Miya, Y; Sakamaki, T; Sumino, H1
Date, T; Kawai, M; Mochizuki, S; Seki, S; Shimizu, M; Taniguchi, I; Taniguchi, M; Yoshida, S1
Bonventre, JV; de Boer, RA; de Borst, MH; Kramer, AB; Navis, G; Schuurs, TA; Vaidya, VS; van Dalen, MB; van Goor, H; van Timmeren, MM1
Bie, P; Gammelgaard, I; Wamberg, S1
Djurhuus, JC; Frøkiaer, J; Jørgensen, TM; Knepper, M; Nielsen, S; Nørregaard, R; Pedersen, M; Topcu, SO; Wang, G1
Hirata, Y; Hirono, Y; Kobayashi, N; Sakurada, M; Shichiri, M; Sugiyama, T; Suzuki, N; Takai, S; Yoshimoto, T1
Briggs, JP; Chen, L; Faulhaber-Walter, R; Huang, Y; Kim, SM; Mizel, D; Oppermann, M; Schnermann, J1
Takata, H; Takeda, Y; Usukura, M; Yamagishi, M; Yoneda, T; Zhu, A1
Karashima, S; Oda, N; Takata, H; Takeda, Y; Usukura, M; Yamagishi, M; Yamamoto, Y; Yoneda, T1
Goto, J; Inagaki, K; Kano, Y; Makino, H; Miyoshi, T; Ogura, T; Otani, H; Otsuka, F; Suzuki, J1
Kushibiki, M; Okumura, K; Osanai, T; Tomita, H; Yamada, M1
Larrayoz-Roldan, IM; Moughamian, AJ; Murakami, Y; Nishioku, T; Pavel, J; Saavedra, JM; Sanchez-Lemus, E1
Hayashi, K; Ishiguro, K; Itoh, H; Sakamaki, Y; Sasamura, H1
Afzal, R; Floras, J; McKelvie, RS; Rouleau, JL; White, M; Yusuf, S1
Homma, I; Iigaya, K; Kobayashi, Y; Minoura, Y; Onimaru, H1
Fujii, M; Horie, M; Kawahara, C; Nishiyama, K; Tsutamoto, T; Yamaji, M; Yamamoto, T1
Arun, SN; Bollag, WB; George, MV; Olala, L; Parker, PM; Shapiro, BA1
Hata, M; Sezai, A; Shiono, M; Soma, M; Unosawa, S; Wakui, S; Yoshitake, I1
Agazatian, D; Bailey, JL; Coffman, TM; Farley, DB; Hong, S; Inagami, T; Kim, YH; Le, T; Matthews, SW; Pech, V; Verlander, JW; Wall, SM; Weiner, ID; Whitehill, FM1
Fujita, T; Hirooka, K; Itano, T; Lei, B; Liu, Y; Nakamura, T; Nishiyama, A; Shiraga, F; Zhang, J1
Briones, AM; Burger, D; Burns, KD; Callera, GE; Corrêa, JW; Gagnon, AM; Gomez-Sanchez, CE; Gomez-Sanchez, EP; He, Y; Nguyen Dinh Cat, A; Ooi, TC; Ruzicka, M; Sorisky, A; Touyz, RM; Yogi, A1
Axelsson, J; Oberg, CM; Rippe, A; Rippe, B1
Horio, N; Iwata, S; Margolskee, RF; Ninomiya, Y; Ohkuri, T; Sanematsu, K; Shigemura, N; Yasumatsu, K; Yoshida, R1
Boomsma, F; Danser, AH; Schilders, JE; van den Meiracker, AH; Wu, H1
Bathgate-Siryk, A; Dabul, S; Garcia, D; Koch, WJ; Lymperopoulos, A; McDonald, P; Rengo, G; Sturchler, E; Walklett, K1
Amann, K; Brand, S; Mandel, P; Schupp, N; Zimnol, A1
Bathgate-Siryk, A; Dabul, S; Jafferjee, M; Koch, WJ; Lymperopoulos, A; McDonald, P; Sturchler, E; Valero, TR1
Bornstein, SR; Brown, NF; Brunssen, C; Eisenhofer, G; Frenzel, A; Hofmann, A; Morawietz, H; Peitzsch, M; Weldon, SM; Willenberg, HS; Ziegler, CG1

Reviews

2 review(s) available for candesartan and aldosterone

ArticleYear
Angiotensin II receptor blockers: equal or preferred substitutes for ACE inhibitors?
    Archives of internal medicine, 2000, Jul-10, Volume: 160, Issue:13

    Topics: Acrylates; Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Drug Therapy, Combination; Heart; Humans; Hypertension; Imidazoles; Irbesartan; Kidney; Losartan; Renin-Angiotensin System; Telmisartan; Tetrazoles; Thiophenes

2000
Neurohumoral blockade in CHF management.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2000, Volume: 1 Suppl 1

    Topics: Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Heart Failure; Hormone Antagonists; Humans; Mineralocorticoid Receptor Antagonists; Neurotransmitter Agents; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Tetrazoles

2000

Trials

10 trial(s) available for candesartan and aldosterone

ArticleYear
Pharmacodynamic studies on the angiotensin II type 1 antagonists irbesartan and candesartan based on angiotensin II dose response in humans.
    Journal of cardiovascular pharmacology, 2002, Volume: 39, Issue:4

    Topics: Adult; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Half-Life; Humans; Irbesartan; Male; Radioligand Assay; Receptor, Angiotensin, Type 1; Renin; Tetrazoles

2002
Influence of AT1 receptor blockade on blood pressure, renal haemodynamics and hormonal responses to intravenous angiotensin II infusion in hypertensive patients.
    Blood pressure, 2002, Volume: 11, Issue:4

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hypertension; Infusions, Intravenous; Losartan; Male; Middle Aged; Receptor, Angiotensin, Type 1; Renal Circulation; Renin; Tetrazoles; Valine; Valsartan

2002
Rationale for the use of combination angiotensin-converting enzyme inhibitor and angiotensin II receptor blocker therapy in heart failure.
    Circulation journal : official journal of the Japanese Circulation Society, 2004, Volume: 68, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Drug Synergism; Drug Therapy, Combination; Exercise Tolerance; Female; Heart Failure; Heart Function Tests; Humans; Losartan; Male; Middle Aged; Natriuretic Peptide, Brain; Receptors, Angiotensin; Renin; Tetrazoles; Valine; Valsartan

2004
Angiotensin II plays an important role in maintaining blood pressure in postmenopausal women receiving hormone replacement therapy.
    American journal of hypertension, 2005, Volume: 18, Issue:10

    Topics: Administration, Oral; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biomarkers; Biphenyl Compounds; Blood Pressure; Bradykinin; Drug Therapy, Combination; Epinephrine; Estrogens; Female; Heart Rate; Hormone Replacement Therapy; Humans; Middle Aged; Norepinephrine; Peptidyl-Dipeptidase A; Postmenopause; Renin; Tetrazoles; Treatment Outcome

2005
Effects of spironolactone during an angiotensin II receptor blocker treatment on the left ventricular mass reduction in hypertensive patients with concentric left ventricular hypertrophy.
    Circulation journal : official journal of the Japanese Circulation Society, 2006, Volume: 70, Issue:8

    Topics: Aged; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Echocardiography; Female; Heart Ventricles; Hemodynamics; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Natriuretic Peptide, Brain; Spironolactone; Tetrazoles; Ventricular Remodeling

2006
Aldosterone breakthrough during angiotensin II receptor blockade in hypertensive patients with diabetes mellitus.
    American journal of hypertension, 2007, Volume: 20, Issue:12

    Topics: Aged; Albuminuria; Aldosterone; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan

2007
Effects of enalapril, candesartan or both on neurohumoral activation and LV volumes and function in patients with heart failure not treated with a beta-blocker.
    Therapeutic advances in cardiovascular disease, 2009, Volume: 3, Issue:2

    Topics: Aged; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Double-Blind Method; Drug Therapy, Combination; Enalapril; Endothelin-1; Female; Heart Failure; Humans; Male; Middle Aged; Natriuretic Peptide, Brain; Norepinephrine; Peptide Fragments; Radionuclide Angiography; Stroke Volume; Tetrazoles; Treatment Outcome; Ventricular Function, Left

2009
Comparison of the long-term effects of candesartan and olmesartan on plasma angiotensin II and left ventricular mass index in patients with hypertension.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2010, Volume: 33, Issue:2

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Male; Middle Aged; Natriuretic Peptide, Brain; Peptidyl-Dipeptidase A; Tetrazoles

2010
Effects of olmesartan on the renin-angiotensin-aldosterone system for patients with essential hypertension after cardiac surgery--investigation using a candesartan change-over study.
    Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 2011, Volume: 17, Issue:5

    Topics: Aged; Aldosterone; Analysis of Variance; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Arteries; Benzimidazoles; Biphenyl Compounds; Cardiac Surgical Procedures; Compliance; Drug Substitution; Female; Hemodynamics; Humans; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Japan; Male; Middle Aged; Prospective Studies; Renin; Renin-Angiotensin System; Tetrazoles; Time Factors; Treatment Outcome

2011
Renin-angiotensin system phenotyping as a guidance toward personalized medicine for ACE inhibitors: can the response to ACE inhibition be predicted on the basis of plasma renin or ACE?
    Cardiovascular drugs and therapy, 2014, Volume: 28, Issue:4

    Topics: Aged; Aldosterone; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cross-Over Studies; Diuretics; Double-Blind Method; Drug Therapy, Combination; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Peptidyl-Dipeptidase A; Phenotype; Precision Medicine; Renin; Renin-Angiotensin System; Tetrazoles

2014

Other Studies

29 other study(ies) available for candesartan and aldosterone

ArticleYear
Effect of an angiotensin II receptor antagonist, CV-11974, and its prodrug, TCV-116, on production of aldosterone.
    European journal of pharmacology, 1994, Feb-21, Volume: 253, Issue:1-2

    Topics: Administration, Oral; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Corticosterone; Hypertension; Imidazoles; Infusions, Intravenous; Male; Pyridines; Rabbits; Rats; Rats, Inbred SHR; Rats, Wistar; Tetrazoles; Zona Glomerulosa

1994
Angiotensin II stimulates both aldosterone secretion and DNA synthesis via type 1 but not type 2 receptors in bovine adrenocortical cells.
    Journal of endocrinological investigation, 1998, Volume: 21, Issue:10

    Topics: Adrenal Cortex; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Cattle; Cells, Cultured; DNA; Imidazoles; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Zona Glomerulosa

1998
Decreased abundance of collecting duct urea transporters UT-A1 and UT-A3 with ECF volume expansion.
    American journal of physiology. Renal physiology, 2002, Volume: 282, Issue:4

    Topics: Aldosterone; Angiotensin Receptor Antagonists; Animals; Aquaporins; Benzimidazoles; Biphenyl Compounds; Carrier Proteins; Diet; Extracellular Space; Immunoblotting; Immunohistochemistry; Kidney Tubules, Collecting; Male; Membrane Glycoproteins; Membrane Transport Proteins; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Tetrazoles; Urea; Urea Transporters

2002
Effects of angiotensin II receptor antagonists on [(123)I]metaiodobenzylguanidine myocardial imaging findings and neurohumoral factors in chronic heart failure.
    Heart and vessels, 2002, Volume: 17, Issue:2

    Topics: 3-Iodobenzylguanidine; Aged; Aged, 80 and over; Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atrial Natriuretic Factor; Benzimidazoles; Biomarkers; Biphenyl Compounds; Blood Pressure; Creatinine; Echocardiography; Female; Heart; Heart Failure; Humans; Losartan; Male; Middle Aged; Natriuretic Peptide, Brain; Neurotransmitter Agents; Norepinephrine; Potassium; Radionuclide Imaging; Radiopharmaceuticals; Receptors, Angiotensin; Renin; Severity of Illness Index; Statistics as Topic; Stroke Volume; Tetrazoles; Time Factors; Treatment Outcome; Ventricular Dysfunction, Left

2002
Specific MAP-kinase blockade protects against renal damage in homozygous TGR(mRen2)27 rats.
    Laboratory investigation; a journal of technical methods and pathology, 2003, Volume: 83, Issue:12

    Topics: Actins; Aldosterone; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Genetically Modified; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Desmin; Enzyme Inhibitors; Glomerular Mesangium; Homozygote; Imidazoles; Kidney Diseases; Male; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Pyrimidines; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger; Tetrazoles; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tyrphostins

2003
Plasma aldosterone concentration in the patient with diabetes mellitus.
    Kidney international, 2004, Volume: 65, Issue:4

    Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Case-Control Studies; Diabetes Mellitus, Type 1; Female; Humans; Male; Middle Aged; Osmolar Concentration; Renin; Tetrazoles

2004
Aldosterone antagonist facilitates the cardioprotective effects of angiotensin receptor blockers in hypertensive rats.
    Journal of hypertension, 2004, Volume: 22, Issue:5

    Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Body Weight; Cardiomegaly; Cardiotonic Agents; Collagen Type I; Collagen Type III; Drug Synergism; Fibrosis; Hypertension; Male; Mineralocorticoid Receptor Antagonists; Myocardium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; RNA, Messenger; Spironolactone; Tetrazoles

2004
Combination therapy with an angiotensin-converting enzyme inhibitor and an angiotensin II receptor blocker synergistically suppresses chronic pancreatitis in rats.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 313, Issue:1

    Topics: Actins; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Body Weight; Chronic Disease; Cytokines; Dose-Response Relationship, Drug; Drug Synergism; Fibrosis; Genes, ras; Hydroxyproline; Immunohistochemistry; Lisinopril; Male; Organ Size; Pancreatitis; Peptidyl-Dipeptidase A; Peroxidase; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; RNA, Messenger; Tetrazoles

2005
Induction of kidney injury molecule-1 in homozygous Ren2 rats is attenuated by blockade of the renin-angiotensin system or p38 MAP kinase.
    American journal of physiology. Renal physiology, 2007, Volume: 292, Issue:1

    Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Genetically Modified; Atrial Natriuretic Factor; Benzimidazoles; Biomarkers; Biphenyl Compounds; Blood Pressure; Cell Adhesion Molecules; Creatinine; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Fibrosis; Immunohistochemistry; Male; Membrane Proteins; Nephritis, Interstitial; Osteopontin; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Inbred Strains; Renin; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; Tetrazoles

2007
Systemic effects of angiotensin III in conscious dogs during acute double blockade of the renin-angiotensin-aldosterone-system.
    Acta physiologica (Oxford, England), 2006, Volume: 188, Issue:2

    Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin III; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Natriuretic Factor; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Enalaprilat; Female; Glomerular Filtration Rate; Metabolic Clearance Rate; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Tetrazoles

2006
Candesartan prevents long-term impairment of renal function in response to neonatal partial unilateral ureteral obstruction.
    American journal of physiology. Renal physiology, 2007, Volume: 292, Issue:2

    Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Aquaporin 2; Benzimidazoles; Biphenyl Compounds; Down-Regulation; Glomerular Filtration Rate; Hydronephrosis; Kidney Failure, Chronic; NF-kappa B; Rats; Renal Circulation; Sodium; Sodium-Potassium-Exchanging ATPase; Tetrazoles; Ureteral Obstruction

2007
Angiotensin II receptor type 1-mediated vascular oxidative stress and proinflammatory gene expression in aldosterone-induced hypertension: the possible role of local renin-angiotensin system.
    Endocrinology, 2007, Volume: 148, Issue:4

    Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Benzimidazoles; Biphenyl Compounds; Blood Vessels; Cyclic N-Oxides; Eplerenone; Gene Expression Regulation; Hypertension; Inflammation Mediators; Male; Models, Biological; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Spin Labels; Spironolactone; Tetrazoles

2007
Regulation of renin secretion and expression in mice deficient in beta1- and beta2-adrenergic receptors.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 50, Issue:1

    Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Captopril; Dose-Response Relationship, Drug; Furosemide; Mice; Mice, Knockout; Osmolar Concentration; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Renin; RNA, Messenger; Sodium Chloride, Dietary; Tetrahydroisoquinolines; Tetrazoles

2007
Effects of aldosterone and angiotensin II receptor blockade on cardiac angiotensinogen and angiotensin-converting enzyme 2 expression in Dahl salt-sensitive hypertensive rats.
    American journal of hypertension, 2007, Volume: 20, Issue:10

    Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Angiotensinogen; Animals; Benzimidazoles; Biphenyl Compounds; Cardiomegaly; Endothelium, Vascular; Eplerenone; Fibrosis; Hypertension; Male; Mineralocorticoid Receptor Antagonists; Myocardium; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Dahl; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; RNA, Messenger; Spironolactone; Tetrazoles

2007
Aldosterone breakthrough caused by chronic blockage of angiotensin II type 1 receptors in human adrenocortical cells: possible involvement of bone morphogenetic protein-6 actions.
    Endocrinology, 2008, Volume: 149, Issue:6

    Topics: Adrenal Cortex; Aldosterone; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Bone Morphogenetic Protein 6; Bone Morphogenetic Proteins; Cell Line; Genes, Reporter; Humans; Immunohistochemistry; Kinetics; Receptor, Angiotensin, Type 1; Reverse Transcriptase Polymerase Chain Reaction; Tetrazoles; Transfection

2008
Vasoconstrictor effect of aldosterone via angiotensin II type 1 (AT1) receptor: possible role of AT1 receptor dimerization.
    Cardiovascular research, 2008, Jul-01, Volume: 79, Issue:1

    Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Animals; Arterioles; Benzimidazoles; Biphenyl Compounds; Dimerization; Eplerenone; Male; Mesentery; Mice; Mice, Inbred C57BL; Mice, Knockout; Mineralocorticoid Receptor Antagonists; Receptor, Angiotensin, Type 1; Spironolactone; Tetrazoles; Transglutaminases; Valine; Valsartan; Vasoconstriction; Vasodilation

2008
Angiotensin II AT1 receptor blockade decreases lipopolysaccharide-induced inflammation in the rat adrenal gland.
    Endocrinology, 2008, Volume: 149, Issue:10

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biomarkers; Biphenyl Compounds; Blood Pressure; Corticosterone; Inflammation; Interleukin-6; Lipopolysaccharide Receptors; Lipopolysaccharides; Male; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Tetrazoles; Tumor Necrosis Factor-alpha

2008
"Pulse" treatment with high-dose angiotensin blocker reverses renal arteriolar hypertrophy and regresses hypertension.
    Hypertension (Dallas, Tex. : 1979), 2009, Volume: 53, Issue:1

    Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Arterioles; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Disease Models, Animal; Dose-Response Relationship, Drug; Enalapril; Hydralazine; Hypertension; Hypertrophy; Kidney; Male; Matrix Metalloproteinase 13; Nifedipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; Tetrazoles; Vasodilator Agents

2009
Electrophysiological responses of sympathetic preganglionic neurons to ANG II and aldosterone.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 297, Issue:3

    Topics: Aldosterone; Anesthetics, Local; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Autonomic Fibers, Preganglionic; Benzimidazoles; Biphenyl Compounds; Eplerenone; Excitatory Postsynaptic Potentials; Female; In Vitro Techniques; Male; Mineralocorticoid Receptor Antagonists; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Rats, Wistar; Spironolactone; Synaptic Transmission; Tetrazoles; Tetrodotoxin; Time Factors

2009
Angiotensin II-activated protein kinase D mediates acute aldosterone secretion.
    Molecular and cellular endocrinology, 2010, Apr-12, Volume: 317, Issue:1-2

    Topics: Adenoviridae; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Cattle; Enzyme Activation; Imidazoles; Mutant Proteins; Potassium; Protein Kinase C; Pyridines; Receptor, Angiotensin, Type 1; Tetradecanoylphorbol Acetate; Tetrazoles; Time Factors; Zona Glomerulosa

2010
Angiotensin II acts through the angiotensin 1a receptor to upregulate pendrin.
    American journal of physiology. Renal physiology, 2011, Volume: 301, Issue:6

    Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Anion Transport Proteins; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Diet, Sodium-Restricted; Female; Hypertension; Male; Mice; Nitric Oxide; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sulfate Transporters; Tetrazoles; Up-Regulation; Vasoconstrictor Agents

2011
Activation of the aldosterone/mineralocorticoid receptor system and protective effects of mineralocorticoid receptor antagonism in retinal ischemia-reperfusion injury.
    Experimental eye research, 2012, Volume: 96, Issue:1

    Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Cell Survival; Male; Mineralocorticoid Receptor Antagonists; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Reperfusion Injury; Retinal Diseases; Spironolactone; Tetrazoles

2012
Adipocytes produce aldosterone through calcineurin-dependent signaling pathways: implications in diabetes mellitus-associated obesity and vascular dysfunction.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 59, Issue:5

    Topics: Adipocytes; Aldosterone; Animals; Benzimidazoles; Biphenyl Compounds; Calcineurin; Cells, Cultured; Diabetes Complications; Diabetic Angiopathies; Disease Models, Animal; Humans; Mice; Mice, Inbred C57BL; Obesity; Random Allocation; Sensitivity and Specificity; Signal Transduction; Tetrazoles

2012
Rapid, dynamic changes in glomerular permeability to macromolecules during systemic angiotensin II (ANG II) infusion in rats.
    American journal of physiology. Renal physiology, 2012, Sep-15, Volume: 303, Issue:6

    Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Ficoll; Glomerular Filtration Rate; Infusions, Intravenous; Kidney Glomerulus; Male; Mineralocorticoid Receptor Antagonists; Nimodipine; Permeability; Rats; Rats, Wistar; Spironolactone; Tetrazoles; Vasodilator Agents

2012
Angiotensin II modulates salty and sweet taste sensitivities.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, Apr-10, Volume: 33, Issue:15

    Topics: Aldosterone; Amiloride; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Chorda Tympani Nerve; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Female; Food Preferences; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Plasma; Receptor, Angiotensin, Type 2; Receptor, Cannabinoid, CB1; Receptors, G-Protein-Coupled; Taste; Taste Buds; Taste Perception; Tetrazoles; TRPM Cation Channels

2013
Different potencies of angiotensin receptor blockers at suppressing adrenal β-Arrestin1-dependent post-myocardial infarction hyperaldosteronism.
    Journal of the American College of Cardiology, 2014, Dec-30, Volume: 64, Issue:25

    Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Hyperaldosteronism; Myocardial Infarction; Rats; Tetrazoles; Valine; Valsartan

2014
Oxidative DNA damage in kidneys and heart of hypertensive mice is prevented by blocking angiotensin II and aldosterone receptors.
    PloS one, 2014, Volume: 9, Issue:12

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cyclic N-Oxides; Deoxyguanosine; DNA Damage; DNA Repair; Enzyme Activation; Eplerenone; Guanosine; Heart; Hypertension; Kidney; Male; Mice; Mice, Inbred C57BL; Mineralocorticoid Receptor Antagonists; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Reactive Oxygen Species; Renin-Angiotensin System; Spin Labels; Spironolactone; Tetrazoles

2014
Suppression of adrenal βarrestin1-dependent aldosterone production by ARBs: head-to-head comparison.
    Scientific reports, 2015, Jan-29, Volume: 5

    Topics: Adrenal Glands; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arrestins; Benzimidazoles; beta-Arrestins; Biphenyl Compounds; CHO Cells; Cricetinae; Cricetulus; GTP-Binding Proteins; Humans; Phosphoproteins; Rats; Receptor, Angiotensin, Type 1; Tetrazoles; Up-Regulation; Valine; Valsartan; Zona Glomerulosa

2015
Impact of Aldosterone Synthase Inhibitor FAD286 on Steroid Hormone Profile in Human Adrenocortical Cells.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2017, Volume: 49, Issue:9

    Topics: Adrenal Cortex; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Cell Line; Cytochrome P-450 CYP11B2; Enzyme Inhibitors; Fadrozole; Gene Expression Regulation, Enzymologic; Glucocorticoids; Hormones; Humans; Receptor, Angiotensin, Type 1; RNA, Messenger; Steroids; Tetrazoles

2017