Page last updated: 2024-08-23

canadine and berberine

canadine has been researched along with berberine in 60 studies

Research

Studies (60)

Timeframe	Studies, this research(%)	All Research%
pre-1990	12 (20.00)	18.7374
1990's	17 (28.33)	18.2507
2000's	7 (11.67)	29.6817
2010's	20 (33.33)	24.3611
2020's	4 (6.67)	2.80

Authors

Authors	Studies
Huang, KX; Jin, GZ	1
Li, DX; Wang, W; Xuan, B	2
Fujimura, H; Mibu, H; Niwa, M; Nozaki, M; Tsurumi, K	1
Cao, XD; Jiang, JW; Wu, G; Wu, GC	1
Chen, Y; Han, YR; Jin, GZ; Xu, SX; Yu, LP	1
Jiang, Y; Liu, GQ; Peng, G; Zhou, LQ	1
Jin, GZ; Shi, WX; Wang, XL	1
Belcheva, A; Ivanov, C; Manevska, B; Zhelyazkov, D	1
Jin, GZ; Li, JH; Wang, XL; Yu, LP	1
Bentley, KW	1
Hong, GX; Jin, GZ; Wang, XL	1
Jin, GZ; Wang, XL; Zhou, TC	1
Li, DX; Zhou, J	1
Han, Q; Jiang, MH; Jin, GZ; Miao, YS; Yang, S	1
Li, DX; Sun, AY	1
Li, DX; Xuan, B; Zhou, J	1
Li, XT; Wang, JX; Wang, YL; Yang, SJ	1
Jin, GZ; Wu, J	3
Baker, W; Gentry, EJ; Humble, D; Jampani, HB; Keshavarz-Shokri, A; Mitscher, LA; Morton, MD; Shawar, R; Telikepalli, H; Velde, DV	1
Han, QD; Jin, GZ; Lu, ZZ; Wei, X	1
Abdel-Haq, H; Cometa, MF; Leone, MG; Palmery, M; Saso, L; Silvestrini, B	1
Bock, A; Wanner, G; Zenk, MH	1
Guo, W; Jin, GZ; Zhang, WF; Zhao, RR; Zhi, JM	1
Xu, CQ	1
NIJLAND, MM; UFFELIE, OF	1
KONDO, Y; TAKEMOTO, T	1
GHEORGHIU, A; IONESCU-MATIU, E	1
BAO, DY; HSU, B; KIN, KC; WANG, YE	1
FACQUET, J	1
Facchini, PJ; Park, SU; Samanani, N	1
Luo, XP; Shi, YP; Wu, XM; Zhai, ZD	1
Bilski, P; Chignell, CF; He, YY; Inbaraj, JJ; Kukielczak, BM; Sik, RH	1
Andujar, SA; Correché, ER; Enriz, RD; Freile, ML; Gómez Lechón, MJ; Kurdelas, RR	1
Jin, GZ; Liu, Q; Wakui, M; Wu, C; Wu, J; Yang, K; Zhen, X	1
Burns, JT; Cech, NB; Ettefagh, KA; Junio, HA; Kaatz, GW	1
Jin, M; Kim, KH; Lee, KR; Lee, SO; Lee, TH; Son, M	1
Imming, P; Meyer, A; Raunio, H; Salminen, KA	1
Chai, Y; Fan, G; Hong, Z; Le, J; Wen, J; Zhang, M	1
Chai, Y; Fan, G; Hong, Z; Shi, K; Wen, J; Zhang, Y	1
Lewis, DA; Siegel, BI; Verrico, CD; Volk, DW	1
Dang, TT; Facchini, PJ	1
Chen, X; Dang, TT; Facchini, PJ	1
Jeong, JS; Jung, JW; Kang, HE; Kwon, YS; Son, M	1
Cong, DL; Jiang, Y; Wang, Y; Yu, JJ; Zhao, CF; Zhou, Y	1
Kumarasamy, VM; Shin, YJ; Sun, D; White, J	1
Galanie, S; Smolke, CD	1
Bianucci, AM; Borghini, A; Pietra, D	1
Ouyang, Z; Sui, D; Wang, D; Wang, K; Wei, Y; Xu, H	1
Ayala, AP; Jain, S; Joshi, BD; Srivastava, A; Tandon, P	1
Amicucci, A; Antonini, E; Battistelli, S; Benedetti, S; Catalani, S; De Crescentini, L; Lombardi, P; Mantellini, F; Mari, G; Palma, F; Santeusanio, S	1
Farjon, J; Giraudeau, P; Le, PM; Martineau, E; Milande, C	1
Fan, JJ; Hu, G; Hu, YJ; Li, CH; Tan, CN; Yang, FQ; Zhang, Q	1
Cahlíková, L; Chlebek, J; Doležal, R; Hošťálková, A; Hrabinová, M; Jun, D; Korábečný, J; Kučera, T; Macáková, K; Opletal, L; Pérez, DI; Štěpánková, Š	1
Chen, DDY; Huang, ZA; Yahaya, N; Yan, B	1
Caesar, LK; Cech, NB; Kellogg, JJ; Khin, M	1
Anarbaev, RO; Bredikhin, RA; Chepanova, AA; Dyrkheeva, NS; Gladkova, ED; Ilina, ES; Lavrik, OI; Luzina, OA; Mamontova, EM; Nechepurenko, IV; Reynisson, J; Salakhutdinov, NF; Volcho, KP; Zakharenko, AL	1
Chen, F; Chen, W; Chen, Y; Jiang, M; Li, W; Tang, P; Yang, Z	1

Reviews

1 review(s) available for canadine and berberine

Article	Year
Beta-phenylethylamines and the isoquinoline alkaloids. Natural product reports, 1984, Volume: 1, Issue:4 Topics: Alkaloids; Animals; Benzophenanthridines; Berberine; Berberine Alkaloids; Colchicine; Emetine; Isoquinolines; Morphine Derivatives; Phenethylamines	1984

Other Studies

59 other study(ies) available for canadine and berberine

Article	Year
The antagonistic effects of tetrahydroprotoberberines on dopamine receptors: electrophysiological studies. Science in China. Series B, Chemistry, life sciences & earth sciences, 1992, Volume: 35, Issue:6 Topics: Alkaloids; Animals; Apomorphine; Berberine; Berberine Alkaloids; Dopamine Antagonists; Dose-Response Relationship, Drug; Electrophysiology; Neurons; Rats; Rats, Inbred Strains; Substantia Nigra	1992
[Protective effects of tetrahydroprotoberberines on experimental myocardial infarction in rats]. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1992, Volume: 13, Issue:2 Topics: Alkaloids; Animals; Aspartate Aminotransferases; Berberine; Berberine Alkaloids; Creatine Kinase; Female; Hemodynamics; Male; Myocardial Infarction; Rats; Rats, Inbred Strains	1992
Dopaminergic unique affinity of tetrahydroberberine and l-tetrahydroberberine-d-camphor sulfonate. Pharmacology, 1991, Volume: 43, Issue:6 Topics: Animals; Apomorphine; Berberine; Camphor; Chlorpromazine; Diazepam; Drug Combinations; Male; Mastication; Mice; Mice, Inbred Strains; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Sleep; Tritium	1991
[Potentiation of electroacupuncture analgesia by l-tetrahydropalmatine and its analogues in rabbits]. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1990, Volume: 11, Issue:2 Topics: Acupuncture Analgesia; Alkaloids; Animals; Berberine; Berberine Alkaloids; Electroacupuncture; Female; Male; Pain; Rabbits; Sensory Thresholds	1990
Effects of tetrahydroprotoberberines on dopamine receptor subtypes in brain. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1989, Volume: 10, Issue:2 Topics: Adenylyl Cyclases; Alkaloids; Animals; Berberine; Berberine Alkaloids; Brain; Cattle; Corpus Striatum; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Stereoisomerism	1989
[Effect of some isoquinoline alkaloids on monoamines in the rat brain]. Yao xue xue bao = Acta pharmaceutica Sinica, 1985, Volume: 20, Issue:8 Topics: Alkaloids; Animals; Antipsychotic Agents; Berberine; Berberine Alkaloids; Biogenic Amines; Brain; Corpus Striatum; Dopamine; Female; Isoquinolines; Limbic System; Male; Rats	1985
Tetrahydroprotoberberine--a new chemical type of antagonist of dopamine receptors. Scientia Sinica. Series B, Chemical, biological, agricultural, medical & earth sciences, 1986, Volume: 29, Issue:5 Topics: Alkaloids; Animals; Antipsychotic Agents; Berberine; Berberine Alkaloids; Corpus Striatum; Haloperidol; Rats; Receptors, Dopamine; Scopolamine; Substantia Nigra	1986
[The effect of the beta adrenomimetic trimethoquinol and its rigid tetrahydroberberine conformer on histamine liberation induced by compound 48/80 in mast cells]. Biomedica biochimica acta, 1984, Volume: 43, Issue:6 Topics: Adrenergic beta-Agonists; Animals; Berberine; Berberine Alkaloids; Histamine Release; Isoquinolines; Male; Mast Cells; Molecular Conformation; p-Methoxy-N-methylphenethylamine; Rats; Rats, Inbred Strains; Tretoquinol	1984
[Effect of tetrahydroberberine on blockade of pre- and postsynaptic dopamine receptors (author's transl)]. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1982, Volume: 3, Issue:2 Topics: 4-Butyrolactone; Animals; Apomorphine; Berberine; Berberine Alkaloids; Corpus Striatum; Hypnotics and Sedatives; Levodopa; Rats; Receptors, Dopamine	1982
[Relevance of dopaminergic system to the catalepsy induced by tetrahydroberberine (author's transl)]. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1981, Volume: 2, Issue:4 Topics: Animals; Apomorphine; Berberine; Berberine Alkaloids; Catalepsy; Female; Haloperidol; Humans; Male; Mice; Parasympathetic Nervous System; Rats; Receptors, Dopamine	1981
[On the central inhibition action of tetrahydroberberine without relevance to GABA receptors]. Sheng li xue bao : [Acta physiologica Sinica], 1994, Volume: 46, Issue:5 Topics: Animals; Anticonvulsants; Berberine; Female; Male; Mice; Mice, Inbred Strains; Muscle Contraction; Muscle, Skeletal; Oligochaeta; Receptors, GABA	1994
Inhibitory effect of tetrahydroberberine on platelet aggregation and thrombosis. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1994, Volume: 15, Issue:2 Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Berberine; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Rats; Rats, Sprague-Dawley; Thrombosis; Thromboxane B2	1994
Effects of tetrahydroberberine on isoproterenol-stimulated mitochondrial 45Ca uptake in rabbit myocardia. Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, 1993, Volume: 13, Issue:4 Topics: Animals; Berberine; Calcium; Calcium Radioisotopes; Isoproterenol; Male; Mitochondria, Heart; Rabbits	1993
Effects of (-)-stepholidine and tetrahydroberberine on high potassium-evoked contraction and calcium influx in rat artery. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1993, Volume: 14, Issue:3 Topics: Animals; Aorta, Thoracic; Berberine; Calcium Channel Blockers; Calcium-Transporting ATPases; Dopamine Antagonists; Female; Male; Muscle Contraction; Muscle, Smooth, Vascular; Rats; Rats, Wistar; Verapamil	1993
Antifibrillatory effect of tetrahydroberberine. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1993, Volume: 14, Issue:4 Topics: Aconitine; Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Barium Compounds; Berberine; Cesium; Chlorides; Female; Guinea Pigs; Male; Ouabain; Rabbits; Rats; Rats, Sprague-Dawley; Ventricular Fibrillation	1993
Effects of tetrahydroberberine on ischemic and reperfused myocardium in rats. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1993, Volume: 14, Issue:2 Topics: Animals; Anti-Arrhythmia Agents; Berberine; Berberine Alkaloids; In Vitro Techniques; Male; Malondialdehyde; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Rats; Rats, Sprague-Dawley; Verapamil; Xanthine Oxidase	1993
[Effects of tetrahydroprotoberberines on cytosolic free calcium in cultured rat single myocardial cells]. Yao xue xue bao = Acta pharmaceutica Sinica, 1995, Volume: 30, Issue:8 Topics: Animals; Animals, Newborn; Berberine; Berberine Alkaloids; Biological Transport, Active; Calcium; Calcium Channel Blockers; Cells, Cultured; Myocardium; Rats; Rats, Sprague-Dawley; Verapamil	1995
Tetrahydroberberine suppresses dopamine-induced potassium current in acutely dissociated CA1 pyramidal neurons from rat hippocampus. Neuroscience letters, 1996, Apr-05, Volume: 207, Issue:3 Topics: Animals; Berberine; Calcium Channel Blockers; Dopamine; Dose-Response Relationship, Drug; Hippocampus; Potassium Channels; Pyramidal Cells; Rats; Rats, Wistar	1996
Tetrahydroberberine inhibits acetylcholine-induced K+ current in acutely dissociated rat hippocampal CA1 pyramidal neurons. Neuroscience letters, 1997, Jan-31, Volume: 222, Issue:2 Topics: Acetylcholine; Animals; Berberine; Calcium Channel Blockers; Hippocampus; Patch-Clamp Techniques; Potassium; Pyramidal Cells; Rats	1997
Tetrahydroberberine blocks membrane K+ channels underlying its inhibition of intracellular message-mediated outward currents in acutely dissociated CA1 neurons from rat hippocampus. Brain research, 1997, Nov-14, Volume: 775, Issue:1-2 Topics: Animals; Berberine; Dopamine Antagonists; Electrophysiology; Hippocampus; In Vitro Techniques; Membrane Potentials; Neurons; Patch-Clamp Techniques; Potassium Channel Blockers; Rats; Rats, Wistar	1997
Antitubercular natural products: berberine from the roots of commercial Hydrastis canadensis powder. Isolation of inactive 8-oxotetrahydrothalifendine, canadine, beta-hydrastine, and two new quinic acid esters, hycandinic acid esters-1 and -2. Journal of natural products, 1998, Volume: 61, Issue:10 Topics: Alkaloids; Antitubercular Agents; Benzylisoquinolines; Berberine; Biological Products; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Plant Roots; Plants, Medicinal; Quinic Acid	1998
[Antagonistic effect of tetrahydroproberberine homologues on alpha 1-adrenoceptor]. Yao xue xue bao = Acta pharmaceutica Sinica, 1996, Volume: 31, Issue:9 Topics: Adrenergic alpha-Antagonists; Animals; Berberine; Berberine Alkaloids; Binding, Competitive; Male; Rats; Receptors, Adrenergic, alpha-1; Vasoconstriction	1996
Relaxant effects of Hydrastis canadensis L. and its major alkaloids on guinea pig isolated trachea. Pharmacology & toxicology, 2000, Volume: 87, Issue:5 Topics: Alkaloids; Animals; Benzylisoquinolines; Berberine; Bronchodilator Agents; Complementary Therapies; Drug Synergism; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Plant Extracts; Plants, Medicinal; Trachea	2000
Immunocytological localization of two enzymes involved in berberine biosynthesis. Planta, 2002, Volume: 216, Issue:1 Topics: Alkaloids; Benzylisoquinolines; Berberine; Berberine Alkaloids; Berberis; Cells, Cultured; Eschscholzia; Immunohistochemistry; Isoquinolines; Microscopy, Immunoelectron; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Oxidoreductases, N-Demethylating; Papaver; Plant Cells; Plants; Vacuoles	2002
[Effects of tetrahydroberberine on peripheral vascular dopamine DA1 and DA2 receptor subtypes]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2000, Volume: 25, Issue:8 Topics: Animals; Berberine; Dopamine D2 Receptor Antagonists; Female; In Vitro Techniques; Male; Rabbits; Receptors, Dopamine D1; Receptors, Dopamine D2; Vasodilation	2000
[Research on the mechanism of neuronal apoptosis in Alzheimer's disease and the effects of tetrohydroberberine on the apoptosis]. Sheng li ke xue jin zhan [Progress in physiology], 1999, Volume: 30, Issue:3 Topics: Alzheimer Disease; Amyloid beta-Peptides; Apoptosis; Berberine; Cells, Cultured; Hippocampus; Humans; Neurons	1999
[Paper chromatographic separation of d- and 1-canadine]. Pharmaceutisch weekblad, 1958, Nov-29, Volume: 93, Issue:24 Topics: Berberine; Biological Products; Chromatography, Paper; Hydrastis; Rare Diseases	1958
[Reactions of protoberberine-type alkaloids. IV. Synthesis of tetrahydroberberine N-Oxide]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1963, Volume: 83 Topics: Alkaloids; Berberine; Berberine Alkaloids; Organic Chemicals; Oxides	1963
[CONTRIBUTION TO THE STUDY OF ALKALOIDS FROM CORYDALIS SOLIDA (L.) SW. EXTRACTION, ISOLATION AND PURIFICATION OF D-CANADINE]. Annales pharmaceutiques francaises, 1964, Volume: 22 Topics: Alkaloids; Berberine; Chemistry, Pharmaceutical; Corydalis; Pharmacy; Research	1964
[THE PHYSIOLOGIC DISPOSITION OF TETRAHYDROBERBERINE]. Sheng li xue bao : [Acta physiologica Sinica], 1965, Volume: 28 Topics: Alkaloids; Animals; Berberine; Lagomorpha; Metabolism; Mice; Rabbits; Rats; Research	1965
[The action of tetrahydroberberine HC1 on arterial hypertension]. Gazette medicale de France, 1954, Volume: 61, Issue:24 Topics: Alkaloids; Berberine; Hypertension	1954
Cell type-specific localization of transcripts encoding nine consecutive enzymes involved in protoberberine alkaloid biosynthesis. The Plant cell, 2005, Volume: 17, Issue:3 Topics: Berberine; Berberine Alkaloids; Cloning, Molecular; DNA, Complementary; DNA, Plant; Genes, Plant; Molecular Sequence Data; Papaver; Plant Proteins; Plant Roots; Rhizome; RNA, Plant; Species Specificity; Thalictrum; Tissue Distribution; Transcription, Genetic	2005
Chiral high-performance liquid chromatographic separation of the enantiomers of tetrahydropalmatine and tetrahydroberberine, isolated from Corydalis yanhusuo. Analytical and bioanalytical chemistry, 2006, Volume: 384, Issue:4 Topics: Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Corydalis; Spectrum Analysis; Stereoisomerism	2006
Photochemistry and photocytotoxicity of alkaloids from Goldenseal (Hydrastis canadensis L.). 2. Palmatine, hydrastine, canadine, and hydrastinine. Chemical research in toxicology, 2006, Volume: 19, Issue:6 Topics: Alkaloids; Benzylisoquinolines; Berberine; Berberine Alkaloids; Cell Line; Cell Survival; Humans; Hydrastis; Molecular Structure; Oxygen; Photochemistry; Photosensitizing Agents; Spectrum Analysis; Tetrahydroisoquinolines	2006
Antioxidant and cytotoxic activities of canadine: biological effects and structural aspects. Bioorganic & medicinal chemistry, 2008, Apr-01, Volume: 16, Issue:7 Topics: Animals; Antioxidants; Berberine; Cell Survival; Cells, Cultured; Glutathione; Hepatocytes; Male; Models, Molecular; Molecular Structure; Rats; Rats, Sprague-Dawley	2008
Tetrahydroberberine blocks ATP-sensitive potassium channels in dopamine neurons acutely-dissociated from rat substantia nigra pars compacta. Neuropharmacology, 2010, Volume: 59, Issue:7-8 Topics: Animals; Berberine; Dopamine; In Vitro Techniques; KATP Channels; Neurons; Neuroprotective Agents; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Dopamine D2; Substantia Nigra	2010
Goldenseal (Hydrastis canadensis L.) extracts synergistically enhance the antibacterial activity of berberine via efflux pump inhibition. Planta medica, 2011, Volume: 77, Issue:8 Topics: Alkaloids; Anti-Bacterial Agents; Bacterial Proteins; Benzylisoquinolines; Berberine; Drug Synergism; Ethidium; Hydrastis; Multidrug Resistance-Associated Proteins; Plant Components, Aerial; Plant Extracts; Plant Roots; Staphylococcus aureus	2011
Tetrahydroberberine, an isoquinoline alkaloid isolated from corydalis tuber, enhances gastrointestinal motor function. The Journal of pharmacology and experimental therapeutics, 2011, Volume: 338, Issue:3 Topics: Animals; Berberine; Binding, Competitive; CHO Cells; Corydalis; Cricetinae; Cricetulus; Dogs; Dyspepsia; Electromyography; Gastric Fundus; Gastrointestinal Motility; HEK293 Cells; Humans; Male; Muscle Relaxation; Plant Extracts; Plant Roots; Radioligand Assay; Rats; Rats, Sprague-Dawley; Stimulation, Chemical	2011
CYP2C19 progress curve analysis and mechanism-based inactivation by three methylenedioxyphenyl compounds. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:12 Topics: Aporphines; Aryl Hydrocarbon Hydroxylases; Benzophenanthridines; Berberine; Berberine Alkaloids; Cytochrome P-450 CYP2C19; Enzyme Inhibitors; Humans	2011
Simultaneous determination of tetrahydropalmatine and tetrahydroberberine in rat urine using dispersive liquid-liquid microextraction coupled with high-performance liquid chromatography. Journal of separation science, 2011, Volume: 34, Issue:22 Topics: Animals; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Liquid Phase Microextraction; Rats	2011
Chiral HPLC determination and stereoselective pharmacokinetics of tetrahydroberberine enantiomers in rats. Chirality, 2012, Volume: 24, Issue:3 Topics: Animals; Berberine; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Stereoisomerism; Substrate Specificity	2012
Endocannabinoid metabolism in the prefrontal cortex in schizophrenia. Schizophrenia research, 2013, Volume: 147, Issue:1 Topics: Adolescent; Adult; Age Factors; Animals; Antipsychotic Agents; Benzodiazepines; Berberine; Calcium Channel Blockers; Endocannabinoids; Female; Gene Expression Regulation; Haloperidol; Humans; Macaca fascicularis; Male; Middle Aged; Monoacylglycerol Lipases; Olanzapine; Prefrontal Cortex; Schizophrenia; Young Adult	2013
Cloning and characterization of canadine synthase involved in noscapine biosynthesis in opium poppy. FEBS letters, 2014, Jan-03, Volume: 588, Issue:1 Topics: Amino Acid Sequence; Berberine; Berberine Alkaloids; Biosynthetic Pathways; Chromatography, Liquid; Cloning, Molecular; Cytochrome P-450 Enzyme System; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Gene Silencing; Immunoblotting; Mass Spectrometry; Molecular Sequence Data; Molecular Structure; Noscapine; Papaver; Phylogeny; Plant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Substrate Specificity	2014
Acetylation serves as a protective group in noscapine biosynthesis in opium poppy. Nature chemical biology, 2015, Volume: 11, Issue:2 Topics: Acetylation; Berberine; Biosynthetic Pathways; Cyclization; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Gene Silencing; Hydroxylation; Noscapine; Papaver; Plant Proteins; Recombinant Proteins; Substrate Specificity	2015
Pharmacokinetics and brain distribution of tetrahydropalmatine and tetrahydroberberine after oral administration of DA-9701, a new botanical gastroprokinetic agent, in rats. Biological & pharmaceutical bulletin, 2015, Volume: 38, Issue:2 Topics: Administration, Oral; Animals; Berberine; Berberine Alkaloids; Brain; Gastrointestinal Agents; Male; Plant Preparations; Rats, Sprague-Dawley; Tissue Distribution	2015
[Study on alkaloids of Corydalis ochotensis and their antitumor bioactivity]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2014, Volume: 37, Issue:10 Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Benzophenanthridines; Berberine; Berberine Alkaloids; Cell Line, Tumor; Corydalis; Humans; Isoquinolines	2014
Selective repression of RET proto-oncogene in medullary thyroid carcinoma by a natural alkaloid berberine. BMC cancer, 2015, Aug-26, Volume: 15 Topics: Antineoplastic Agents; Berberine; Biological Products; Carcinoma, Neuroendocrine; Cell Line, Tumor; Gene Expression; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Promoter Regions, Genetic; Proto-Oncogene Mas; Proto-Oncogene Proteins c-ret; Thyroid Neoplasms; Transcriptional Activation	2015
Optimization of yeast-based production of medicinal protoberberine alkaloids. Microbial cell factories, 2015, Sep-16, Volume: 14 Topics: Batch Cell Culture Techniques; Berberine; Berberine Alkaloids; Bioreactors; Biosynthetic Pathways; Cytochrome P-450 Enzyme System; Fermentation; Gene Dosage; Metabolic Engineering; Pilot Projects; Saccharomyces cerevisiae; Tetrahydropapaveroline	2015
In vitro studies of antifibrotic and cytoprotective effects elicited by proto-berberine alkaloids in human dermal fibroblasts. Pharmacological reports : PR, 2015, Volume: 67, Issue:6 Topics: Berberine; Berberine Alkaloids; Cell Proliferation; Cells, Cultured; Collagen; Cytoprotection; Fibroblasts; Fibrosis; Free Radicals; Humans; Hydrogen Peroxide; Interleukin-1beta; Interleukin-6; Mitochondria; Oxidoreductases; Protective Agents; Transforming Growth Factor beta1	2015
Effects of tetrahydroberberine and tetrahydropalmatine on hepatic cytochrome P450 expression and their toxicity in mice. Chemico-biological interactions, 2017, Apr-25, Volume: 268 Topics: Animals; Aspartate Aminotransferases; Berberine; Berberine Alkaloids; Bilirubin; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Glutathione; Liver; Male; Malondialdehyde; Mice, Inbred C57BL; RNA, Messenger	2017
A combined experimental (IR, Raman and UV-Vis) and quantum chemical study of canadine. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2018, Feb-15, Volume: 191 Topics: Berberine; Models, Molecular; Molecular Conformation; Nonlinear Dynamics; Quantum Theory; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Static Electricity; Thermodynamics; Vibration	2018
Synthesis and biological evaluation of novel heteroring-annulated pyrrolino-tetrahydroberberine analogues as antioxidant agents. Bioorganic & medicinal chemistry, 2018, 10-01, Volume: 26, Issue:18 Topics: Antioxidants; Berberine; Cell Line; Cell Proliferation; Cell Survival; DNA; DNA Breaks; Dose-Response Relationship, Drug; Ferrous Compounds; Free Radicals; Humans; Hydrogen Peroxide; Keratinocytes; Molecular Structure; Pyrroles; Structure-Activity Relationship	2018
Quantification of natural products in herbal supplements: A combined NMR approach applied on goldenseal. Journal of pharmaceutical and biomedical analysis, 2019, Feb-20, Volume: 165 Topics: Alkaloids; Benzylisoquinolines; Berberine; Biological Products; Chromatography, High Pressure Liquid; Hydrastis; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Mass Spectrometry; Plant Extracts; Plant Roots; Reproducibility of Results	2019
Potential target-related proteins in rabbit platelets treated with active monomers dehydrocorydaline and canadine from Rhizoma corydalis. Phytomedicine : international journal of phytotherapy and phytopharmacology, 2019, Feb-15, Volume: 54 Topics: Adenosine Diphosphate; Alkaloids; Animals; Berberine; Blood Platelets; Blood Proteins; Corydalis; Enzyme-Linked Immunosorbent Assay; Platelet Aggregation; Platelet Aggregation Inhibitors; Proteomics; Rabbits; Tandem Mass Spectrometry	2019
In Vitro and In Silico Acetylcholinesterase Inhibitory Activity of Thalictricavine and Canadine and Their Predicted Penetration across the Blood-Brain Barrier. Molecules (Basel, Switzerland), 2019, Apr-05, Volume: 24, Issue:7 Topics: Acetylcholinesterase; Alkaloids; Alzheimer Disease; Berberine; Biological Transport; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Computer Simulation; Corydalis; Disaccharides; Humans; Models, Molecular; Nitro Compounds; Protein Binding	2019
Enantioselective analysis in complex matrices using capillary electrophoresis-mass spectrometry: A case study of the botanical drug Corydalis Rhizoma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2020, Sep-01, Volume: 1152 Topics: Berberine; Berberine Alkaloids; Corydalis; Electrophoresis, Capillary; Limit of Detection; Linear Models; Mass Spectrometry; Models, Chemical; Plant Extracts; Reproducibility of Results; Stereoisomerism	2020
Chemical Evaluation of the Effects of Storage Conditions on the Botanical Goldenseal using Marker-based and Metabolomics Approaches. The Yale journal of biology and medicine, 2020, Volume: 93, Issue:2 Topics: Benzylisoquinolines; Berberine; Berberine Alkaloids; Drug Stability; Drug Storage; Humans; Hydrastis; Infections; Mass Spectrometry; Plant Preparations; Plant Roots; Principal Component Analysis	2020
The First Berberine-Based Inhibitors of Tyrosyl-DNA Phosphodiesterase 1 (Tdp1), an Important DNA Repair Enzyme. International journal of molecular sciences, 2020, Sep-28, Volume: 21, Issue:19 Topics: Antineoplastic Agents, Phytogenic; Berberine; Binding Sites; DNA Repair; Drug Combinations; Drug Design; Drug Synergism; HeLa Cells; Humans; Inhibitory Concentration 50; Molecular Docking Simulation; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Protein Binding; Protein Conformation; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topotecan	2020
Total Synthesis of (-)-Canadine, (-)-Rotundine, (-)-Sinactine, and (-)-Xylopinine Using a Last-Step Enantioselective Ir-Catalyzed Hydrogenation. The Journal of organic chemistry, 2021, 06-18, Volume: 86, Issue:12 Topics: Berberine; Berberine Alkaloids; Catalysis; Hydrogenation; Stereoisomerism	2021