Page last updated: 2024-08-22

camptothecin and warfarin

camptothecin has been researched along with warfarin in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19902 (8.00)18.7374
1990's4 (16.00)18.2507
2000's6 (24.00)29.6817
2010's13 (52.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Baloch, Z; Coffman, FD; Cohen, S1
Gottesfeld, JM1
Chignell, CF1
Pommier, Y; Shimizu, T1
Kulpa, V; Tua, A; Wang, J; Wernette, CM1
Cao, CX; Pommier, Y; Shao, RG; Shimizu, T1
Harada, N; Ishikawa, T; Keramaris, E; MacLaurin, J; Nicholson, DW; Park, DS; Robertson, GS; Slack, RS; Stefanis, L; Takaku, K; Taketo, MM1
Doi, S; Ikegami, Y; Kitazaki, T; Kohno, S; Mizuta, Y; Murase, K; Nakamura, Y; Nakatomi, K; Oka, M; Ross, DD; Shiozawa, K; Soda, H; Tsurutani, J; Yoshida, H; Yoshikawa, M1
Bailly, C; Gago, F; Ishibashi, F; Iwao, M; Laine, W; Lansiaux, A; Marco, E; Tardy, C1
Bailly, C; Beauvillain, JC; Cuevas, C; Gallego, MA; Kluza, J; Loyens, A; Marchetti, P; Sousa-Faro, JM1
Cyrankiewicz, M; Kruszewski, S; Wybranowski, T; Ziomkowska, B1
Hanioka, N; Jinno, H; Koeda, A; Nagaoka, K; Naito, S; Narimatsu, S; Tanabe, N; Tanaka-Kagawa, T1
Kotsuji, F; Kurokawa, T; Masada, M; Matsunaga, A; Nakamura, T; Sawamura, Y; Shinagawa, A; Tsuyoshi, H; Yano, R; Yoneda, M; Yoshida, Y1
Bito, T; Fabian, G; Farago, N; Feher, LZ; Katona, RL; Kitajka, K; Kulin, S; Nagy, LI; Puskas, LG; Tiszlavicz, L; Tubak, V1
Begg, EJ; Helsby, NA; Jensen, BP1
Arakawa, R; Iwaki, Y; Kawasaki, H1
Guo, M; Hou, J; Lu, Y; Rong, WT; Wang, DF; Wang, Y; Xu, Q; Yu, SQ1
Pang, LQ; Qin, ZS; Wu, K; Xia, TF; Zhang, XS; Zhao, ZQ1
Jaggi, M; Joshi, V; Negi, LM; Ronodip, K; Talegaonkar, S1
Guo, D; Han, X; Ling, Y; Luo, J; Shi, C; Wang, L; Xu, G1
Agama, K; Lorence, N; Neuman, KC; Pommier, Y; Seol, Y; Zhang, H1
Collin, S; Criscuolo, A; Dahmane, N; Delmas, S; Desnoues, N; Eberhard, S; Forterre, P; Gadelle, D; Pommier, Y; Sezonov, G; Zhang, H1
Finel, M; Ge, GB; Järvinen, E; Troberg, J; Yang, L1

Reviews

2 review(s) available for camptothecin and warfarin

ArticleYear
Drug-protein binding: recent advances in methodology: spectroscopic techniques.
    Annals of the New York Academy of Sciences, 1973, Nov-26, Volume: 226

    Topics: Camptothecin; Dansyl Compounds; Dicumarol; Drug Interactions; Energy Transfer; Flufenamic Acid; Fluorescence; Humans; Methods; Molecular Conformation; Naphthalenesulfonates; Pharmaceutical Preparations; Protein Binding; Pyrazoles; Serum Albumin; Serum Albumin, Bovine; Spectrometry, Fluorescence; Spectrophotometry; Spectrophotometry, Ultraviolet; Tetracycline; Tryptophan; Warfarin

1973
Pharmacogenetics of drug-metabolizing enzymes: the prodrug hypothesis.
    Pharmacogenomics, 2012, Volume: 13, Issue:1

    Topics: Aryl Hydrocarbon Hydroxylases; Azathioprine; Camptothecin; Clopidogrel; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Enzymes; Glucuronosyltransferase; Humans; Inactivation, Metabolic; Irinotecan; Methyltransferases; Mixed Function Oxygenases; Prodrugs; Tamoxifen; Ticlopidine; Vitamin K Epoxide Reductases; Warfarin

2012

Other Studies

23 other study(ies) available for camptothecin and warfarin

ArticleYear
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Synergistic interactions between tumor necrosis factor and inhibitors of DNA topoisomerase I and II.
    Journal of immunology (Baltimore, Md. : 1950), 1990, Nov-01, Volume: 145, Issue:9

    Topics: Aminocoumarins; Camptothecin; Cell Line; Cell Survival; Coumarins; Drug Synergism; In Vitro Techniques; L Cells; Novobiocin; Teniposide; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Necrosis Factor-alpha

1990
Novobiocin inhibits RNA polymerase III transcription in vitro by a mechanism distinct from DNA topoisomerase II.
    Nucleic acids research, 1986, Mar-11, Volume: 14, Issue:5

    Topics: Aminocoumarins; Camptothecin; Coumarins; DNA-Directed RNA Polymerases; HeLa Cells; Novobiocin; RNA Polymerase III; RNA, Ribosomal; RNA, Transfer; Teniposide; Topoisomerase II Inhibitors; Transcription, Genetic

1986
Camptothecin-induced apoptosis in p53-null human leukemia HL60 cells and their isolated nuclei: effects of the protease inhibitors Z-VAD-fmk and dichloroisocoumarin suggest an involvement of both caspases and serine proteases.
    Leukemia, 1997, Volume: 11, Issue:8

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Camptothecin; Caspase 3; Caspases; Cell Nucleus; Cell-Free System; Coumarins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA Fragmentation; Gene Deletion; Genes, p53; HL-60 Cells; Humans; Isocoumarins; Lamin Type B; Lamins; Nuclear Proteins; Poly Adenosine Diphosphate Ribose; Prodrugs; Serine Endopeptidases; Serine Proteinase Inhibitors; Tumor Suppressor Protein p53

1997
Mitochondrial DNA topoisomerase I of Saccharomyces cerevisiae.
    Biochimie, 1997, Volume: 79, Issue:6

    Topics: Aminocoumarins; Camptothecin; Coumarins; Diminazene; Disinfectants; DNA Topoisomerases, Type I; Imidazoles; Mitochondria; Saccharomyces cerevisiae; Topoisomerase I Inhibitors

1997
Lamin B phosphorylation by protein kinase calpha and proteolysis during apoptosis in human leukemia HL60 cells.
    The Journal of biological chemistry, 1998, Apr-10, Volume: 273, Issue:15

    Topics: Amino Acid Sequence; Apoptosis; Camptothecin; Cell Nucleus; Coumarins; Cytosol; DNA Fragmentation; HL-60 Cells; Humans; Isocoumarins; Isoenzymes; Kinetics; Lamin Type B; Lamins; Molecular Sequence Data; Nuclear Proteins; Peptide Fragments; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Protein Structure, Secondary; Serine Proteinase Inhibitors; Time Factors; Topoisomerase I Inhibitors; Tumor Suppressor Protein p53

1998
Involvement of caspase 3 in apoptotic death of cortical neurons evoked by DNA damage.
    Molecular and cellular neurosciences, 2000, Volume: 15, Issue:4

    Topics: Animals; Apoptosis; Brain; Camptothecin; Caspase 3; Caspases; Coumarins; Cytochrome c Group; DNA Damage; DNA Fragmentation; Enzyme Inhibitors; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; In Situ Nick-End Labeling; Mice; Mice, Knockout; Neurons; Oligopeptides

2000
Reversal of breast cancer resistance protein (BCRP/ABCG2)-mediated drug resistance by novobiocin, a coumermycin antibiotic.
    International journal of cancer, 2004, Jan-01, Volume: 108, Issue:1

    Topics: Aminocoumarins; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Camptothecin; Coumarins; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Irinotecan; Lung Neoplasms; Mitoxantrone; Neoplasm Proteins; Novobiocin; Topoisomerase I Inhibitors; Topotecan; Tumor Cells, Cultured

2004
Molecular determinants of topoisomerase I poisoning by lamellarins: comparison with camptothecin and structure-activity relationships.
    Journal of medicinal chemistry, 2005, Jun-02, Volume: 48, Issue:11

    Topics: Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Computer Simulation; Coumarins; DNA Topoisomerases, Type I; Drug Resistance, Neoplasm; Heterocyclic Compounds, 4 or More Rings; Humans; Intercalating Agents; Isoquinolines; Models, Molecular; Protein Binding; Structure-Activity Relationship; Thermodynamics; Topoisomerase I Inhibitors

2005
Cancer cell mitochondria are direct proapoptotic targets for the marine antitumor drug lamellarin D.
    Cancer research, 2006, Mar-15, Volume: 66, Issue:6

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Camptothecin; Cell Line, Tumor; Cell Membrane Permeability; Cell-Free System; Coumarins; Cytochromes c; Heterocyclic Compounds, 4 or More Rings; Humans; Isoquinolines; Leukemia P388; Lung Neoplasms; Membrane Potentials; Mice; Mitochondria; Mitochondrial Membranes; NIH 3T3 Cells; Rats

2006
The HSA affinity of warfarin and flurbiprofen determined by fluorescence anisotropy measurements of camptothecin.
    Bio Systems, 2008, Volume: 94, Issue:3

    Topics: Binding, Competitive; Camptothecin; Fluorescence Polarization; Flurbiprofen; Humans; Protein Binding; Serum Albumin; Warfarin

2008
Functional characterization of human and cynomolgus monkey UDP-glucuronosyltransferase 1A1 enzymes.
    Life sciences, 2010, Aug-14, Volume: 87, Issue:7-8

    Topics: Amino Acid Sequence; Animals; Camptothecin; Coumarins; Estradiol; Gene Expression; Glucuronosyltransferase; Humans; Irinotecan; Macaca fascicularis; Molecular Sequence Data; Recombinant Proteins; Sequence Alignment

2010
Transient elevation of international normalized ratio during cisplatin-based chemotherapy in patients who are taking warfarin.
    The Annals of pharmacotherapy, 2011, Volume: 45, Issue:10

    Topics: Anticoagulants; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Drug Interactions; Drug Monitoring; Female; Genital Neoplasms, Female; Humans; International Normalized Ratio; Irinotecan; Middle Aged; Thromboembolism; Treatment Outcome; Venous Thrombosis; Warfarin

2011
High-density real-time PCR-based in vivo toxicogenomic screen to predict organ-specific toxicity.
    International journal of molecular sciences, 2011, Volume: 12, Issue:9

    Topics: Aniline Compounds; Animals; Antineoplastic Agents; Brain; Camptothecin; Coumarins; Doxorubicin; Female; Heart; Irinotecan; Kidney; Mice, Inbred BALB C; Myocardium; Phenylenediamines; Real-Time Polymerase Chain Reaction; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; Rotenone; Sulfasalazine; Toxicogenetics; Transcriptome; Xenobiotics

2011
Human serum albumin-modified Fe3O4 magnetic nanoparticles for affinity-SALDI-MS of small-molecule drugs in biological liquids.
    Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2012, Volume: 28, Issue:9

    Topics: Camptothecin; Ferrosoferric Oxide; Humans; Ibuprofen; Magnetite Nanoparticles; Molecular Weight; Phenytoin; Sensitivity and Specificity; Serum Albumin; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Warfarin

2012
Mechanisms of chitosan-coated poly(lactic-co-glycolic acid) nanoparticles for improving oral absorption of 7-ethyl-10-hydroxycamptothecin.
    Nanotechnology, 2013, Jun-21, Volume: 24, Issue:24

    Topics: Absorption; Animals; Caco-2 Cells; Calorimetry, Differential Scanning; Camptothecin; Cell Death; Chitosan; Coated Materials, Biocompatible; Coumarins; Enterocytes; HT29 Cells; Humans; Intestines; Irinotecan; Kinetics; Lactic Acid; Male; Nanoparticles; Particle Size; Perfusion; Permeability; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Rhodamine 123; Spectroscopy, Fourier Transform Infrared; Static Electricity; X-Ray Diffraction

2013
Herb-drug interaction between irinotecan and psoralidin-containing herbs.
    European journal of drug metabolism and pharmacokinetics, 2015, Volume: 40, Issue:4

    Topics: Animals; Benzofurans; Camptothecin; Colon; Coumarins; Dose-Response Relationship, Drug; Herb-Drug Interactions; Humans; Irinotecan; Male; Mice; Mice, 129 Strain

2015
Hyaluronic acid decorated lipid nanocarrier for MDR modulation and CD-44 targeting in colon adenocarcinoma.
    International journal of biological macromolecules, 2015, Volume: 72

    Topics: Adenocarcinoma; Camptothecin; Colonic Neoplasms; Coumarins; Drug Delivery Systems; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Hyaluronan Receptors; Hyaluronic Acid; Irinotecan; Lipids; Nanoparticles; Thiazoles

2015
Functional-segregated coumarin-containing telodendrimer nanocarriers for efficient delivery of SN-38 for colon cancer treatment.
    Acta biomaterialia, 2015, Volume: 21

    Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Colonic Neoplasms; Coumarins; Dendrimers; Drug Carriers; Humans; Irinotecan; Molecular Dynamics Simulation; Nanostructures

2015
Single-Molecule Supercoil Relaxation Assay as a Screening Tool to Determine the Mechanism and Efficacy of Human Topoisomerase IB Inhibitors.
    Molecular cancer therapeutics, 2015, Volume: 14, Issue:11

    Topics: Antineoplastic Agents; Benzodioxoles; Camptothecin; Cell Line, Tumor; Cell Proliferation; Coumarins; DNA Cleavage; DNA Topoisomerases, Type I; DNA, Superhelical; Heterocyclic Compounds, 4 or More Rings; Humans; Inhibitory Concentration 50; Isoquinolines; Kinetics; Molecular Structure; Nucleic Acid Conformation; Substrate Specificity; Topoisomerase I Inhibitors

2015
topIb, a phylogenetic hallmark gene of Thaumarchaeota encodes a functional eukaryote-like topoisomerase IB.
    Nucleic acids research, 2016, Apr-07, Volume: 44, Issue:6

    Topics: Amino Acid Sequence; Archaea; Archaeal Proteins; Camptothecin; Cloning, Molecular; Coumarins; DNA Topoisomerases, Type I; DNA, Superhelical; Escherichia coli; Gene Expression; Heterocyclic Compounds, 4 or More Rings; Hot Temperature; Humans; Isoquinolines; Mitochondrial Proteins; Models, Molecular; Molecular Sequence Data; Phylogeny; Protein Stability; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Sequence Alignment; Topoisomerase I Inhibitors

2016
UGT1A10 Is a High Activity and Important Extrahepatic Enzyme: Why Has Its Role in Intestinal Glucuronidation Been Frequently Underestimated?
    Molecular pharmaceutics, 2017, 09-05, Volume: 14, Issue:9

    Topics: Animals; Blotting, Western; Camptothecin; Chromatography, High Pressure Liquid; Coumarins; Diclofenac; Estradiol; Estrone; Flavonoids; Glucuronosyltransferase; Humans; Hymecromone; Intestinal Mucosa; Irinotecan; Kinetics; Microsomes, Liver

2017