camptothecin has been researched along with valproic acid in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 4 (40.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Gupta, E; Ramirez, J; Ratain, MJ; Wang, X | 1 |
| de Jong, FA; Kitzen, JJ; Loos, WJ; Mathijssen, RH; Mathôt, RA; van den Bent, MJ; van der Bol, JM; Verweij, J | 1 |
| Hormozi, L; Parker, L; Song, J; Tanouye, MA | 1 |
| Bastien, S; Bicaku, E; Daud, AI; Dawson, J; DeConti, RC; Hausheer, FA; Lush, R; Marchion, D; Munster, PN; Neuger, A; Sullivan, DM | 1 |
| Aiba, K; Arakawa, Y; Saito, S; Yamada, H | 1 |
| Coy, DH; Fuselier, JA; Mackey, LV; Qian, Q; Sun, G; Sun, L; Yu, CY | 1 |
| Guo, GL; Schumacher, JD | 1 |
| Fan, L; Jiang, T; Qiu, X; Yin, Y; Zhu, Q | 1 |
| Chen, Y; Dai, Y; Ye, T; Zhang, Y | 1 |
1 review(s) available for camptothecin and valproic acid
| Article | Year |
|---|---|
Mechanistic review of drug-induced steatohepatitis.
Topics: Amiodarone; Animals; Camptothecin; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Fatty Liver; Hepatocytes; Humans; Irinotecan; Lipid Metabolism; Liver; Methotrexate; Mitochondria, Liver; Organoplatinum Compounds; Oxaliplatin; Perhexiline; Tamoxifen; Tetracycline; Valproic Acid | 2015 |
1 trial(s) available for camptothecin and valproic acid
| Article | Year |
|---|---|
Potentiation of a topoisomerase I inhibitor, karenitecin, by the histone deacetylase inhibitor valproic acid in melanoma: translational and phase I/II clinical trial.
Topics: Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell Line, Tumor; Drug Synergism; Enzyme Inhibitors; Female; Histone Deacetylase Inhibitors; Histones; Humans; Male; Melanoma; Mice; Mice, Nude; Middle Aged; Skin Neoplasms; Topoisomerase I Inhibitors; Valproic Acid | 2009 |
8 other study(ies) available for camptothecin and valproic acid
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Modulation of glucuronidation of SN-38, the active metabolite of irinotecan, by valproic acid and phenobarbital.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biotransformation; Camptothecin; Female; Glucuronates; Glucuronosyltransferase; Irinotecan; Metabolic Clearance Rate; Phenobarbital; Rats; Rats, Wistar; Valproic Acid | 1997 |
Irinotecan chemotherapy during valproic acid treatment: pharmacokinetic interaction and hepatotoxicity.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chromatography, High Pressure Liquid; Female; Glucuronates; Glucuronosyltransferase; Humans; Irinotecan; Liver; Middle Aged; Models, Biological; Transaminases; Treatment Outcome; Valproic Acid | 2007 |
DNA topoisomerase I inhibitors ameliorate seizure-like behaviors and paralysis in a Drosophila model of epilepsy.
Topics: Analysis of Variance; Animals; Animals, Genetically Modified; Bromates; Camptothecin; Disease Models, Animal; DNA Topoisomerases, Type I; Drosophila; Drosophila Proteins; Drug Administration Schedule; Electric Stimulation; Electroshock; Enzyme Inhibitors; Epilepsy; Evoked Potentials; Motor Neurons; Muscle, Skeletal; Mutation; Paralysis; Seizures; Topoisomerase I Inhibitors; Valproic Acid | 2008 |
Simultaneous treatment with camptothecin and valproic acid suppresses induction of Bcl-X(L) and promotes apoptosis of MCF-7 breast cancer cells.
Topics: Apoptosis; bcl-X Protein; Breast Neoplasms; Camptothecin; Caspase 3; Cell Cycle; Cell Line, Tumor; Drug Synergism; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Immunoblotting; Membrane Potential, Mitochondrial; RNA, Small Interfering; Valproic Acid | 2009 |
Valproic acid induces NET cell growth arrest and enhances tumor suppression of the receptor-targeted peptide-drug conjugate via activating somatostatin receptor type II.
Topics: Animals; Apoptosis; Camptothecin; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Mice; Mice, Nude; Neuroendocrine Tumors; Pancreatic Neoplasms; Peptides; Receptors, Notch; Receptors, Peptide; Receptors, Somatostatin; Repressor Proteins; Signal Transduction; Valproic Acid | 2016 |
Targeting histones for degradation in cancer cells as a novel strategy in cancer treatment.
Topics: Acetylation; Animals; Antineoplastic Agents; Apoptosis; Camptothecin; Cell Cycle; Cell Line, Tumor; DNA Damage; Drug Therapy, Combination; Etoposide; Gamma Rays; Histone Deacetylase Inhibitors; Histones; Homeostasis; Humans; Hydroxamic Acids; Methyl Methanesulfonate; Mice; Valproic Acid; Vorinostat | 2019 |
Synthesis and Antitumor Evaluation of Biotin-SN38-Valproic Acid Conjugates.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biotin; Camptothecin; Cell Line, Tumor; Fibroblasts; HeLa Cells; Humans; Irinotecan; Mice; NIH 3T3 Cells; Valproic Acid | 2023 |