camptothecin has been researched along with tosylphenylalanyl chloromethyl ketone in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (46.15) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Guendisch, D; Kondratyuk, TP; Marler, L; Park, EJ; Pezzuto, JM; Shen, L; Sun, D; Wright, AD | 1 |
| Jadhav, A; Kerns, E; Nguyen, K; Shah, P; Sun, H; Xu, X; Yan, Z; Yu, KR | 1 |
| Kabir, M; Kerns, E; Nguyen, K; Shah, P; Sun, H; Wang, Y; Xu, X; Yu, KR | 1 |
| Kabir, M; Kerns, E; Neyra, J; Nguyen, K; Nguyễn, ÐT; Shah, P; Siramshetty, VB; Southall, N; Williams, J; Xu, X; Yu, KR | 1 |
| Lumelsky, NL; Schwartz, BS | 1 |
| Bertrand, R; Meyer, D; Sané, AT; Schmitt, E; Steyaert, A | 1 |
| Bertrand, R; Cimoli, G; Schmitt, E; Steyaert, A | 1 |
| Ayabe, H; Darzynkiwicz, Z; Hara, S; Tagawa, Y | 1 |
| Armstrong, RC; Flygare, J; Hellgren, D; Orsan, S; Wennborg, A | 1 |
| Bertrand, R; Sané, AT | 1 |
| Darzynkiewicz, Z; Dragan, M; Grabarek, J; Johnson, GL; Lee, BW | 1 |
| Caron, NS; Deng, Y; Ehrnhoefer, DE; Hayden, MR; Qiu, X; Tsang, M | 1 |
13 other study(ies) available for camptothecin and tosylphenylalanyl chloromethyl ketone
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Design, synthesis, and biological evaluation of callophycin A and analogues as potential chemopreventive and anticancer agents.
Topics: Antineoplastic Agents; Aromatase; Breast Neoplasms; Carbolines; Cell Line, Tumor; Cell Proliferation; Female; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Molecular Structure; NAD(P)H Dehydrogenase (Quinone); NF-kappa B; Nitric Oxide; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Tumor Necrosis Factor-alpha | 2011 |
Highly predictive and interpretable models for PAMPA permeability.
Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Humans; Models, Biological; Organic Chemicals; Regression Analysis; Support Vector Machine | 2017 |
Predictive models of aqueous solubility of organic compounds built on A large dataset of high integrity.
Topics: Drug Discovery; Organic Chemicals; Pharmaceutical Preparations; Solubility | 2019 |
Retrospective assessment of rat liver microsomal stability at NCATS: data and QSAR models.
Topics: Animals; Computer Simulation; Databases, Factual; Drug Discovery; High-Throughput Screening Assays; Liver; Machine Learning; Male; Microsomes, Liver; National Center for Advancing Translational Sciences (U.S.); Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Rats; Rats, Sprague-Dawley; Retrospective Studies; United States | 2020 |
Protease inhibitors induce specific changes in protein tyrosine phosphorylation that correlate with inhibition of apoptosis in myeloid cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Calcium-Calmodulin-Dependent Protein Kinases; Camptothecin; DNA, Neoplasm; HL-60 Cells; Humans; Nucleosomes; Phosphoric Monoester Hydrolases; Phosphorylation; Protease Inhibitors; Topoisomerase I Inhibitors; Tosylphenylalanyl Chloromethyl Ketone; Tyrosine | 1996 |
The CrmA- and TPCK-sensitive pathways that trigger oligonucleosome-sized DNA fragmentation in camptothecin-induced apoptosis: relation to caspase activation and high molecular weight DNA fragmentation.
Topics: Apoptosis; Camptothecin; Caspase 3; Caspases; Cysteine Endopeptidases; DNA Fragmentation; Enzyme Activation; Humans; Lymphoma, B-Cell; Molecular Weight; Nucleosomes; Serpins; Signal Transduction; Tosylphenylalanyl Chloromethyl Ketone; Tumor Cells, Cultured; Viral Proteins | 1997 |
Bcl-xL modulates apoptosis induced by anticancer drugs and delays DEVDase and DNA fragmentation-promoting activities.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-X Protein; Camptothecin; Cell-Free System; Cysteine Proteinase Inhibitors; DNA Fragmentation; Endopeptidases; Enzyme Activation; Humans; Leukemia, Promyelocytic, Acute; Oligopeptides; Peptide Hydrolases; Proto-Oncogene Proteins c-bcl-2; Serine Proteinase Inhibitors; Tosylphenylalanyl Chloromethyl Ketone; Transfection; Tumor Cells, Cultured | 1998 |
[Analysis of drug-induced apoptosis in human leukemic cell line (HL-60)].
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Azacitidine; Camptothecin; Cell Cycle; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Tosylphenylalanyl Chloromethyl Ketone | 1998 |
Proteolytic cleavage of HsRad51 during apoptosis.
Topics: Antibodies, Monoclonal; Apoptosis; Camptothecin; Cell Line, Transformed; Cell-Free System; Cysteine Proteinase Inhibitors; DNA Topoisomerases, Type I; DNA-Activated Protein Kinase; DNA-Binding Proteins; fas Receptor; Humans; Jurkat Cells; Nuclear Proteins; Oligopeptides; Poly(ADP-ribose) Polymerases; Protein Serine-Threonine Kinases; Rad51 Recombinase; Serine Proteinase Inhibitors; T-Lymphocytes; Tosylphenylalanyl Chloromethyl Ketone | 1998 |
Distinct steps in DNA fragmentation pathway during camptothecin-induced apoptosis involved caspase-, benzyloxycarbonyl- and N-tosyl-L-phenylalanylchloromethyl ketone-sensitive activities.
Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Caspase 3; Caspases; Cell Division; Cell Survival; Cell-Free System; Cysteine Endopeptidases; DNA Fragmentation; Humans; Protein Synthesis Inhibitors; Tosylphenylalanyl Chloromethyl Ketone; Tumor Cells, Cultured | 1998 |
Activation of chymotrypsin-like serine protease(s) during apoptosis detected by affinity-labeling of the enzymatic center with fluoresceinated inhibitor.
Topics: Affinity Labels; Amino Acid Chloromethyl Ketones; Apoptosis; Binding Sites; Camptothecin; Enzyme Activation; Flow Cytometry; Fluorescein; HL-60 Cells; Humans; Serine Endopeptidases; Serine Proteinase Inhibitors; Tosyllysine Chloromethyl Ketone; Tosylphenylalanyl Chloromethyl Ketone; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2002 |
Laquinimod decreases Bax expression and reduces caspase-6 activation in neurons.
Topics: Animals; Antineoplastic Agents, Phytogenic; bcl-2-Associated X Protein; Camptothecin; Caspase 6; Cerebral Cortex; COS Cells; Disease Models, Animal; Dose-Response Relationship, Drug; Down Syndrome; Gene Expression Regulation; Humans; Huntingtin Protein; Mice; Mice, Transgenic; Mutation; Neurons; Protein Synthesis Inhibitors; Quinolones; Time Factors; Tosylphenylalanyl Chloromethyl Ketone | 2016 |