camptothecin has been researched along with thymidine in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (43.33) | 18.7374 |
| 1990's | 7 (23.33) | 18.2507 |
| 2000's | 9 (30.00) | 29.6817 |
| 2010's | 1 (3.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Coetzee, ML; Klein, K; Ove, P; Sartiano, GP | 1 |
| Perdue, JF; Raizada, MK | 1 |
| Morais, R | 1 |
| Kono, A; Kuga, H; Sato, K; Shimazoe, T; Takeda, S | 1 |
| Aonuma, M; Hirota, Y; Kawato, Y; Kuga, H; Sato, K | 1 |
| Adams, DJ; Bair, KW; Elstein, KH; Zucker, RM | 1 |
| Mui, SC; Strauss, PR; Todt, JC; Zhang, LH | 1 |
| Tobey, RA | 1 |
| Crissman, HA; Tobey, RA | 1 |
| Rein, A; Rubinstein, L | 1 |
| Bosmann, HB; Morgan, HR; Myers, MW | 1 |
| Becker, Y; Ben-Zeev, A; Weinberg, E | 1 |
| Horwitz, MS; Horwitz, SB; Hsu, KC; Liebeskind, D | 1 |
| Bosmann, HB | 1 |
| Homan, ER; Neil, GL | 1 |
| Rajalakshmi, S; Sarma, DS | 1 |
| Kono, A; Matsuoka, H; Saito, T; Seo, Y; Takiguchi, S; Tomoda, H; Yano, K | 1 |
| Boorstein, RJ; Chiu, LN; Mahl, E; Mi, LJ | 1 |
| Arai, H; Fujii, N; Kasai, M; Nakano, H; Saito, H | 1 |
| Erusalimsky, JD; Hong, Y; John, J; Moore, M | 1 |
| Falck, J; Helin, K; Hofland, K; Jensen, PB; Petersen, BO; Sehested, M | 1 |
| Bigg, DC; Bronckart, Y; Chaboteaux, C; da Costa, PM; Decaestecker, C; Gordover, L; Harper, L; Kiss, R; Lavergne, O; Lesueur-Ginot, L; Malonne, H; Philippart, P | 1 |
| Mazaheri, K; Ng, CE; Payant, C; Raaphorst, GP | 1 |
| Bolderson, E; Helleday, T; Meuth, M; Mohindra, A; Stone, J; Wells, M | 1 |
| Antony, S; Gmeiner, WH; Kohlhagen, G; Liao, ZY; Pommier, Y; Sordet, O; Zhang, HL | 1 |
| Meuth, M; Rodriguez, R | 1 |
| Leu, YL; Prijovich, ZM; Roffler, SR | 1 |
| Chen, W; Cloughesy, T; Czernin, J; Delaloye, S; Geist, C; Lai, A; Phelps, ME; Pope, W; Satyamurthy, N; Sayre, J; Silverman, DH | 1 |
| Cox, A; Hansen, LT; Helleday, T; Meuth, M; Phear, G; Rodriguez, R; Scorah, J; Spang-Thomsen, M | 1 |
| Ayusawa, D; En, A; Fujii, M; Miki, K; Takauji, Y | 1 |
30 other study(ies) available for camptothecin and thymidine
| Article | Year |
|---|---|
The effect of several antitumor agents on 3H-TTP incorporation in host liver and hepatoma nuclei.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Camptothecin; Carcinoma, Hepatocellular; Cell Nucleus; Daunorubicin; DNA; DNA, Neoplasm; DNA, Single-Stranded; Doxorubicin; In Vitro Techniques; Liver; Liver Neoplasms; Male; Mitomycins; Neoplasms, Experimental; Plicamycin; Rats; Thymidine | 1977 |
Extent of mitogen receptor occupancy and modulation of mitogen receptor exposure: possible mechanisms for the regulation of cell growth.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Binding, Competitive; Biological Transport; Camptothecin; Cell Transformation, Neoplastic; Cells, Cultured; Culture Media; Cycloheximide; Deoxyadenosines; Deoxyglucose; DNA Replication; Insulin; Kinetics; Mitogens; Phosphoric Diester Hydrolases; Receptor, Insulin; Thymidine | 1976 |
Protein content and enzyme levels of cultured chick embryo cells treated with camptothecin and actinomycin D.
Topics: Animals; Camptothecin; Chick Embryo; Cytidine Triphosphate; Dactinomycin; Electron Transport Complex IV; Endonucleases; Fibroblasts; Leucine; Microsomes; Mitochondria; NADPH-Ferrihemoprotein Reductase; Phosphoric Monoester Hydrolases; Proteins; Succinate Dehydrogenase; Thymidine; Uridine | 1977 |
Camptothecin analog (CPT-11)-sensitive human pancreatic tumor cell line QGP-1N shows resistance to SN-38, an active metabolite of CPT-11.
Topics: Antineoplastic Agents, Phytogenic; Biological Transport; Camptothecin; Cell Division; DNA Replication; DNA Topoisomerases, Type I; Drug Resistance; Humans; Irinotecan; Pancreatic Neoplasms; Thymidine; Tumor Cells, Cultured | 1992 |
Intracellular roles of SN-38, a metabolite of the camptothecin derivative CPT-11, in the antitumor effect of CPT-11.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Survival; DNA Damage; DNA Replication; DNA, Single-Stranded; Irinotecan; Kinetics; Leukemia P388; Mice; RNA, Neoplasm; Thymidine; Topoisomerase I Inhibitors; Uridine | 1991 |
Polyploidy induction as a consequence of topoisomerase inhibition. A flow cytometric assessment.
Topics: Amsacrine; Animals; Camptothecin; Doxorubicin; Flow Cytometry; Friend murine leukemia virus; G2 Phase; Leukemia, Erythroblastic, Acute; Mice; Polyploidy; Teniposide; Thymidine; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1991 |
Role for topoisomerases in the release of DNA into the detergent-soluble fraction of eukaryotic cells.
Topics: Aminoacridines; Amsacrine; Animals; Camptothecin; Detergents; DNA; DNA Topoisomerases, Type I; Intercalating Agents; Kinetics; Mice; Novobiocin; Solubility; Spleen; Teniposide; Thymidine | 1986 |
Effects of cytosine arabinoside, daunomycin, mithramycin, azacytidine, adriamycin, and camptothecin on mammalian cell cycle traverse.
Topics: Animals; Antineoplastic Agents; Autoradiography; Azacitidine; Camptothecin; Cell Division; Cell Line; Cricetinae; Cytarabine; Daunorubicin; DNA; DNA Replication; Doxorubicin; Mitosis; Plicamycin; Thymidine; Tritium | 1972 |
Use of flow microfluorometry in detailed analysis of effects of chemical agents on cell cycle progression.
Topics: Animals; Antineoplastic Agents; Autoradiography; Bleomycin; Camptothecin; Cell Division; Cell Line; Cricetinae; Cytarabine; DNA Replication; Fluorometry; Hydroxyurea; Mitosis; Thymidine; Time Factors; Tritium | 1972 |
Effect of camptothecin on simian virus 40 DNA.
Topics: Animals; Camptothecin; Cell Line; Centrifugation, Density Gradient; DNA, Viral; Haplorhini; Kidney; Molecular Weight; Simian virus 40; Thymidine; Tritium | 1974 |
Synthesis of DNA, RNA protein and glycoprotein in mitochondria of cells transformed with Rous sarcoma viruses.
Topics: Animals; Avian Sarcoma Viruses; Camptothecin; Carbon Radioisotopes; Cell Transformation, Neoplastic; Chick Embryo; Cycloheximide; DNA, Neoplasm; Fibroblasts; Glucose; Glycoproteins; Leucine; Mannose; Mitochondria; Mutation; Neoplasm Proteins; Nucleoside Diphosphate Sugars; RNA, Neoplasm; Species Specificity; Temperature; Thymidine; Tritium; Uridine; Uridine Diphosphate Sugars | 1974 |
Isolation of herpes simplex virus DNA from virus particles and infected cells by electrophoresis in polyacrylamide gels.
Topics: Animals; Camptothecin; Carbon Radioisotopes; Cell Fractionation; Cell Line; Cell Nucleus; Centrifugation, Density Gradient; Cytarabine; Cytoplasm; DNA; DNA Replication; DNA, Viral; Electrophoresis, Polyacrylamide Gel; Haplorhini; Hydroxyurea; Kidney; Molecular Weight; Simplexvirus; Thymidine; Tritium | 1974 |
Immunoreactivity to antinucleoside antibodies in camptothecin treated HeLa cells.
Topics: Animals; Antibodies; Camptothecin; Cell Division; Cytosine; DNA, Single-Stranded; Fluorescence; HeLa Cells; Humans; Immunologic Techniques; Nucleic Acid Conformation; Nucleosides; Rabbits; Thymidine | 1974 |
Antineoplastic drug activity in the mitotic cycle--effects of six agents on macromolecular synthesis in synchronous mammalian leukemic cells.
Topics: Animals; Antineoplastic Agents; Asparaginase; Azaserine; Camptothecin; Culture Media; DNA, Neoplasm; Ethidium; Fucose; Glucosamine; Glycoproteins; Hydroxyurea; Leucine; Leukemia, Experimental; Mice; Mitosis; Neoplasm Proteins; RNA, Neoplasm; Thymidine; Time Factors; Tritium; Uridine | 1972 |
The effect of dose interval on the survival of L1210 leukemic mice treated with DNA synthesis inhibitors.
Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Division; Cell Survival; Cytarabine; DNA, Neoplasm; Formates; Hydroxyurea; Leukemia L1210; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Pyridines; Thiosemicarbazones; Thymidine; Time Factors | 1973 |
Rapid repair of hepatic DNA damage induced by camptothecin in the intact rat.
Topics: Animals; Camptothecin; Centrifugation, Density Gradient; DNA Repair; DNA, Single-Stranded; Liver; Male; Rats; Sucrose; Thymidine; Tritium | 1973 |
Cytotoxicity of CPT-11 for gastrointestinal cancer cells cultured on fixed-contact-sensitive plates.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Survival; Colony-Forming Units Assay; Gastrointestinal Neoplasms; Humans; Irinotecan; Mice; Mice, Inbred BALB C; Survival Analysis; Thymidine; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1995 |
Toxicity of camptothecin to Chinese hamster cells containing 5-hydroxymethyl-2'-deoxyuridine in their DNA.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Camptothecin; Cell Cycle; Cell Line; Cricetinae; Cricetulus; DNA Repair; Dose-Response Relationship, Drug; Drug Synergism; Irinotecan; Lung; Naphthoquinones; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; S Phase; Thymidine; Topoisomerase I Inhibitors | 1995 |
Induction of protein-DNA complexes in HeLa S3 cells by KW-2149, a new derivative of mitomycin C.
Topics: Antineoplastic Agents; Camptothecin; DNA, Neoplasm; Dose-Response Relationship, Drug; HeLa Cells; Humans; Kinetics; Mercaptoethanol; Mitomycin; Mitomycins; Molecular Structure; Neoplasm Proteins; Protein Binding; Structure-Activity Relationship; Thymidine | 1993 |
A glass fiber/diethylaminoethyl double filter binding assay that measures apoptotic internucleosomal DNA fragmentation.
Topics: Antineoplastic Agents; Apoptosis; Camptothecin; Chemistry Techniques, Analytical; DNA Fragmentation; Doxorubicin; Ethanolamines; Etoposide; Filtration; Glass; Humans; Microscopy, Fluorescence; Microscopy, Phase-Contrast; Nucleosomes; Thymidine; Tritium; Tumor Cells, Cultured | 1996 |
Differential cytotoxic pathways of topoisomerase I and II anticancer agents after overexpression of the E2F-1/DP-1 transcription factor complex.
Topics: Antineoplastic Agents; Apoptosis; Camptothecin; Carrier Proteins; Cell Cycle; Cell Cycle Proteins; Cell Survival; Cisplatin; DNA; DNA Damage; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA-Binding Proteins; DNA, Recombinant; DNA, Single-Stranded; E2F Transcription Factors; E2F1 Transcription Factor; Enzyme Inhibitors; Etoposide; Gene Expression Regulation, Neoplastic; Humans; Luciferases; Promoter Regions, Genetic; Recombinant Fusion Proteins; Retinoblastoma-Binding Protein 1; S Phase; Thymidine; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Transcription Factor DP1; Transcription Factors; Tumor Cells, Cultured | 2000 |
Homocamptothecin, an E-ring-modified camptothecin, exerts more potent antiproliferative activity than other topoisomerase I inhibitors in human colon cancers obtained from surgery and maintained in vitro under histotypical culture conditions.
Topics: Antineoplastic Agents; Biopsy; Camptothecin; Cell Division; Colon; Colonic Neoplasms; Culture Techniques; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Doxorubicin; Enzyme Inhibitors; Etoposide; Humans; Irinotecan; Thymidine; Topoisomerase I Inhibitors; Topotecan; Tritium; Tumor Cells, Cultured | 2000 |
Evaluation of cell survival, DNA double strand breaks, and DNA synthesis during concurrent camptothecin and X-radiation treatments.
Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Cell Survival; DNA; DNA Damage; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Enzyme Inhibitors; Humans; Thymidine; Tumor Cells, Cultured; X-Rays | 2001 |
A tumour-derived mutant allele of XRCC2 preferentially suppresses homologous recombination at DNA replication forks.
Topics: Base Pair Mismatch; Camptothecin; DNA; DNA Repair; DNA Replication; DNA-Binding Proteins; Female; Genes, Reporter; Humans; Leiomyosarcoma; Mitomycin; Mutation; Recombination, Genetic; Sarcoma; Thymidine; Tumor Cells, Cultured; Uterine Neoplasms | 2004 |
A novel polypyrimidine antitumor agent FdUMP[10] induces thymineless death with topoisomerase I-DNA complexes.
Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Death; DNA Damage; DNA Topoisomerases, Type I; DNA, Neoplasm; DNA, Single-Stranded; Drug Screening Assays, Antitumor; Fluorodeoxyuridylate; Fluorouracil; Leukemia P388; Mice; Quinazolines; Thiophenes; Thymidine; Thymidylate Synthase; Topoisomerase I Inhibitors | 2005 |
Chk1 and p21 cooperate to prevent apoptosis during DNA replication fork stress.
Topics: Apoptosis; Camptothecin; Cell Line, Tumor; Checkpoint Kinase 1; Checkpoint Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; DNA; DNA Repair; DNA Replication; Humans; Protein Kinases; Protein Serine-Threonine Kinases; Thymidine; Tumor Suppressor Protein p53 | 2006 |
Effect of pH and human serum albumin on the cytotoxicity of a glucuronide prodrug of 9-aminocamptothecin.
Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; DNA Fragmentation; Dose-Response Relationship, Drug; Glucuronidase; Glucuronides; Humans; Hybridomas; Hydrogen-Ion Concentration; Hydrolysis; Immunoconjugates; Inhibitory Concentration 50; Irinotecan; Lactones; Molecular Structure; Prodrugs; Serum Albumin; Thymidine; Time Factors; Topotecan; Tritium | 2007 |
Predicting treatment response of malignant gliomas to bevacizumab and irinotecan by imaging proliferation with [18F] fluorothymidine positron emission tomography: a pilot study.
Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Camptothecin; Cell Proliferation; Female; Fluorine Radioisotopes; Glioma; Humans; Irinotecan; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Pilot Projects; Positron-Emission Tomography; Prognosis; Prospective Studies; Radiography; Radiopharmaceuticals; Survival Rate; Thymidine | 2007 |
Thymidine selectively enhances growth suppressive effects of camptothecin/irinotecan in MSI+ cells and tumors containing a mutation of MRE11.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell Line, Tumor; Colonic Neoplasms; DNA-Binding Proteins; Humans; Irinotecan; Mice; Mice, Nude; Microsatellite Instability; MRE11 Homologue Protein; Mutation; Thymidine; Tumor Stem Cell Assay; Xenograft Model Antitumor Assays | 2008 |
Combinatorial effects of continuous protein synthesis, ERK-signaling, and reactive oxygen species on induction of cellular senescence.
Topics: Antioxidants; Butadienes; Camptothecin; Cell Size; Cellular Senescence; Cycloheximide; DNA Damage; HeLa Cells; Humans; MAP Kinase Signaling System; Nitriles; Protein Biosynthesis; Reactive Oxygen Species; Thymidine | 2016 |