Page last updated: 2024-08-22

camptothecin and thiazoles

camptothecin has been researched along with thiazoles in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.03)18.2507
2000's19 (57.58)29.6817
2010's12 (36.36)24.3611
2020's1 (3.03)2.80

Authors

AuthorsStudies
Bai, F; Hara, N; Kawasaki, M; Mizuno, K; Nakanishi, Y; Pei, XH; Takayama, K; Tsuruta, N1
Hotta, T; Ishimoto, K; Iwahashi, M; Matsuda, K; Tanaka, H; Tani, M; Tanimura, H; Tsunoda, T; Yamaue, H1
Kong, JY; Rabkin, SW1
Fukumoto, H; Kanzawa, F; Koh, Y; Koizumi, F; Nakamura, T; Nishio, K; Saijo, N; Tatsumi, Y; Yoshioka, T1
Akeshima, R; Iba, T; Itamochi, H; Kamazawa, S; Kanamori, Y; Kigawa, J; Sultana, H; Terakawa, N1
Chauvier, D; Kegelaer, G; Manfait, M; Morjani, H1
Boven, E; Hoogsteen, IJ; Kohlhagen, G; Maliepaard, M; Pinedo, HM; Pommier, Y; Scheffer, GL; Scheper, RJ; Schlüper, HM; van Hattum, AH1
Deguchi, N; Murai, M; Nonaka, S; Ueno, M; Yamazaki, R1
Culmsee, CW; Cutler, RG; Greig, NH; Holloway, HW; Lahiri, DK; Mattson, MP; Yu, QS; Zhu, X1
LaVoie, EJ; Li, D; Li, TK; Liu, A; Liu, LF; Sim, SP; Zhao, B1
Hiwasa, T; Iwadate, Y; Noda, A; Sakaida, T; Takiguchi, M; Uehara, M; Yamaji, S; Yamaura, A1
Inoue, H; Mori, M; Ohta, M; Sadanaga, N; Tanaka, F; Yamaguchi, H1
Akaike, T; Fang, J; Greish, K; Maeda, H; Sawa, T1
André, A; Braekman, JC; Bruyneel, F; Darro, F; Decaestecker, C; Dewelle, J; El Yazidi, M; Guissou, P; Kiss, R; Nacoulma, O; Simon, G; Tuti, J; Van Quaquebeke, E1
Chen, SZ; Jiang, M; Zhen, YS1
Feng, LF; Lei, XY; Liao, DF; Tang, SS; Zhong, M; Zhu, BY1
Fu, YR; Qiu, ZY; Yan, YR; Yi, ZJ1
An, L; Bao, Y; Hou, S; Lin, J; Lin, X; Liu, X1
Belkhiri, A; Castells, A; Correa, P; Dar, AA; El-Rifai, W; Koyama, T; Pera, M; Piazuelo, MB; Washington, K; Zaika, A1
Dadashzadeh, S; Derakhshandeh, K; Shirazi, FH1
Cusano, G; D'Incalci, M; Di Francesco, AM; Forestieri, D; Meco, D; Patriarca, V; Pisano, C; Riccardi, R; Servidei, T; Zucchetti, M1
Chang, PL; Feng, TH; Juang, HH; Lin, YF; Tsui, KH1
Dai, W; Li, HY; Liu, YQ; Yang, L1
Boos, J; Lanvers-Kaminsky, C; Spaniol, K1
Allen, JE; Brown, JM; Daniel, CJ; Dicker, DT; Dolloff, NG; Dorsey, JF; El-Deiry, WS; Furth, EE; Hart, LS; Jee, DI; Klein, PS; Kuribayashi, K; Liu, JJ; Liu, YY; Mayes, PA; Sears, RC1
DeSimone, JM; Finniss, M; Gullapalli, A; Luft, JC; Napier, ME; Pandya, A; Parrott, MC1
Du, J; Huang, C; Huang, S; Huang, W; Li, Y1
Covell, DG1
Huang, J; Mao, W; Shen, Y; Sui, M; Wang, J; Wu, X; Zhang, H1
Liu, W; Lu, M; Sun, B; Tang, X; Wu, L; Yan, Z; Yang, C; Zhou, H1
Jaggi, M; Joshi, V; Negi, LM; Ronodip, K; Talegaonkar, S1
Li, L; Li, Z; Liu, W; Pan, Y; Yang, C; Zhao, Y; Zhong, W; Zhou, H; Zhu, Y1
Lambertini, M; Punie, K1

Other Studies

33 other study(ies) available for camptothecin and thiazoles

ArticleYear
Effect of CPT-11 in combination with other anticancer agents in lung cancer cells.
    Anti-cancer drugs, 1997, Volume: 8, Issue:3

    Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Non-Small-Cell Lung; Cell Survival; Drug Interactions; Drug Screening Assays, Antitumor; Humans; Irinotecan; Lung Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured

1997
In vitro augmentation of antitumor effect in combination with CPT-11 and CDDP for human colorectal cancer.
    Journal of surgical oncology, 2000, Volume: 73, Issue:1

    Topics: Adenocarcinoma; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Colonic Neoplasms; Coloring Agents; Drug Synergism; Female; Humans; Irinotecan; Male; Middle Aged; Mitomycin; Rectal Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured

2000
Angiotensin II does not induce apoptosis but rather prevents apoptosis in cardiomyocytes.
    Peptides, 2000, Volume: 21, Issue:8

    Topics: Angiotensin II; Animals; Animals, Newborn; Apoptosis; Camptothecin; Cell Nucleus; Cell Separation; Cells, Cultured; Chick Embryo; Culture Media, Serum-Free; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Heart; In Situ Nick-End Labeling; Mice; Myocardium; Necrosis; Propidium; Staurosporine; Tetrazolium Salts; Thiazoles; Time Factors

2000
In vitro synergistic interactions between the cisplatin analogue nedaplatin and the DNA topoisomerase I inhibitor irinotecan and the mechanism of this interaction.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Division; DNA Topoisomerases, Type I; Drug Synergism; Enzyme Inhibitors; Humans; Irinotecan; Lung Neoplasms; Organoplatinum Compounds; Thiazoles; Thiazolidinediones; Topoisomerase I Inhibitors; Tumor Cells, Cultured

2001
Sensitivity to anticancer agents and resistance mechanisms in clear cell carcinoma of the ovary.
    Japanese journal of cancer research : Gann, 2002, Volume: 93, Issue:6

    Topics: Adenocarcinoma, Clear Cell; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Camptothecin; Cisplatin; Coloring Agents; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Etoposide; Female; Glutathione; Humans; Inhibitory Concentration 50; Irinotecan; Mitochondrial Proteins; Mitomycin; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Ovarian Neoplasms; Paclitaxel; Reverse Transcriptase Polymerase Chain Reaction; Ribosomal Proteins; RNA, Messenger; Saccharomyces cerevisiae Proteins; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured

2002
Reversal of multidrug resistance-associated protein-mediated daunorubicin resistance by camptothecin.
    Journal of pharmaceutical sciences, 2002, Volume: 91, Issue:8

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Camptothecin; Cell Line; Cell Nucleus; Chemokines, CC; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Humans; Leukemia; Microscopy, Confocal; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured

2002
Induction of breast cancer resistance protein by the camptothecin derivative DX-8951f is associated with minor reduction of antitumour activity.
    British journal of cancer, 2002, Sep-09, Volume: 87, Issue:6

    Topics: Acridines; Animals; Antigens, CD; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Camptothecin; Cell Division; DNA Topoisomerases, Type I; Drug Resistance, Neoplasm; Female; Humans; Immunoenzyme Techniques; Isoquinolines; Membrane Glycoproteins; Mice; Mice, Nude; Mutation; Neoplasm Proteins; Neoplasms, Experimental; Ovarian Neoplasms; Tetrahydroisoquinolines; Tetraspanin 29; Tetrazolium Salts; Thiazoles; Topoisomerase I Inhibitors; Tumor Cells, Cultured

2002
SN-38 induces cell cycle arrest and apoptosis in human testicular cancer.
    European urology, 2002, Volume: 42, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Camptothecin; Cell Cycle; Cell Line; Cisplatin; DNA; Etoposide; G1 Phase; Humans; In Situ Nick-End Labeling; Irinotecan; Male; Testicular Neoplasms; Tetrazolium Salts; Thiazoles

2002
Novel p53 inactivators with neuroprotective action: syntheses and pharmacological evaluation of 2-imino-2,3,4,5,6,7-hexahydrobenzothiazole and 2-imino-2,3,4,5,6,7-hexahydrobenzoxazole derivatives.
    Journal of medicinal chemistry, 2002, Nov-07, Volume: 45, Issue:23

    Topics: Animals; Apoptosis; Benzoxazoles; Camptothecin; Culture Techniques; Hippocampus; Imines; Ischemic Attack, Transient; Neuroprotective Agents; PC12 Cells; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thiazoles; Transcription Factors; Tumor Suppressor Protein p53

2002
2,3-Dimethoxybenzo[i]phenanthridines: topoisomerase I-targeting anticancer agents.
    Bioorganic & medicinal chemistry, 2003, Feb-20, Volume: 11, Issue:4

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; DNA; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Indicators and Reagents; Phenanthridines; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Topoisomerase I Inhibitors; Tumor Cells, Cultured

2003
Acquisition of drug resistance by constitutive suppression of NF-kappaB in ras-transformed NIH3T3 mouse fibroblasts.
    International journal of oncology, 2003, Volume: 23, Issue:4

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Blotting, Western; Camptothecin; Cell Line, Transformed; Cell Nucleus; Cell Survival; Coloring Agents; DNA; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Fibroblasts; Flow Cytometry; Mice; Mitomycin; NF-kappa B; NIH 3T3 Cells; Peplomycin; Tetrazolium Salts; Thiazoles; Transfection

2003
Stimulation of CD40 inhibits Fas- or chemotherapy-mediated apoptosis and increases cell motility in human gastric carcinoma cells.
    International journal of oncology, 2003, Volume: 23, Issue:6

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Carcinoma; CD40 Antigens; CD40 Ligand; Cell Division; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Survival; fas Receptor; Flow Cytometry; Humans; Stomach Neoplasms; Tetrazolium Salts; Thiazoles

2003
Enhancement of chemotherapeutic response of tumor cells by a heme oxygenase inhibitor, pegylated zinc protoporphyrin.
    International journal of cancer, 2004, Volume: 109, Issue:1

    Topics: Animals; Annexin A5; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Body Weight; Camptothecin; Cell Line, Tumor; Cisplatin; Coloring Agents; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Etoposide; Heme Oxygenase (Decyclizing); Humans; Hydrogen Peroxide; Male; Metalloporphyrins; Mice; Mitomycin; Neoplasms; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxygen; Polyethylene Glycols; Proline; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles

2004
Identification of a novel cardenolide (2''-oxovoruscharin) from Calotropis procera and the hemisynthesis of novel derivatives displaying potent in vitro antitumor activities and high in vivo tolerance: structure-activity relationship analyses.
    Journal of medicinal chemistry, 2005, Feb-10, Volume: 48, Issue:3

    Topics: Animals; Antineoplastic Agents; Calotropis; Camptothecin; Cardenolides; Cell Line, Tumor; Cell Proliferation; Cerebral Cortex; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Etoposide; Humans; Irinotecan; Magnetic Resonance Spectroscopy; Maximum Tolerated Dose; Mice; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Sodium-Potassium-Exchanging ATPase; Structure-Activity Relationship; Swine; Thiazoles

2005
HERG K+ channel expression-related chemosensitivity in cancer cells and its modulation by erythromycin.
    Cancer chemotherapy and pharmacology, 2005, Volume: 56, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Biomarkers; Breast Neoplasms; Camptothecin; Carcinoma; Colonic Neoplasms; Coloring Agents; Drug Interactions; Drug Resistance, Neoplasm; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Gene Expression Profiling; Humans; Lung Neoplasms; Paclitaxel; Potassium Channels, Voltage-Gated; Tetrazolium Salts; Thiazoles; Transfection; Vincristine

2005
Bcl-2 siRNA induced apoptosis and increased sensitivity to 5-fluorouracil and HCPT in HepG2 cells.
    Journal of drug targeting, 2006, Volume: 14, Issue:1

    Topics: Antimetabolites, Antineoplastic; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Camptothecin; Caspase 3; Caspases; Cell Line, Tumor; Drug Delivery Systems; Drug Synergism; Flow Cytometry; Fluorouracil; Genes, bcl-2; Humans; Liver Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Tetrazolium Salts; Thiazoles

2006
Hydroxycamptothecin-induced apoptosis in hepatoma SMMC-7721 cells and the role of mitochondrial pathway.
    Mitochondrion, 2006, Volume: 6, Issue:4

    Topics: Apoptosis; Apoptosis Inducing Factor; Camptothecin; Cell Line, Tumor; Cell Survival; Cytochromes c; Cytoplasm; DNA Fragmentation; Enzyme Inhibitors; Hepatocytes; Humans; Membrane Potential, Mitochondrial; Mitochondria; Tetrazolium Salts; Thiazoles

2006
Effects of isocamptothecin, a novel camptothecin analogue, on proliferation, apoptosis and telomerase activity in HaCaT cells.
    Experimental dermatology, 2008, Volume: 17, Issue:6

    Topics: Analysis of Variance; Apoptosis; Camptotheca; Camptothecin; Cell Line; Cell Proliferation; DNA; Down-Regulation; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Growth Inhibitors; Humans; Isomerism; Keratinocytes; Polymerase Chain Reaction; Psoriasis; Telomerase; Tetrazolium Salts; Thiazoles

2008
Frequent overexpression of Aurora Kinase A in upper gastrointestinal adenocarcinomas correlates with potent antiapoptotic functions.
    Cancer, 2008, Apr-15, Volume: 112, Issue:8

    Topics: Adenocarcinoma; Apoptosis; Aurora Kinase A; Aurora Kinases; Biomarkers, Tumor; Blotting, Western; Camptothecin; Coloring Agents; Cytochromes c; Enzyme Inhibitors; Esophageal Neoplasms; Flow Cytometry; Gene Expression Regulation, Enzymologic; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Luciferases; Luminescent Agents; Polymerase Chain Reaction; Protein Array Analysis; Protein Serine-Threonine Kinases; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53

2008
9-nitrocamptothecin polymeric nanoparticles: cytotoxicity and pharmacokinetic studies of lactone and total forms of drug in rats.
    Anti-cancer drugs, 2008, Volume: 19, Issue:8

    Topics: Animals; Antineoplastic Agents; Area Under Curve; Camptothecin; Cell Line, Tumor; Cell Survival; Humans; Injections, Intravenous; Lactones; Male; Nanoparticles; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles

2008
Antitumor activity and pharmacokinetics of oral gimatecan on pediatric cancer xenografts.
    Cancer chemotherapy and pharmacology, 2010, Volume: 66, Issue:4

    Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Area Under Curve; Camptothecin; Cell Line, Tumor; Cell Proliferation; Child; Chromatography, High Pressure Liquid; Half-Life; Humans; Irinotecan; Male; Mice; Mice, Nude; Neuroblastoma; Rhabdomyosarcoma; Tetrazolium Salts; Thiazoles; Xenograft Model Antitumor Assays

2010
p53 downregulates the gene expression of mitochondrial aconitase in human prostate carcinoma cells.
    The Prostate, 2011, Jan-01, Volume: 71, Issue:1

    Topics: Aconitate Hydratase; Camptothecin; Carcinoma; Cell Line, Tumor; Down-Regulation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Male; Mitochondria; Mutation; Prostatic Neoplasms; Response Elements; Thiazoles; Tumor Suppressor Protein p53

2011
Design and synthesis of novel camptothecin/5-fluorouracil conjugates as cytotoxic agents.
    Natural product research, 2011, Volume: 25, Issue:19

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Cytotoxins; Drug Synergism; Fluorouracil; Humans; Inhibitory Concentration 50; Lactones; Mice; Molecular Structure; Tetrazolium Salts; Thiazoles

2011
An in-vitro evaluation of the polo-like kinase inhibitor GW843682X against paediatric malignancies.
    Anti-cancer drugs, 2011, Volume: 22, Issue:6

    Topics: Antineoplastic Agents; ATP-Binding Cassette Transporters; Benzimidazoles; Blotting, Western; Camptothecin; Caspases; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; Child; Coloring Agents; Enzyme Activation; Enzyme Inhibitors; Humans; Neoplasms; Polo-Like Kinase 1; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; RNA, Messenger; Tetrazolium Salts; Thiazoles; Thiophenes; Topoisomerase I Inhibitors

2011
Overcoming hypoxia-induced apoptotic resistance through combinatorial inhibition of GSK-3β and CDK1.
    Cancer research, 2011, Aug-01, Volume: 71, Issue:15

    Topics: Adenocarcinoma; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Camptothecin; CDC2 Protein Kinase; Cell Hypoxia; Cell Line, Tumor; Colonic Neoplasms; Drug Synergism; Fluorouracil; Gene Expression Regulation, Neoplastic; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Inhibitor of Apoptosis Proteins; Irinotecan; Mice; Mice, Nude; Neoplasm Proteins; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-myb; Pyrimidines; Recombinant Proteins; RNA, Small Interfering; Thiazoles; TNF-Related Apoptosis-Inducing Ligand; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays

2011
Incorporation and controlled release of silyl ether prodrugs from PRINT nanoparticles.
    Journal of the American Chemical Society, 2012, May-09, Volume: 134, Issue:18

    Topics: Antineoplastic Agents; Apoptosis; Camptothecin; Cell Line, Tumor; Dasatinib; Delayed-Action Preparations; Deoxycytidine; Ethers; Gemcitabine; Humans; Nanoparticles; Neoplasms; Prodrugs; Pyrimidines; Silanes; Thiazoles

2012
Screening of anti-cancer agent using zebrafish: comparison with the MTT assay.
    Biochemical and biophysical research communications, 2012, May-25, Volume: 422, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Biphenyl Compounds; Camptothecin; Cell Line, Tumor; Coloring Agents; Dimethyl Sulfoxide; Drug Screening Assays, Antitumor; Emodin; Gene Expression; Humans; Lignans; Naphthoquinones; Rotenone; Tetrazolium Salts; Thiazoles; Transcriptional Activation; Tumor Suppressor Protein p53; Zebrafish

2012
Integrating constitutive gene expression and chemoactivity: mining the NCI60 anticancer screen.
    PloS one, 2012, Volume: 7, Issue:10

    Topics: Algorithms; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cluster Analysis; Colchicine; Computational Biology; Cyclin-Dependent Kinases; Dasatinib; Databases, Genetic; Fluorouracil; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Neoplasms; Oligonucleotide Array Sequence Analysis; Paclitaxel; Pimozide; Purines; Pyrimidines; Terfenadine; Thiazoles; Tubulin Modulators; Verapamil

2012
Novel SN38 conjugate-forming nanoparticles as anticancer prodrug: in vitro and in vivo studies.
    Journal of controlled release : official journal of the Controlled Release Society, 2013, Mar-10, Volume: 166, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Camptothecin; Cell Cycle; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Drug Stability; Female; Humans; Irinotecan; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Mice, Nude; Micelles; Nanoparticles; Prodrugs; Solubility; Tetrazolium Salts; Thiazoles; Xenograft Model Antitumor Assays

2013
1,2-benzisothiazol-3-one derivatives as a novel class of small-molecule caspase-3 inhibitors.
    Bioorganic & medicinal chemistry, 2014, Apr-15, Volume: 22, Issue:8

    Topics: Apoptosis; Benzothiazoles; Binding Sites; Camptothecin; Caspase 3; Caspase Inhibitors; Catalytic Domain; Humans; Jurkat Cells; Molecular Docking Simulation; Morpholines; Static Electricity; Thiazoles

2014
Hyaluronic acid decorated lipid nanocarrier for MDR modulation and CD-44 targeting in colon adenocarcinoma.
    International journal of biological macromolecules, 2015, Volume: 72

    Topics: Adenocarcinoma; Camptothecin; Colonic Neoplasms; Coumarins; Drug Delivery Systems; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Hyaluronan Receptors; Hyaluronic Acid; Irinotecan; Lipids; Nanoparticles; Thiazoles

2015
Synthesis and evaluation of N-acyl-substituted 1,2-benzisothiazol-3-one derivatives as caspase-3 inhibitors.
    Bioorganic & medicinal chemistry, 2014, Dec-15, Volume: 22, Issue:24

    Topics: Apoptosis; Binding Sites; Camptothecin; Caspase 3; Caspase 7; Caspase Inhibitors; Catalytic Domain; Humans; Jurkat Cells; Molecular Docking Simulation; Protein Binding; Structure-Activity Relationship; Thiazoles

2014
ESMO20 YO for YO: highlights on new drugs in advanced breast cancer focusing on sacituzumab govitecan and alpelisib.
    ESMO open, 2021, Volume: 6, Issue:1

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Breast Neoplasms; Camptothecin; Female; Humans; Immunoconjugates; Thiazoles

2021