Page last updated: 2024-08-22

camptothecin and sucrose

camptothecin has been researched along with sucrose in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19904 (30.77)18.7374
1990's0 (0.00)18.2507
2000's1 (7.69)29.6817
2010's8 (61.54)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Asher, Y; Becker, Y1
Kessel, D; Spataro, A1
Abelson, HT; Penman, S1
Rajalakshmi, S; Sarma, DS1
Butler, RN; Davidson, GP; Howarth, GS; Tooley, KL1
Chen, LT; Dito, E; Ko, AH; Lin, YL; Ong, A; Shan, YS; Su, WC; Tempero, MA; Wang, YW; Yeh, CG1
Saif, MW1
Calderon, RI; Cruz, RE; Drummond, DC; Fitzgerald, JB; Hall, CP; Hindle, A; Kang, MH; Ko, W; Lee, JS; Makena, MR; Paz, N; Reynolds, CP; Song, MM; Triche, TJ; Wang, J1
Liu, M1
Carnevale, J; Ko, AH1
André, T; Arbaud, C; Bachet, JB; Bennamoun, M; Bonnetain, F; Brusquant, D; Chibaudel, B; de Gramont, A; Dupuis, O; Garcia, ML; Hammel, P; Khalil, A; Larsen, AK; Louvet, C; Maindrault-Gœbel, F; Tournigand, C; Wang, YW; Yeh, CG1
Chang, JY; Chen, LT; Chiang, NJ; Shan, YS1

Reviews

2 review(s) available for camptothecin and sucrose

ArticleYear
MM-398 (nanoliposomal irinotecan): emergence of a novel therapy for the treatment of advanced pancreatic cancer.
    Future oncology (London, England), 2016, Volume: 12, Issue:4

    Topics: Animals; Antineoplastic Agents; Camptothecin; Clinical Trials as Topic; Drug Combinations; Drug Discovery; Drug Evaluation, Preclinical; Humans; Neoplasm Staging; Pancreatic Neoplasms; Sucrose; Treatment Outcome

2016
Development of nanoliposomal irinotecan (nal-IRI, MM-398, PEP02) in the management of metastatic pancreatic cancer.
    Expert opinion on pharmacotherapy, 2016, Volume: 17, Issue:10

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Disease-Free Survival; Drug Combinations; Fluorouracil; Humans; Leucovorin; Pancreatic Neoplasms; Sucrose; Treatment Outcome

2016

Trials

3 trial(s) available for camptothecin and sucrose

ArticleYear
A multinational phase 2 study of nanoliposomal irinotecan sucrosofate (PEP02, MM-398) for patients with gemcitabine-refractory metastatic pancreatic cancer.
    British journal of cancer, 2013, Aug-20, Volume: 109, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Camptothecin; Disease-Free Survival; Drug Combinations; Female; Humans; Irinotecan; Liposomes; Male; Middle Aged; Pancreatic Neoplasms; Salvage Therapy; Sucrose; Treatment Outcome

2013
MM-398 achieves primary endpoint of overall survival in phase III study in patients with gemcitabine refractory metastatic pancreatic cancer.
    JOP : Journal of the pancreas, 2014, May-27, Volume: 15, Issue:3

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Deoxycytidine; Drug Combinations; Drug Resistance, Neoplasm; Gemcitabine; Humans; Pancreatic Neoplasms; Sucrose

2014
PEPCOL: a GERCOR randomized phase II study of nanoliposomal irinotecan PEP02 (MM-398) or irinotecan with leucovorin/5-fluorouracil as second-line therapy in metastatic colorectal cancer.
    Cancer medicine, 2016, Volume: 5, Issue:4

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Combined Modality Therapy; Drug Combinations; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Male; Middle Aged; Neoplasm Metastasis; Quality of Life; Retreatment; Sucrose; Treatment Outcome

2016

Other Studies

8 other study(ies) available for camptothecin and sucrose

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
In vitro synthesis of DNA in nuclei isolated from herpes simplex virus-infected cells, untreated and treated with metabolic inhibitors.
    Virology, 1975, Volume: 63, Issue:1

    Topics: Adenine Nucleotides; Animals; Anti-Bacterial Agents; Camptothecin; Cell Line; Cell Nucleus; Centrifugation, Density Gradient; Culture Media; Cytarabine; Cytosine Nucleotides; Deoxyadenosines; DNA; DNA, Viral; Guanine Nucleotides; Haplorhini; Hydroxyurea; Kidney; Magnesium; Simplexvirus; Sucrose; Thymine Nucleotides; Tritium; Virus Replication

1975
The effects of camptothecin on mammalian DNA.
    Biochimica et biophysica acta, 1973, Dec-07, Volume: 331, Issue:2

    Topics: Animals; Camptothecin; Carbon Radioisotopes; Cell Line; Centrifugation, Density Gradient; DNA; Formamides; Hydrogen-Ion Concentration; L Cells; Leukemia, Lymphoid; Mammals; Mice; Molecular Weight; Spectrophotometry, Ultraviolet; Sucrose

1973
Induction of alkali labile links in cellular DNA by camptothecin.
    Biochemical and biophysical research communications, 1973, Feb-20, Volume: 50, Issue:4

    Topics: Alkalies; Camptothecin; Carbon Isotopes; Centrifugation, Density Gradient; DNA Repair; DNA, Neoplasm; DNA, Single-Stranded; Formamides; HeLa Cells; Hydrogen-Ion Concentration; Nucleic Acid Denaturation; Sucrose

1973
Rapid repair of hepatic DNA damage induced by camptothecin in the intact rat.
    Biochemical and biophysical research communications, 1973, Aug-21, Volume: 53, Issue:4

    Topics: Animals; Camptothecin; Centrifugation, Density Gradient; DNA Repair; DNA, Single-Stranded; Liver; Male; Rats; Sucrose; Thymidine; Tritium

1973
A non-invasive method for detection of intestinal mucositis induced by different classes of chemotherapy drugs in the rat.
    Cancer biology & therapy, 2006, Volume: 5, Issue:9

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breath Tests; Camptothecin; Cyclophosphamide; Disease Models, Animal; DNA Topoisomerases, Type I; Doxorubicin; Etoposide; Female; Intestine, Small; Irinotecan; Mucositis; Rats; Sucrase; Sucrose; Topoisomerase I Inhibitors

2006
Activity of MM-398, nanoliposomal irinotecan (nal-IRI), in Ewing's family tumor xenografts is associated with high exposure of tumor to drug and high SLFN11 expression.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2015, Mar-01, Volume: 21, Issue:5

    Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Disease Models, Animal; Drug Combinations; Female; Gene Expression; Humans; Irinotecan; Liposomes; Macrophages; Mice; Nuclear Proteins; Sarcoma, Ewing; Sucrose; Tissue Distribution; Tumor Burden; Xenograft Model Antitumor Assays

2015
Market watch: Upcoming market catalysts in Q4 2015.
    Nature reviews. Drug discovery, 2015, Volume: 14, Issue:10

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Camptothecin; Clinical Trials as Topic; Drug Approval; Drug Combinations; Drug Design; Humans; Sucrose; United States; United States Food and Drug Administration

2015