Page last updated: 2024-08-22

camptothecin and rottlerin

camptothecin has been researched along with rottlerin in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's5 (71.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Bharate, SB; Bhushan, S; Gupta, BD; Jain, SK; Meena, S; Pathania, AS; Sharma, A; Sharma, R; Singh, B; Vishwakarma, RA1
Chen, GQ; Cheng, JK; Shen, SM; Wang, LS; Wu, YL; Yu, Y1
Chen, CS; Guh, JH; Ho, YF; Hsu, JL; Hsu, LC; Li, TK1
Cai, JJ; Imperato-McGinley, J; Tan, C; Wang, G; Wang, LP; Wang, X; Zhu, YS1

Other Studies

7 other study(ies) available for camptothecin and rottlerin

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
Semisynthesis of mallotus B from rottlerin: evaluation of cytotoxicity and apoptosis-inducing activity.
    Journal of natural products, 2013, Sep-27, Volume: 76, Issue:9

    Topics: Acetophenones; Antineoplastic Agents; Benzopyrans; Cell Cycle; Cell Division; Drug Screening Assays, Antitumor; Hep G2 Cells; HL-60 Cells; Humans; Mallotus Plant; Molecular Structure; Phloroglucinol

2013
Downregulation of ANP32B, a novel substrate of caspase-3, enhances caspase-3 activation and apoptosis induction in myeloid leukemic cells.
    Carcinogenesis, 2010, Volume: 31, Issue:3

    Topics: Acetophenones; Antineoplastic Agents; Apoptosis; Benzopyrans; Camptothecin; Carcinoma; Caspase 3; Cell Line, Tumor; Cysteine Proteinase Inhibitors; Down-Regulation; Enzyme Activation; Female; Humans; Leukemia, Myeloid; Male; Neoplasm Proteins; Neoplasms; Nuclear Proteins; Recombinant Fusion Proteins; RNA Interference; RNA, Small Interfering; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity

2010
Rottlerin potentiates camptothecin-induced cytotoxicity in human hormone refractory prostate cancers through increased formation and stabilization of topoisomerase I-DNA cleavage complexes in a PKCĪ“-independent pathway.
    Biochemical pharmacology, 2012, Jul-01, Volume: 84, Issue:1

    Topics: Acetophenones; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzopyrans; Blotting, Western; Camptothecin; Cell Culture Techniques; Cell Line, Tumor; Cell Survival; DNA Cleavage; DNA Topoisomerases, Type I; Drug Synergism; Flow Cytometry; Humans; In Situ Nick-End Labeling; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Protein Kinase C-delta; RNA, Small Interfering; Topoisomerase I Inhibitors; Transfection

2012
Dual action of NSC606985 on cell growth and apoptosis mediated through PKCĪ“ in prostatic cancer cells.
    International journal of oncology, 2017, Volume: 51, Issue:5

    Topics: Acetophenones; Apoptosis; Benzopyrans; Camptothecin; Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Humans; Male; Precision Medicine; Prostatic Neoplasms; Protein Kinase C-delta

2017