Page last updated: 2024-08-22

camptothecin and rotenone

camptothecin has been researched along with rotenone in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (60.00)29.6817
2010's4 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H1
Asao, Y; Matsuda, H; Miyagawa, K; Nakashima, S; Takayama, S; Xu, F; Yoshida, K; Yoshikawa, M1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Johnson, DA; Johnson, JA; Li, J; Spletter, ML; Svendsen, CN; Wright, LS1
Biswas, SC; Greene, LA; Jackson-Lewis, V; Malagelada, C; Ryu, EJ1
Bito, T; Fabian, G; Farago, N; Feher, LZ; Katona, RL; Kitajka, K; Kulin, S; Nagy, LI; Puskas, LG; Tiszlavicz, L; Tubak, V1
Du, J; Huang, C; Huang, S; Huang, W; Li, Y1

Other Studies

10 other study(ies) available for camptothecin and rotenone

ArticleYear
Identifying off-target effects and hidden phenotypes of drugs in human cells.
    Nature chemical biology, 2006, Volume: 2, Issue:6

    Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship

2006
Rotenoids and flavonoids with anti-invasion of HT1080, anti-proliferation of U937, and differentiation-inducing activity in HL-60 from Erycibe expansa.
    Bioorganic & medicinal chemistry, 2007, Feb-01, Volume: 15, Issue:3

    Topics: Cell Differentiation; Cell Proliferation; Convolvulaceae; Enzyme Precursors; Fibrosarcoma; Flavonoids; Gelatinases; HL-60 Cells; Humans; Matrix Metalloproteinase 9; Metalloendopeptidases; Neoplasm Invasiveness; Plant Extracts; Rotenone; Tumor Cells, Cultured; U937 Cells

2007
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Rotenone-induced caspase 9/3-independent and -dependent cell death in undifferentiated and differentiated human neural stem cells.
    Journal of neurochemistry, 2005, Volume: 92, Issue:3

    Topics: Adenosine Triphosphate; Camptothecin; Caspase 3; Caspase 9; Caspases; Cell Death; Cell Differentiation; Cells, Cultured; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Humans; In Situ Nick-End Labeling; Models, Biological; Neurons; Reactive Oxygen Species; Rotenone; Stem Cells; Topoisomerase I Inhibitors; Uncoupling Agents

2005
RTP801 is elevated in Parkinson brain substantia nigral neurons and mediates death in cellular models of Parkinson's disease by a mechanism involving mammalian target of rapamycin inactivation.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Sep-27, Volume: 26, Issue:39

    Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis; Camptothecin; DNA-Binding Proteins; Gene Expression Regulation; Humans; Hydrogen Peroxide; Male; Melanins; Mice; Mice, Inbred C57BL; MPTP Poisoning; Nerve Growth Factor; Neurons; Oxidopamine; Parkinsonian Disorders; PC12 Cells; Phosphorylation; Protein Kinases; Protein Processing, Post-Translational; Rats; Repressor Proteins; Ribosomal Protein S6 Kinases, 70-kDa; RNA; RNA Interference; Rotenone; Signal Transduction; Substantia Nigra; TOR Serine-Threonine Kinases; Transcription Factors; Transcription, Genetic; Transfection; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins; Tunicamycin

2006
High-density real-time PCR-based in vivo toxicogenomic screen to predict organ-specific toxicity.
    International journal of molecular sciences, 2011, Volume: 12, Issue:9

    Topics: Aniline Compounds; Animals; Antineoplastic Agents; Brain; Camptothecin; Coumarins; Doxorubicin; Female; Heart; Irinotecan; Kidney; Mice, Inbred BALB C; Myocardium; Phenylenediamines; Real-Time Polymerase Chain Reaction; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; Rotenone; Sulfasalazine; Toxicogenetics; Transcriptome; Xenobiotics

2011
Screening of anti-cancer agent using zebrafish: comparison with the MTT assay.
    Biochemical and biophysical research communications, 2012, May-25, Volume: 422, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Biphenyl Compounds; Camptothecin; Cell Line, Tumor; Coloring Agents; Dimethyl Sulfoxide; Drug Screening Assays, Antitumor; Emodin; Gene Expression; Humans; Lignans; Naphthoquinones; Rotenone; Tetrazolium Salts; Thiazoles; Transcriptional Activation; Tumor Suppressor Protein p53; Zebrafish

2012