Page last updated: 2024-08-22

camptothecin and rosettacin

camptothecin has been researched along with rosettacin in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cinelli, MA; Cushman, M; Dexheimer, TS; Morrell, A; Pommier, Y; Scher, ES1
Cinelli, MA; Cordero, B; Cushman, M; Dexheimer, TS; Pommier, Y1
Agama, K; Agrawal, S; Cinelli, MA; Cushman, M; Dexheimer, TS; Morrell, AE; Pommier, Y1

Other Studies

3 other study(ies) available for camptothecin and rosettacin

ArticleYear
Design, synthesis, and biological evaluation of 14-substituted aromathecins as topoisomerase I inhibitors.
    Journal of medicinal chemistry, 2008, Aug-14, Volume: 51, Issue:15

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; DNA; DNA Topoisomerases, Type I; Drug Design; Humans; Indolizines; Ligands; Models, Molecular; Molecular Structure; Protein Binding; Quinolines; Structure-Activity Relationship; Topoisomerase I Inhibitors

2008
Synthesis and biological evaluation of 14-(aminoalkyl-aminomethyl)aromathecins as topoisomerase I inhibitors: investigating the hypothesis of shared structure-activity relationships.
    Bioorganic & medicinal chemistry, 2009, Oct-15, Volume: 17, Issue:20

    Topics: Antineoplastic Agents; Drug Evaluation, Preclinical; Enzyme Inhibitors; Magnetic Resonance Spectroscopy; Models, Molecular; Structure-Activity Relationship; Topoisomerase I Inhibitors

2009
The structure-activity relationships of A-ring-substituted aromathecin topoisomerase I inhibitors strongly support a camptothecin-like binding mode.
    Bioorganic & medicinal chemistry, 2010, Aug-01, Volume: 18, Issue:15

    Topics: Antineoplastic Agents; Camptothecin; DNA Topoisomerases, Type I; Enzyme Inhibitors; Humans; Isoquinolines; Models, Molecular; Protein Binding; Structure-Activity Relationship; Topoisomerase I Inhibitors

2010