camptothecin has been researched along with quercetin in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (8.00) | 18.2507 |
| 2000's | 10 (40.00) | 29.6817 |
| 2010's | 11 (44.00) | 24.3611 |
| 2020's | 2 (8.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bodo, B; Cosson, JP; Jossang, A; Provost, J; Sévenet, T; Zahir, A | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bordignon, A; Cieckiewicz, E; Di Giovanni, N; Frédérich, M; Hoareau, F; Illien, B; Jansen, O; Ledoux, A; Marvilliers, A; Pendeville, H; Quetin-Leclercq, J; St-Gelais, A | 1 |
| Agafonova, NA; Borisevich, SS; Burgart, YV; Chupakhin, ON; Evstigneeva, NP; Gerasimova, NA; Krasnykh, OP; Kungurov, NV; Kushch, SO; Makhaeva, GF; Maslova, VV; Rudakova, EV; Saloutin, VI; Shchegolkov, EV; Solodnikov, SY; Triandafilova, GA; Ulitko, MV; Zilberberg, NV | 1 |
| Holzer, G; Karlseder, J; Orel, L; Simon, MM; Sliutz, G; Tempfer, C | 1 |
| Lee, CH; Tsai, TH; Yeh, PH | 1 |
| Ikegami, Y; Ishikawa, T; Mitomo, H; Sano, K; Sawada, S; Yoshida, H; Yoshikawa, M | 1 |
| Cain, A; Li, S; Long, M; Taylor, J; Wang, B; Zhang, Z | 1 |
| Coombs, GH; Goyeneche, D; Jean-Moreno, V; Rojas, R; Walker, J | 1 |
| Das, BB; Dasgupta, SB; Dinda, B; Ganguly, A; Majumder, HK; Mohanta, BC; Roy, A; Sen, N | 1 |
| Cao, J; Chan, E; Chen, X; Duan, W; Hu, ZP; Huang, M; Wen, JY; Yang, XX; Yu, XQ; Zhou, SF | 1 |
| Basic, I; Benkovic, V; Bevanda, M; Brozovic, G; Dikic, D; Horvat Knezevic, A; Knezevic, F; Orsolic, N | 1 |
| Awasthi, A; Bansal, T; Jaggi, M; Khar, RK; Talegaonkar, S | 1 |
| Benković, V; Dikić, D; Karabeg, S; Knežević, AH; Kopjar, N; Lisičić, D; Oršolić, N | 1 |
| Fadlalla, K; Katkoori, V; Manne, U; Mosley, L; Samuel, T; Turner, T | 1 |
| Ding, LL; Dou, W; Zhang, JJ | 1 |
| Castelli, S; D'Annessa, I; Desideri, A | 1 |
| Guo, Q; Yuan, Q | 1 |
| Bao, Y; Guo, L; Ji, F; Li, Y; Tang, Q; Wang, J | 1 |
| Hou, YC; Lei, CS; Lin, MT; Pai, MH; Yeh, SL | 1 |
| Doğanlar, O; Doğanlar, ZB; Güçlü, O; Yüksel, V | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
1 review(s) available for camptothecin and quercetin
| Article | Year |
|---|---|
Topoisomerase 1B as a target against leishmaniasis.
Topics: Antiprotozoal Agents; Camptothecin; DNA Topoisomerases, Type I; Humans; Indoles; Isoquinolines; Leishmania; Leishmaniasis; Naphthoquinones; Protozoan Proteins; Quercetin | 2015 |
24 other study(ies) available for camptothecin and quercetin
| Article | Year |
|---|---|
DNA topoisomerase I inhibitors: cytotoxic flavones from Lethedon tannaensis.
Topics: Animals; Antineoplastic Agents, Phytogenic; Flavonoids; Humans; KB Cells; Leukemia P388; Magnetic Resonance Spectroscopy; Mice; New Caledonia; Plants, Medicinal; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Topoisomerase I Inhibitors | 1996 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Antimalarial Activities of Alkyl Cyclohexenone Derivatives Isolated from the Leaves of Poupartia borbonica.
Topics: Anacardiaceae; Animals; Antimalarials; Belgium; Cyclohexanones; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Flavonoids; HeLa Cells; Humans; Inhibitory Concentration 50; Malaria; Mice; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Parasitic Sensitivity Tests; Plant Leaves; Plasmodium berghei; Plasmodium falciparum; Quercetin; Zebrafish | 2017 |
Multiple biological active 4-aminopyrazoles containing trifluoromethyl and their 4-nitroso-precursors: Synthesis and evaluation.
Topics: Animals; Bacteria; Drug Screening Assays, Antitumor; Epidermophyton; HeLa Cells; Humans; Mice; Microbial Sensitivity Tests; Molecular Structure; Nitroso Compounds; Pyrazoles; Rats, Sprague-Dawley; Structure-Activity Relationship; Trichophyton | 2020 |
Drug resistance against gemcitabine and topotecan mediated by constitutive hsp70 overexpression in vitro: implication of quercetin as sensitiser in chemotherapy.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell Division; Deoxycytidine; Drug Interactions; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Fibrosarcoma; Gemcitabine; HSP70 Heat-Shock Proteins; Humans; Mice; Quercetin; Topotecan; Transfection; Tumor Cells, Cultured | 1996 |
Effect of P-glycoprotein modulators on the pharmacokinetics of camptothecin using microdialysis.
Topics: Animals; Antineoplastic Agents, Phytogenic; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B; Bile; Blood-Brain Barrier; Brain; Camptothecin; Flavanones; Flavonoids; Male; Microdialysis; Models, Biological; Quercetin; Rats; Rats, Sprague-Dawley | 2001 |
Transport of SN-38 by the wild type of human ABC transporter ABCG2 and its inhibition by quercetin, a natural flavonoid.
Topics: Adenosine Triphosphate; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Camptothecin; Cell Membrane; Cells, Cultured; Drug Resistance; Glucuronides; Humans; Irinotecan; Mutation; Neoplasm Proteins; Quercetin | 2004 |
Antifungal activity of camptothecin, trifolin, and hyperoside isolated from Camptotheca acuminata.
Topics: Alternaria; Ascomycota; Camptotheca; Camptothecin; Fungicides, Industrial; Fusarium; Plant Leaves; Plants; Quercetin | 2005 |
Leishmania donovani: differential activities of classical topoisomerase inhibitors and antileishmanials against parasite and host cells at the level of DNA topoisomerase I and in cytotoxicity assays.
Topics: Acid Phosphatase; Animals; Antimony Sodium Gluconate; Antiprotozoal Agents; Benzimidazoles; Berberine Alkaloids; Bisbenzimidazole; Camptothecin; Cell Line; Diminazene; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Leishmania donovani; Luciferases, Firefly; Luminescent Agents; Macrophages; Monocytes; Pentamidine; Quercetin; Topoisomerase I Inhibitors | 2006 |
Differential induction of Leishmania donovani bi-subunit topoisomerase I-DNA cleavage complex by selected flavones and camptothecin: activity of flavones against camptothecin-resistant topoisomerase I.
Topics: Animals; Camptothecin; DNA; DNA Topoisomerases, Type I; Enzyme Inhibitors; Flavanones; Flavonoids; Leishmania donovani; Luteolin; Mutation; Protein Subunits; Protozoan Proteins; Quercetin | 2006 |
A mechanistic study on altered pharmacokinetics of irinotecan by St. John's wort.
Topics: Animals; Anthracenes; Antineoplastic Agents, Phytogenic; Bridged Bicyclo Compounds; Camptothecin; Cell Line, Tumor; Cell Proliferation; Glucuronides; Hypericum; Irinotecan; Male; Microsomes, Liver; Perylene; Phloroglucinol; Plant Extracts; Quercetin; Rats; Rats, Sprague-Dawley; Terpenes | 2007 |
Enhanced antitumor activity of irinotecan combined with propolis and its polyphenolic compounds on Ehrlich ascites tumor in mice.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma, Ehrlich Tumor; Drug Synergism; Drug Therapy, Combination; Flavanones; Flavonoids; Irinotecan; Male; Mice; Phenols; Polyphenols; Propolis; Quercetin | 2007 |
Pre-clinical evidence for altered absorption and biliary excretion of irinotecan (CPT-11) in combination with quercetin: possible contribution of P-glycoprotein.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bile; Biological Availability; Biological Transport; Caco-2 Cells; Camptothecin; Drug Screening Assays, Antitumor; Female; Humans; Intestinal Absorption; Irinotecan; Quercetin; Rats; Rats, Wistar | 2008 |
Synergistic effects of irinotecan and flavonoids on Ehrlich ascites tumour-bearing mice.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma, Ehrlich Tumor; Comet Assay; DNA Damage; Dose-Response Relationship, Drug; Drug Synergism; Flavanones; Hepatocytes; Injections, Intraperitoneal; Irinotecan; Kidney; Male; Mice; Peritoneal Cavity; Quercetin | 2011 |
Dual-mode interaction between quercetin and DNA-damaging drugs in cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Camptothecin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cyclin B1; Cyclin-Dependent Kinase Inhibitor p21; DNA Damage; Drug Synergism; Etoposide; Flow Cytometry; Fluorouracil; Humans; Inhibitor of Apoptosis Proteins; Male; Prostatic Neoplasms; Quercetin; Survivin; Tumor Stem Cell Assay; Tumor Suppressor Protein p53 | 2012 |
[Effects of isorhamnetin on CYP3A4 and herb-drug interaction].
Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Cell Proliferation; Cytochrome P-450 CYP3A; Dose-Response Relationship, Drug; Hep G2 Cells; Herb-Drug Interactions; Humans; Irinotecan; Pregnane X Receptor; Quercetin; Receptors, Steroid; RNA, Messenger; Transcriptional Activation; Up-Regulation | 2012 |
A novel 10-hydroxycamptothecin-glucoside from the fruit of Camptotheca acuminata.
Topics: Camptotheca; Camptothecin; Carbohydrates; Carbolines; Fruit; Furans; Glucosides; Glycosides; Hydrolysis; Lignans; Magnetic Resonance Spectroscopy; Quercetin; Spectrometry, Mass, Electrospray Ionization | 2016 |
Quercetin exerts synergetic anti-cancer activity with 10-hydroxy camptothecin.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Camptothecin; Cell Cycle; Cell Line, Tumor; DNA Topoisomerases, Type I; Drug Synergism; Female; Humans; Membrane Potential, Mitochondrial; Mice, Nude; Neoplasms; Quercetin; Topoisomerase I Inhibitors; Tumor Burden; Xenograft Model Antitumor Assays | 2017 |
Effects of quercetin combined with anticancer drugs on metastasis-associated factors of gastric cancer cells: in vitro and in vivo studies.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Camptothecin; Cell Line, Tumor; Cell Survival; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; Injections, Intraperitoneal; Irinotecan; Mice, Nude; Neoplasm Proteins; Quercetin; Random Allocation; Specific Pathogen-Free Organisms; Stomach Neoplasms; Topoisomerase I Inhibitors; Tumor Burden; Xenograft Model Antitumor Assays | 2018 |
FOLFIRI-Mediated Toxicity in Human Aortic Smooth Muscle Cells and Possible Amelioration with Curcumin and Quercetin.
Topics: Antineoplastic Combined Chemotherapy Protocols; Aorta; Apoptosis; Apoptosis Regulatory Proteins; Camptothecin; Cells, Cultured; Curcumin; DNA Damage; Fluorouracil; Humans; Leucovorin; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Necrosis; Oxidative Stress; Quercetin; Signal Transduction | 2020 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |