Compounds > camptothecin
Page last updated: 2024-08-22

camptothecin and probenecid

camptothecin has been researched along with probenecid in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Ahmed, F; Cook, T; Gupta, E; Rubin, E; Sinko, P; Vyas, V1
Horikawa, M; Kato, Y; Sugiyama, Y1
Chung, SJ; Kim, DD; Kim, IW; Namkoong, EM; Shim, CK1
Kawabe, Y; Mori, N; Murakami, T; Yokooji, T1

Other Studies

6 other study(ies) available for camptothecin and probenecid

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Pharmacokinetics of orally administered camptothecins.
    Annals of the New York Academy of Sciences, 2000, Volume: 922

    Topics: Administration, Oral; Anion Transport Proteins; Antineoplastic Agents, Phytogenic; Biological Transport, Active; Biotransformation; Caco-2 Cells; Camptothecin; Carrier Proteins; Cell Membrane Permeability; Colonic Neoplasms; Enzyme Inhibitors; Humans; Hydrolysis; Intestinal Absorption; Intestinal Mucosa; Irinotecan; Liver; Liver Neoplasms; Probenecid; Prodrugs; Rectal Neoplasms

2000
Reduced gastrointestinal toxicity following inhibition of the biliary excretion of irinotecan and its metabolites by probenecid in rats.
    Pharmaceutical research, 2002, Volume: 19, Issue:9

    Topics: Animals; Bile; Camptothecin; Digestive System; Dose-Response Relationship, Drug; Drug Interactions; Irinotecan; Male; Probenecid; Rats; Rats, Sprague-Dawley

2002
Effect of probenecid on the biliary excretion of belotecan.
    Archives of pharmacal research, 2007, Volume: 30, Issue:11

    Topics: Animals; Bile; Biological Transport; Caco-2 Cells; Camptothecin; Humans; Male; Membrane Transport Proteins; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Probenecid; Rats

2007
Effect of genistein, a natural soy isoflavone, on the pharmacokinetics and intestinal toxicity of irinotecan hydrochloride in rats.
    The Journal of pharmacy and pharmacology, 2013, Volume: 65, Issue:2

    Topics: Alkaline Phosphatase; Animals; Biliary Tract; Body Weight; Camptothecin; Diarrhea; Drug Interactions; Genistein; Glucuronates; Glucuronides; Intestinal Mucosa; Intestines; Irinotecan; Kidney; Liver; Male; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Probenecid; Rats; Rats, Sprague-Dawley

2013