Page last updated: 2024-08-22

camptothecin and phenanthrenes

camptothecin has been researched along with phenanthrenes in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's0 (0.00)18.2507
2000's2 (16.67)29.6817
2010's7 (58.33)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Adamson, RH; Mead, JA; Sieber, SM1
Chung, C; Fidler, JM; Gao, M; Li, K; Rosen, GD; Ross, JA; Wei, K1
Cho, WJ; Kwon, Y; Lee, KT; Lee, SH; Van, HT; Yang, SH1
Li, FQ; Wang, W; Xie, XY; Yang, SW; Zhu, WP1
CalabrĂ², V; Malanga, M; Montariello, D; Quesada, P; Troiano, A1
Atsumi, Y; Fujimori, H; Inase, A; Kanno, M; Masutani, M; Nakagama, H; Osawa, T; Sakasai, R; Saya, H; Sugihara, E; Tashiro, F; Teraoka, H; Yoshioka, K1
Chan, RL; Cho, CH; Hu, T; Li, M; Lu, L; Shen, J; To, KK; Wang, L; Yeung, JH; Zhang, L1
Chai, K; Jiang, K; Li, F; Meng, G; Wang, W; Yang, S1
Alsaied, O; Arora, N; Banerjee, S; Dauer, P; Dudeja, V; Giri, B; Majumder, K; Modi, S; Saluja, A; Von Hoff, D1
Ding, Y; Gao, W; Li, D; Sun, Y; Wang, T; Wang, Z; Wei, J; Yang, Y1
Dhanasekaran, DN; Han, Y; Jo, H; Kim, H; Kim, S; Kim, SJ; Lee, J; Song, YS; Wang, W; Yang, KM1
Chovancova, B; Kajsik, M; Krizanova, O; Liskova, V; Roller, L1

Reviews

2 review(s) available for camptothecin and phenanthrenes

ArticleYear
Pharmacology of antitumor agents from higher plants.
    Cancer treatment reports, 1976, Volume: 60, Issue:8

    Topics: Animals; Antineoplastic Agents, Phytogenic; Aporphines; Camptothecin; Carcinoma, Squamous Cell; Chemical Phenomena; Chemistry; Etoposide; Humans; Leukemia L1210; Leukemia, Experimental; Leukemia, Lymphoid; Maytansine; Melanoma; Naphthoquinones; Nasopharyngeal Neoplasms; Neoplasms; Neoplasms, Experimental; Phenanthrenes; Structure-Activity Relationship; Teniposide; Vinblastine; Vincristine

1976
Phytochemicals in Cancer Immune Checkpoint Inhibitor Therapy.
    Biomolecules, 2021, 07-27, Volume: 11, Issue:8

    Topics: Animals; Antigens, CD; Antineoplastic Agents; B7 Antigens; B7-H1 Antigen; Camptothecin; CTLA-4 Antigen; Diterpenes; Epoxy Compounds; Flavonoids; Hepatitis A Virus Cellular Receptor 2; Humans; Immune Checkpoint Inhibitors; Immunotherapy; Isothiocyanates; Lymphocyte Activation Gene 3 Protein; Mice; Neoplasms; Phenanthrenes; Phytochemicals; Plant Extracts; Programmed Cell Death 1 Receptor; Receptors, Immunologic; Saponins; Sulfoxides; Terpenes; Tumor Microenvironment

2021

Other Studies

10 other study(ies) available for camptothecin and phenanthrenes

ArticleYear
PG490-88, a derivative of triptolide, causes tumor regression and sensitizes tumors to chemotherapy.
    Molecular cancer therapeutics, 2003, Volume: 2, Issue:9

    Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Cycle; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Diterpenes; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Inhibitors; Epoxy Compounds; Humans; Irinotecan; Lung Neoplasms; Mice; Mice, Nude; Phenanthrenes; Transplantation, Heterologous; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2003
Molecular design, synthesis and docking study of benz[b]oxepines and 12-oxobenzo[c]phenanthridinones as topoisomerase 1 inhibitors.
    Bioorganic & medicinal chemistry letters, 2009, May-01, Volume: 19, Issue:9

    Topics: Antineoplastic Agents; Benzoxepins; Camptothecin; Cell Line, Tumor; Chemistry, Pharmaceutical; DNA Topoisomerases, Type I; Drug Design; Drug Screening Assays, Antitumor; Enzyme Inhibitors; HeLa Cells; Humans; Models, Chemical; Molecular Conformation; Phenanthrenes; Protein Binding; Topoisomerase I Inhibitors

2009
In vitro synergistic cytotoxic effect of triptolide combined with hydroxycamptothecin on pancreatic cancer cells.
    The American journal of Chinese medicine, 2011, Volume: 39, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Caspase 3; Caspase 9; Cell Line, Tumor; Diterpenes; Drug Synergism; Epoxy Compounds; Humans; NF-kappa B; Pancreatic Neoplasms; Phenanthrenes; Phytotherapy; Plant Extracts; Signal Transduction; Tripterygium

2011
p63 involvement in poly(ADP-ribose) polymerase 1 signaling of topoisomerase I-dependent DNA damage in carcinoma cells.
    Biochemical pharmacology, 2013, Apr-01, Volume: 85, Issue:7

    Topics: Apoptosis; Camptothecin; Cell Line, Tumor; Cell Proliferation; DNA Damage; DNA Repair; DNA Topoisomerases, Type I; Drug Interactions; Humans; Phenanthrenes; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Prostaglandins, Synthetic; Signal Transduction; Topotecan; Transcription Factors; Tumor Suppressor Protein p53; Tumor Suppressor Proteins

2013
The Arf/p53 protein module, which induces apoptosis, down-regulates histone H2AX to allow normal cells to survive in the presence of anti-cancer drugs.
    The Journal of biological chemistry, 2013, May-10, Volume: 288, Issue:19

    Topics: Animals; Antineoplastic Agents; Apoptosis; Camptothecin; Cell Shape; Cells, Cultured; Cellular Senescence; Cisplatin; Cyclin-Dependent Kinase Inhibitor p16; DNA Damage; DNA Replication; Down-Regulation; Doxorubicin; Drug Resistance, Neoplasm; Gene Knockdown Techniques; Histones; Humans; Hydroxyurea; Mice; Mice, Knockout; Mutation; Phenanthrenes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Tumor Suppressor Protein p53

2013
Reversal of P-glycoprotein (P-gp) mediated multidrug resistance in colon cancer cells by cryptotanshinone and dihydrotanshinone of Salvia miltiorrhiza.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2014, Sep-25, Volume: 21, Issue:11

    Topics: Abietanes; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; Caco-2 Cells; Camptothecin; Digoxin; Doxorubicin; Drugs, Chinese Herbal; Furans; Gene Expression Regulation, Neoplastic; Humans; Irinotecan; Phenanthrenes; Quinones; Salvia miltiorrhiza

2014
Combination treatment with triptolide and hydroxycamptothecin synergistically enhances apoptosis in A549 lung adenocarcinoma cells through PP2A-regulated ERK, p38 MAPKs and Akt signaling pathways.
    International journal of oncology, 2015, Volume: 46, Issue:3

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Calcineurin; Camptothecin; Cell Line, Tumor; Diterpenes; Drug Synergism; Epoxy Compounds; Extracellular Signal-Regulated MAP Kinases; Humans; Irinotecan; Lung Neoplasms; p38 Mitogen-Activated Protein Kinases; Phenanthrenes; Proto-Oncogene Proteins c-akt; Signal Transduction

2015
Downregulation of Sp1 by Minnelide leads to decrease in HSP70 and decrease in tumor burden of gastric cancer.
    PloS one, 2017, Volume: 12, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Camptothecin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Diterpenes; Down-Regulation; Epoxy Compounds; Gene Expression Regulation, Neoplastic; HSP70 Heat-Shock Proteins; Humans; Irinotecan; Mice, Nude; Organophosphates; Phenanthrenes; Prodrugs; Reverse Transcriptase Polymerase Chain Reaction; Sp1 Transcription Factor; Stomach Neoplasms; Tumor Burden; Xenograft Model Antitumor Assays

2017
Synergistic antitumour effects of triptolide plus 10-hydroxycamptothecin onbladder cancer.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 115

    Topics: Animals; Antineoplastic Agents; Apoptosis; Camptothecin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Diterpenes; Drug Synergism; Epoxy Compounds; Mice, Inbred BALB C; Mice, Nude; Phenanthrenes; Reactive Oxygen Species; Urinary Bladder Neoplasms; Xenograft Model Antitumor Assays

2019
Camptothecin, triptolide, and apoptosis inducer kit have differential effects on mitochondria in colorectal carcinoma cells.
    FEBS open bio, 2022, Volume: 12, Issue:5

    Topics: Apoptosis; Camptothecin; Colorectal Neoplasms; Diterpenes; Epoxy Compounds; Humans; Mitochondria; Phenanthrenes

2022