camptothecin has been researched along with pegamotecan in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Conover, CD; Gilbert, CW; Greenwald, RB; Pendri, A; Shum, KL | 1 |
| Boro, M; Choe, YH; Greenwald, RB; Guan, S; Lee, C; Pendri, A; Sai, P; Zhao, H | 1 |
| Carlisle, R; Goetz, A; Kwiatek, J; Posey, JA; Rizzo, J; Rowinsky, EK; Rudoltz, MS; Saif, MW; Simmons, P; Stevenson, S; Takimoto, CH; Tolcher, AW | 1 |
| Ajani, JA; Benson, AB; Evans, TR; Falk, S; Mena, RR; Mulcahy, MF; Picus, J; Scott, LC; Thomas, AL; Wright, J; Yao, JC | 1 |
| Chen, HL; Cheng, PL; Gao, WJ; Goto, M; Lee, KH; Liu, YQ; Morris-Natschke, SL; Song, ZL; Wang, MJ; Wang, YH; Zhu, GX | 1 |
| Chen, FM; Cheng, TC; Cheng, TL; Chuang, CH; Fang, YP; Hsieh, YC; Huang, CC; Huang, MY; Lin, WW; Tsai, MJ; Tsai, TH; Tsai, YH; Wu, PC | 1 |
| Dai, Q; Fan, W; He, Q; Kong, L; Li, Z; Liao, Y; Long, S; Ren, Y; Wan, C; Yu, W; Zhang, Z; Zhu, R | 1 |
2 trial(s) available for camptothecin and pegamotecan
| Article | Year |
|---|---|
Phase 1 study of weekly polyethylene glycol-camptothecin in patients with advanced solid tumors and lymphomas.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Camptothecin; Dose-Response Relationship, Drug; Female; Humans; Lymphoma; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Polyethylene Glycols; Time Factors | 2005 |
A phase II study of pegylated-camptothecin (pegamotecan) in the treatment of locally advanced and metastatic gastric and gastro-oesophageal junction adenocarcinoma.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Camptothecin; Drug Administration Schedule; Esophagogastric Junction; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Staging; Polyethylene Glycols; Quality of Life; Stomach Neoplasms; Treatment Outcome | 2009 |
5 other study(ies) available for camptothecin and pegamotecan
| Article | Year |
|---|---|
Camptothecin delivery systems: enhanced efficacy and tumor accumulation of camptothecin following its conjugation to polyethylene glycol via a glycine linker.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Colorectal Neoplasms; Drug Carriers; Glycine; Humans; Injections, Intraperitoneal; Injections, Intravenous; Mice; Mice, Nude; Neoplasm Transplantation; Polyethylene Glycols; Prodrugs; Tissue Distribution; Tritium | 1998 |
20-O-acylcamptothecin derivatives: evidence for lactone stabilization.
Topics: Acylation; Antineoplastic Agents, Phytogenic; Camptothecin; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Lactones; Magnetic Resonance Spectroscopy; Polyethylene Glycols; Prodrugs; Spectrophotometry, Ultraviolet; Trees | 2000 |
Design and synthesis of novel PEG-conjugated 20(S)-camptothecin sulfonylamidine derivatives with potent in vitro antitumor activity via Cu-catalyzed three-component reaction.
Topics: Antineoplastic Agents; Camptothecin; Catalysis; Cell Line, Tumor; Cell Proliferation; Copper; Drug Design; Drug Screening Assays, Antitumor; Humans; Irinotecan; KB Cells; Polyethylene Glycols; Structure-Activity Relationship | 2015 |
Development of pH-Sensitive Cationic PEGylated Solid Lipid Nanoparticles for Selective Cancer-Targeted Therapy.
Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Cell Proliferation; Drug Delivery Systems; Humans; Lipids; Mice; Mice, Nude; Nanoparticles; Particle Size; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Xenograft Model Antitumor Assays | 2017 |
ROS-cleavable diselenide nanomedicine for NIR-controlled drug release and on-demand synergistic chemo-photodynamic therapy.
Topics: Camptothecin; Cell Line, Tumor; Delayed-Action Preparations; Drug Liberation; Humans; Nanomedicine; Nanoparticles; Neoplasms; Photochemotherapy; Photosensitizing Agents; Reactive Oxygen Species | 2022 |