camptothecin has been researched along with nutlin-3a in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Becker, K; Marchenko, ND; Maurice, M; Moll, UM | 1 |
| Abolmaali, ND; Tokalov, SV | 1 |
| Dudgeon, DD; Giuliano, KA; Johnston, PA; Lazo, JS; Shinde, SN; Shun, TY; Strock, CJ; Taylor, DL | 1 |
| Bhattacharya, S; Johnson, LR; Ray, RM | 1 |
| Chang, J; Davis-Dusenbery, BN; Gu, W; Hata, A; Jiang, X; Kashima, R; Lagna, G; Louie, J; Marathe, N; Sessa, R | 1 |
| Gdowicz-Kłosok, A; Krześniak, M; Rusin, M; Zajkowicz, A; Łasut, B | 1 |
6 other study(ies) available for camptothecin and nutlin-3a
| Article | Year |
|---|---|
Hyperubiquitylation of wild-type p53 contributes to cytoplasmic sequestration in neuroblastoma.
Topics: Active Transport, Cell Nucleus; Camptothecin; Cell Compartmentation; Cell Line, Tumor; Cytoplasm; Drug Synergism; Enzyme Inhibitors; Humans; Imidazoles; Neuroblastoma; Neurons; Peptide Fragments; Piperazines; Tumor Suppressor Protein p53; Ubiquitin; Ubiquitin Thiolesterase; Ubiquitin-Specific Peptidase 7 | 2007 |
Protection of p53 wild type cells from taxol by nutlin-3 in the combined lung cancer treatment.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Camptothecin; Cell Line, Tumor; Drug Screening Assays, Antitumor; Flow Cytometry; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Lung Neoplasms; Models, Genetic; Mutation; Piperazines; Purines; Roscovitine; Tumor Suppressor Protein p53 | 2010 |
Characterization and optimization of a novel protein-protein interaction biosensor high-content screening assay to identify disruptors of the interactions between p53 and hDM2.
Topics: Antineoplastic Agents; Biosensing Techniques; Camptothecin; Cell Line, Tumor; Checkpoint Kinase 2; Ellipticines; Genes, p53; High-Throughput Screening Assays; Humans; Imidazoles; Mitoxantrone; Piperazines; Protein Binding; Protein Interaction Mapping; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-mdm2; Recombinant Fusion Proteins; Small Molecule Libraries; Spectrometry, Fluorescence; Topotecan; Tumor Suppressor Protein p53 | 2010 |
Mdm2 inhibition induces apoptosis in p53 deficient human colon cancer cells by activating p73- and E2F1-mediated expression of PUMA and Siva-1.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Caco-2 Cells; Camptothecin; Caspases; Cell Line, Transformed; Colonic Neoplasms; DNA Fragmentation; DNA-Binding Proteins; E2F1 Transcription Factor; Gene Expression; Humans; Imidazoles; Nuclear Proteins; Piperazines; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-mdm2; RNA, Small Interfering; Tumor Protein p73; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2011 |
Acetylation of p53 stimulates miRNA processing and determines cell survival following genotoxic stress.
Topics: Acetylation; Apoptosis Regulatory Proteins; Camptothecin; Cell Survival; DNA Damage; HCT116 Cells; Histone Acetyltransferases; Humans; Imidazoles; MicroRNAs; Piperazines; Promoter Regions, Genetic; Ribonuclease III; RNA Processing, Post-Transcriptional; Tumor Suppressor Protein p53 | 2013 |
PIM2 survival kinase is upregulated in a p53-dependent manner in cells treated with camptothecin or co-treated with actinomycin D and nutlin-3a.
Topics: Amino Acid Sequence; Apoptosis; bcl-Associated Death Protein; Camptothecin; Cell Line, Tumor; Dactinomycin; Drug Synergism; Gene Knockdown Techniques; Humans; Imidazoles; Intercellular Signaling Peptides and Proteins; Nerve Tissue Proteins; Phosphorylation; Piperazines; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; RNA, Long Noncoding; RNA, Messenger; Serine; Topoisomerase I Inhibitors; Tumor Suppressor Protein p53; Up-Regulation | 2018 |