Page last updated: 2024-08-22

camptothecin and nsc606985

camptothecin has been researched along with nsc606985 in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (72.73)29.6817
2010's3 (27.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, GQ; Fliegauf, M; Lu, Y; Lübbert, M; Song, MG; Xu, YB; Yuan, TT1
Chen, GQ; Guo, M; Liu, W; Yu, Y; Zhu, YS1
Chen, GQ; Shen, SM; Wang, LS; Xia, L; Yu, Y; Zhang, L; Zhu, YS1
Cai, LQ; Chen, GQ; Imperato-McGinley, J; Qiao, Y; Tan, C; Wu, W; Zhu, YS1
Chen, GQ; Duan, XF; Wen, DH; Zhao, M1
Chen, GQ; Cheng, JK; Han, YH; Liao, SH; Wang, LS; Wang, XL; Xia, L; Zheng, Y1
Chen, G; Di, W; Xia, L; Yu, Y; Zhang, H; Zhang, N; Zheng, Y; Zhu, Y1
Chen, GQ; Huang, Y; Wang, LS; Yu, Y; Yuan, TT; Zhou, CX; Zhuang, HY1
Chen, GQ; Cheng, JK; Shen, SM; Wang, LS; Wu, YL; Yu, Y1
Fu, P; Imperato-McGinley, J; Tang, Z; Wang, G; Wang, L; Wang, X; Yu, R; Zhao, Y; Zhu, YS1
Cai, JJ; Imperato-McGinley, J; Tan, C; Wang, G; Wang, LP; Wang, X; Zhu, YS1

Other Studies

11 other study(ies) available for camptothecin and nsc606985

ArticleYear
Inducible expression of AML1-ETO fusion protein endows leukemic cells with susceptibility to extrinsic and intrinsic apoptosis.
    Leukemia, 2006, Volume: 20, Issue:6

    Topics: Antibodies, Monoclonal; Apoptosis; Blotting, Western; Camptothecin; Cell Line, Tumor; Core Binding Factor Alpha 2 Subunit; Cycloheximide; Ecdysterone; fas Receptor; Flow Cytometry; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Humans; Oncogene Proteins, Fusion; Receptors, Tumor Necrosis Factor; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RUNX1 Translocation Partner 1 Protein; Sensitivity and Specificity; Time Factors; Ultraviolet Rays

2006
Therapeutic efficacy of NSC606985, a novel camptothecin analog, in a mouse model of acute promyelocytic leukemia.
    Leukemia research, 2007, Volume: 31, Issue:11

    Topics: Animals; Antineoplastic Agents; Apoptosis; Camptothecin; Disease Models, Animal; Leukemia, Promyelocytic, Acute; Mice

2007
Subcellular proteome analysis of camptothecin analogue NSC606985-treated acute myeloid leukemic cells.
    Journal of proteome research, 2007, Volume: 6, Issue:9

    Topics: Apoptosis; Camptothecin; Cell Line, Tumor; Electrophoresis, Gel, Two-Dimensional; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Myeloid, Acute; Protein Kinase C-delta; Proteome; Proteomics; Subcellular Fractions

2007
NSC606985, a novel camptothecin analog, induces apoptosis and growth arrest in prostate tumor cells.
    Cancer chemotherapy and pharmacology, 2009, Volume: 63, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Camptothecin; Caspase 3; Caspase 7; Cell Line, Tumor; Cell Proliferation; Cytochromes c; DNA Fragmentation; Flow Cytometry; Humans; Male; Prostatic Neoplasms

2009
PU.1, a novel caspase-3 substrate, partially contributes to chemotherapeutic agents-induced apoptosis in leukemic cells.
    Biochemical and biophysical research communications, 2009, May-08, Volume: 382, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Aspartic Acid; Camptothecin; Caspase 3; Caspase Inhibitors; Cell Line, Tumor; Cysteine Proteinase Inhibitors; Etoposide; Humans; Leukemia; Mutagenesis, Site-Directed; Oligopeptides; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; RNA, Small Interfering; Trans-Activators

2009
NDRG1 is down-regulated in the early apoptotic event induced by camptothecin analogs: the potential role in proteolytic activation of PKC delta and apoptosis.
    Proteomics, 2009, Volume: 9, Issue:8

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Cell Cycle Proteins; Down-Regulation; Doxorubicin; Enzyme Activation; Humans; Intracellular Signaling Peptides and Proteins; Irinotecan; Protein Kinase C-delta; RNA, Small Interfering; Topotecan; Transcription, Genetic; U937 Cells

2009
NSC606985 induces apoptosis, exerts synergistic effects with cisplatin, and inhibits hypoxia-stabilized HIF-1alpha protein in human ovarian cancer cells.
    Cancer letters, 2009, Jun-18, Volume: 278, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Camptothecin; Caspase 3; Cell Line, Tumor; Cisplatin; Drug Synergism; Female; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Ovarian Neoplasms; Protein Kinase C-delta

2009
Nuclear translocation of dihydrofolate reductase is not a pre-requisite for DNA damage induced apoptosis.
    Apoptosis : an international journal on programmed cell death, 2009, Volume: 14, Issue:5

    Topics: Amino Acid Sequence; Apoptosis; Camptothecin; Caspase 3; Cell Line, Tumor; Cell Nucleus; DNA Damage; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Enzyme Activation; Etoposide; Humans; Leukemia; Methotrexate; Microtubules; Molecular Sequence Data; Neoplasm Proteins; Protein Transport; Tetrahydrofolate Dehydrogenase

2009
Downregulation of ANP32B, a novel substrate of caspase-3, enhances caspase-3 activation and apoptosis induction in myeloid leukemic cells.
    Carcinogenesis, 2010, Volume: 31, Issue:3

    Topics: Acetophenones; Antineoplastic Agents; Apoptosis; Benzopyrans; Camptothecin; Carcinoma; Caspase 3; Cell Line, Tumor; Cysteine Proteinase Inhibitors; Down-Regulation; Enzyme Activation; Female; Humans; Leukemia, Myeloid; Male; Neoplasm Proteins; Neoplasms; Nuclear Proteins; Recombinant Fusion Proteins; RNA Interference; RNA, Small Interfering; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity

2010
Dissociation of NSC606985 induces atypical ER-stress and cell death in prostate cancer cells.
    International journal of oncology, 2016, Volume: 49, Issue:2

    Topics: Apoptosis; Butylamines; Camptothecin; Cell Line, Tumor; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Heat-Shock Proteins; Humans; Male; Prostatic Neoplasms, Castration-Resistant; Protease Inhibitors; Taurochenodeoxycholic Acid

2016
Dual action of NSC606985 on cell growth and apoptosis mediated through PKCδ in prostatic cancer cells.
    International journal of oncology, 2017, Volume: 51, Issue:5

    Topics: Acetophenones; Apoptosis; Benzopyrans; Camptothecin; Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Humans; Male; Precision Medicine; Prostatic Neoplasms; Protein Kinase C-delta

2017