camptothecin has been researched along with nsc 725776 in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 6 (85.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bakshi, RP; Cushman, M; Morrell, A; Sang, D; Shapiro, TA | 1 |
| Agama, K; Agrawal, S; Cinelli, MA; Cushman, M; Dexheimer, TS; Morrell, AE; Pommier, Y | 1 |
| Agama, K; Antony, S; Cinelli, MA; Cushman, M; Dexheimer, TS; Mehta, A; Morrell, AE; Peterson, KE; Pommier, Y | 1 |
| Fukushima, T; Kogame, T; Maede, Y; Miki, T; Murai, J; Nakamura, T; Pommier, Y; Shimizu, H; Takeda, S | 1 |
| Dexheimer, TS; Guo, D; Nash, HA; Pommier, Y | 1 |
| Agama, K; Lorence, N; Neuman, KC; Pommier, Y; Seol, Y; Zhang, H | 1 |
| Agama, K; Brünner, N; Doroshow, JH; Jensen, NF; Knudsen, BR; Pfister, TD; Pommier, Y; Roy, A; Rømer, MU; Smith, DH; Stenvang, J; Zhang, HL | 1 |
7 other study(ies) available for camptothecin and nsc 725776
| Article | Year |
|---|---|
Activity of indenoisoquinolines against African trypanosomes.
Topics: Animals; DNA, Protozoan; Isoquinolines; Molecular Structure; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei | 2009 |
The structure-activity relationships of A-ring-substituted aromathecin topoisomerase I inhibitors strongly support a camptothecin-like binding mode.
Topics: Antineoplastic Agents; Camptothecin; DNA Topoisomerases, Type I; Enzyme Inhibitors; Humans; Isoquinolines; Models, Molecular; Protein Binding; Structure-Activity Relationship; Topoisomerase I Inhibitors | 2010 |
Alcohol-, diol-, and carbohydrate-substituted indenoisoquinolines as topoisomerase I inhibitors: investigating the relationships involving stereochemistry, hydrogen bonding, and biological activity.
Topics: Alcohols; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Hexoses; Humans; Hydrogen Bonding; Indenes; Models, Molecular; Pentoses; Quinolines; Stereoisomerism; Structure-Activity Relationship; Topoisomerase I Inhibitors | 2011 |
Differential and common DNA repair pathways for topoisomerase I- and II-targeted drugs in a genetic DT40 repair cell screen panel.
Topics: Autophagy; Benzodioxoles; Camptothecin; Cell Line; DNA Breaks, Double-Stranded; DNA Damage; DNA End-Joining Repair; DNA Repair; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Homologous Recombination; Humans; Isoquinolines; Signal Transduction; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors | 2014 |
Neuroprotection and repair of 3'-blocking DNA ends by glaikit (gkt) encoding Drosophila tyrosyl-DNA phosphodiesterase 1 (TDP1).
Topics: Animals; Antibiotics, Antineoplastic; Benzodioxoles; Bleomycin; Camptothecin; DNA Damage; DNA Repair; Drosophila melanogaster; Drosophila Proteins; Female; Hydrolysis; Isoquinolines; Longevity; Male; Mutagenesis, Insertional; Nerve Tissue Proteins; Oxidation-Reduction; Phosphoric Diester Hydrolases; Topoisomerase I Inhibitors | 2014 |
Single-Molecule Supercoil Relaxation Assay as a Screening Tool to Determine the Mechanism and Efficacy of Human Topoisomerase IB Inhibitors.
Topics: Antineoplastic Agents; Benzodioxoles; Camptothecin; Cell Line, Tumor; Cell Proliferation; Coumarins; DNA Cleavage; DNA Topoisomerases, Type I; DNA, Superhelical; Heterocyclic Compounds, 4 or More Rings; Humans; Inhibitory Concentration 50; Isoquinolines; Kinetics; Molecular Structure; Nucleic Acid Conformation; Substrate Specificity; Topoisomerase I Inhibitors | 2015 |
Characterization of DNA topoisomerase I in three SN-38 resistant human colon cancer cell lines reveals a new pair of resistance-associated mutations.
Topics: Benzodioxoles; Binding Sites; Camptothecin; Cell Line, Tumor; Chromosome Deletion; Colonic Neoplasms; DNA Topoisomerases, Type I; Drug Resistance, Neoplasm; Epirubicin; Etoposide; Gene Dosage; Guanidines; HCT116 Cells; HT29 Cells; Humans; Hydrazones; Irinotecan; Isoquinolines; Mutation | 2016 |