camptothecin has been researched along with nsc 706744 in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 9 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cushman, M; Fox, BM; Fukunaga, AK; Jayaraman, M; Kohlhagen, G; Pommier, Y; Strumberg, D; Vroman, JA | 1 |
| Cinelli, MA; Cushman, M; Dexheimer, TS; Morrell, A; Pommier, Y; Scher, ES | 1 |
| Cinelli, MA; Cordero, B; Cushman, M; Dexheimer, TS; Pommier, Y | 1 |
| Agama, K; Agrawal, S; Cinelli, MA; Cushman, M; Dexheimer, TS; Morrell, AE; Pommier, Y | 1 |
| Agama, K; Antony, S; Cinelli, MA; Cushman, M; Dexheimer, TS; Mehta, A; Morrell, AE; Peterson, KE; Pommier, Y | 1 |
| Agama, K; Barresi, E; Cosconati, S; Da Settimo, F; Di Leva, FS; Di Santo, R; La Motta, C; Marchand, C; Marinelli, L; Marini, AM; Novellino, E; Pommier, Y; Pugliesi, I; Salerno, S; Simorini, F; Taliani, S | 1 |
| Agama, K; Cushman, M; Lv, PC; Marchand, C; Pommier, Y | 1 |
| Dezhenkova, LG; Kalinina, AA; Kaluzhny, DN; Kubbutat, M; Luzikov, YN; Pommier, Y; Preobrazhenskaya, MN; Romanenko, VI; Schols, D; Shchekotikhin, AE; Shtil, AA; Tatarskiy, VV; Treshalin, MI; Treshalina, HM; Tsvetkov, VB; Volodina, YL | 1 |
| Agama, K; Cushman, M; Elsayed, MSA; Kiselev, E; Marchand, C; Plescia, CB; Pommier, Y; Ravji, A; Redon, CE; Wang, P; Zeleznik, O | 1 |
| Agama, K; Cushman, M; Elsayed, MSA; Freeman, JL; Horzmann, KA; Kiselev, E; Pommier, Y; Ravji, A; Redon, CE; Sethi, T; Su, Y; Wang, P | 1 |
| Agama, K; An, LK; Hu, DX; Kiselev, E; Marchand, C; Ofori-Atta, K; Pommier, Y; Ravji, A; Tang, WL; Wang, HW; Yang, H; Zhang, XR; Zhang, Y | 1 |
| Agama, K; An, LK; Chen, JW; Hu, DX; Pommier, Y; Tang, WL; Yang, H; Yu, Q; Zhang, Y | 1 |
12 other study(ies) available for camptothecin and nsc 706744
| Article | Year |
|---|---|
Synthesis of new indeno[1,2-c]isoquinolines: cytotoxic non-camptothecin topoisomerase I inhibitors.
Topics: Antineoplastic Agents; DNA, Superhelical; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Indenes; Isoquinolines; Structure-Activity Relationship; Topoisomerase I Inhibitors; Tumor Cells, Cultured | 2000 |
Design, synthesis, and biological evaluation of 14-substituted aromathecins as topoisomerase I inhibitors.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; DNA; DNA Topoisomerases, Type I; Drug Design; Humans; Indolizines; Ligands; Models, Molecular; Molecular Structure; Protein Binding; Quinolines; Structure-Activity Relationship; Topoisomerase I Inhibitors | 2008 |
Synthesis and biological evaluation of 14-(aminoalkyl-aminomethyl)aromathecins as topoisomerase I inhibitors: investigating the hypothesis of shared structure-activity relationships.
Topics: Antineoplastic Agents; Drug Evaluation, Preclinical; Enzyme Inhibitors; Magnetic Resonance Spectroscopy; Models, Molecular; Structure-Activity Relationship; Topoisomerase I Inhibitors | 2009 |
The structure-activity relationships of A-ring-substituted aromathecin topoisomerase I inhibitors strongly support a camptothecin-like binding mode.
Topics: Antineoplastic Agents; Camptothecin; DNA Topoisomerases, Type I; Enzyme Inhibitors; Humans; Isoquinolines; Models, Molecular; Protein Binding; Structure-Activity Relationship; Topoisomerase I Inhibitors | 2010 |
Alcohol-, diol-, and carbohydrate-substituted indenoisoquinolines as topoisomerase I inhibitors: investigating the relationships involving stereochemistry, hydrogen bonding, and biological activity.
Topics: Alcohols; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Hexoses; Humans; Hydrogen Bonding; Indenes; Models, Molecular; Pentoses; Quinolines; Stereoisomerism; Structure-Activity Relationship; Topoisomerase I Inhibitors | 2011 |
Phenylpyrazolo[1,5-a]quinazolin-5(4H)-one: a suitable scaffold for the development of noncamptothecin topoisomerase I (Top1) inhibitors.
Topics: DNA Topoisomerases, Type I; Drug Discovery; Heterocyclic Compounds, 3-Ring; Humans; Molecular Docking Simulation; Protein Conformation; Pyrroles; Quinazolines; Topoisomerase I Inhibitors | 2013 |
Design, synthesis, and biological evaluation of O-2-modified indenoisoquinolines as dual topoisomerase I-tyrosyl-DNA phosphodiesterase I inhibitors.
Topics: Drug Design; Humans; Isoquinolines; Models, Molecular; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Structure-Activity Relationship; Topoisomerase I Inhibitors | 2014 |
Discovery of antitumor anthra[2,3-b]furan-3-carboxamides: Optimization of synthesis and evaluation of antitumor properties.
Topics: Animals; Anthracenes; Antineoplastic Agents; Cell Line, Tumor; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Furans; Humans; Leukemia; Mice; Neoplasms; Protein Kinase Inhibitors; Structure-Activity Relationship; Topoisomerase Inhibitors | 2016 |
Synthesis and Biological Evaluation of the First Triple Inhibitors of Human Topoisomerase 1, Tyrosyl-DNA Phosphodiesterase 1 (Tdp1), and Tyrosyl-DNA Phosphodiesterase 2 (Tdp2).
Topics: Cells, Cultured; Humans; Phosphodiesterase Inhibitors; Structure-Activity Relationship; Topoisomerase I Inhibitors | 2017 |
Design and Synthesis of Chlorinated and Fluorinated 7-Azaindenoisoquinolines as Potent Cytotoxic Anticancer Agents That Inhibit Topoisomerase I.
Topics: Animals; Antineoplastic Agents; Cell Proliferation; DNA Cleavage; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Isoquinolines; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Topoisomerase I Inhibitors; Tumor Cells, Cultured; Zebrafish | 2017 |
Discovery, Synthesis, and Evaluation of Oxynitidine Derivatives as Dual Inhibitors of DNA Topoisomerase IB (TOP1) and Tyrosyl-DNA Phosphodiesterase 1 (TDP1), and Potential Antitumor Agents.
Topics: Antineoplastic Agents; Cell Line, Tumor; Chemistry Techniques, Synthetic; DNA Cleavage; DNA Topoisomerases, Type I; Drug Design; Humans; Models, Molecular; Phenanthridines; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Protein Conformation; Structure-Activity Relationship; Topoisomerase I Inhibitors | 2018 |
Synthesis and biological evaluation of 5-aminoethyl benzophenanthridone derivatives as DNA topoisomerase IB inhibitors.
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzophenanthridines; Breast Neoplasms; Cell Line, Tumor; DNA Damage; DNA Topoisomerases, Type I; Drug Screening Assays, Antitumor; Humans; Mice, Nude; Molecular Docking Simulation; Molecular Structure; Protein Binding; Structure-Activity Relationship; Topoisomerase I Inhibitors; Xenograft Model Antitumor Assays | 2019 |