Page last updated: 2024-08-22

camptothecin and novobiocin

camptothecin has been researched along with novobiocin in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19906 (23.08)18.7374
1990's10 (38.46)18.2507
2000's2 (7.69)29.6817
2010's8 (30.77)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Jun, KY; Jung, MJ; Kwon, Y; Lee, ES; Lee, EY; Lee, OH; Na, Y; Park Choo, HY1
Chang, IH; Jun, KY; Kwon, Y; Lee, E; Lee, ES; Na, Y; Park, SE1
Balakrishnan, G; Bhat, J; Chatterji, M; Dinesh, N; Ghorpade, S; Gorai, G; Guptha, S; Humnabadkar, V; Iyer, PS; Jena, LK; Kaur, P; Khadtare, P; Naik, M; Nandishaiah, R; Narayan, A; Naviri, LK; Panda, M; Ramachandran, V; Sharma, S1
Bist, G; Jun, KY; Kadayat, TM; Kwon, Y; Lee, ES; Park, S; Shrestha, A; Thapa Magar, TB1
AbuBakar, S; Albrecht, T; Boldogh, I; Deng, CZ; Fons, MP1
Adachi, K; Andrea, JE; Morgan, AR1
Collins, AR; Gedik, CM1
Andrews, PA; Howell, SB; Katz, EJ; Kling, KM; Vick, JS1
Baloch, Z; Coffman, FD; Cohen, S1
Debenham, PG; Smith, PJ; Watson, JV1
Desrosiers, R; Tanguay, RM1
Legerski, RJ; Penkala, JE; Peterson, CA; Wright, DA1
Duguet, M; Jaxel, C; Mirambeau, G; Panijel, J; Portemer, C; Taudou, G1
Gottesfeld, JM1
Mui, SC; Strauss, PR; Todt, JC; Zhang, LH1
Averbeck, D; Duchaud, E; Moustacchi, E; Rosselli, F1
Sitailo, LA; Zagariya, AM1
Ara, G; Eder, JP; Herman, TS; Holden, SA; Korbut, T; Schwartz, GN; Teicher, BA1
Falaschi, A; Ochem, A; Phan, TN; Tuteja, N; Tuteja, R1
Phan, TN; Tuteja, N1
Doi, S; Ikegami, Y; Kitazaki, T; Kohno, S; Mizuta, Y; Murase, K; Nakamura, Y; Nakatomi, K; Oka, M; Ross, DD; Shiozawa, K; Soda, H; Tsurutani, J; Yoshida, H; Yoshikawa, M1
Gan, L; Gan, Y; Guo, S; Zhang, X; Zhu, C1
Pham, XH; Tran, NQ; Tuteja, N; Tuteja, R1
González-Molleda, L; Wang, Y; Yuan, Y1

Other Studies

26 other study(ies) available for camptothecin and novobiocin

ArticleYear
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Synthesis, biological evaluation, and molecular docking study of 3-(3'-heteroatom substituted-2'-hydroxy-1'-propyloxy) xanthone analogues as novel topoisomerase IIα catalytic inhibitor.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:6

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Biocatalysis; Cell Line, Tumor; Cell Survival; DNA Topoisomerases, Type II; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HeLa Cells; HL-60 Cells; Humans; Models, Molecular; Molecular Structure; Stereoisomerism; Structure-Activity Relationship; Topoisomerase II Inhibitors; Xanthones

2011
3-(3-Butylamino-2-hydroxy-propoxy)-1-hydroxy-xanthen-9-one acts as a topoisomerase IIα catalytic inhibitor with low DNA damage.
    European journal of medicinal chemistry, 2013, Volume: 69

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Biocatalysis; Cell Line, Tumor; Cell Proliferation; DNA Damage; DNA Topoisomerases, Type II; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Structure-Activity Relationship; Topoisomerase II Inhibitors; Xanthones

2013
2-Phenylindole and Arylsulphonamide: Novel Scaffolds Bactericidal against Mycobacterium tuberculosis.
    ACS medicinal chemistry letters, 2014, Sep-11, Volume: 5, Issue:9

    Topics:

2014
Novel 2-aryl-4-(4'-hydroxyphenyl)-5H-indeno[1,2-b]pyridines as potent DNA non-intercalative topoisomerase catalytic inhibitors.
    European journal of medicinal chemistry, 2017, Jan-05, Volume: 125

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; DNA; DNA Topoisomerases, Type II; DNA-Binding Proteins; Humans; Molecular Docking Simulation; Pyridines; Structure-Activity Relationship; Topoisomerase II Inhibitors

2017
Modulation of the frequency of human cytomegalovirus-induced chromosome aberrations by camptothecin.
    Virology, 1992, Volume: 189, Issue:1

    Topics: Benzamides; Camptothecin; Cells, Cultured; Chromosome Aberrations; Cytomegalovirus Infections; DNA Repair; Dose-Response Relationship, Drug; Humans; Lymphocytes; Novobiocin; Poly(ADP-ribose) Polymerase Inhibitors

1992
Fluorometric assays for DNA topoisomerases and topoisomerase-targeted drugs: quantitation of catalytic activity and DNA cleavage.
    Molecular pharmacology, 1991, Volume: 40, Issue:4

    Topics: Amsacrine; Animals; Antineoplastic Agents; Camptothecin; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA, Circular; DNA, Single-Stranded; DNA, Superhelical; Ethidium; Fluorescence; Fluorometry; Hydrogen-Ion Concentration; Kinetics; Novobiocin; Teniposide; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

1991
Comparison of effects of fostriecin, novobiocin, and camptothecin, inhibitors of DNA topoisomerases, on DNA replication and repair in human cells.
    Nucleic acids research, 1990, Feb-25, Volume: 18, Issue:4

    Topics: Alkenes; Antibiotics, Antineoplastic; Camptothecin; Cell Membrane Permeability; DNA Damage; DNA Repair; DNA Replication; DNA, Neoplasm; HeLa Cells; Humans; Kinetics; Novobiocin; Polyenes; Pyrones; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Ultraviolet Rays

1990
Effect of topoisomerase modulators on cisplatin cytotoxicity in human ovarian carcinoma cells.
    European journal of cancer (Oxford, England : 1990), 1990, Volume: 26, Issue:6

    Topics: Antibiotics, Antineoplastic; Camptothecin; Cell Line; Cisplatin; DNA Topoisomerases, Type I; Drug Interactions; Etoposide; Female; Humans; Naphthoquinones; Novobiocin; Ovarian Neoplasms; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured

1990
Synergistic interactions between tumor necrosis factor and inhibitors of DNA topoisomerase I and II.
    Journal of immunology (Baltimore, Md. : 1950), 1990, Nov-01, Volume: 145, Issue:9

    Topics: Aminocoumarins; Camptothecin; Cell Line; Cell Survival; Coumarins; Drug Synergism; In Vitro Techniques; L Cells; Novobiocin; Teniposide; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Necrosis Factor-alpha

1990
A role of DNA topoisomerases in the active dissociation of DNA minor groove-ligand complexes. A flow cytometric study of inhibitor effects.
    Mutation research, 1989, Volume: 217, Issue:2

    Topics: Animals; Benzimidazoles; Camptothecin; Cell Line; Cell Nucleus; DNA; DNA Topoisomerases, Type I; Flow Cytometry; In Vitro Techniques; Ligands; Mice; Novobiocin; Thymidine Kinase; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; X-Rays

1989
Transcriptional inhibitors affecting topoisomerase II induce changes in histone methylation patterns similar to those induced by heat shock.
    Biochemical and biophysical research communications, 1989, Aug-15, Volume: 162, Issue:3

    Topics: Animals; Camptothecin; Cells, Cultured; Dactinomycin; Drosophila melanogaster; Ethidium; Histones; Hot Temperature; In Vitro Techniques; Methylation; Novobiocin; Teniposide; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Uridine

1989
Repair of UV-induced lesions in Xenopus laevis oocytes.
    Molecular and cellular biology, 1987, Volume: 7, Issue:12

    Topics: Animals; Camptothecin; Deoxycytosine Nucleotides; DNA; DNA Repair; DNA, Circular; DNA, Superhelical; Female; Kinetics; Microinjections; Novobiocin; Oocytes; Plasmids; Teniposide; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Transcription, Genetic; Ultraviolet Rays; Xenopus laevis

1987
Topoisomerase inhibitors induce irreversible fragmentation of replicated DNA in concanavalin A stimulated splenocytes.
    Biochemistry, 1988, Jan-12, Volume: 27, Issue:1

    Topics: Animals; Camptothecin; Concanavalin A; DNA; DNA Replication; DNA Topoisomerases, Type II; Etoposide; Lymphocyte Activation; Lymphocytes; Mice; Mice, Inbred C57BL; Novobiocin; Phenylmethylsulfonyl Fluoride; Spleen; Sulfones; Topoisomerase II Inhibitors

1988
Novobiocin inhibits RNA polymerase III transcription in vitro by a mechanism distinct from DNA topoisomerase II.
    Nucleic acids research, 1986, Mar-11, Volume: 14, Issue:5

    Topics: Aminocoumarins; Camptothecin; Coumarins; DNA-Directed RNA Polymerases; HeLa Cells; Novobiocin; RNA Polymerase III; RNA, Ribosomal; RNA, Transfer; Teniposide; Topoisomerase II Inhibitors; Transcription, Genetic

1986
Role for topoisomerases in the release of DNA into the detergent-soluble fraction of eukaryotic cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1986, Volume: 83, Issue:16

    Topics: Aminoacridines; Amsacrine; Animals; Camptothecin; Detergents; DNA; DNA Topoisomerases, Type I; Intercalating Agents; Kinetics; Mice; Novobiocin; Solubility; Spleen; Teniposide; Thymidine

1986
Comparison of the effects of DNA topoisomerase inhibitors on lymphoblasts from normal and Fanconi anemia donors.
    Mutation research, 1994, Volume: 325, Issue:4

    Topics: Camptothecin; Cell Division; Cells, Cultured; Chromosome Aberrations; DNA; DNA Damage; DNA Repair; Fanconi Anemia; Hematopoietic Stem Cells; Humans; Indoles; Isoquinolines; Lymphocytes; Methoxsalen; Nalidixic Acid; Novobiocin; Skin; Topoisomerase I Inhibitors

1994
The influence of antibiotics and antitumor agents on the relaxation activity of Pisum sativum leaf chloroplast topoisomerase I.
    Archives of biochemistry and biophysics, 1995, Jun-20, Volume: 320, Issue:1

    Topics: Amiloride; Amsacrine; Anti-Bacterial Agents; Antineoplastic Agents; Camptothecin; Chloroplasts; DNA Topoisomerases, Type I; DNA, Plant; Ethidium; Heparin; Indoles; Magnesium; Nalidixic Acid; Novobiocin; Pisum sativum; Polyamines; Topoisomerase I Inhibitors

1995
Modulation of antitumor alkylating agents by novobiocin, topotecan, and lonidamine.
    Cancer chemotherapy and pharmacology, 1993, Volume: 32, Issue:6

    Topics: Adenocarcinoma; Alkylating Agents; Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Camptothecin; Drug Synergism; Female; Fibrosarcoma; Humans; Indazoles; Male; Mice; Mice, Inbred C3H; Novobiocin; Topotecan; Tumor Cells, Cultured

1993
Inhibition of DNA unwinding and ATPase activities of human DNA helicase II by chemotherapeutic agents.
    Biochemical and biophysical research communications, 1997, Jul-30, Volume: 236, Issue:3

    Topics: Adenosine Triphosphatases; Amsacrine; Antineoplastic Agents; Aphidicolin; Camptothecin; Dactinomycin; Daunorubicin; DNA; DNA Helicases; Ellipticines; Enzyme Inhibitors; Ethidium; Etoposide; Genistein; Humans; Isoflavones; Nogalamycin; Novobiocin; Topoisomerase I Inhibitors

1997
Inhibition of pea chloroplast DNA helicase unwinding and ATPase activities by DNA-interacting ligands.
    Biochemical and biophysical research communications, 1998, Mar-27, Volume: 244, Issue:3

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amsacrine; Camptothecin; Chloroplasts; Dactinomycin; Daunorubicin; DNA Helicases; Ellipticines; Ethidium; Etoposide; Genistein; Hydrolysis; Intercalating Agents; Ligands; Nogalamycin; Novobiocin; Pisum sativum

1998
Reversal of breast cancer resistance protein (BCRP/ABCG2)-mediated drug resistance by novobiocin, a coumermycin antibiotic.
    International journal of cancer, 2004, Jan-01, Volume: 108, Issue:1

    Topics: Aminocoumarins; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Camptothecin; Coumarins; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Irinotecan; Lung Neoplasms; Mitoxantrone; Neoplasm Proteins; Novobiocin; Topoisomerase I Inhibitors; Topotecan; Tumor Cells, Cultured

2004
Effect of poly (ethylene oxide)-poly (propylene oxide)-poly (ethylene oxide) micelles on pharmacokinetics and intestinal toxicity of irinotecan hydrochloride: potential involvement of breast cancer resistance protein (ABCG2).
    The Journal of pharmacy and pharmacology, 2010, Volume: 62, Issue:8

    Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Bile; Biological Availability; Biological Transport; Biotransformation; Camptothecin; Cell Line; Chemistry, Pharmaceutical; Dogs; Drug Carriers; Drug Compounding; Epithelial Cells; Injections, Intravenous; Intestinal Mucosa; Intestines; Irinotecan; Lecithins; Male; Micelles; Novobiocin; Polyethylene Glycols; Propylene Glycols; Rats; Rats, Sprague-Dawley; Transfection

2010
Inhibition of unwinding and ATPase activities of pea MCM6 DNA helicase by actinomycin and nogalamycin.
    Plant signaling & behavior, 2011, Volume: 6, Issue:3

    Topics: Adenosine Triphosphatases; Camptothecin; Cisplatin; Dactinomycin; Daunorubicin; DNA Helicases; Ellipticines; Enzyme Inhibitors; Etoposide; Intercalating Agents; Mitoxantrone; Nogalamycin; Novobiocin; Pisum sativum; Plant Proteins

2011
Potent antiviral activity of topoisomerase I and II inhibitors against Kaposi's sarcoma-associated herpesvirus.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:2

    Topics: Antigens, Neoplasm; Antiviral Agents; Camptothecin; Cell Line; DNA Replication; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA-Binding Proteins; Enzyme Inhibitors; Gene Silencing; Herpesvirus 8, Human; Humans; Novobiocin; RNA, Small Interfering; Virion; Virus Replication

2012