Page last updated: 2024-08-22

camptothecin and nb 506

camptothecin has been researched along with nb 506 in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (88.89)18.2507
2000's1 (11.11)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kanzawa, F; Kubota, N; Nishio, K; Saijo, N1
Arioka, H; Bojanowski, K; Fukuda, M; Ishida, T; Kanzawa, F; Nishio, K; Ogasawara, H; Oka, M; Saijo, N1
Fukasawa, K; Hara, Y; Komatani, H; Nishimura, S; Okura, A; Suda, H; Yoshinari, T1
Saijo, N1
Harstrick, A; Hilger, RA; Rustum, YM; Seeber, S; Vanhoefer, U; Voigt, W; Yin, MB1
Bailly, C; Lansiaux, A1
Fukasawa, K; Komatani, H; Morita, M; Nishimura, S; Okura, A; Sakaizumi, N; Yoshida, E; Yoshinari, T1
Bailly, C; Carrasco, C; Hamy, F; Prudhomme, M; Rubin, E; Saleem, A; Vezin, H1
Bailly, C; Kohlhagen, G; Laco, G; Pommier, Y; Takebayashi, Y; Urasaki, Y1

Reviews

1 review(s) available for camptothecin and nb 506

ArticleYear
New chemotherapeutic agents for the treatment of non-small cell lung cancer: the Japanese experience.
    Chest, 1998, Volume: 113, Issue:1 Suppl

    Topics: Alkaloids; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carbazoles; Carcinoma, Non-Small-Cell Lung; Clinical Trials as Topic; Docetaxel; Glucosides; Humans; Irinotecan; Japan; Lung Neoplasms; Mitomycin; Mitomycins; Neoplasms, Experimental; Paclitaxel; Purine Nucleosides; Staurosporine; Taxoids; Treatment Outcome; Vinblastine; Vinorelbine

1998

Other Studies

8 other study(ies) available for camptothecin and nb 506

ArticleYear
Antitumor activities of a new indolocarbazole substance, NB-506, and establishment of NB-506-resistant cell lines, SBC-3/NB.
    Cancer research, 1995, Jul-01, Volume: 55, Issue:13

    Topics: Antineoplastic Agents; Camptothecin; Carbazoles; Carcinoma, Small Cell; Cell Nucleus; Drug Resistance; Glucosides; Humans; In Vitro Techniques; Irinotecan; Topoisomerase I Inhibitors; Tumor Cells, Cultured

1995
Synergism between cisplatin and topoisomerase I inhibitors, NB-506 and SN-38, in human small cell lung cancer cells.
    Cancer research, 1996, Feb-15, Volume: 56, Issue:4

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Carbazoles; Carcinoma, Small Cell; Cell Division; Cell Nucleus; Cell Survival; Cisplatin; DNA Repair; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Glucosides; Humans; Irinotecan; Lung Neoplasms; Topoisomerase I Inhibitors; Tumor Cells, Cultured

1996
Sequence-selective DNA cleavage by a topoisomerase I poison, NB-506.
    International journal of cancer, 1998, Jan-05, Volume: 75, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Base Sequence; Camptothecin; Carbazoles; DNA; DNA Repair; Glucosides; Molecular Sequence Data; Topoisomerase I Inhibitors

1998
Cellular determinants of resistance to indolocarbazole analogue 6-N-formylamino-12,13-dihydro-1,11-dihydroxy-13(beta-D-glucopyranosyl)- 5H-indolo[2,3-alpha]pyrrolo[3,4-c]carbazole-5,7(6H)-dione (NB-506), a novel potent topoisomerase I inhibitor, in multid
    Oncology research, 1997, Volume: 9, Issue:9

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Blotting, Northern; Camptothecin; Carbazoles; Cell Count; Chromatography, High Pressure Liquid; DNA Topoisomerases, Type I; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Fibrosarcoma; Glucosides; Humans; Multidrug Resistance-Associated Proteins; Ovarian Neoplasms; RNA, Messenger; Topoisomerase I Inhibitors; Tumor Cells, Cultured

1997
[NB 506].
    Bulletin du cancer, 1999, Volume: 86, Issue:3

    Topics: Animals; Antineoplastic Agents; Camptothecin; Carbazoles; Clinical Trials, Phase I as Topic; Drug Resistance; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Glucosides; Humans; Neoplasms; Topoisomerase I Inhibitors

1999
A new mechanism of acquisition of drug resistance by partial duplication of topoisomerase I.
    Cancer research, 1999, Jun-01, Volume: 59, Issue:11

    Topics: Animals; Antineoplastic Agents; Camptothecin; Carbazoles; DNA Damage; DNA Topoisomerases, Type I; DNA, Complementary; Drug Resistance, Neoplasm; Enzyme Inhibitors; Gene Rearrangement; Glucosides; Humans; Leukemia P388; Neoplasm Proteins; Reverse Transcriptase Polymerase Chain Reaction; Topoisomerase I Inhibitors

1999
The camptothecin-resistant topoisomerase I mutant F361S is cross-resistant to antitumor rebeccamycin derivatives. A model for topoisomerase I inhibition by indolocarbazoles.
    Biochemistry, 1999, Jul-06, Volume: 38, Issue:27

    Topics: Amino Acid Substitution; Aminoglycosides; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Base Sequence; Binding Sites; Camptothecin; Carbazoles; DNA Damage; DNA Topoisomerases, Type I; Drug Resistance, Neoplasm; Enzyme Inhibitors; Glucosides; Humans; Indoles; Intercalating Agents; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Recombinant Proteins; Serine; Topoisomerase I Inhibitors

1999
Use of camptothecin-resistant mammalian cell lines to evaluate the role of topoisomerase I in the antiproliferative activity of the indolocarbazole, NB-506, and its topoisomerase I binding site.
    Cancer research, 2001, Jan-15, Volume: 61, Issue:2

    Topics: Antineoplastic Agents; Binding Sites; Camptothecin; Carbazoles; Cell Survival; DNA Topoisomerases, Type I; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Glucosides; Humans; Intercalating Agents; Mutation; Stereoisomerism; Tumor Cells, Cultured

2001