Page last updated: 2024-08-22

camptothecin and navitoclax

camptothecin has been researched along with navitoclax in 5 studies

Research

Studies (5)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	4 (80.00)	24.3611
2020's	1 (20.00)	2.80

Authors

Authors	Studies
Jadhav, A; Kerns, E; Nguyen, K; Shah, P; Sun, H; Xu, X; Yan, Z; Yu, KR	1
Kabir, M; Kerns, E; Nguyen, K; Shah, P; Sun, H; Wang, Y; Xu, X; Yu, KR	1
Kabir, M; Kerns, E; Neyra, J; Nguyen, K; Nguyễn, ÐT; Shah, P; Siramshetty, VB; Southall, N; Williams, J; Xu, X; Yu, KR	1
Arzt, J; Busman, TA; Holen, KD; Lian, G; LoRusso, P; Rosen, LS; Rudersdorf, NS; Tolcher, AW; Vanderwal, CA; Waring, JF; Yang, J	1
Dimopoulos, NA; Fernandez Espinosa, DD; García, CP; Miriuka, SG; Romorini, L; Scassa, ME; Sevlever, GE; Videla Richardson, GA	1

Trials

1 trial(s) available for camptothecin and navitoclax

Article	Year
Safety, efficacy, and pharmacokinetics of navitoclax (ABT-263) in combination with irinotecan: results of an open-label, phase 1 study. Cancer chemotherapy and pharmacology, 2015, Volume: 76, Issue:5 Topics: Adenocarcinoma; Adult; Aged; Aniline Compounds; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Camptothecin; Colonic Neoplasms; Diarrhea; Disease Progression; Dose-Response Relationship, Drug; Febrile Neutropenia; Female; Hematologic Diseases; Humans; Irinotecan; Male; Middle Aged; Neoplasm Proteins; Neoplasms; Proto-Oncogene Proteins c-bcl-2; Salvage Therapy; Sulfonamides; Treatment Outcome	2015

Article

Year

Safety, efficacy, and pharmacokinetics of navitoclax (ABT-263) in combination with irinotecan: results of an open-label, phase 1 study.

Cancer chemotherapy and pharmacology, 2015, Volume: 76, Issue:5

Topics: Adenocarcinoma; Adult; Aged; Aniline Compounds; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Camptothecin; Colonic Neoplasms; Diarrhea; Disease Progression; Dose-Response Relationship, Drug; Febrile Neutropenia; Female; Hematologic Diseases; Humans; Irinotecan; Male; Middle Aged; Neoplasm Proteins; Neoplasms; Proto-Oncogene Proteins c-bcl-2; Salvage Therapy; Sulfonamides; Treatment Outcome

2015

Other Studies

4 other study(ies) available for camptothecin and navitoclax

Article	Year
Highly predictive and interpretable models for PAMPA permeability. Bioorganic & medicinal chemistry, 2017, 02-01, Volume: 25, Issue:3 Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Humans; Models, Biological; Organic Chemicals; Regression Analysis; Support Vector Machine	2017
Predictive models of aqueous solubility of organic compounds built on A large dataset of high integrity. Bioorganic & medicinal chemistry, 2019, 07-15, Volume: 27, Issue:14 Topics: Drug Discovery; Organic Chemicals; Pharmaceutical Preparations; Solubility	2019
Retrospective assessment of rat liver microsomal stability at NCATS: data and QSAR models. Scientific reports, 2020, 11-26, Volume: 10, Issue:1 Topics: Animals; Computer Simulation; Databases, Factual; Drug Discovery; High-Throughput Screening Assays; Liver; Machine Learning; Male; Microsomes, Liver; National Center for Advancing Translational Sciences (U.S.); Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Rats; Rats, Sprague-Dawley; Retrospective Studies; United States	2020
Human Pluripotent Stem Cells and Derived Neuroprogenitors Display Differential Degrees of Susceptibility to BH3 Mimetics ABT-263, WEHI-539 and ABT-199. PloS one, 2016, Volume: 11, Issue:3 Topics: Aniline Compounds; Ataxia Telangiectasia Mutated Proteins; bcl-X Protein; Bridged Bicyclo Compounds, Heterocyclic; Camptothecin; Cell Line; Human Embryonic Stem Cells; Humans; Induced Pluripotent Stem Cells; Neural Stem Cells; Proto-Oncogene Proteins c-bcl-2; Sulfonamides; Tumor Suppressor Protein p53	2016