camptothecin has been researched along with naphthoquinones in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (7.41) | 18.7374 |
| 1990's | 12 (44.44) | 18.2507 |
| 2000's | 5 (18.52) | 29.6817 |
| 2010's | 7 (25.93) | 24.3611 |
| 2020's | 1 (3.70) | 2.80 |
| Authors | Studies |
|---|---|
| Adamson, RH; Mead, JA; Sieber, SM | 1 |
| Dhar, ML | 1 |
| Andrews, PA; Howell, SB; Katz, EJ; Kling, KM; Vick, JS | 1 |
| Boothman, DA; Church, DR; Frydman, B; Hutson, P; Planchon, SM; Wilding, G; Witiak, DT; Wuerzberger, S | 1 |
| Buraczewska, I; Gasinska, A; Gradzka, I; Szumiel, I | 1 |
| Boorstein, RJ; Chiu, LN; Mahl, E; Mi, LJ | 1 |
| Boothman, DA | 1 |
| Averboukh, L; Li, CJ; Pardee, AB | 1 |
| Buraczewska, I; Kapiszewska, M; Kowalska-Loth, B; Lange, CS; Staron, K; Szumiel, I | 1 |
| Crumpacker, CS; Dezube, BJ; Li, CJ; Pardee, AB; Zhang, LJ | 1 |
| Frydman, B; Liu, AA; Liu, LF; Mao, Y; Marton, LJ; Neder, K; Sanders, MM; Sun, JS; Wang, HM; Witiak, DT; Wu, HY | 1 |
| Dichgans, J; Esser, P; Fontana, A; Groscurth, P; Schmidt, C; Weller, M; Winter, S | 1 |
| Boothman, DA; Bornmann, WG; Byers, KL; Pink, JJ; Planchon, SM; Wuerzberger, SM | 1 |
| Esser, P; Heimann, K; Hueber, A; Kociok, N; Weller, M; Winter, S | 1 |
| Boothman, DA; Bornmann, WG; Pink, JJ; Planchon, SM; Tagliarino, C; Varnes, ME | 1 |
| Hara, O; Ikegami, S; Iwamatsu, T; Shibata, Y; Yamashita, M | 1 |
| Burt, HM; Higo, T; Hunter, WL; Jackson, JK | 1 |
| Funanage, VL; Gómez-Curet, I; Scavina, M; Wang, W; Wu, CY | 1 |
| Castro, RE; Moreira, R; Rodrigues, CM; Santos, DM; Santos, MM; Viana, RJ | 1 |
| Du, J; Huang, C; Huang, S; Huang, W; Li, Y | 1 |
| Altieri, DC; Bosari, S; Faversani, A; Lopergolo, A; Moro, GP; Rivadeneira, D; Schultz, DC; Tosi, D; Vaira, V | 1 |
| Castelli, S; D'Annessa, I; Desideri, A | 1 |
| Binder, RJ; Bollinger, JC; Bowling, J; Chen, J; Chi, L; Fratt, EM; Hatfield, MJ; Hyatt, JL; Jeffries, C; Potter, PM; Scarborough, J | 1 |
| Kashihara, H; Kono, T; Kurita, N; Shimada, M; Takasu, C; Yismaw, WG; Yoshikawa, K | 1 |
| Kameoka, M; Nakamichi, K; Nukuzuma, C; Nukuzuma, S; Sugiura, S; Takegami, T; Tasaki, T | 1 |
| Balaña-Fouce, R; Castro, MÁ; Escudero-Martínez, JM; García, PA; Jambrina, PG; Pérez-Pertejo, Y; Reguera, RM; San Feliciano, A | 1 |
| Bando, H; Iino, S; Kadowaki, S; Kageyama, R; Kawazoe, A; Masuishi, T; Muro, K; Taniguchi, H; Yoshino, T | 1 |
2 review(s) available for camptothecin and naphthoquinones
| Article | Year |
|---|---|
Pharmacology of antitumor agents from higher plants.
Topics: Animals; Antineoplastic Agents, Phytogenic; Aporphines; Camptothecin; Carcinoma, Squamous Cell; Chemical Phenomena; Chemistry; Etoposide; Humans; Leukemia L1210; Leukemia, Experimental; Leukemia, Lymphoid; Maytansine; Melanoma; Naphthoquinones; Nasopharyngeal Neoplasms; Neoplasms; Neoplasms, Experimental; Phenanthrenes; Structure-Activity Relationship; Teniposide; Vinblastine; Vincristine | 1976 |
Topoisomerase 1B as a target against leishmaniasis.
Topics: Antiprotozoal Agents; Camptothecin; DNA Topoisomerases, Type I; Humans; Indoles; Isoquinolines; Leishmania; Leishmaniasis; Naphthoquinones; Protozoan Proteins; Quercetin | 2015 |
1 trial(s) available for camptothecin and naphthoquinones
| Article | Year |
|---|---|
Phase I study of napabucasin in combination with FOLFIRI + bevacizumab in Japanese patients with metastatic colorectal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Benzofurans; Bevacizumab; Camptothecin; Colorectal Neoplasms; Humans; Japan; Leucovorin; Naphthoquinones | 2021 |
24 other study(ies) available for camptothecin and naphthoquinones
| Article | Year |
|---|---|
Recent chemical and biological studies on natural products at the Central Drug Research Institute, Lucknow.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cats; Chemical Phenomena; Chemistry; Diuretics; Glycosides; Guinea Pigs; India; Naphthoquinones; Neuromuscular Blocking Agents; Parasympatholytics; Plant Extracts; Plants, Medicinal; Rabbits; Rats; Solanaceous Alkaloids | 1976 |
Effect of topoisomerase modulators on cisplatin cytotoxicity in human ovarian carcinoma cells.
Topics: Antibiotics, Antineoplastic; Camptothecin; Cell Line; Cisplatin; DNA Topoisomerases, Type I; Drug Interactions; Etoposide; Female; Humans; Naphthoquinones; Novobiocin; Ovarian Neoplasms; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1990 |
Beta-lapachone-mediated apoptosis in human promyelocytic leukemia (HL-60) and human prostate cancer cells: a p53-independent response.
Topics: Apoptosis; Breast Neoplasms; Camptothecin; Cell Division; Dimethyl Sulfoxide; Drug Screening Assays, Antitumor; G1 Phase; Humans; Leukemia, Promyelocytic, Acute; Male; Naphthoquinones; Prostatic Neoplasms; Resting Phase, Cell Cycle; Time Factors; Topoisomerase I Inhibitors; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1995 |
Effects of topoisomerase I-targeted drugs on radiation response of L5178Y sublines differentially radiation and drug sensitive.
Topics: Animals; Antibiotics, Antineoplastic; Camptothecin; Combined Modality Therapy; Drug Screening Assays, Antitumor; Leukemia L5178; Mice; Naphthoquinones; Radiation Tolerance; Radiation-Sensitizing Agents; Topoisomerase I Inhibitors; Tumor Cells, Cultured | 1995 |
Toxicity of camptothecin to Chinese hamster cells containing 5-hydroxymethyl-2'-deoxyuridine in their DNA.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Camptothecin; Cell Cycle; Cell Line; Cricetinae; Cricetulus; DNA Repair; Dose-Response Relationship, Drug; Drug Synergism; Irinotecan; Lung; Naphthoquinones; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; S Phase; Thymidine; Topoisomerase I Inhibitors | 1995 |
Enhanced malignant transformation is accompanied by increased survival recovery after ionizing radiation in Chinese hamster embryo fibroblasts.
Topics: Animals; Camptothecin; Cell Line, Transformed; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Cricetulus; DNA Repair; DNA Topoisomerases, Type I; Embryo, Mammalian; Fibroblasts; Mice; Mice, Nude; Naphthoquinones; Radiation Tolerance; Topoisomerase I Inhibitors | 1994 |
beta-Lapachone, a novel DNA topoisomerase I inhibitor with a mode of action different from camptothecin.
Topics: Animals; Camptothecin; Cattle; Cell Line; DNA, Kinetoplast; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Models, Structural; Molecular Structure; Naphthoquinones; Nucleic Acid Conformation; Plasmids; Protein Binding; Substrate Specificity; Thymus Gland; Topoisomerase I Inhibitors; Tumor Cells, Cultured | 1993 |
Reduced sensitivity to camptothecin of topoisomerase I from a L5178Y mouse lymphoma subline sensitive to X-radiation.
Topics: Animals; Antibiotics, Antineoplastic; Camptothecin; Cell Nucleus; Cell Survival; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Kinetics; Leukemia L5178; Mice; Naphthoquinones; Plasmids; Substrate Specificity; Topoisomerase I Inhibitors; Tumor Cells, Cultured; X-Rays | 1993 |
Three inhibitors of type 1 human immunodeficiency virus long terminal repeat-directed gene expression and virus replication.
Topics: Acute Disease; Antiviral Agents; Camptothecin; Cells, Cultured; Chronic Disease; Curcumin; Gene Expression Regulation, Viral; HIV Infections; HIV Long Terminal Repeat; HIV-1; In Vitro Techniques; Naphthoquinones; RNA, Viral; Topotecan; Virus Replication | 1993 |
Induction of DNA topoisomerase II-mediated DNA cleavage by beta-lapachone and related naphthoquinones.
Topics: Antineoplastic Agents, Alkylating; Camptothecin; DNA; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Humans; Mercaptoethanol; Naphthoquinones; Reverse Transcriptase Inhibitors; Topoisomerase I Inhibitors; Vitamin K; Yeasts | 1997 |
Topoisomerase-I inhibitors for human malignant glioma: differential modulation of p53, p21, bax and bcl-2 expression and of CD95-mediated apoptosis by camptothecin and beta-lapachone.
Topics: Apoptosis; bcl-2-Associated X Protein; Camptothecin; Cell Cycle Proteins; Cell Division; Cell Survival; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; fas Receptor; Glioma; Humans; Immunotherapy; Naphthoquinones; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Topoisomerase I Inhibitors; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1997 |
Induction of apoptosis in MCF-7:WS8 breast cancer cells by beta-lapachone.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Camptothecin; Cell Cycle; Cell Cycle Proteins; Cell Survival; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Female; Humans; Lethal Dose 50; Naphthoquinones; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Inhibitors; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1998 |
The topoisomerase I inhibitors, camptothecin and beta-lapachone, induce apoptosis of human retinal pigment epithelial cells.
Topics: Apoptosis; Camptothecin; Cell Culture Techniques; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Fas Ligand Protein; fas Receptor; Humans; Membrane Glycoproteins; Naphthoquinones; Pigment Epithelium of Eye; Topoisomerase I Inhibitors; Vitreoretinopathy, Proliferative | 1998 |
beta-Lapachone-induced apoptosis in human prostate cancer cells: involvement of NQO1/xip3.
Topics: Antibiotics, Antineoplastic; Apoptosis; Camptothecin; Caspases; Dicumarol; Enzyme Inhibitors; Humans; Male; NAD(P)H Dehydrogenase (Quinone); Naphthoquinones; Poly(ADP-ribose) Polymerases; Prostatic Neoplasms; Transformation, Genetic; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2001 |
Studies on fertilization in the teleost IV. Effects of aphidicolin and camptothecin on chromosome formation in fertilized medaka eggs.
Topics: Animals; Aphidicolin; Camptothecin; Chromosomes; DNA Polymerase I; DNA Topoisomerases; Etoposide; Fertilization; Meiosis; Mitogen-Activated Protein Kinases; Mitosis; Naphthoquinones; Oryzias; Protein Kinases; Topoisomerase Inhibitors; Zygote | 2002 |
Topoisomerase inhibitors as anti-arthritic agents.
Topics: Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Camptothecin; Cattle; Cell Proliferation; Cells, Cultured; Chick Embryo; Chondrocytes; Doxorubicin; Enzyme Inhibitors; Etoposide; Interleukin-1; Naphthoquinones; Neutrophils; Rabbits; Synovial Membrane; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Vitamin K 3 | 2008 |
Increased susceptibility of spinal muscular atrophy fibroblasts to camptothecin is p53-independent.
Topics: Apoptosis; Camptothecin; Cells, Cultured; DNA Topoisomerases, Type I; Fibroblasts; Humans; Muscular Atrophy, Spinal; Naphthoquinones; RNA, Small Interfering; Survival of Motor Neuron 1 Protein; Topoisomerase I Inhibitors; Tumor Suppressor Protein p53 | 2009 |
Naphtho[2,3-d]isoxazole-4,9-dione-3-carboxylates: potent, non-cytotoxic, antiapoptotic agents.
Topics: Animals; Apoptosis; bcl-X Protein; Camptothecin; Cytochromes c; Cytoprotection; Gene Expression Regulation; Hepatocytes; Molecular Structure; Naphthoquinones; Rats | 2009 |
Screening of anti-cancer agent using zebrafish: comparison with the MTT assay.
Topics: Animals; Antineoplastic Agents; Apoptosis; Biphenyl Compounds; Camptothecin; Cell Line, Tumor; Coloring Agents; Dimethyl Sulfoxide; Drug Screening Assays, Antitumor; Emodin; Gene Expression; Humans; Lignans; Naphthoquinones; Rotenone; Tetrazolium Salts; Thiazoles; Transcriptional Activation; Tumor Suppressor Protein p53; Zebrafish | 2012 |
Survivin family proteins as novel molecular determinants of doxorubicin resistance in organotypic human breast tumors.
Topics: Alternative Splicing; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Camptothecin; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA Damage; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Female; High-Throughput Screening Assays; Humans; Imidazoles; Inhibitor of Apoptosis Proteins; MCF-7 Cells; Naphthoquinones; Paclitaxel; Receptor, ErbB-2; Survivin; Tumor Suppressor Protein p53 | 2014 |
Selective Inhibitors of Human Liver Carboxylesterase Based on a β-Lapachone Scaffold: Novel Reagents for Reaction Profiling.
Topics: Camptothecin; Carboxylic Ester Hydrolases; Cell Line; Enzyme Inhibitors; Humans; Hydrolysis; Irinotecan; Liver; Molecular Docking Simulation; Naphthoquinones; Oseltamivir | 2017 |
TU-100 exerts a protective effect against bacterial translocation by maintaining the tight junction.
Topics: Animals; Antineoplastic Agents, Phytogenic; Bacterial Translocation; Camptothecin; Cells, Cultured; Claudin-4; Cytokines; Diarrhea; Humans; Inflammation Mediators; Irinotecan; Male; Naphthoquinones; Occludin; Phytotherapy; Rats, Wistar; Tight Junctions; Toll-Like Receptors; Zonula Occludens-1 Protein | 2017 |
CPT11 prevents virus replication in JCI cells persistently infected with JC polyomavirus.
Topics: Antiviral Agents; Camptothecin; Cell Line; Cell Proliferation; DNA Replication; DNA, Viral; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; JC Virus; Leukoencephalopathy, Progressive Multifocal; Naphthoquinones; Real-Time Polymerase Chain Reaction; Topoisomerase I Inhibitors; Topotecan; Viral Proteins; Virus Replication | 2017 |
Antileishmanial activity of terpenylquinones on Leishmania infantum and their effects on Leishmania topoisomerase IB.
Topics: Animals; Anthraquinones; Antiprotozoal Agents; Camptothecin; DNA Topoisomerases; Drug Resistance; Female; Hep G2 Cells; Humans; Leishmania infantum; Leishmaniasis, Visceral; Macrophages; Mice; Mice, Inbred BALB C; Molecular Docking Simulation; Naphthoquinones; Quinones; Spleen; Topoisomerase Inhibitors | 2019 |