Page last updated: 2024-08-22

camptothecin and melphalan

camptothecin has been researched along with melphalan in 27 studies

Research

Studies (27)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (3.70)	18.7374
1990's	7 (25.93)	18.2507
2000's	12 (44.44)	29.6817
2010's	5 (18.52)	24.3611
2020's	2 (7.41)	2.80

Authors

Authors	Studies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Wang, TW	1
Caldecott, K; Jeggo, P	1
Berger, NA; Chatterjee, S; Cheng, MF	1
Ali-Osman, F; Bigner, DD; Colvin, OM; Dolan, ME; Friedman, HS; Griffith, OW; Kaufmann, SH; Moschel, RC; Schold, SC	1
Cotter, TG; Fernandes, RS	1
Bissery, MC; Cheshire, PJ; Hallman, JC; Houghton, JA; Houghton, PJ; Mathieu-Boué, A	1
Caserini, C; Orlandi, L; Silvestrini, R; Supino, R; Vaglini, M; Zaffaroni, N; Zunino, F	1
Allavena, P; Broggini, M; Colella, G; D'Incalci, M; Giardina, G; Sen, S	1
Karaberis, E; Mourelatos, D	1
Aller, P; de Blas, E; Fernández, C; Sancho, P; Troyano, A	1
Berg, S; Bernstein, M; Blaney, SM; Cherrick, I; Kuttesch, N; Murry, DJ; Salama, V	1
Marchettini, P; Mohamed, F; Stuart, OA; Sugarbaker, PH; Urano, M	1
Cejka, P; Jiricny, J; Papouli, E	1
Alexander, HR; Bartlett, DL; Beresneva, T; Helsabeck, C; Libutti, SK; Pingpank, JF	1
Al Harbi, T; Al-Faris, N; Doyle, J; Gassas, A; Goia, C; Pappo, A	1
Glimelius, B; Graf, W; Grundmark, B; Larsson, R; Mahteme, H; Nygren, P; Påhlman, L; Tholander, B; von Heideman, A	1
Erlichman, C; Lingle, WL; Lukasiewicz, KB; McCollum, AK; Teneyck, CJ; Toft, DO	1
Burckhardt, G; Eckardt, R; Grottker, J; Gupta, S; Hagos, Y; Koepsell, H; Müller, GA; Shnitsar, V	1
Kumabe, T; Niizuma, H; Osawa, S; Saito, R; Sonoda, Y; Tominaga, T; Watanabe, M	1
Bauer, D; Biassoni, V; Casanova, M; Catania, S; De Pava, MV; Gandola, L; Indini, A; Massimino, M; Modena, P; Pecori, E; Podda, M; Polastri, D; Rampini, P; Schiavello, E	1
Han, MK; Merlin, D; Si, X; Viennois, E; Wang, L; Xiao, B; Zhang, M	1
Allen, JS; Cui, G; DiPersio, JF; Fiala, MA; Fletcher, S; Fontana, F; Lanza, GM; O'Neal, J; Pan, D; Rettig, M; Ritchey, J; Schmieder-Atteberry, AH; Scott, MJ; Simons, K; Vij, R; Yanaba, N; Yang, X	1
Paul, R; Paul, S	1

Other Studies

27 other study(ies) available for camptothecin and melphalan

Article	Year
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nature chemical biology, 2009, Volume: 5, Issue:10 Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
[Experimental studies on treatment schedule dependency of antitumor agents mecaphane & camptothecin (author's transl)]. Yao xue xue bao = Acta pharmaceutica Sinica, 1979, Volume: 14, Issue:7 Topics: Animals; Antineoplastic Agents; Camptothecin; Carcinoma, Ehrlich Tumor; Cyclophosphamide; Drug Administration Schedule; Melphalan; Mice; Vincristine	1979
Cross-sensitivity of gamma-ray-sensitive hamster mutants to cross-linking agents. Mutation research, 1991, Volume: 255, Issue:2 Topics: Animals; Camptothecin; Cell Line; Cell Survival; CHO Cells; Cisplatin; Cricetinae; Cricetulus; Cross-Linking Reagents; DNA Damage; Female; Guinea Pigs; Mechlorethamine; Melphalan; Mitomycin; Mutation; Radiation Tolerance; Ultraviolet Rays	1991
Schedule-dependent cytotoxicity of topotecan alone and in combination chemotherapy regimens. Oncology research, 1994, Volume: 6, Issue:6 Topics: Alkylating Agents; Animals; Antineoplastic Combined Chemotherapy Protocols; Aphidicolin; Camptothecin; Carmustine; Cell Cycle; Cell Death; Cell Line; Cisplatin; Cricetinae; Cricetulus; DNA Damage; DNA Repair; DNA, Neoplasm; Doxorubicin; Drug Synergism; Etoposide; Fibroblasts; Hydroxyurea; Lung; Melphalan; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Topotecan	1994
Elevated DNA polymerase alpha, DNA polymerase beta, and DNA topoisomerase II in a melphalan-resistant rhabdomyosarcoma xenograft that is cross-resistant to nitrosoureas and topotecan. Cancer research, 1994, Jul-01, Volume: 54, Issue:13 Topics: Alkyl and Aryl Transferases; Animals; Antineoplastic Agents; Camptothecin; Carmustine; DNA Polymerase I; DNA Polymerase II; DNA Topoisomerases, Type II; Drug Resistance; Drug Screening Assays, Antitumor; Female; Humans; Male; Melphalan; Mice; Mice, Inbred BALB C; Mice, Nude; Rhabdomyosarcoma; Topotecan; Transferases; Transplantation, Heterologous	1994
Apoptosis or necrosis: intracellular levels of glutathione influence mode of cell death. Biochemical pharmacology, 1994, Aug-17, Volume: 48, Issue:4 Topics: Alkylating Agents; Apoptosis; Camptothecin; Cell Death; Cell Line; Chlorambucil; Dactinomycin; DNA; Glutathione; Humans; Melphalan; Necrosis	1994
Therapeutic efficacy of the topoisomerase I inhibitor 7-ethyl-10-(4-[1-piperidino]-1-piperidino)-carbonyloxy-camptothecin against human tumor xenografts: lack of cross-resistance in vivo in tumors with acquired resistance to the topoisomerase I inhibitor Cancer research, 1993, Jun-15, Volume: 53, Issue:12 Topics: Adolescent; Adult; Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Child; Colonic Neoplasms; Drug Administration Schedule; Drug Resistance; Drug Screening Assays, Antitumor; Female; Humans; Irinotecan; Male; Melphalan; Mice; Mice, Inbred CBA; Neoplasm Transplantation; Rhabdomyosarcoma; Topotecan; Transplantation, Heterologous; Tumor Cells, Cultured; Vincristine	1993
Modulation of melphalan cytotoxic activity in human melanoma cell lines. Anti-cancer drugs, 1996, Volume: 7, Issue:5 Topics: Antineoplastic Agents, Alkylating; Blotting, Northern; Camptothecin; Drug Interactions; Enzyme Inhibitors; Ethacrynic Acid; Humans; Melanoma; Melphalan; Temperature; Topoisomerase I Inhibitors; Topotecan; Tumor Cells, Cultured	1996
IFN-beta partially counteracts inhibition of natural killer activity induced by some antitumor agents. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 1998, Volume: 18, Issue:2 Topics: Antineoplastic Agents; Camptothecin; Cisplatin; Cytotoxicity Tests, Immunologic; Distamycins; Doxorubicin; Etoposide; Immunosuppressive Agents; Interferon-beta; Killer Cells, Natural; Melphalan; Nitrogen Mustard Compounds; Recombinant Proteins	1998
Enhanced cytogenetic and antitumor effects by 9-nitrocamptothecin and antineoplastics. Teratogenesis, carcinogenesis, and mutagenesis, 2000, Volume: 20, Issue:3 Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell Division; Drug Screening Assays, Antitumor; Epirubicin; Humans; Leukemia P388; Lymphocytes; Melphalan; Mice; Sister Chromatid Exchange	2000
Effect of glutathione depletion on antitumor drug toxicity (apoptosis and necrosis) in U-937 human promonocytic cells. The role of intracellular oxidation. The Journal of biological chemistry, 2001, Dec-14, Volume: 276, Issue:50 Topics: Adenosine Triphosphate; Alkylating Agents; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Buthionine Sulfoximine; Camptothecin; Cell Death; Cisplatin; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Doxorubicin; Enzyme Inhibitors; Etoposide; Flow Cytometry; Glutathione; Humans; Hydrogen Peroxide; Hypoxia; Immunoblotting; Melphalan; Membrane Potentials; Mitochondria; Monocytes; Necrosis; Nucleic Acid Synthesis Inhibitors; Oxygen; Radiation-Protective Agents; Reactive Oxygen Species; Spectrometry, Fluorescence; Time Factors; Topoisomerase I Inhibitors; U937 Cells	2001
Influence of phenytoin on the disposition of irinotecan: a case report. Journal of pediatric hematology/oncology, 2002, Volume: 24, Issue:2 Topics: Adolescent; Anticonvulsants; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Brain Neoplasms; Camptothecin; Carboplatin; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Disease Progression; Drug Interactions; Enzyme Induction; Etoposide; Hematopoietic Stem Cell Transplantation; Humans; Irinotecan; Male; Melphalan; Mixed Function Oxygenases; Neoplasm Recurrence, Local; Ondansetron; Phenobarbital; Phenytoin; Pineal Gland; Pinealoma; Prodrugs; Salvage Therapy; Seizures	2002
Thermal enhancement of new chemotherapeutic agents at moderate hyperthermia. Annals of surgical oncology, 2003, Volume: 10, Issue:4 Topics: Animals; Antineoplastic Agents; Camptothecin; Deoxycytidine; Drug Screening Assays, Antitumor; Fibrosarcoma; Gemcitabine; Hyperthermia, Induced; Irinotecan; Melphalan; Mice; Mice, Inbred C3H; Organoplatinum Compounds; Oxaliplatin; Paclitaxel	2003
Dependence of the cytotoxicity of DNA-damaging agents on the mismatch repair status of human cells. Cancer research, 2004, May-15, Volume: 64, Issue:10 Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Base Pair Mismatch; Camptothecin; Carrier Proteins; Cell Line; Cisplatin; DNA Repair; Drug Screening Assays, Antitumor; Etoposide; Furocoumarins; Humans; Inhibitory Concentration 50; Melphalan; Mitomycin; MutL Protein Homolog 1; Neoplasm Proteins; Nitrosourea Compounds; Nuclear Proteins	2004
Isolated hepatic perfusion for the treatment of patients with colorectal cancer liver metastases after irinotecan-based therapy. Annals of surgical oncology, 2005, Volume: 12, Issue:2 Topics: Adult; Aged; Antineoplastic Agents; Camptothecin; Chemotherapy, Cancer, Regional Perfusion; Colorectal Neoplasms; Disease Progression; Female; Humans; Hyperthermia, Induced; Irinotecan; Liver Neoplasms; Male; Melphalan; Middle Aged; Neoplasm Staging; Treatment Failure; Treatment Outcome	2005
Does consolidation with autologous stem cell transplantation improve the outcome of children with metastatic or relapsed Ewing sarcoma? Pediatric blood & cancer, 2007, Volume: 49, Issue:2 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Camptothecin; Carboplatin; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Epirubicin; Etoposide; Follow-Up Studies; Humans; Ifosfamide; Infection Control; Kaplan-Meier Estimate; Melphalan; Neoplasm Recurrence, Local; Peripheral Blood Stem Cell Transplantation; Postoperative Care; Retrospective Studies; Risk; Salvage Therapy; Sarcoma, Ewing; Topotecan; Transplantation Conditioning; Transplantation, Autologous; Treatment Failure; Vincristine	2007
Heterogeneous activity of cytotoxic drugs in patient samples of peritoneal carcinomatosis. European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2008, Volume: 34, Issue:5 Topics: Camptothecin; Cisplatin; Cytotoxins; Doxorubicin; Drug Resistance, Neoplasm; Female; Fluorouracil; Humans; Irinotecan; Male; Melphalan; Mitomycin; Organoplatinum Compounds; Oxaliplatin; Perioperative Care; Peritoneal Neoplasms; Tumor Cells, Cultured	2008
Cisplatin abrogates the geldanamycin-induced heat shock response. Molecular cancer therapeutics, 2008, Volume: 7, Issue:10 Topics: Antineoplastic Agents; Benzoquinones; Camptothecin; Cell Line, Tumor; Chromatin; Cisplatin; DNA-Binding Proteins; Drug Resistance, Neoplasm; Drug Synergism; Heat Shock Transcription Factors; Heat-Shock Response; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Melphalan; Protein Binding; Transcription Factors; Up-Regulation	2008
Expression of human organic cation transporter 3 in kidney carcinoma cell lines increases chemosensitivity to melphalan, irinotecan, and vincristine. Cancer research, 2009, Feb-15, Volume: 69, Issue:4 Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Division; Cell Line, Tumor; Cell Survival; CHO Cells; Cricetinae; Cricetulus; DNA Primers; Humans; Irinotecan; Kidney Neoplasms; Melphalan; Organic Cation Transport Proteins; Reverse Transcriptase Polymerase Chain Reaction; Transfection; Vincristine	2009
Infratentorial brain metastases of pediatric non-epithelial malignant tumors: three case reports. Brain tumor pathology, 2011, Volume: 28, Issue:2 Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Carboplatin; Chemotherapy, Adjuvant; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Dactinomycin; Doxorubicin; Etoposide; Humans; Ifosfamide; Infant; Infratentorial Neoplasms; Irinotecan; Melphalan; Neoplasm Metastasis; Neuroblastoma; Rhabdomyosarcoma; Thiotepa; Topotecan; Vincristine	2011
Relapse in medulloblastoma: what can be done after abandoning high-dose chemotherapy? A mono-institutional experience. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2013, Volume: 29, Issue:7 Topics: Administration, Intravenous; Administration, Oral; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Cerebellar Neoplasms; Child; Child, Preschool; Cisplatin; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Cranial Irradiation; Dacarbazine; Deoxycytidine; Disease Progression; Disease-Free Survival; Etoposide; Female; Gemcitabine; Humans; Irinotecan; Male; Medulloblastoma; Melphalan; Neoplasm Recurrence, Local; Organoplatinum Compounds; Oxaliplatin; Patient Selection; Quality of Life; Radiotherapy; Retrospective Studies; Salvage Therapy; Temozolomide; Young Adult	2013
Hyaluronic acid-functionalized polymeric nanoparticles for colon cancer-targeted combination chemotherapy. Nanoscale, 2015, Nov-14, Volume: 7, Issue:42 Topics: Animals; Caco-2 Cells; Camptothecin; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Curcumin; Drug Carriers; Drug Synergism; Humans; Hyaluronic Acid; Immunoglobulin G; Lactic Acid; Male; Melphalan; Mice; Mice, Inbred C57BL; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers	2015
VLA4-Targeted Nanoparticles Hijack Cell Adhesion-Mediated Drug Resistance to Target Refractory Myeloma Cells and Prolong Survival. Clinical cancer research : an official journal of the American Association for Cancer Research, 2021, 04-01, Volume: 27, Issue:7 Topics: Animals; Camptothecin; Cell Adhesion; Cell Line, Tumor; Dexamethasone; Drug Resistance, Neoplasm; Humans; Integrin alpha4beta1; Melphalan; Mice; Mice, Inbred C57BL; Multiple Myeloma; Nanoparticles; Topoisomerase I Inhibitors	2021
Exploration on the drug solubility enhancement in aqueous medium with the help of endo-functionalized molecular tubes: a computational approach. Physical chemistry chemical physics : PCCP, 2021, Sep-14, Volume: 23, Issue:34 Topics: Albendazole; Camptothecin; Clopidogrel; Drug Industry; Fluorouracil; Indomethacin; Melphalan; Molecular Dynamics Simulation; ortho-Aminobenzoates; Solubility; Water	2021