Page last updated: 2024-08-22

camptothecin and leupeptins

camptothecin has been researched along with leupeptins in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's5 (41.67)29.6817
2010's5 (41.67)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Piette, J; Piret, B; Schoonbroodt, S1
Bukowski, RM; Ganapathi, MK; Ganapathi, R; Grabowski, DR; Tabata, M; Tabata, R1
Ganapathi, R; Tabata, M1
Ahn, JS; Bae, EY; He, L; Jeong, SJ; Kim, A; Kim, BY; Kim, CH; Kim, KE; Kim, SO; Kwon, OS; Lee, MS; Moon, A; Shim, JH; Yoon, DY1
Furukawa, T; Ishikawa, T; Morishima, Y; Nakagawa, H; Osawa, Y; Tamura, A; Wakabayashi, K1
Fukuda, M; Koike, A; Ohta, T; Takeshita, T; Wu, W1
Brodie, KM; Henderson, BR1
Abe, M; Harada, M; Itou, M; Kawaguchi, T; Koga, H; Kuromatsu, R; Okuda, K; Sakata, M; Sata, M; Sumie, S; Taniguchi, E; Ueno, T; Yamagishi, S1
Sakasai, R; Teraoka, H; Tibbetts, RS1
Jaeger, C; Kratz, F; Merfort, I; Naumann, K; Schmich, K1
Ikeda, M; Ishida, K; Kume, K; Nishizuka, SS; Shimura, T; Takemoto, K; Young, L1
Chen, Q; Hu, J; Liu, J; Luo, X; Meng, Z; Ni, Z; Sun, Y; Tang, L; Wang, X; Xiang, F; Zhang, M; Zhang, Z; Zhu, L1

Other Studies

12 other study(ies) available for camptothecin and leupeptins

ArticleYear
The ATM protein is required for sustained activation of NF-kappaB following DNA damage.
    Oncogene, 1999, Apr-01, Volume: 18, Issue:13

    Topics: Adolescent; Age Factors; Antineoplastic Agents, Phytogenic; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Brain Neoplasms; Camptothecin; Cell Cycle Proteins; Cells, Cultured; Child; Child, Preschool; DNA Damage; DNA-Activated Protein Kinase; DNA-Binding Proteins; Enzyme Inhibitors; Fibroblasts; Gene Expression Regulation; Glioblastoma; Humans; I-kappa B Proteins; Leupeptins; NF-kappa B; NF-KappaB Inhibitor alpha; Nuclear Proteins; Phosphoric Monoester Hydrolases; Protease Inhibitors; Protein Serine-Threonine Kinases; Proteins; Radiation Tolerance; Recombinant Fusion Proteins; Topoisomerase I Inhibitors; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53; Tumor Suppressor Proteins

1999
Roles of NF-kappaB and 26 S proteasome in apoptotic cell death induced by topoisomerase I and II poisons in human nonsmall cell lung carcinoma.
    The Journal of biological chemistry, 2001, Mar-16, Volume: 276, Issue:11

    Topics: Apoptosis; Camptothecin; Carcinoma, Non-Small-Cell Lung; Cisplatin; DNA; DNA Damage; DNA-Binding Proteins; Enzyme Inhibitors; Etoposide; Humans; I-kappa B Proteins; Irinotecan; Leupeptins; Lung Neoplasms; NF-kappa B; NF-KappaB Inhibitor alpha; Paclitaxel; Peptide Hydrolases; Proteasome Endopeptidase Complex; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

2001
NF-kappa B activation in topoisomerase I inhibitor-induced apoptotic cell death in human non-small cell lung cancer.
    Annals of the New York Academy of Sciences, 2000, Volume: 922

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Carcinoma, Non-Small-Cell Lung; DNA-Binding Proteins; Enzyme Inhibitors; Humans; I-kappa B Proteins; Irinotecan; Leupeptins; Lung Neoplasms; NF-kappa B; NF-KappaB Inhibitor alpha; Topoisomerase I Inhibitors; Transfection; Tumor Cells, Cultured

2000
Caspase-3 activation as a key factor for HBx-transformed cell death.
    Cell proliferation, 2008, Volume: 41, Issue:5

    Topics: Camptothecin; Caspase 3; Cell Death; Cell Line, Transformed; Cell Proliferation; Cell Survival; Endoplasmic Reticulum; Enzyme Activation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Leupeptins; NF-kappa B; Oligopeptides; Proto-Oncogene Proteins c-akt; Signal Transduction; Trans-Activators; Transcriptional Activation; Viral Regulatory and Accessory Proteins

2008
Major SNP (Q141K) variant of human ABC transporter ABCG2 undergoes lysosomal and proteasomal degradations.
    Pharmaceutical research, 2009, Volume: 26, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Camptothecin; Cell Line; Cell Survival; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Humans; Immunoblotting; Irinotecan; Leupeptins; Lysosomes; Macrolides; Microscopy, Fluorescence; Neoplasm Proteins; Polymorphism, Single Nucleotide; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Stability; RNA, Messenger; Time Factors; Ubiquitin

2009
Perturbation of DNA repair pathways by proteasome inhibitors corresponds to enhanced chemosensitivity of cells to DNA damage-inducing agents.
    Cancer chemotherapy and pharmacology, 2009, Volume: 64, Issue:5

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Cell Nucleus; Cell Survival; Comet Assay; DNA Damage; DNA Repair; Epirubicin; Female; HeLa Cells; Humans; Immunohistochemistry; Irinotecan; Leupeptins; Oligopeptides; Proteasome Inhibitors; Ubiquitin

2009
Differential modulation of BRCA1 and BARD1 nuclear localisation and foci assembly by DNA damage.
    Cellular signalling, 2010, Volume: 22, Issue:2

    Topics: Active Transport, Cell Nucleus; Apoptosis; BRCA1 Protein; Camptothecin; Cell Line, Tumor; Cell Nucleolus; DNA Damage; DNA Repair; Down-Regulation; Etoposide; Humans; Leupeptins; Phosphorylation; Radiation, Ionizing; RNA, Small Interfering; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases; Ultraviolet Rays

2010
Pigment epithelium-derived factor inhibits lysosomal degradation of Bcl-xL and apoptosis in HepG2 cells.
    The American journal of pathology, 2010, Volume: 176, Issue:1

    Topics: Apoptosis; bcl-X Protein; Camptothecin; Carcinoma, Hepatocellular; Cell Cycle; Cyclophilins; Densitometry; Eye Proteins; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Hep G2 Cells; Humans; Leupeptins; Liver; Liver Neoplasms; Lysosomes; Macrolides; Nerve Growth Factors; Protein Processing, Post-Translational; Recombinant Proteins; RNA, Messenger; Serpins

2010
Proteasome inhibition suppresses DNA-dependent protein kinase activation caused by camptothecin.
    DNA repair, 2010, Jan-02, Volume: 9, Issue:1

    Topics: Camptothecin; Cell Line, Tumor; Cyclin-Dependent Kinases; DNA Replication; DNA-Activated Protein Kinase; Enzyme Activation; Humans; Leupeptins; Phosphorylation; Protease Inhibitors; Proteasome Inhibitors; Replication Protein A

2010
Noxa/Mcl-1 balance influences the effect of the proteasome inhibitor MG-132 in combination with anticancer agents in pancreatic cancer cell lines.
    Anti-cancer drugs, 2012, Volume: 23, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Camptothecin; Caspase 3; Caspase 7; Cell Line, Tumor; Doxorubicin; Humans; Leupeptins; Myeloid Cell Leukemia Sequence 1 Protein; NF-kappa B; Paclitaxel; Pancreatic Neoplasms; Proteasome Inhibitors; Proto-Oncogene Proteins c-bcl-2

2012
Systematic Protein Level Regulation via Degradation Machinery Induced by Genotoxic Drugs.
    Journal of proteome research, 2016, Jan-04, Volume: 15, Issue:1

    Topics: Apoptosis; Camptothecin; Cisplatin; DNA Damage; Fluorouracil; HCT116 Cells; Humans; Irinotecan; Leupeptins; Mutagens; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Proteolysis; Proteome

2016
Decreasing Arl4c expression by inhibition of AKT signal in human lung adenocarcinoma cells.
    Life sciences, 2020, Apr-01, Volume: 246

    Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; ADP-Ribosylation Factors; Blotting, Western; Camptothecin; Cell Line, Tumor; Chromones; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Leupeptins; Lung Neoplasms; Morpholines; Proto-Oncogene Proteins c-akt; Signal Transduction; Smoking

2020